DK601985D0 - Fremgangsmaade til fremstilling af en bispecifik monoklonal antistof-determinant og proeve til maaling af maengden af et ukendt stof i en vaeskeproeve under anvendelse af en bispecifik monoklonal antistof-determinant - Google Patents

Fremgangsmaade til fremstilling af en bispecifik monoklonal antistof-determinant og proeve til maaling af maengden af et ukendt stof i en vaeskeproeve under anvendelse af en bispecifik monoklonal antistof-determinant

Info

Publication number
DK601985D0
DK601985D0 DK601985A DK601985A DK601985D0 DK 601985 D0 DK601985 D0 DK 601985D0 DK 601985 A DK601985 A DK 601985A DK 601985 A DK601985 A DK 601985A DK 601985 D0 DK601985 D0 DK 601985D0
Authority
DK
Denmark
Prior art keywords
monoclonal antibody
bispecific monoclonal
test
determinant
molecules
Prior art date
Application number
DK601985A
Other languages
English (en)
Other versions
DK601985A (da
DK169153B1 (da
Inventor
Henry P Paulus
Original Assignee
Boston Biomed Res Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boston Biomed Res Inst filed Critical Boston Biomed Res Inst
Publication of DK601985D0 publication Critical patent/DK601985D0/da
Publication of DK601985A publication Critical patent/DK601985A/da
Application granted granted Critical
Publication of DK169153B1 publication Critical patent/DK169153B1/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Steroid Compounds (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK601985A 1984-04-23 1985-12-23 Fremgangsmåde til fremstilling af en bispecifik monoklonal antistof-determinant DK169153B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US60312584A 1984-04-23 1984-04-23
US60312584 1984-04-23
US8500737 1985-04-22
PCT/US1985/000737 WO1985004811A1 (en) 1984-04-23 1985-04-22 Bispecific antibody determinants

Publications (3)

Publication Number Publication Date
DK601985D0 true DK601985D0 (da) 1985-12-23
DK601985A DK601985A (da) 1985-12-23
DK169153B1 DK169153B1 (da) 1994-08-29

Family

ID=24414191

Family Applications (1)

Application Number Title Priority Date Filing Date
DK601985A DK169153B1 (da) 1984-04-23 1985-12-23 Fremgangsmåde til fremstilling af en bispecifik monoklonal antistof-determinant

Country Status (11)

Country Link
EP (1) EP0179872B1 (da)
JP (1) JPH0617909B2 (da)
AT (1) ATE64622T1 (da)
AU (1) AU595159B2 (da)
CA (1) CA1338828C (da)
DE (1) DE3583278D1 (da)
DK (1) DK169153B1 (da)
FI (1) FI85946C (da)
IT (1) IT1183798B (da)
NO (1) NO166383C (da)
WO (1) WO1985004811A1 (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0252951A4 (en) * 1986-01-06 1988-09-07 Univ Melbourne TECHNETIUM-ANTIBODY CONJUGATES.
FR2604092B1 (fr) * 1986-09-19 1990-04-13 Immunotech Sa Immunoreactifs destines a cibler les cellules animales pour leur visualisation ou leur destruction in vivo
FR2608445B1 (fr) * 1986-12-19 1989-04-21 Muraour Renaud Embout pour manche de raquette de tennis et autres similaires, et raquette equipee de cet embout
EP0301333A3 (en) * 1987-07-29 1992-07-01 Abbott Laboratories Liposome based homogeneous immunoassay for diagnostic tests
US4971916A (en) * 1987-07-29 1990-11-20 Abbott Laboratories Liposome based homogeneous immunoassay for diagnostic tests
US5086002A (en) * 1987-09-07 1992-02-04 Agen Biomedical, Ltd. Erythrocyte agglutination assay
NZ226202A (en) * 1987-09-17 1992-01-29 Agen Ltd Erythrocyte agglutination assay
US6010902A (en) * 1988-04-04 2000-01-04 Bristol-Meyers Squibb Company Antibody heteroconjugates and bispecific antibodies for use in regulation of lymphocyte activity
FI105320B (fi) * 1988-04-04 2000-07-31 Oncogen Menetelmä vasta-aineheterokonjugaattien valmistamiseksi, joita käytetään imusoluaktiivisuuden säätelyssä ja diagnoosissa
SE8804074D0 (sv) * 1988-11-10 1988-11-10 Pharmacia Ab Sensorenhet och dess anvaendning i biosensorsystem
IT1235349B (it) * 1988-12-23 1992-06-30 Biodata Spa Saggio immunologico per determinazioni in fase omogenea
US5583003A (en) * 1989-09-25 1996-12-10 Agen Limited Agglutination assay
TW212184B (da) * 1990-04-02 1993-09-01 Takeda Pharm Industry Co Ltd
EP2064549B1 (en) * 2006-09-21 2012-10-24 Prometheus Laboratories, Inc. Antibody-based arrays for detecting multiple signal transducers in rare circulating cells

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4233402A (en) * 1978-04-05 1980-11-11 Syva Company Reagents and method employing channeling
AU531777B2 (en) * 1978-04-05 1983-09-08 Syva Co. Label/solid conjugate immunoassay system
US4474893A (en) * 1981-07-01 1984-10-02 The University of Texas System Cancer Center Recombinant monoclonal antibodies
US4433859A (en) * 1981-07-16 1984-02-28 Nl Industries, Inc. Wellhead connector with release mechanism
US4433059A (en) * 1981-09-08 1984-02-21 Ortho Diagnostic Systems Inc. Double antibody conjugate
US4520110A (en) * 1981-10-06 1985-05-28 The Board Of Trustees Of The Leland Stanford Junior University Fluorescent immunoassay employing a phycobiliprotein labeled ligand or receptor
CA1179942A (en) * 1981-10-06 1984-12-27 Lubert Stryer Fluorescent conjugates for analysis of molecules and cells
CA1213229A (en) * 1982-04-12 1986-10-28 Gary S. David Antibodies having dual specificities, their preparation and uses therefor
US4446233A (en) * 1982-05-05 1984-05-01 E. I. Du Pont De Nemours And Company Homogeneous immunoassay using covalent hybrid antibodies
US4470925A (en) * 1982-05-05 1984-09-11 E. I. Du Pont De Nemours And Company Immunoglobulin half-molecules and process for producing hybrid antibodies
CA1194415A (en) * 1982-05-05 1985-10-01 E. I. Du Pont De Nemours And Company Immunoglobulin half-molecules and process for producing hybrid antibodies

Also Published As

Publication number Publication date
WO1985004811A1 (en) 1985-11-07
FI85946C (fi) 1992-06-25
JPH0617909B2 (ja) 1994-03-09
AU595159B2 (en) 1990-03-29
DK601985A (da) 1985-12-23
CA1338828C (en) 1997-01-07
DE3583278D1 (de) 1991-07-25
NO166383B (no) 1991-04-02
FI855086L (fi) 1985-12-19
NO855200L (no) 1985-12-20
DK169153B1 (da) 1994-08-29
NO166383C (no) 1991-07-10
JPS61501418A (ja) 1986-07-10
IT8567383A0 (it) 1985-04-23
EP0179872B1 (en) 1991-06-19
FI855086A0 (fi) 1985-12-19
FI85946B (fi) 1992-03-13
EP0179872A1 (en) 1986-05-07
IT1183798B (it) 1987-10-22
EP0179872A4 (en) 1988-12-22
ATE64622T1 (de) 1991-07-15
IT8567383A1 (it) 1986-10-23
AU4290185A (en) 1985-11-15

Similar Documents

Publication Publication Date Title
DK601985D0 (da) Fremgangsmaade til fremstilling af en bispecifik monoklonal antistof-determinant og proeve til maaling af maengden af et ukendt stof i en vaeskeproeve under anvendelse af en bispecifik monoklonal antistof-determinant
US4366241B1 (da)
NO163255C (no) Homogen proeve av identiske bispesifikke antistoffdeterminanter for anvendelse i en enzymelektrode, samt elektrode-apparat for maaling.
DE3172347D1 (en) Method for producing an analytical antibody probe, an analytical antibody probe, and a method for analysing a sample for certain antibodies
ATE84879T1 (de) Verfahren zum erreichen einer linearen normkurve in einem sandwich-immunoassay.
IL51636A (en) Method and apparatus for analysing the concentration of antigen or antibody by radioimmunoassay
DK0681590T3 (da) Antikoagulerende sammensætning
KR850002385A (ko) PIVKA-Ⅱ의 측정(assay)용 방법 및 시약
DK311483D0 (da) Fremgangsmade til pavisning af tilstedevaerelsen af et antigen eller antistof i en proevevaeske og proevesaet til udfoerelse af fremgangsmaden
DE69018968D1 (de) BLUTGERINNUNGSFAKTOR BETA XIIa MONOKLONALE ANTIKÖRPER UND IMMUNANALYSE.
NO930705L (no) Fremgangsmaate for bestemmelse av en vannbehandlingspolymer i en vandig proeve
SE7714034L (sv) Forfarande for enzymkopplad immunoanalys
DK98692A (da) Monoklonalt antistof og fremgangsmaade til fremstilling deraf, hybridoma, som producerer det monoklonale antistof, og proeve for tumorcellefoelsomhed under anvendelse af det monoklonale antistof
PL195632A1 (pl) Sposob wytwarzania antygenu,sposob przygotowania odczynnika antygenowego oraz zestaw do wykonywania testu
ES2042661T3 (es) Procedimiento de determinacion inmunologico para la determinacion de sustancias libres que poseen propiedades hapteno.
DK157714C (da) Fremgangsmaade til bestemmelse af hepatitis a antigen, hepatitis a antigen/antistof-radionuclid og diagnostisk proeveudstyr
NO861554L (no) Anti-urokinasemonoklonalt antistoff, matrise inneholdende dette, testmetode og biokjemisk testutstyr som anvender det.
JPS5548638A (en) Photoacoustic analysis method
BR9105983A (pt) Anticorpos monoclonais que diferenciam entre proteinas de sequencias nativa e modificada
DK0472498T3 (da) Monoklone antistoffer mod Leptosphaeria.
JPS5218815A (en) Novel method of immunological clinical diagnosis by means of gel-preci pitation
KR850003169A (ko) 염기성 태아단백질의 측정방법 및 시약
JPS5596457A (en) Method of measuring quantity of opsonic surfaceelinked alpha22glycoprotein
FI813796A7 (fi) Immunoanalyysimenetelmä ja laite komponenttien kuten antigeenien tai vasta-aineiden määrittämiseksi.
FR2441847A1 (fr) Procede pour la detection quantitative et qualitative des antigenes, anticorps et haptenes

Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed