DK601985A - Fremgangsmaade til fremstilling af en bispecifik monoklonal antistof-determinant og proeve til maaling af maengden af et ukendt stof i en vaeskeproeve under anvendelse af en bispecifik monoklonal antistof-determinant - Google Patents

Fremgangsmaade til fremstilling af en bispecifik monoklonal antistof-determinant og proeve til maaling af maengden af et ukendt stof i en vaeskeproeve under anvendelse af en bispecifik monoklonal antistof-determinant Download PDF

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Publication number
DK601985A
DK601985A DK601985A DK601985A DK601985A DK 601985 A DK601985 A DK 601985A DK 601985 A DK601985 A DK 601985A DK 601985 A DK601985 A DK 601985A DK 601985 A DK601985 A DK 601985A
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Prior art keywords
monoclonal antibody
bispecific monoclonal
test
determinant
preparing
Prior art date
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DK601985A
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English (en)
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DK601985D0 (da
DK169153B1 (da
Inventor
Henry P Paulus
Original Assignee
Boston Biomed Res Inst
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Application filed by Boston Biomed Res Inst filed Critical Boston Biomed Res Inst
Publication of DK601985A publication Critical patent/DK601985A/da
Publication of DK601985D0 publication Critical patent/DK601985D0/da
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Publication of DK169153B1 publication Critical patent/DK169153B1/da

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK601985A 1984-04-23 1985-12-23 Fremgangsmåde til fremstilling af en bispecifik monoklonal antistof-determinant DK169153B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US60312584A 1984-04-23 1984-04-23
US60312584 1984-04-23
US8500737 1985-04-22
PCT/US1985/000737 WO1985004811A1 (en) 1984-04-23 1985-04-22 Bispecific antibody determinants

Publications (3)

Publication Number Publication Date
DK601985A true DK601985A (da) 1985-12-23
DK601985D0 DK601985D0 (da) 1985-12-23
DK169153B1 DK169153B1 (da) 1994-08-29

Family

ID=24414191

Family Applications (1)

Application Number Title Priority Date Filing Date
DK601985A DK169153B1 (da) 1984-04-23 1985-12-23 Fremgangsmåde til fremstilling af en bispecifik monoklonal antistof-determinant

Country Status (11)

Country Link
EP (1) EP0179872B1 (da)
JP (1) JPH0617909B2 (da)
AT (1) ATE64622T1 (da)
AU (1) AU595159B2 (da)
CA (1) CA1338828C (da)
DE (1) DE3583278D1 (da)
DK (1) DK169153B1 (da)
FI (1) FI85946C (da)
IT (1) IT1183798B (da)
NO (1) NO166383C (da)
WO (1) WO1985004811A1 (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0252951A4 (en) * 1986-01-06 1988-09-07 Univ Melbourne TECHNETIUM-ANTIBODY CONJUGATES.
FR2604092B1 (fr) * 1986-09-19 1990-04-13 Immunotech Sa Immunoreactifs destines a cibler les cellules animales pour leur visualisation ou leur destruction in vivo
FR2608445B1 (fr) * 1986-12-19 1989-04-21 Muraour Renaud Embout pour manche de raquette de tennis et autres similaires, et raquette equipee de cet embout
EP0301333A3 (en) * 1987-07-29 1992-07-01 Abbott Laboratories Liposome based homogeneous immunoassay for diagnostic tests
US4971916A (en) * 1987-07-29 1990-11-20 Abbott Laboratories Liposome based homogeneous immunoassay for diagnostic tests
US5086002A (en) * 1987-09-07 1992-02-04 Agen Biomedical, Ltd. Erythrocyte agglutination assay
IL87768A (en) * 1987-09-17 1994-12-29 Agen Ltd Blood assay including erythrocyte agglutination and reagent for the assay comprising conjugate of erythrocyte binding molecule and analyte binding molecule
US6010902A (en) * 1988-04-04 2000-01-04 Bristol-Meyers Squibb Company Antibody heteroconjugates and bispecific antibodies for use in regulation of lymphocyte activity
FI105320B (fi) * 1988-04-04 2000-07-31 Oncogen Menetelmä vasta-aineheterokonjugaattien valmistamiseksi, joita käytetään imusoluaktiivisuuden säätelyssä ja diagnoosissa
SE8804074D0 (sv) * 1988-11-10 1988-11-10 Pharmacia Ab Sensorenhet och dess anvaendning i biosensorsystem
IT1235349B (it) * 1988-12-23 1992-06-30 Biodata Spa Saggio immunologico per determinazioni in fase omogenea
US5583003A (en) * 1989-09-25 1996-12-10 Agen Limited Agglutination assay
TW212184B (da) * 1990-04-02 1993-09-01 Takeda Pharm Industry Co Ltd
KR101485303B1 (ko) * 2006-09-21 2015-01-22 네스텍 소시에테아노님 희귀 순환세포 내의 다수의 신호전달인자를 검출하기 위한 항체 기반 분석법

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4233402A (en) * 1978-04-05 1980-11-11 Syva Company Reagents and method employing channeling
AU531777B2 (en) * 1978-04-05 1983-09-08 Syva Co. Label/solid conjugate immunoassay system
US4474893A (en) * 1981-07-01 1984-10-02 The University of Texas System Cancer Center Recombinant monoclonal antibodies
US4433859A (en) * 1981-07-16 1984-02-28 Nl Industries, Inc. Wellhead connector with release mechanism
US4433059A (en) * 1981-09-08 1984-02-21 Ortho Diagnostic Systems Inc. Double antibody conjugate
US4520110A (en) * 1981-10-06 1985-05-28 The Board Of Trustees Of The Leland Stanford Junior University Fluorescent immunoassay employing a phycobiliprotein labeled ligand or receptor
CA1179942A (en) * 1981-10-06 1984-12-27 Lubert Stryer Fluorescent conjugates for analysis of molecules and cells
CA1213229A (en) * 1982-04-12 1986-10-28 Gary S. David Antibodies having dual specificities, their preparation and uses therefor
CA1194415A (en) * 1982-05-05 1985-10-01 E. I. Du Pont De Nemours And Company Immunoglobulin half-molecules and process for producing hybrid antibodies
US4470925A (en) * 1982-05-05 1984-09-11 E. I. Du Pont De Nemours And Company Immunoglobulin half-molecules and process for producing hybrid antibodies
US4446233A (en) * 1982-05-05 1984-05-01 E. I. Du Pont De Nemours And Company Homogeneous immunoassay using covalent hybrid antibodies

Also Published As

Publication number Publication date
NO166383B (no) 1991-04-02
IT8567383A0 (it) 1985-04-23
FI85946B (fi) 1992-03-13
AU4290185A (en) 1985-11-15
JPS61501418A (ja) 1986-07-10
DE3583278D1 (de) 1991-07-25
CA1338828C (en) 1997-01-07
AU595159B2 (en) 1990-03-29
WO1985004811A1 (en) 1985-11-07
IT1183798B (it) 1987-10-22
DK601985D0 (da) 1985-12-23
EP0179872A1 (en) 1986-05-07
FI855086A (fi) 1985-12-19
JPH0617909B2 (ja) 1994-03-09
DK169153B1 (da) 1994-08-29
ATE64622T1 (de) 1991-07-15
IT8567383A1 (it) 1986-10-23
NO855200L (no) 1985-12-20
FI855086A0 (fi) 1985-12-19
EP0179872B1 (en) 1991-06-19
FI85946C (fi) 1992-06-25
EP0179872A4 (en) 1988-12-22
NO166383C (no) 1991-07-10

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Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed