DK47285A - Renininhiberende peptider og anvendelsen deraf - Google Patents

Renininhiberende peptider og anvendelsen deraf Download PDF

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Publication number
DK47285A
DK47285A DK47285A DK47285A DK47285A DK 47285 A DK47285 A DK 47285A DK 47285 A DK47285 A DK 47285A DK 47285 A DK47285 A DK 47285A DK 47285 A DK47285 A DK 47285A
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DK
Denmark
Prior art keywords
pure
inhibiting peptides
peptides
inhibiting
Prior art date
Application number
DK47285A
Other languages
Danish (da)
English (en)
Other versions
DK47285D0 (da
Inventor
Rei Matsueda
Yuichiro Yabe
Mitsuo Yamazaki
Tatsuo Kokubu
Kunio Hiwada
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of DK47285D0 publication Critical patent/DK47285D0/da
Publication of DK47285A publication Critical patent/DK47285A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • C07F9/301—Acyclic saturated acids which can have further substituents on alkyl
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/86—Renin inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK47285A 1984-02-03 1985-02-01 Renininhiberende peptider og anvendelsen deraf DK47285A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP59019100A JPS60163899A (ja) 1984-02-03 1984-02-03 レニン阻害ペプチド類

Publications (2)

Publication Number Publication Date
DK47285D0 DK47285D0 (da) 1985-02-01
DK47285A true DK47285A (da) 1985-08-04

Family

ID=11990054

Family Applications (1)

Application Number Title Priority Date Filing Date
DK47285A DK47285A (da) 1984-02-03 1985-02-01 Renininhiberende peptider og anvendelsen deraf

Country Status (12)

Country Link
US (1) US4698329A (de)
EP (1) EP0152255A3 (de)
JP (1) JPS60163899A (de)
KR (1) KR910007576B1 (de)
CA (1) CA1267498A (de)
DK (1) DK47285A (de)
ES (1) ES8706167A1 (de)
FI (1) FI850429L (de)
HU (1) HU198951B (de)
NO (1) NO167744C (de)
PT (1) PT79917B (de)
SU (1) SU1739852A3 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4613676A (en) * 1983-11-23 1986-09-23 Ciba-Geigy Corporation Substituted 5-amino-4-hydroxyvaleryl derivatives
EP0181110A3 (de) * 1984-10-22 1988-05-11 Kissei Pharmaceutical Co. Ltd. Histidinderivate als Renininhibitoren
US4727060A (en) * 1984-11-13 1988-02-23 Ciba-Geigy Corporation Novel 5-amino-4-hydroxyvaleryl derivatives
EP0184855A3 (de) * 1984-12-14 1989-05-03 Abbott Laboratories Reninhemmende Verbindungen
EP0190891A3 (de) * 1985-01-31 1988-04-20 Kissei Pharmaceutical Co. Ltd. Aminosäurederivate
EP0206807A3 (de) * 1985-06-28 1988-01-20 Kissei Pharmaceutical Co. Ltd. Aminosäure-Derivate
US4853463A (en) * 1985-09-04 1989-08-01 Kissei Pharmaceutical Co., Ltd. Amino acid derivatives
US4894437A (en) * 1985-11-15 1990-01-16 The Upjohn Company Novel renin inhibiting polypeptide analogs containing S-aryl-D- or L- or DL-cysteinyl, 3-(arylthio)lactic acid or 3-(arylthio)alkyl moieties
KR870005013A (ko) * 1985-11-29 1987-06-04 가와무라 요시부미 레닌-억제 올리고펩티드, 그의 제조방법 및 용도
US4885292A (en) * 1986-02-03 1989-12-05 E. R. Squibb & Sons, Inc. N-heterocyclic alcohol renin inhibitors
FI870474A (fi) * 1986-02-07 1987-08-08 Ciba Geigy Ag Med svavelhaltiga grupper substituerade 5-amino-4-hydroxivalerylderivat.
US4727062A (en) * 1986-03-17 1988-02-23 Merck & Co., Inc. 3-Halovinylglycine antibacterial agents
JPS6322081A (ja) * 1986-07-11 1988-01-29 Kissei Pharmaceut Co Ltd 新規なアミノ酸誘導体
DE3627877A1 (de) * 1986-07-30 1988-02-04 Hoechst Ag Renin-hemmende di- und tripeptide, verfahren zu deren herstellung, diese enthaltende mittel und ihre verwendung
US4814342A (en) * 1986-10-31 1989-03-21 Pfizer Inc. Nor-statine and nor-cyclostatine polypeptides
DE3640535A1 (de) * 1986-11-27 1988-06-01 Merck Patent Gmbh Peptide
ZW23187A1 (en) * 1986-12-15 1988-06-29 Hoffmann La Roche Phosphinic acid derivatives
ES2062988T3 (es) * 1986-12-19 1995-01-01 Sankyo Co Nuevos oligopeptidos inhibidores de la renina, su preparacion y su uso.
US5032577A (en) * 1986-12-31 1991-07-16 Abbott Laboratories Peptidylaminodiols
NL8800100A (nl) * 1987-01-21 1988-08-16 Sandoz Ag Nieuwe peptidederivaten en werkwijzen voor het bereiden en toepassen van deze derivaten.
US4758584A (en) * 1987-02-05 1988-07-19 Ciba-Geigy Corporation Antihypertensive 5-amino-4-hydroxyvaleryl derivatives substituted by sulphur-containing groups
GB8707412D0 (en) * 1987-03-27 1987-04-29 Fujisawa Pharmaceutical Co Peptide compounds
US4921855A (en) * 1987-06-22 1990-05-01 Fujisawa Pharmaceutical Co., Ltd. New Histidyl amino acid derivatives, and pharmaceutical composition comprising the same
US4859654A (en) * 1987-07-01 1989-08-22 Pfizer Inc. Homocyclostatine and cyclostatine containing polypeptides as antihypertensive agents
DE68916271T2 (de) * 1988-01-26 1995-02-23 Sankyo Co Renin inhibierende Polypeptide, ihre Herstellung und Anwendung.
JPH0819153B2 (ja) * 1988-10-04 1996-02-28 キッセイ薬品工業株式会社 ペプチド誘導体
ES2077021T3 (es) * 1989-02-16 1995-11-16 Sankyo Co Peptidos que tienen actividad inhibidora de renina, su preparacion y uso.

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO812612L (no) * 1980-08-06 1982-02-08 Ferring Pharma Ltd Enzym-inhibitorer.
CA1245217A (en) * 1981-12-10 1988-11-22 Joshua S. Boger Renin inhibitory peptides having phe su13 xx deletion
EP0104041B1 (de) * 1982-09-15 1988-07-27 Aktiebolaget Hässle Enzyminhibitoren
AU573735B2 (en) * 1983-02-07 1988-06-23 Aktiebolaget Hassle Peptide analogue enzyme inhibitors
JPS59227851A (ja) * 1983-06-09 1984-12-21 Sankyo Co Ltd レニン阻害作用を有するペプチド類
US4613676A (en) * 1983-11-23 1986-09-23 Ciba-Geigy Corporation Substituted 5-amino-4-hydroxyvaleryl derivatives
CA1254699A (en) * 1984-03-12 1989-05-23 Jasjit S. Bindra Renin inhibitors containing statine or derivatives thereof
EP0163237A3 (de) * 1984-05-29 1988-04-27 Merck & Co. Inc. Di- und tripeptidale Renin-Hemmungsstoffe
EP0173481A3 (de) * 1984-08-06 1988-12-21 The Upjohn Company Peptide
SU1676454A3 (ru) * 1984-11-30 1991-09-07 Санкио Компани Лимитед (Фирма) Способ получени пептидов или их фармацевтически приемлемых солей

Also Published As

Publication number Publication date
ES8706167A1 (es) 1987-06-01
HUT38105A (en) 1986-04-28
PT79917B (en) 1987-02-05
HU198951B (en) 1989-12-28
NO850397L (no) 1985-08-05
PT79917A (en) 1985-03-01
JPS60163899A (ja) 1985-08-26
KR850006008A (ko) 1985-09-28
EP0152255A2 (de) 1985-08-21
FI850429A0 (fi) 1985-02-01
NO167744C (no) 1991-12-04
US4698329A (en) 1987-10-06
CA1267498A (en) 1990-04-03
DK47285D0 (da) 1985-02-01
NO167744B (no) 1991-08-26
EP0152255A3 (de) 1987-06-16
ES540110A0 (es) 1987-06-01
FI850429L (fi) 1985-08-04
KR910007576B1 (ko) 1991-09-28
SU1739852A3 (ru) 1992-06-07

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