DK65380A - Heterocycloske oxypropanolaminderivater fremgangsmaader til deres fremstilling og laegemidler indeholdende disse forbindelser - Google Patents

Heterocycloske oxypropanolaminderivater fremgangsmaader til deres fremstilling og laegemidler indeholdende disse forbindelser

Info

Publication number
DK65380A
DK65380A DK65380A DK65380A DK65380A DK 65380 A DK65380 A DK 65380A DK 65380 A DK65380 A DK 65380A DK 65380 A DK65380 A DK 65380A DK 65380 A DK65380 A DK 65380A
Authority
DK
Denmark
Prior art keywords
radical
radicals
lower alkyl
hydrogen atom
atom
Prior art date
Application number
DK65380A
Other languages
Danish (da)
English (en)
Inventor
W G Friebe
H Michel
C H Ross
F Wiedemann
W Bartsch
K Dietmann
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of DK65380A publication Critical patent/DK65380A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/26—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/16—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C07D249/18—Benzotriazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Indole Compounds (AREA)
DK65380A 1979-02-16 1980-02-15 Heterocycloske oxypropanolaminderivater fremgangsmaader til deres fremstilling og laegemidler indeholdende disse forbindelser DK65380A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19792905877 DE2905877A1 (de) 1979-02-16 1979-02-16 Neue aminopropanolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
DK65380A true DK65380A (da) 1980-08-17

Family

ID=6063044

Family Applications (1)

Application Number Title Priority Date Filing Date
DK65380A DK65380A (da) 1979-02-16 1980-02-15 Heterocycloske oxypropanolaminderivater fremgangsmaader til deres fremstilling og laegemidler indeholdende disse forbindelser

Country Status (17)

Country Link
US (1) US4346093A (enExample)
EP (1) EP0014951B1 (enExample)
JP (1) JPS55120559A (enExample)
AT (1) ATE2190T1 (enExample)
AU (1) AU531282B2 (enExample)
CA (1) CA1134827A (enExample)
CS (1) CS227305B2 (enExample)
DD (1) DD148774A5 (enExample)
DE (2) DE2905877A1 (enExample)
DK (1) DK65380A (enExample)
ES (1) ES488657A1 (enExample)
FI (1) FI66371C (enExample)
HK (1) HK4486A (enExample)
HU (1) HU184719B (enExample)
IL (1) IL59352A (enExample)
SU (1) SU1243622A3 (enExample)
ZA (1) ZA80894B (enExample)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD150456A5 (de) * 1979-03-01 1981-09-02 Ciba Geigy Ag Verfahren zur herstellung von derivaten des 3-amino-1,2-propandiols
SE8003277L (sv) 1979-05-04 1980-11-05 Continental Pharma Bensimidazolderivat, deras framstellning och anvendning samt kompositioner innehallande dessa derivat
EP0034116A3 (en) * 1980-02-11 1981-09-02 Berlex Laboratories, Inc. N-(3-phenoxy-2-hydroxypropyl)benzimidazole-1-alkanamines
DE3030047A1 (de) * 1980-08-08 1982-03-11 Boehringer Mannheim Gmbh, 6800 Mannheim Neue aminopropanol-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3029980A1 (de) * 1980-08-08 1982-03-11 Boehringer Mannheim Gmbh, 6800 Mannheim Indolderivate und verfahren zu ihrer herstellung
DE3131146A1 (de) * 1981-08-06 1983-02-24 Boehringer Mannheim Gmbh, 6800 Mannheim Neue heteroaryloxypropanolamine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
FR2523964B1 (fr) * 1982-03-23 1985-09-27 Sanofi Sa Nouveaux derives de la tryptamine actifs notamment sur le systeme cardiovasculaire et procede pour leur preparation
DE3310891A1 (de) * 1983-03-25 1984-09-27 Boehringer Mannheim Gmbh, 6800 Mannheim Neue indolinon-(2)-derivate, verfahren zu ihrer herstellung, diese verbindungen enthaltende arzneimittel und zwischenprodukte
US4562200A (en) * 1983-06-30 1985-12-31 American Home Products Corporation 5(Indolyl) and 5(2,3-dihydroindolyl) substituted aminoethanols and their use as anti-hypertensives
AU575153B2 (en) * 1984-04-09 1988-07-21 Du Pont Merck Pharmaceutical Company, The Pharmaceutical compositions and method for treatment for prophylaxis of cardiac disorders
DE3540149A1 (de) * 1985-11-13 1987-05-14 Boehringer Mannheim Gmbh Verwendung von 1-(benztriazol-4-yloxy)3-(2-(2-methoxyphenoxy) -ethylamino)-2-propanol als antiglaukommittel, optisch aktive r und s isomere dieser substanz, verfahren zur herstellung derselben sowie arzneimittel, die diese substanzen enthalten
US5081121A (en) * 1988-05-24 1992-01-14 Tatsushi Osawa 4(1h)-quinolone derivatives
AU642041B2 (en) * 1990-09-13 1993-10-07 Beecham Group Plc Indole ureas as 5 HT receptor antagonist
JPH09502166A (ja) * 1993-07-31 1997-03-04 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー アドレナリン受容体作動薬活性を有する２−ベンゾヘテロシクリルオキシまたはチオプロパノールアミン誘導体
US5576321A (en) * 1995-01-17 1996-11-19 Eli Lilly And Company Compounds having effects on serotonin-related systems
US5741789A (en) 1995-01-17 1998-04-21 Eli Lilly And Company Compounds having effects on serotonin-related systems
ZA967892B (en) * 1995-09-21 1998-03-18 Lilly Co Eli Selective β3 adrenergic agonists.
US6075040A (en) * 1996-09-05 2000-06-13 Eli Lilly And Company Selective β3 adrenergic agonists
ATE215369T1 (de) 1996-09-05 2002-04-15 Lilly Co Eli Carbazolanaloge als selektive beta3-adrenergische agonisten
FR2756286A1 (fr) * 1996-11-27 1998-05-29 Pf Medicament Amino alcools aromatiques, leur preparation et leurs applications comme medicaments
CO5011072A1 (es) * 1997-12-05 2001-02-28 Lilly Co Eli Etanolaminas pirazinil substituidas como agfonistas de los receptores
JP2003514801A (ja) * 1999-11-15 2003-04-22 イーライ・リリー・アンド・カンパニー 家畜の生産を改善するためのインダゾリルオキシプロパノールアミン
TW593278B (en) * 2001-01-23 2004-06-21 Wyeth Corp 1-aryl-or 1-alkylsulfonylbenzazole derivatives as 5-hydroxytryptamine-6 ligands
SE0102640D0 (sv) * 2001-07-31 2001-07-31 Astrazeneca Ab Novel compounds
MA44994A (fr) * 2016-05-13 2019-03-20 Univ Leland Stanford Junior Composés de modulation des récepteurs adrénergiques et leurs procédés d'utilisation
GB202213163D0 (en) * 2022-09-08 2022-10-26 Cambridge Entpr Ltd Novel compounds, compositions and therapeutic uses thereof

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE623749A (enExample) 1961-12-08
CH483423A (de) * 1967-05-29 1969-12-31 Sandoz Ag Verfahren zur Herstellung einer neuen Indolverbindung
US3699123A (en) * 1970-03-24 1972-10-17 Sandoz Ltd 4-(3-amino-2-hydroxy-propoxy) indole derivatives
CH532040A (de) * 1970-03-24 1972-12-31 Sandoz Ag Verfahren zur Herstellung neuer Indolderivate
US3751429A (en) * 1970-03-24 1973-08-07 Sandoz Ltd 4-(3-amino-2-substituted propoxy)indole derivatives
CH536839A (de) * 1970-03-24 1973-05-15 Sandoz Ag Verfahren zur Herstellung einer neuen Indolverbindung
SE379196B (enExample) 1971-06-24 1975-09-29 Sandoz Ag
DE2508251C2 (de) 1975-02-26 1983-12-29 Boehringer Mannheim Gmbh, 6800 Mannheim Derivate des Indols, Verfahren zu deren Herstellung sowie diese enthaltende Arzneimittel
US4189494A (en) * 1975-11-06 1980-02-19 Sandoz Ltd. Reducing free fatty acid of the blood and suppressing appetite
CH624395A5 (enExample) 1976-01-08 1981-07-31 Ciba Geigy Ag
DE2619164C2 (de) 1976-04-30 1985-07-11 Boehringer Mannheim Gmbh, 6800 Mannheim Indazolyl-(4)-oxy-propanolamine, Verfahren zu ihrer Herstellung und deren Verwendung
DE2626890A1 (de) 1976-06-16 1977-12-29 Boehringer Mannheim Gmbh Neue derivate des indols, verfahren zu deren herstellung sowie diese enthaltende arzneimittel
DE2651574A1 (de) 1976-11-12 1978-05-18 Boehringer Mannheim Gmbh Ein neues aminopropanol-derivat und verfahren zu dessen herstellung
NZ187066A (en) * 1977-05-03 1981-02-11 Hoffmann La Roche 4-(3-substitutedamino-2-hydroxypropoxy)-benzimidazolidin-2-(ones or thiones)
US4235919A (en) * 1977-07-21 1980-11-25 Sandoz Ltd. 1-(Indol-4-yloxy)-3-(2-substituted amino)-2-propanols and pharmaceutical use thereof
DE2830211A1 (de) * 1977-07-21 1979-02-01 Sandoz Ag Substituierte indol-derivate, ihre herstellung und verwendung
DE2801980A1 (de) * 1978-01-18 1979-07-19 Boehringer Mannheim Gmbh 4-hydroxy-2-benzimidazolin-thion- derivate, verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel
EP0003758A1 (de) * 1978-02-09 1979-09-05 Ciba-Geigy Ag Verätherte Hydroxy-benzodiheterocyclen und ihre Säureadditionssalze, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Präparate

Also Published As

Publication number Publication date
EP0014951A2 (de) 1980-09-03
ZA80894B (en) 1981-09-30
IL59352A0 (en) 1980-05-30
ATE2190T1 (de) 1983-01-15
SU1243622A3 (ru) 1986-07-07
FI66371C (fi) 1984-10-10
ES488657A1 (es) 1980-09-16
EP0014951B1 (de) 1983-01-12
DE3061555D1 (en) 1983-02-17
HU184719B (en) 1984-10-29
DD148774A5 (de) 1981-06-10
JPS55120559A (en) 1980-09-17
CS227305B2 (en) 1984-04-16
DE2905877A1 (de) 1980-08-28
IL59352A (en) 1985-01-31
FI66371B (fi) 1984-06-29
JPS6348864B2 (enExample) 1988-09-30
CA1134827A (en) 1982-11-02
HK4486A (en) 1986-01-31
AU5541080A (en) 1980-08-21
FI800408A7 (fi) 1980-08-17
US4346093A (en) 1982-08-24
EP0014951A3 (en) 1981-02-04
AU531282B2 (en) 1983-08-18

Similar Documents

Publication Publication Date Title
DK65380A (da) Heterocycloske oxypropanolaminderivater fremgangsmaader til deres fremstilling og laegemidler indeholdende disse forbindelser
NO831613L (no) Dihydropyridinderivater og fremgangsmaate for deres fremstilling.
HUP9901590A2 (hu) Szubsztituált aza- és diaza-cikloheptán- és -ciklooktán-származékok, alkalmazásuk, a vegyületeket tartalmazó gyógyászati készítmények
HUP0202593A2 (hu) Reverz transzkriptáz inhibitor hatású benzofenonok és ilyen vegyületeket tartalmazó gyógyászati készítmények
ES479932A1 (es) Un procedimiento para la preparacion de derivados de amino- piridina.
DK471586D0 (da) 3-vinyl- og 3-ethynyl-beta-carbolinderivater, deres fremstilling og deres anvendelse som laegemiddel
ATE21900T1 (de) Pyrimidinonderivate und diese enthaltende pharmazeutische zusammenstellungen.
NO812355L (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 3,1-benzoksazin-2-on-derivater
DK671588A (da) Bisphenylalkylpiperazinderivater og fremgangsmaade til fremstilling deraf
NO167746C (no) Analogifremgangsmaate til fremstilling av terapeutisk aktive muramylpeptidderivater.
ES2154453T3 (es) Compuestos pertenecientes a la familia de los amidiniums, composiciones farmaceuticas que les contienen y sus aplicaciones.
ES8402562A1 (es) Procedimiento para preparar derivados de guanidina.
DK160184D0 (da) Bis-(piperazinyl-eller homopiperazinyl)-alkaner og syreadditionssalte deraf,fremgangsmaade til deres fremstilling samt deres anvendelse
NO875318D0 (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive diazepinon-derivater.
SE8603589L (sv) Metylendioxifenantren- och stilbenderivat
DK610586D0 (da) 5-aminoalkyl-beta-carbolinderivater, deres fremstilling og deres anvendelse som laegemiddel
NZ335975A (en) Heterocyclic substituted pyrrolidine amide derivatives useful in treating respiratory diseases
DE3161640D1 (en) Propanol amine, derivatives, process for their preparation and medicines containing these compounds
ATE33134T1 (de) 2-aminoethyl-pyridin oder pyrazin-derivate, ihre herstellung und diese enthaltende pharmazeutische zusammensetzungen.
DK608586D0 (da) Polysubstituerede pyridin-1-oxider og fysiologisk aktive salte deraf, deres fremstilling og anvendelse som laegemidler
DK163922C (da) 2,3-dihydro-3-phenyl-2-benzofuranonderivater, fremgangsmaader til deres fremstilling og farmaceutiske midler indeholdende dem
DK523582A (da) Ketaler af 3'''-dehydro-kardenolid-tridigitoxosider, fremgangsmaade til deres fremstilling og deres anvendelse som laegemiddel
ATE121937T1 (de) Verwendung von 2h-1,2,4-benzothiadiazin-3(4h)- thion-1,1-dioxiden als antivirale arzneimittel.
PT100429A (pt) Uso de derivados da xantina na preparacao de um medicamento para inibicao da producao de factor de necrose tumoral
CA2149147A1 (en) Pharmacologically active pyrimidineamine derivatives and processes for the preparation thereof

Legal Events

Date Code Title Description
ARF Application refused