DK82793A - Heterocycliske urinstof- eller carbamidsyrederivater, deres fremstilling og anvendelse - Google Patents
Heterocycliske urinstof- eller carbamidsyrederivater, deres fremstilling og anvendelseInfo
- Publication number
- DK82793A DK82793A DK082793A DK82793A DK82793A DK 82793 A DK82793 A DK 82793A DK 082793 A DK082793 A DK 082793A DK 82793 A DK82793 A DK 82793A DK 82793 A DK82793 A DK 82793A
- Authority
- DK
- Denmark
- Prior art keywords
- phenyl
- lower alkyl
- alkyl
- alkoxy
- heterocyclic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/04—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- C07D451/06—Oxygen atoms
- C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
- C07D453/04—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems having a quinolyl-4, a substituted quinolyl-4 or a alkylenedioxy-quinolyl-4 radical linked through only one carbon atom, attached in position 2, e.g. quinine
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Otolaryngology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB878730193A GB8730193D0 (en) | 1987-12-24 | 1987-12-24 | Heterocyclic compounds |
GB888819728A GB8819728D0 (en) | 1988-08-19 | 1988-08-19 | Heterocyclic compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
DK82793D0 DK82793D0 (da) | 1993-07-08 |
DK82793A true DK82793A (da) | 1993-07-08 |
Family
ID=26293248
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK710488A DK710488A (da) | 1987-12-24 | 1988-12-20 | Heterocycliske urinstof- eller carbamidsyrederivater, deres fremstilling og anvendelse |
DK082793A DK82793A (da) | 1987-12-24 | 1993-07-08 | Heterocycliske urinstof- eller carbamidsyrederivater, deres fremstilling og anvendelse |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK710488A DK710488A (da) | 1987-12-24 | 1988-12-20 | Heterocycliske urinstof- eller carbamidsyrederivater, deres fremstilling og anvendelse |
Country Status (18)
Country | Link |
---|---|
US (2) | US4983600A (da) |
EP (2) | EP0361629B1 (da) |
JP (1) | JP2588265B2 (da) |
KR (1) | KR970009588B1 (da) |
AT (2) | ATE67200T1 (da) |
AU (1) | AU611976B2 (da) |
CA (1) | CA1334095C (da) |
DE (2) | DE3850255T2 (da) |
DK (2) | DK710488A (da) |
ES (2) | ES2051867T3 (da) |
FI (1) | FI95031C (da) |
GB (1) | GB2213816B (da) |
GR (1) | GR3002701T3 (da) |
HU (1) | HU204267B (da) |
IE (2) | IE63474B1 (da) |
IL (1) | IL88644A (da) |
PH (1) | PH27437A (da) |
PT (1) | PT89286B (da) |
Families Citing this family (60)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK443489D0 (da) * | 1989-09-08 | 1989-09-08 | Ferrosan As | Substituerede urinstofforbindelser, deres fremstilling og anvendelse |
GB8922622D0 (en) * | 1989-10-07 | 1989-11-22 | Wyeth John & Brother Ltd | Aroylureas |
GB2236751B (en) | 1989-10-14 | 1993-04-28 | Wyeth John & Brother Ltd | Heterocyclic compounds |
DK40890D0 (da) * | 1990-02-16 | 1990-02-16 | Ferrosan As | Substituerede urinstofforbindelser, deres fremstilling og anvendelse |
DE4009565A1 (de) * | 1990-03-24 | 1991-09-26 | Merck Patent Gmbh | Indolderivate |
GB9106571D0 (en) * | 1991-03-27 | 1991-05-15 | Erba Carlo Spa | Derivatives of substituted imidazol-2-one and process for their preparation |
US5223613A (en) * | 1990-04-27 | 1993-06-29 | G. D. Searle & Co. | Azatetracycle compounds and process of preparing same |
US5140023A (en) * | 1990-04-27 | 1992-08-18 | G. D. Searle & Co. | Azatetracycle compounds |
JP3122671B2 (ja) * | 1990-05-23 | 2001-01-09 | 協和醗酵工業株式会社 | 複素環式化合物 |
US5319085A (en) * | 1990-12-28 | 1994-06-07 | Kyowa Hakko Kogyo Co., Ltd. | Quinoline derivative having serotonin-3 receptor antagonizing activity |
DE69200921T2 (de) * | 1991-03-01 | 1995-05-04 | Pfizer | 1-azabicyclo[3.2.2]nonan-3-aminderivate. |
US5234921A (en) * | 1991-03-07 | 1993-08-10 | G. D. Searle & Co. | Meso-azacyclic amides of imidazopyridine carboxylic acids and analogs thereof as pharmaceuticals |
US5137893A (en) * | 1991-03-07 | 1992-08-11 | G. D. Searle & Co. | Pharmaceutically useful meso-azacyclic amides of imidazopyridine carboxylic acids and analogs thereof |
US5227377A (en) * | 1991-03-07 | 1993-07-13 | G. D. Searle & Co. | Meso-azacyclic amides of certain bicyclic carboxylic acids |
US5260303A (en) * | 1991-03-07 | 1993-11-09 | G. D. Searle & Co. | Imidazopyridines as serotonergic 5-HT3 antagonists |
US5196547A (en) * | 1991-03-07 | 1993-03-23 | G. D. Searle & Co. | Meso-azacyclic amides of imidazopyridine carboxylic acids and analogs thereof |
US5219850A (en) * | 1991-03-07 | 1993-06-15 | G. D. Searle & Co. | Pharmaceutically useful meso-azacyclic amides of imidazopyridine carboxylic acids and analogs thereof |
US5516782A (en) * | 1991-03-07 | 1996-05-14 | G. D. Searle & Co. | New meso-azacyclic aromatic acid amides and esters as novel serotonergic agents |
JPH05507942A (ja) * | 1991-03-07 | 1993-11-11 | ジー.ディー.サール アンド カンパニー | 新規セロトニン作動性剤としての新規なmeso―アザ環式芳香族酸アミド化合物およびエステル化合物 |
GB9121835D0 (en) * | 1991-10-15 | 1991-11-27 | Smithkline Beecham Plc | Pharmaceuticals |
JPH05310732A (ja) * | 1992-03-12 | 1993-11-22 | Mitsubishi Kasei Corp | シンノリン−3−カルボン酸誘導体 |
US5190953A (en) * | 1992-03-26 | 1993-03-02 | A. H. Robins Company, Incorporated | Heterocyclic carboxylic acid amides and esters of azabicyclic compounds as gastric prokinetic, antiemetic, anxiolytic and antiarrhythmic agents |
US5244907A (en) * | 1992-03-26 | 1993-09-14 | A. H. Robins Company, Incorporated | Carbocyclic carboxylic acid amides and esters of azabicyclic compounds as gastric prokinetic, antiemetic, anxiolytic and antiarrhythmic agents |
GB9206989D0 (en) * | 1992-03-31 | 1992-05-13 | Glaxo Group Ltd | Chemical compounds |
JP3236298B2 (ja) * | 1992-03-31 | 2001-12-10 | グラクソ、グループ、リミテッド | 置換フェニルカルバメート類および尿素類 |
GB2269747B (en) * | 1992-08-19 | 1996-06-05 | Wyeth John & Brother Ltd | Aroyl-ureas as pharmaceuticals, particularly 5-ht3 antagonists |
GB9217629D0 (en) * | 1992-08-19 | 1992-09-30 | Wyeth John & Brother Ltd | Aroylureas |
GB9224144D0 (en) * | 1992-11-18 | 1993-01-06 | Erba Carlo Spa | Phenyl-imidazolidinone derivatives and process for their preparation |
GB9314174D0 (en) * | 1993-07-08 | 1993-08-18 | American Home Prod | 5-ht3-antagonists |
DE69739869D1 (de) * | 1996-03-20 | 2010-06-17 | Univ Wake Forest Health Sciences | Sigma-2 rezeptoren als biomarkierer der tumorzellenproliferation |
US6676925B1 (en) * | 1996-03-20 | 2004-01-13 | Wake Forest University | Sigma-2 receptors as biomarkers of tumor cell proliferation |
US6022884A (en) | 1997-11-07 | 2000-02-08 | Amgen Inc. | Substituted pyridine compounds and methods of use |
US6669925B1 (en) | 2000-04-27 | 2003-12-30 | Wake Forest University | Sigma-2 receptors as biomarkers of tumor cell proliferation |
US6492385B2 (en) | 2000-08-18 | 2002-12-10 | Pharmacia & Upjohn Company | Quinuclidine-substituted heteroaryl moieties for treatment of disease |
AU2001282873A1 (en) | 2000-08-18 | 2002-03-04 | Pharmacia And Upjohn Company | Quinuclidine-substituted aryl compounds for treatment of disease |
JP2004506735A (ja) | 2000-08-18 | 2004-03-04 | ファルマシア・アンド・アップジョン・カンパニー | 疾患治療用キヌクリジン置換アリール化合物 |
US6500840B2 (en) | 2000-08-21 | 2002-12-31 | Pharmacia & Upjohn Company | Quinuclidine-substituted heteroaryl moieties for treatment of disease |
WO2002015662A2 (en) | 2000-08-21 | 2002-02-28 | Pharmacia & Upjohn Company | Quinuclidine-substituted heteroaryl moieties for treatment of disease (nicotinic acetylcholine receptor antagonists |
PE20021019A1 (es) | 2001-04-19 | 2002-11-13 | Upjohn Co | Grupos azabiciclicos sustituidos |
AR036040A1 (es) | 2001-06-12 | 2004-08-04 | Upjohn Co | Compuestos de heteroarilo multiciclicos sustituidos con quinuclidinas y composiciones farmaceuticas que los contienen |
AR036041A1 (es) * | 2001-06-12 | 2004-08-04 | Upjohn Co | Compuestos aromaticos heterociclicos sustituidos con quinuclidina y composiciones farmaceuticas que los contienen |
CA2455773A1 (en) * | 2001-08-24 | 2003-03-06 | Pharmacia & Upjohn Company | Substituted-aryl 7-aza¬2.2.1|bicycloheptanes for the treatment of disease |
EP1419161A1 (en) | 2001-08-24 | 2004-05-19 | PHARMACIA & UPJOHN COMPANY | Substituted-heteroaryl-7-aza 2.2.1]bicycloheptanes for the treatment of disease |
EP1425286B1 (en) * | 2001-09-12 | 2007-02-28 | Pharmacia & Upjohn Company LLC | Substituted 7-aza-[2.2.1]bicycloheptanes for the treatment of diseases |
NZ531786A (en) | 2001-10-02 | 2006-10-27 | Upjohn Co | Azabicyclic-substituted fused-heteroaryl compounds for the treatment of disease |
WO2003037896A1 (en) * | 2001-10-26 | 2003-05-08 | Pharmacia & Upjohn Company | N-azabicyclo-substituted hetero-bicyclic carboxamides as nachr agonists |
US6849620B2 (en) | 2001-10-26 | 2005-02-01 | Pfizer Inc | N-(azabicyclo moieties)-substituted hetero-bicyclic aromatic compounds for the treatment of disease |
JP2005511613A (ja) * | 2001-11-08 | 2005-04-28 | ファルマシア アンド アップジョン カンパニー リミティド ライアビリティー カンパニー | 疾患治療用アザビシクロ置換ヘテロアリール化合物 |
BR0214016A (pt) | 2001-11-09 | 2004-10-13 | Upjohn Co | Compostos azabicìclico-fenil-fundido heterocìclicos e seu uso como ligandos alfa 7 nachr |
US6852716B2 (en) | 2002-02-15 | 2005-02-08 | Pfizer Inc | Substituted-aryl compounds for treatment of disease |
JP2005523288A (ja) * | 2002-02-19 | 2005-08-04 | ファルマシア・アンド・アップジョン・カンパニー・エルエルシー | 疾病治療用の縮合した二環式−n−架橋−複素環式芳香族カルボキサミド |
AU2003217275A1 (en) * | 2002-02-19 | 2003-09-09 | Pharmacia And Upjohn Company | Azabicyclic compounds for the treatment of disease |
BR0307874A (pt) * | 2002-02-20 | 2004-12-28 | Upjohn Co | Atividade de compostos azabicìclicos com receptor de acetilcolina nicotìnica alfa7 |
WO2004013137A1 (en) * | 2002-08-01 | 2004-02-12 | Pharmacia & Upjohn Company Llc | 1h-pyrazole and 1h-pyrrole-azabicyclic compounds with alfa-7 nachr activity |
WO2004039815A2 (en) * | 2002-11-01 | 2004-05-13 | Pharmacia & Upjohn Company Llc | Compounds having both alpha7 nachr agonist and 5ht antagonist activity for treatment of cns diseases |
WO2005099698A1 (ja) * | 2004-04-15 | 2005-10-27 | Eisai R & D Management Co., Ltd. | 安定化された4-アミノ-5-クロロ-N-[(1R,3r,5S)-8-メチル-8-アザビシクロ[3.2.1]オクタ-3-イル]-2-[1-メチルブタ-2-インイルオキシ]ベンズアミド含有組成物 |
DK2685986T3 (da) | 2011-03-18 | 2020-03-02 | Genzyme Corp | Glucosylceramidsyntasehæmmer |
MA37975B2 (fr) | 2012-09-11 | 2021-03-31 | Genzyme Corp | Inhibiteurs de synthase de glucosylcéramide |
AU2021215396A1 (en) | 2020-02-03 | 2022-09-29 | Genzyme Corporation | Methods for treating neurological symptoms associated with lysosomal storage diseases |
IL300090A (en) | 2020-07-24 | 2023-03-01 | Genzyme Corp | Pharmaceutical preparations containing VENGLUSTAT |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4207327A (en) * | 1977-08-19 | 1980-06-10 | A. H. Robins Company, Inc. | N-(4-Pyrazolidinyl)benzamides and their amino precursors |
EP0099194A3 (en) * | 1982-07-03 | 1984-04-11 | Beecham Group Plc | Novel benzamides |
EP0158265A2 (en) * | 1984-04-13 | 1985-10-16 | Beecham Group Plc | Benzamide and anilide derivatives |
CA1260474A (en) * | 1984-12-03 | 1989-09-26 | Raymond A. Stokbroekx | Benzoxazol- and benzothiazolamine derivatives |
GB8525913D0 (en) * | 1985-10-21 | 1985-11-27 | Beecham Group Plc | Compounds |
EP0498466B1 (en) * | 1985-04-27 | 2002-07-24 | F. Hoffmann-La Roche Ag | Indazole-3-carboxamide and -3-carboxylic acid derivatives |
GB8520616D0 (en) * | 1985-08-16 | 1985-09-25 | Beecham Group Plc | Compounds |
GB8525844D0 (en) * | 1985-10-19 | 1985-11-20 | Beecham Group Plc | Compounds |
EP0235878A3 (en) * | 1986-01-16 | 1989-06-14 | Beecham Group Plc | Novel compounds |
DE3785507T2 (de) * | 1986-07-31 | 1993-07-29 | Beecham Group Plc | Azabicyclische verbindungen, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung. |
-
1988
- 1988-12-08 AU AU26702/88A patent/AU611976B2/en not_active Ceased
- 1988-12-08 IE IE102988A patent/IE63474B1/en not_active IP Right Cessation
- 1988-12-08 IE IE366188A patent/IE62231B1/en not_active IP Right Cessation
- 1988-12-09 CA CA000585519A patent/CA1334095C/en not_active Expired - Fee Related
- 1988-12-09 IL IL88644A patent/IL88644A/xx not_active IP Right Cessation
- 1988-12-12 HU HU886399A patent/HU204267B/hu not_active IP Right Cessation
- 1988-12-14 DE DE3850255T patent/DE3850255T2/de not_active Expired - Fee Related
- 1988-12-14 ES ES88311802T patent/ES2051867T3/es not_active Expired - Lifetime
- 1988-12-14 AT AT88311802T patent/ATE67200T1/de not_active IP Right Cessation
- 1988-12-14 EP EP89202801A patent/EP0361629B1/en not_active Expired - Lifetime
- 1988-12-14 AT AT89202801T patent/ATE107304T1/de not_active IP Right Cessation
- 1988-12-14 EP EP88311802A patent/EP0323077B1/en not_active Expired - Lifetime
- 1988-12-14 GB GB8829164A patent/GB2213816B/en not_active Expired - Fee Related
- 1988-12-14 DE DE8888311802T patent/DE3864807D1/de not_active Expired - Fee Related
- 1988-12-14 ES ES89202801T patent/ES2053959T3/es not_active Expired - Lifetime
- 1988-12-20 DK DK710488A patent/DK710488A/da not_active Application Discontinuation
- 1988-12-21 PT PT89286A patent/PT89286B/pt not_active IP Right Cessation
- 1988-12-21 FI FI885917A patent/FI95031C/fi not_active IP Right Cessation
- 1988-12-22 KR KR1019880017218A patent/KR970009588B1/ko not_active IP Right Cessation
- 1988-12-22 JP JP63324701A patent/JP2588265B2/ja not_active Expired - Fee Related
- 1988-12-23 PH PH37977A patent/PH27437A/en unknown
-
1989
- 1989-10-16 US US07/421,920 patent/US4983600A/en not_active Expired - Lifetime
- 1989-12-19 US US07/453,000 patent/US5106843A/en not_active Expired - Lifetime
-
1991
- 1991-09-12 GR GR91401252T patent/GR3002701T3/el unknown
-
1993
- 1993-07-08 DK DK082793A patent/DK82793A/da not_active Application Discontinuation
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