NO166383C - Fremgangsmaate ved fremstilling av bispesifikke antistoff-determinanter. - Google Patents

Fremgangsmaate ved fremstilling av bispesifikke antistoff-determinanter.

Info

Publication number
NO166383C
NO166383C NO85855200A NO855200A NO166383C NO 166383 C NO166383 C NO 166383C NO 85855200 A NO85855200 A NO 85855200A NO 855200 A NO855200 A NO 855200A NO 166383 C NO166383 C NO 166383C
Authority
NO
Norway
Prior art keywords
molecules
antibody determinants
determinant
bispecific antibody
procedure
Prior art date
Application number
NO85855200A
Other languages
English (en)
Other versions
NO166383B (no
NO855200L (no
Inventor
Henry P Paulus
Original Assignee
Boston Biomed Res Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boston Biomed Res Inst filed Critical Boston Biomed Res Inst
Publication of NO855200L publication Critical patent/NO855200L/no
Publication of NO166383B publication Critical patent/NO166383B/no
Publication of NO166383C publication Critical patent/NO166383C/no

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Steroid Compounds (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO85855200A 1984-04-23 1985-12-20 Fremgangsmaate ved fremstilling av bispesifikke antistoff-determinanter. NO166383C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60312584A 1984-04-23 1984-04-23
PCT/US1985/000737 WO1985004811A1 (en) 1984-04-23 1985-04-22 Bispecific antibody determinants

Publications (3)

Publication Number Publication Date
NO855200L NO855200L (no) 1985-12-20
NO166383B NO166383B (no) 1991-04-02
NO166383C true NO166383C (no) 1991-07-10

Family

ID=24414191

Family Applications (1)

Application Number Title Priority Date Filing Date
NO85855200A NO166383C (no) 1984-04-23 1985-12-20 Fremgangsmaate ved fremstilling av bispesifikke antistoff-determinanter.

Country Status (11)

Country Link
EP (1) EP0179872B1 (no)
JP (1) JPH0617909B2 (no)
AT (1) ATE64622T1 (no)
AU (1) AU595159B2 (no)
CA (1) CA1338828C (no)
DE (1) DE3583278D1 (no)
DK (1) DK169153B1 (no)
FI (1) FI85946C (no)
IT (1) IT1183798B (no)
NO (1) NO166383C (no)
WO (1) WO1985004811A1 (no)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0252951A4 (en) * 1986-01-06 1988-09-07 Univ Melbourne TECHNETIUM-ANTIBODY CONJUGATES.
FR2604092B1 (fr) * 1986-09-19 1990-04-13 Immunotech Sa Immunoreactifs destines a cibler les cellules animales pour leur visualisation ou leur destruction in vivo
FR2608445B1 (fr) * 1986-12-19 1989-04-21 Muraour Renaud Embout pour manche de raquette de tennis et autres similaires, et raquette equipee de cet embout
EP0301333A3 (en) * 1987-07-29 1992-07-01 Abbott Laboratories Liposome based homogeneous immunoassay for diagnostic tests
US4971916A (en) * 1987-07-29 1990-11-20 Abbott Laboratories Liposome based homogeneous immunoassay for diagnostic tests
US5086002A (en) * 1987-09-07 1992-02-04 Agen Biomedical, Ltd. Erythrocyte agglutination assay
NZ226202A (en) * 1987-09-17 1992-01-29 Agen Ltd Erythrocyte agglutination assay
US6010902A (en) * 1988-04-04 2000-01-04 Bristol-Meyers Squibb Company Antibody heteroconjugates and bispecific antibodies for use in regulation of lymphocyte activity
FI105320B (fi) * 1988-04-04 2000-07-31 Oncogen Menetelmä vasta-aineheterokonjugaattien valmistamiseksi, joita käytetään imusoluaktiivisuuden säätelyssä ja diagnoosissa
SE8804074D0 (sv) * 1988-11-10 1988-11-10 Pharmacia Ab Sensorenhet och dess anvaendning i biosensorsystem
IT1235349B (it) * 1988-12-23 1992-06-30 Biodata Spa Saggio immunologico per determinazioni in fase omogenea
US5583003A (en) * 1989-09-25 1996-12-10 Agen Limited Agglutination assay
TW212184B (no) * 1990-04-02 1993-09-01 Takeda Pharm Industry Co Ltd
EP2064549B1 (en) * 2006-09-21 2012-10-24 Prometheus Laboratories, Inc. Antibody-based arrays for detecting multiple signal transducers in rare circulating cells

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4233402A (en) * 1978-04-05 1980-11-11 Syva Company Reagents and method employing channeling
AU531777B2 (en) * 1978-04-05 1983-09-08 Syva Co. Label/solid conjugate immunoassay system
US4474893A (en) * 1981-07-01 1984-10-02 The University of Texas System Cancer Center Recombinant monoclonal antibodies
US4433859A (en) * 1981-07-16 1984-02-28 Nl Industries, Inc. Wellhead connector with release mechanism
US4433059A (en) * 1981-09-08 1984-02-21 Ortho Diagnostic Systems Inc. Double antibody conjugate
US4520110A (en) * 1981-10-06 1985-05-28 The Board Of Trustees Of The Leland Stanford Junior University Fluorescent immunoassay employing a phycobiliprotein labeled ligand or receptor
CA1179942A (en) * 1981-10-06 1984-12-27 Lubert Stryer Fluorescent conjugates for analysis of molecules and cells
CA1213229A (en) * 1982-04-12 1986-10-28 Gary S. David Antibodies having dual specificities, their preparation and uses therefor
US4446233A (en) * 1982-05-05 1984-05-01 E. I. Du Pont De Nemours And Company Homogeneous immunoassay using covalent hybrid antibodies
US4470925A (en) * 1982-05-05 1984-09-11 E. I. Du Pont De Nemours And Company Immunoglobulin half-molecules and process for producing hybrid antibodies
CA1194415A (en) * 1982-05-05 1985-10-01 E. I. Du Pont De Nemours And Company Immunoglobulin half-molecules and process for producing hybrid antibodies

Also Published As

Publication number Publication date
WO1985004811A1 (en) 1985-11-07
FI85946C (fi) 1992-06-25
DK601985D0 (da) 1985-12-23
JPH0617909B2 (ja) 1994-03-09
AU595159B2 (en) 1990-03-29
DK601985A (da) 1985-12-23
CA1338828C (en) 1997-01-07
DE3583278D1 (de) 1991-07-25
NO166383B (no) 1991-04-02
FI855086L (fi) 1985-12-19
NO855200L (no) 1985-12-20
DK169153B1 (da) 1994-08-29
JPS61501418A (ja) 1986-07-10
IT8567383A0 (it) 1985-04-23
EP0179872B1 (en) 1991-06-19
FI855086A0 (fi) 1985-12-19
FI85946B (fi) 1992-03-13
EP0179872A1 (en) 1986-05-07
IT1183798B (it) 1987-10-22
EP0179872A4 (en) 1988-12-22
ATE64622T1 (de) 1991-07-15
IT8567383A1 (it) 1986-10-23
AU4290185A (en) 1985-11-15

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