DK91083A - Fremgangsmaade til fremstilling af thiazol-derivater - Google Patents

Fremgangsmaade til fremstilling af thiazol-derivater Download PDF

Info

Publication number
DK91083A
DK91083A DK91083A DK91083A DK91083A DK 91083 A DK91083 A DK 91083A DK 91083 A DK91083 A DK 91083A DK 91083 A DK91083 A DK 91083A DK 91083 A DK91083 A DK 91083A
Authority
DK
Denmark
Prior art keywords
sub
sup
alkyl
aryl
alkynyl
Prior art date
Application number
DK91083A
Other languages
Danish (da)
English (en)
Other versions
DK91083D0 (da
Inventor
Richard Paul Pioch
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DK91083D0 publication Critical patent/DK91083D0/da
Publication of DK91083A publication Critical patent/DK91083A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/194—Radicals derived from thio- or thiono carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Earth Drilling (AREA)
  • Inert Electrodes (AREA)
  • Treating Waste Gases (AREA)
  • Supply Devices, Intensifiers, Converters, And Telemotors (AREA)
  • Fats And Perfumes (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
DK91083A 1982-03-19 1983-02-25 Fremgangsmaade til fremstilling af thiazol-derivater DK91083A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/360,034 US4474794A (en) 1982-03-19 1982-03-19 N-Thiazolylmethylthioalkyl-N1 -alkenyl (or alkynyl)guanidines and related compounds

Publications (2)

Publication Number Publication Date
DK91083D0 DK91083D0 (da) 1983-02-25
DK91083A true DK91083A (da) 1983-09-20

Family

ID=23416322

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91083A DK91083A (da) 1982-03-19 1983-02-25 Fremgangsmaade til fremstilling af thiazol-derivater

Country Status (22)

Country Link
US (1) US4474794A (cs)
EP (1) EP0091220B1 (cs)
JP (1) JPS58170773A (cs)
KR (1) KR840004091A (cs)
AT (1) ATE27156T1 (cs)
AU (1) AU1254583A (cs)
CA (1) CA1190547A (cs)
CS (1) CS236788B2 (cs)
DD (1) DD207376A5 (cs)
DE (1) DE3371514D1 (cs)
DK (1) DK91083A (cs)
ES (1) ES8405386A1 (cs)
FI (1) FI830879A7 (cs)
GB (1) GB2116973B (cs)
GR (1) GR77882B (cs)
IL (1) IL68152A0 (cs)
NZ (1) NZ203605A (cs)
PH (1) PH18504A (cs)
PL (1) PL241066A1 (cs)
PT (1) PT76397B (cs)
RO (1) RO85385B (cs)
ZA (1) ZA831882B (cs)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA869438B (en) * 1985-12-18 1988-07-27 Lilly Co Eli Synthesis of nizatidine
EP0285681B1 (de) * 1987-04-06 1993-03-10 HEUMANN PHARMA GMBH & CO Verfahren zur Herstellung von Nitroethenderivaten
NL9000132A (nl) * 1990-01-19 1991-08-16 Cedona Pharm Bv Nieuwe thiazoolderivaten.
EP4196793A1 (en) 2020-08-11 2023-06-21 Université de Strasbourg H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4200578A (en) * 1978-12-18 1980-04-29 Bristol-Myers Company Thiazole derivatives
US4375547A (en) * 1980-10-02 1983-03-01 Eli Lilly And Company N-Methyl-N'-2-([(2-dimethylaminomethyl)-4-thiazolyl]methylthio)ethyl 2-nitro-1,1-ethenediamine

Also Published As

Publication number Publication date
GR77882B (cs) 1984-09-25
ES520791A0 (es) 1984-06-01
DK91083D0 (da) 1983-02-25
FI830879L (fi) 1983-09-20
DD207376A5 (de) 1984-02-29
GB2116973B (en) 1985-08-29
ATE27156T1 (de) 1987-05-15
CS236788B2 (en) 1985-05-15
FI830879A0 (fi) 1983-03-16
RO85385A (ro) 1984-11-25
JPS58170773A (ja) 1983-10-07
EP0091220A2 (en) 1983-10-12
FI830879A7 (fi) 1983-09-20
GB2116973A (en) 1983-10-05
US4474794A (en) 1984-10-02
RO85385B (ro) 1984-11-30
ZA831882B (en) 1984-11-28
NZ203605A (en) 1985-10-11
GB8307201D0 (en) 1983-04-20
CA1190547A (en) 1985-07-16
AU1254583A (en) 1983-09-22
PT76397A (en) 1983-04-01
PT76397B (en) 1986-02-04
EP0091220B1 (en) 1987-05-13
PH18504A (en) 1985-08-02
PL241066A1 (en) 1985-01-02
EP0091220A3 (en) 1984-05-23
ES8405386A1 (es) 1984-06-01
DE3371514D1 (en) 1987-06-19
IL68152A0 (en) 1983-06-15
KR840004091A (ko) 1984-10-06

Similar Documents

Publication Publication Date Title
KR830007624A (ko) 헤테로 사이클릭 화합물의 제조방법
ES8707948A1 (es) Un procedimiento para la preparacion de derivados de aza-indol.
RU2003127736A (ru) Ингибитора металлопротеиназ
KR940005633A (ko) 약제학적으로 유용한 항경련제 설파메이트의 이미데이트 유도체
DK0971878T3 (da) Aminforbindelser, fremstillingen og anvendelsen deraf som inhibitorer af amyloid-beta-produktion
DK142084D0 (da) N-phenyl-n'-cycloalkylalkanoyl-piperaziner og fremgangsmaade til fremstilling heraf
KR910007883A (ko) 퀴놀린 유도체, 그의 제조방법 및 용도
EP0125803A3 (en) Pharmaceutically active dihydropyridines
DK562683D0 (da) Substituerede 1,4-dihydropyridiner eller salte deraf,deres fremstilling og anvendelse
DK91083A (da) Fremgangsmaade til fremstilling af thiazol-derivater
FI851611A0 (fi) Heterocykliska aminokomponenter.
KR900018042A (ko) 부텐산 유도체
DK185984D0 (da) Disubstituerede polymethyleniminer,fremgangsmaader til deres fremstilling og farmaceutiske kompositioner indeholdende dem
EP0094727A3 (en) Substituted heterocyclyl phenylformamidines, processes for their preparation and their pharmaceutical use
NZ194777A (en) N-aminoalkyl-n'-(2-chloroethyl)-n'-nitroso-ureas and pharmaceutical compositions
CA2242571A1 (en) Amino compounds and angiotensin iv receptor agonists
ATE5586T1 (de) Neue aminopropanol-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel.
ATE15796T1 (de) Benzhydrylsulfinylethylamine, verfahren zu deren herstellung und verwendung in der therapeutik.
ATE44741T1 (de) 2-(n-substituierte guanidino)-4heteroarylthiazole als mittel gegen geschwuere.
ES8604531A1 (es) Procedimiento para preparar pirido(1,4)benzodiazepinas
BG46157A3 (bg) Метод за получаване на n-алкил(ен)-n-(о,о-дву- заместен тиофосфорил- n', n' - двузаместени глицинамиди
TH630A (th) N-(อาริลไธโออัลคิล)-n'-(อมิโนอัลคิล)ยูเรีย
RU98109784A (ru) Фармацевтически активные производные хиназолина
TH3061A (th) 2-(อัลคอกซิมิโนอัลคอกซีคาร์บอนิล)-เฟนนิลซัลโฟนิลซัลโฟนิลยูเรีย
TH68407A (th) 3-ไพริดิล-4-แอริลพิร์โรลที่ถูกแทนที่ และวิธีการรักษาโรคและการป้องกันโรคที่เกี่ยวข้อง

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment