DK92582A - Alkylendiaminderivater n-oxider eller syreadditionssalte deraf deres fremstilling og anvendelse som antiarytmiske laegemidler - Google Patents

Alkylendiaminderivater n-oxider eller syreadditionssalte deraf deres fremstilling og anvendelse som antiarytmiske laegemidler Download PDF

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Publication number
DK92582A
DK92582A DK92582A DK92582A DK92582A DK 92582 A DK92582 A DK 92582A DK 92582 A DK92582 A DK 92582A DK 92582 A DK92582 A DK 92582A DK 92582 A DK92582 A DK 92582A
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DK
Denmark
Prior art keywords
antiarithmic
alkylendiamine
medicines
oxides
derivatives
Prior art date
Application number
DK92582A
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English (en)
Other versions
DK161514C (da
DK161514B (da
Inventor
Z Zubovics
L Toldy
G Rabloczky
A Varro
S Elek
I Elekes
Original Assignee
Alkaloida Vegyeszeti Gyar
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Filing date
Publication date
Application filed by Alkaloida Vegyeszeti Gyar filed Critical Alkaloida Vegyeszeti Gyar
Publication of DK92582A publication Critical patent/DK92582A/da
Publication of DK161514B publication Critical patent/DK161514B/da
Application granted granted Critical
Publication of DK161514C publication Critical patent/DK161514C/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D203/08—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom
    • C07D203/14—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom with carbocyclic rings directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/20—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C291/00—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00
    • C07C291/02—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00 containing nitrogen-oxide bonds
    • C07C291/04—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00 containing nitrogen-oxide bonds containing amino-oxide bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D203/08—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom
    • C07D203/12—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DK092582A 1981-03-04 1982-03-03 Analogifremgangsmaade til fremstilling af alkylendiaminderivater eller n-oxider eller syreadditionssalte deraf DK161514C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU53981 1981-03-04
HU81539A HU184392B (en) 1981-03-04 1981-03-04 Process for producing new alkylene-diamine derivatives

Publications (3)

Publication Number Publication Date
DK92582A true DK92582A (da) 1982-09-05
DK161514B DK161514B (da) 1991-07-15
DK161514C DK161514C (da) 1991-12-23

Family

ID=10950064

Family Applications (1)

Application Number Title Priority Date Filing Date
DK092582A DK161514C (da) 1981-03-04 1982-03-03 Analogifremgangsmaade til fremstilling af alkylendiaminderivater eller n-oxider eller syreadditionssalte deraf

Country Status (16)

Country Link
US (1) US4922021A (da)
JP (1) JPS57163348A (da)
AT (1) AT380682B (da)
BE (1) BE892329A (da)
CA (1) CA1181755A (da)
DE (1) DE3207813A1 (da)
DK (1) DK161514C (da)
ES (1) ES8307711A1 (da)
FI (1) FI72713C (da)
FR (1) FR2509296A1 (da)
GB (1) GB2098599B (da)
HU (1) HU184392B (da)
IT (1) IT1190711B (da)
NL (1) NL8200850A (da)
SE (1) SE460603B (da)
SU (1) SU1246890A3 (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT388912B (de) * 1983-06-23 1989-09-25 Alkaloida Vegyeszeti Gyar Verfahren zur herstellung von alkylendiaminen und ihren salzen
DE19956786A1 (de) * 1999-11-25 2001-05-31 Basf Ag Verfahren zur Herstellung optisch aktiver Amine
CA2683653A1 (en) * 2007-04-10 2008-10-16 Boehringer Ingelheim International Gmbh Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB547301A (en) * 1940-11-14 1942-08-21 Ernst Bergman Improvements in and relating to the synthesis of aromatic and heterocyclic n-(amino-alkyl) substituted amines
GB604363A (en) * 1944-03-31 1948-07-02 Chem Ind Basel Manufacture of monoaryl tertiary amines or salts thereof
US2921094A (en) * 1958-01-17 1960-01-12 Us Vitamin Pharm Corp omega-(n-methyl-2, 6-dialkylanilino) alkyl halides
US3068235A (en) * 1960-01-05 1962-12-11 U S Vitamin And Pharmaceutical Quaternary ammonium salts of omega-(n-methyl-2,6-dimethylanilino) alkyl halides
FR965M (da) * 1960-02-04 1961-11-27
GB1016071A (en) * 1961-02-15 1966-01-05 Smith Kline French Lab New guanidine derivatives and process for preparing the same
US3205136A (en) * 1962-12-24 1965-09-07 Smith Kline French Lab Antidepressant phenyloxyalkylamines
US3328249A (en) * 1965-06-21 1967-06-27 Sterling Drug Inc Process for counteracting depressive states
DE1643240A1 (de) * 1966-09-16 1971-06-24 Boehringer Sohn Ingelheim Verfahren zur Herstellung neuer racemischer oder optisch aktiver 1-Phenoxy-2-aminoalkane
US3923813A (en) * 1969-12-19 1975-12-02 Christiaens Sa A Derivatives of 2-aminoindanes
FR2073286A1 (en) * 1969-12-23 1971-10-01 Robert Et Carriere Labo Substd anilines - with antirheumatic analgesic and antiinflammatory activity
US3702327A (en) * 1970-12-28 1972-11-07 Aldrich Chem Co Inc N-beta-1-(3-phenylimidazolidin-2-one)ethyl 4,4-ethylene dioxypiperidines
US3981872A (en) * 1972-10-06 1976-09-21 A. Christiaens Societe Anonyme Derivatives of 2-amino-(1,2,3,4-tetrahydronaphthalene)
GB1410162A (en) * 1973-03-01 1975-10-15 Manuf Prod Pharma 2-aminoindane derivatives
ZA793568B (en) * 1978-07-26 1981-02-25 Duphar Int Res Algicidal composition
US4322434A (en) * 1979-05-04 1982-03-30 Schering Corporation N-Substituted-4-(polyfluoro-2-hydroxy-2-propyl)anilines and compounds related thereto
DD155614A1 (de) * 1980-12-22 1982-06-23 Dieter Lehmann Verfahren zur herstellung von derivaten des n-phenylaethylendiamins

Also Published As

Publication number Publication date
CA1181755A (en) 1985-01-29
GB2098599A (en) 1982-11-24
DK161514C (da) 1991-12-23
JPH0229669B2 (da) 1990-07-02
JPS57163348A (en) 1982-10-07
SU1246890A3 (ru) 1986-07-23
ATA83282A (de) 1985-11-15
DE3207813C2 (da) 1993-08-12
FI820752L (fi) 1982-09-05
IT1190711B (it) 1988-02-24
NL8200850A (nl) 1982-10-01
GB2098599B (en) 1984-11-21
FI72713C (fi) 1987-07-10
BE892329A (fr) 1982-09-02
DK161514B (da) 1991-07-15
SE8201308D0 (sv) 1982-03-03
FI72713B (fi) 1987-03-31
ES510155A0 (es) 1983-07-01
FR2509296A1 (fr) 1983-01-14
DE3207813A1 (de) 1982-09-16
AT380682B (de) 1986-06-25
FR2509296B1 (da) 1985-02-15
US4922021A (en) 1990-05-01
HU184392B (en) 1984-08-28
SE460603B (sv) 1989-10-30
IT8219930A0 (it) 1982-03-03
ES8307711A1 (es) 1983-07-01

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