DK420588A - (aryl eller heteroaromatisk methyl)-2,2'-bi-1h-imidazoler, deres fremstilling og anvendelse - Google Patents

(aryl eller heteroaromatisk methyl)-2,2'-bi-1h-imidazoler, deres fremstilling og anvendelse

Info

Publication number
DK420588A
DK420588A DK420588A DK420588A DK420588A DK 420588 A DK420588 A DK 420588A DK 420588 A DK420588 A DK 420588A DK 420588 A DK420588 A DK 420588A DK 420588 A DK420588 A DK 420588A
Authority
DK
Denmark
Prior art keywords
aryl
imidazoles
preparation
heteroaromatic methyl
substituted
Prior art date
Application number
DK420588A
Other languages
English (en)
Other versions
DK420588D0 (da
Inventor
Donald P Matthews
James R Mccarthy
Jeffrey P Whitten
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of DK420588D0 publication Critical patent/DK420588D0/da
Publication of DK420588A publication Critical patent/DK420588A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK420588A 1987-07-28 1988-07-27 (aryl eller heteroaromatisk methyl)-2,2'-bi-1h-imidazoler, deres fremstilling og anvendelse DK420588A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/078,352 US4839375A (en) 1987-07-28 1987-07-28 (Aryl or heteroaromatic methyl)-2,2'-bi-1H-imidazoles and their use as anti-hypertensive agents

Publications (2)

Publication Number Publication Date
DK420588D0 DK420588D0 (da) 1988-07-27
DK420588A true DK420588A (da) 1989-01-29

Family

ID=22143494

Family Applications (1)

Application Number Title Priority Date Filing Date
DK420588A DK420588A (da) 1987-07-28 1988-07-27 (aryl eller heteroaromatisk methyl)-2,2'-bi-1h-imidazoler, deres fremstilling og anvendelse

Country Status (19)

Country Link
US (1) US4839375A (da)
EP (1) EP0301456B1 (da)
JP (1) JP2750578B2 (da)
KR (1) KR970011301B1 (da)
CN (1) CN1016173B (da)
AT (1) ATE101151T1 (da)
AU (1) AU605609B2 (da)
CA (1) CA1338786C (da)
DE (1) DE3887585T2 (da)
DK (1) DK420588A (da)
ES (1) ES2063008T3 (da)
FI (1) FI883499A (da)
HU (1) HU202861B (da)
IL (1) IL87217A (da)
NO (1) NO169841C (da)
NZ (1) NZ225561A (da)
PH (1) PH26551A (da)
PT (1) PT88121B (da)
ZA (1) ZA885360B (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO328281B1 (no) * 1998-03-20 2010-01-25 Res Inst Petroleum Processing Fremgangsmate for omdannelse av hydrokarbonoljer

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4670563A (en) * 1984-06-20 1987-06-02 Sanofi Imidazolides as intermediates for the synthesis of cytotoxic conjugates
ZA868809B (en) * 1985-11-25 1987-07-29 Merrell Dow Pharma Novel 2,2'-bi-1h-imidazoles
JP2581556B2 (ja) * 1986-05-06 1997-02-12 メレルダウファーマスーティカルズ インコーポレーテッド 新規なドパミンベ−タヒドロキシラ−ゼ抑制剤

Also Published As

Publication number Publication date
AU605609B2 (en) 1991-01-17
EP0301456A3 (en) 1990-12-05
PT88121A (pt) 1989-07-31
EP0301456B1 (en) 1994-02-02
DK420588D0 (da) 1988-07-27
CN1016173B (zh) 1992-04-08
FI883499A (fi) 1989-01-29
ZA885360B (en) 1989-03-29
DE3887585D1 (de) 1994-03-17
IL87217A0 (en) 1988-12-30
FI883499A0 (fi) 1988-07-25
KR970011301B1 (ko) 1997-07-09
DE3887585T2 (de) 1994-05-26
EP0301456A2 (en) 1989-02-01
CN1034718A (zh) 1989-08-16
NO883322L (no) 1989-01-30
US4839375A (en) 1989-06-13
PT88121B (pt) 1995-03-01
JPS6440465A (en) 1989-02-10
NO169841C (no) 1992-08-12
HUT53900A (en) 1990-12-28
CA1338786C (en) 1996-12-10
PH26551A (en) 1992-08-19
IL87217A (en) 1992-07-15
JP2750578B2 (ja) 1998-05-13
AU1976588A (en) 1989-02-02
HU202861B (en) 1991-04-29
ES2063008T3 (es) 1995-01-01
KR890002112A (ko) 1989-04-08
NZ225561A (en) 1990-12-21
ATE101151T1 (de) 1994-02-15
NO169841B (no) 1992-05-04
NO883322D0 (no) 1988-07-27

Similar Documents

Publication Publication Date Title
DK89595A (da) Fremgangsmåde til fremstilling af 1-(3-dimethylaminopropyl)-1'-(4-fluorphenyl)-1,3-dihydroisobenzofuran-5-carbonnitril
ES2040261T3 (es) Procedimiento para preparar acidos 6-fluor-4-oxo-1,4-dihidroquinolina-3-carboxilicos sustituidos y acidos 9-fluor-3-metil-7-oxo-2,3-dihidro-7h-pirido(1,2,3-de)(1,4)benzoxazina-6-carboxilico sustituidos.
NO902301D0 (no) Fremgangsmaate for fremstilling av diarylstyrylkinolin-disyrer.
MX17846A (es) Proceso para la preparacion de nuevos derivados de 9h purina.
ES8503346A1 (es) "un procedimiento para preparar un derivado de -(4-(2-piridil)-pi-peracino)-alcanoilanilida".
DE69122866T2 (de) Herstellung von substituierten piperidinen
ES2058285T3 (es) Procedimiento para la preparacion de derivados de indolinona sustituida.
ES545195A0 (es) Un procedimiento para preparar derivados de purina
IT8420358A0 (it) Procedimento di preparazione di derivati 1-carbamoilmetilici di 4-idrossi-2-osso-pirrolidina nonche' di intermedi per ottenere tali composti.
FR2567514B1 (fr) Nouveaux ether-oxydes derives de cyclopropylphenols
DK420588A (da) (aryl eller heteroaromatisk methyl)-2,2'-bi-1h-imidazoler, deres fremstilling og anvendelse
ES2044900T3 (es) Un proceso para la preparacion de un derivado de antraciclina.
NO904135D0 (no) Fremgangsmaate for fremstilling av nye alkylpiperidiner.
DK23887D0 (da) Benzimidazolderivater
ES2033256T3 (es) Procedimiento para preparar derivados fluorados de la vitamina d3.
ES552874A0 (es) Un procedimiento para preparar benzo (c)-1,5-naftiridinas
DK0521766T3 (da) Hidtil ukendt fremgangsmåde til syntese af enantiomerer af 3-aminochromanderivater
ES535794A0 (es) Un procedimiento para preparar nuevas 5-aminometil-imidazol-1-il-1,3-dialquil-1h-pirazol-4-il-aroil-metanonas
DK437787A (da) 2,6-bis-(chlormethyloxy-carbonyloxymethyl)-pyridinsamt fremgangsmaade til fremstilling deraf
KR830005134A (ko) 항부정맥 작용 및 혈소판 응집 억제 작용을 갖는 심근 보호용 피롤 유도체의 제조방법
IT7827750A0 (it) Processo per la preparazione di derivati 1,4-diidro-piridinici.

Legal Events

Date Code Title Description
ATS Application withdrawn