NO167744C - Analogifremgangsmaate til fremstilling av renininhiberendepeptider. - Google Patents

Analogifremgangsmaate til fremstilling av renininhiberendepeptider.

Info

Publication number
NO167744C
NO167744C NO850397A NO850397A NO167744C NO 167744 C NO167744 C NO 167744C NO 850397 A NO850397 A NO 850397A NO 850397 A NO850397 A NO 850397A NO 167744 C NO167744 C NO 167744C
Authority
NO
Norway
Prior art keywords
preparation
inhibitor peptides
analogy procedure
pure inhibitor
pure
Prior art date
Application number
NO850397A
Other languages
English (en)
Other versions
NO850397L (no
NO167744B (no
Inventor
Rei Matsueda
Yuichiro Yabe
Mitsuo Yamazaki
Tatsuo Kokuba
Kunio Hiwada
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of NO850397L publication Critical patent/NO850397L/no
Publication of NO167744B publication Critical patent/NO167744B/no
Publication of NO167744C publication Critical patent/NO167744C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • C07F9/301—Acyclic saturated acids which can have further substituents on alkyl
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/86—Renin inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO850397A 1984-02-03 1985-02-01 Analogifremgangsmaate til fremstilling av renininhiberendepeptider. NO167744C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP59019100A JPS60163899A (ja) 1984-02-03 1984-02-03 レニン阻害ペプチド類

Publications (3)

Publication Number Publication Date
NO850397L NO850397L (no) 1985-08-05
NO167744B NO167744B (no) 1991-08-26
NO167744C true NO167744C (no) 1991-12-04

Family

ID=11990054

Family Applications (1)

Application Number Title Priority Date Filing Date
NO850397A NO167744C (no) 1984-02-03 1985-02-01 Analogifremgangsmaate til fremstilling av renininhiberendepeptider.

Country Status (12)

Country Link
US (1) US4698329A (no)
EP (1) EP0152255A3 (no)
JP (1) JPS60163899A (no)
KR (1) KR910007576B1 (no)
CA (1) CA1267498A (no)
DK (1) DK47285A (no)
ES (1) ES8706167A1 (no)
FI (1) FI850429L (no)
HU (1) HU198951B (no)
NO (1) NO167744C (no)
PT (1) PT79917B (no)
SU (1) SU1739852A3 (no)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4613676A (en) * 1983-11-23 1986-09-23 Ciba-Geigy Corporation Substituted 5-amino-4-hydroxyvaleryl derivatives
EP0181110A3 (en) * 1984-10-22 1988-05-11 Kissei Pharmaceutical Co. Ltd. Histidine derivatives as renin inhibitors
US4727060A (en) * 1984-11-13 1988-02-23 Ciba-Geigy Corporation Novel 5-amino-4-hydroxyvaleryl derivatives
EP0184855A3 (en) * 1984-12-14 1989-05-03 Abbott Laboratories Resin inhibiting compounds
EP0190891A3 (en) * 1985-01-31 1988-04-20 Kissei Pharmaceutical Co. Ltd. Novel amino acid derivatives
EP0206807A3 (en) * 1985-06-28 1988-01-20 Kissei Pharmaceutical Co. Ltd. Novel amino acid derivatives
US4853463A (en) * 1985-09-04 1989-08-01 Kissei Pharmaceutical Co., Ltd. Amino acid derivatives
US4894437A (en) * 1985-11-15 1990-01-16 The Upjohn Company Novel renin inhibiting polypeptide analogs containing S-aryl-D- or L- or DL-cysteinyl, 3-(arylthio)lactic acid or 3-(arylthio)alkyl moieties
KR870005013A (ko) * 1985-11-29 1987-06-04 가와무라 요시부미 레닌-억제 올리고펩티드, 그의 제조방법 및 용도
US4885292A (en) * 1986-02-03 1989-12-05 E. R. Squibb & Sons, Inc. N-heterocyclic alcohol renin inhibitors
EP0236734A3 (de) * 1986-02-07 1988-05-11 Ciba-Geigy Ag Durch schwefelhaltigen Gruppen substituierte 5-Amino-4-hydroxyvalerylderivate
US4727062A (en) * 1986-03-17 1988-02-23 Merck & Co., Inc. 3-Halovinylglycine antibacterial agents
JPS6322081A (ja) * 1986-07-11 1988-01-29 Kissei Pharmaceut Co Ltd 新規なアミノ酸誘導体
DE3627877A1 (de) * 1986-07-30 1988-02-04 Hoechst Ag Renin-hemmende di- und tripeptide, verfahren zu deren herstellung, diese enthaltende mittel und ihre verwendung
US4814342A (en) * 1986-10-31 1989-03-21 Pfizer Inc. Nor-statine and nor-cyclostatine polypeptides
DE3640535A1 (de) * 1986-11-27 1988-06-01 Merck Patent Gmbh Peptide
ZW23187A1 (en) * 1986-12-15 1988-06-29 Hoffmann La Roche Phosphinic acid derivatives
DE3789101T2 (de) * 1986-12-19 1994-07-21 Sankyo Co Renin inhibierende Oligopeptide, ihre Präparation und ihre Anwendung.
US5032577A (en) * 1986-12-31 1991-07-16 Abbott Laboratories Peptidylaminodiols
CH676988A5 (no) * 1987-01-21 1991-03-28 Sandoz Ag
US4758584A (en) * 1987-02-05 1988-07-19 Ciba-Geigy Corporation Antihypertensive 5-amino-4-hydroxyvaleryl derivatives substituted by sulphur-containing groups
GB8707412D0 (en) * 1987-03-27 1987-04-29 Fujisawa Pharmaceutical Co Peptide compounds
US4921855A (en) * 1987-06-22 1990-05-01 Fujisawa Pharmaceutical Co., Ltd. New Histidyl amino acid derivatives, and pharmaceutical composition comprising the same
US4859654A (en) * 1987-07-01 1989-08-22 Pfizer Inc. Homocyclostatine and cyclostatine containing polypeptides as antihypertensive agents
ES2058489T3 (es) * 1988-01-26 1994-11-01 Sankyo Co Oligopeptidos con actividades inhibidoras de la renina, su preparacion y su uso.
JPH0819153B2 (ja) * 1988-10-04 1996-02-28 キッセイ薬品工業株式会社 ペプチド誘導体
IE70080B1 (en) * 1989-02-16 1996-10-30 Sankyo Co Peptides having renin inhibitory activity their preparation and use

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO812612L (no) * 1980-08-06 1982-02-08 Ferring Pharma Ltd Enzym-inhibitorer.
CA1245217A (en) * 1981-12-10 1988-11-22 Joshua S. Boger Renin inhibitory peptides having phe su13 xx deletion
DE3377497D1 (en) * 1982-09-15 1988-09-01 Haessle Ab Enzyme inhibitors
AU573735B2 (en) * 1983-02-07 1988-06-23 Aktiebolaget Hassle Peptide analogue enzyme inhibitors
JPS59227851A (ja) * 1983-06-09 1984-12-21 Sankyo Co Ltd レニン阻害作用を有するペプチド類
US4613676A (en) * 1983-11-23 1986-09-23 Ciba-Geigy Corporation Substituted 5-amino-4-hydroxyvaleryl derivatives
DK110285A (da) * 1984-03-12 1985-09-13 Pfizer Polypeptider og polypeptidderivater indeholdende statin eller derivater deraf og farmaceutiske praeparater
EP0163237A3 (en) * 1984-05-29 1988-04-27 Merck & Co. Inc. Di- and tri-peptidal renin inhibitors
EP0486478A3 (en) * 1984-08-06 1992-08-12 The Upjohn Company Renin-inhibiting peptides
SU1676454A3 (ru) * 1984-11-30 1991-09-07 Санкио Компани Лимитед (Фирма) Способ получени пептидов или их фармацевтически приемлемых солей

Also Published As

Publication number Publication date
SU1739852A3 (ru) 1992-06-07
ES540110A0 (es) 1987-06-01
CA1267498A (en) 1990-04-03
ES8706167A1 (es) 1987-06-01
KR850006008A (ko) 1985-09-28
PT79917A (en) 1985-03-01
FI850429A0 (fi) 1985-02-01
NO850397L (no) 1985-08-05
EP0152255A3 (en) 1987-06-16
EP0152255A2 (en) 1985-08-21
PT79917B (en) 1987-02-05
NO167744B (no) 1991-08-26
US4698329A (en) 1987-10-06
DK47285A (da) 1985-08-04
HUT38105A (en) 1986-04-28
DK47285D0 (da) 1985-02-01
FI850429L (fi) 1985-08-04
KR910007576B1 (ko) 1991-09-28
HU198951B (en) 1989-12-28
JPS60163899A (ja) 1985-08-26

Similar Documents

Publication Publication Date Title
NO167744C (no) Analogifremgangsmaate til fremstilling av renininhiberendepeptider.
NO161558C (no) Analogifremgangsmaate til fremstilling av antihypertensivebenzazepin-2-oner.
NO852907L (no) Fremgangsmaate til fremstilling av polyvinylklorid.
NO152551C (no) Fremgangsmaate til fremstilling av rent silisium.
NO160263C (no) Analogifremgangsmaate til fremstilling av antibiotisk acetylerytromycistearat.
NO861573L (no) Fremgangsmaate til fremstilling av klorhydrat av fenyl-1-dietylaminokarbonyl-1-aminometyl-2-cyklopropan (z).
NO873183D0 (no) Fremgangsmaate til fremstilling av reninhemmende di- og tri-peptider.
NO832022L (no) Fremgangsmaate til fremstilling av amidiner
IT8421622A0 (it) Procedimento per la preparazione di peptidi.
NO861486L (no) Fremgangsmaate til fremstilling av fluorerte benzyltriazolforbindelser.
NO855067L (no) Fremgangsmaate for fremstilling av n-formyl-alfa-aspartyl-fenylalanin.
NO853066L (no) Fremgansmaate til fremstilling av 3-karbonyl-1-aminoalkyl-1h-indoler.
NO851310L (no) Stereospesifikk fremgangsmaate til fremstilling av acetonoksyazetidinon.
NO161177C (no) Analogifremgangsm te til fremstilling av terapeutisk aktive tioetere.
NO874575L (no) Fremgangsmaate til fremstilling av fiberarmerte komposittmaterialer inneholdende polyarylensulfidsulfon.
NO163061C (no) Fremgangsmaate til fremstilling av ferromangan.
NO863389L (no) Fremgangsmaate til fremstilling av substituerte toluidiner.
NO864342D0 (no) Fremgangsmaate til inhibering av den hydrogeninduserte korrosjon av metalliske materialer.
NO161064C (no) Analogifremgangsmaate til fremstilling av fenyl-nonatetraensyrederivater.
NO165637C (no) Fremgangsmaate for fremstilling av etoksylert lignitt.
NO873339D0 (no) Fremgangsmaate til fremstilling av hydrogenperoksyd.
NO863604D0 (no) Fremgangsmaate til fremstilling av ferroborlegeringer.
NO880106L (no) Fremgangsmaate til fremstilling av kalknitrogen.
NO862858L (no) Fremgangsmaate til fremstilling av traadholdige komposittmaterialer.
NO166709C (no) Fremgangsmaate for fremstilling av akrylamider.