FR2073286A1 - Substd anilines - with antirheumatic analgesic and antiinflammatory activity - Google Patents

Substd anilines - with antirheumatic analgesic and antiinflammatory activity

Info

Publication number
FR2073286A1
FR2073286A1 FR6944618A FR6944618A FR2073286A1 FR 2073286 A1 FR2073286 A1 FR 2073286A1 FR 6944618 A FR6944618 A FR 6944618A FR 6944618 A FR6944618 A FR 6944618A FR 2073286 A1 FR2073286 A1 FR 2073286A1
Authority
FR
France
Prior art keywords
substd
antirheumatic
anilines
analgesic
antiinflammatory activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR6944618A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ROBERT ET CARRIERE LABO
Original Assignee
ROBERT ET CARRIERE LABO
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ROBERT ET CARRIERE LABO filed Critical ROBERT ET CARRIERE LABO
Priority to FR6944618A priority Critical patent/FR2073286A1/en
Publication of FR2073286A1 publication Critical patent/FR2073286A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Abstract

Cpds. are of formula : and their acid-addn. salts (where R is H, one or more NO2, alkyl, alkoxy; R1 is H, CnH2n. B where CnH2n is alkylM esp. where n = 1, 2 or 3, B = aliphatic or heterocyclic amino gp. e.g. Me2NH or pyrrolidon; R2 is H, aliphatic acyl, araliphatic acyl in which the aryl ring carries one or more substituents, e.g. halogen, alkoxy, aryloxycarbonyl in which the ring is opt. substd., the gp. where R3, R4 = H, alkyl or may be joined to form an N-heterocyclic ring e.g. pyrrolidino; provided that R1 and R2 are not both H; R1 is not H or -CH2. CH2. NEt2 when R is 4-NO2 and R2 is Co.Et; R is not H when R1 is -CH2CH2NEt2 and R2 is -CO.NMe2). The cpds. are analgesics, anti-inflammatory and antirheumatic agents, and intermediates.
FR6944618A 1969-12-23 1969-12-23 Substd anilines - with antirheumatic analgesic and antiinflammatory activity Withdrawn FR2073286A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR6944618A FR2073286A1 (en) 1969-12-23 1969-12-23 Substd anilines - with antirheumatic analgesic and antiinflammatory activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR6944618A FR2073286A1 (en) 1969-12-23 1969-12-23 Substd anilines - with antirheumatic analgesic and antiinflammatory activity

Publications (1)

Publication Number Publication Date
FR2073286A1 true FR2073286A1 (en) 1971-10-01

Family

ID=9045047

Family Applications (1)

Application Number Title Priority Date Filing Date
FR6944618A Withdrawn FR2073286A1 (en) 1969-12-23 1969-12-23 Substd anilines - with antirheumatic analgesic and antiinflammatory activity

Country Status (1)

Country Link
FR (1) FR2073286A1 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2509296A1 (en) * 1981-03-04 1983-01-14 Alkaloida Vegyeszeti Gyar NOVEL ALKYLENEDIAMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING SAME
WO2001055107A2 (en) * 2000-01-28 2001-08-02 Melacure Therapeutics Ab Aromatic amines and amides acting on the melanocortin receptors
US6846953B1 (en) 1999-05-10 2005-01-25 Warner Lambert Company Aromatic amides

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2509296A1 (en) * 1981-03-04 1983-01-14 Alkaloida Vegyeszeti Gyar NOVEL ALKYLENEDIAMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING SAME
US6846953B1 (en) 1999-05-10 2005-01-25 Warner Lambert Company Aromatic amides
WO2001055107A2 (en) * 2000-01-28 2001-08-02 Melacure Therapeutics Ab Aromatic amines and amides acting on the melanocortin receptors
WO2001055107A3 (en) * 2000-01-28 2002-01-17 Melacure Therapeutics Ab Aromatic amines and amides acting on the melanocortin receptors

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Legal Events

Date Code Title Description
ST Notification of lapse