DK39888A - Stabilt thrombinpraeparat, dets fremstilling og anvendelse - Google Patents

Stabilt thrombinpraeparat, dets fremstilling og anvendelse

Info

Publication number
DK39888A
DK39888A DK039888A DK39888A DK39888A DK 39888 A DK39888 A DK 39888A DK 039888 A DK039888 A DK 039888A DK 39888 A DK39888 A DK 39888A DK 39888 A DK39888 A DK 39888A
Authority
DK
Denmark
Prior art keywords
thrombine
stable
preparation
manufacturing
thrombine preparation
Prior art date
Application number
DK039888A
Other languages
English (en)
Other versions
DK167210B1 (da
DK39888D0 (da
Inventor
Steven Bernard Silbering
Jr Rowland Parker Blythe
Russell Ulmer Nesbitt
Mahdi Bakir Fawzi
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21726876&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK39888(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of DK39888D0 publication Critical patent/DK39888D0/da
Publication of DK39888A publication Critical patent/DK39888A/da
Application granted granted Critical
Publication of DK167210B1 publication Critical patent/DK167210B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6429—Thrombin (3.4.21.5)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21005—Thrombin (3.4.21.5)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
DK039888A 1987-01-28 1988-01-27 Stabilt thrombinpraeparat, fremgangsmaade til dets fremstilling og hemostat indeholdende praeparatet DK167210B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US755587A 1987-01-28 1987-01-28
US755587 2001-01-05

Publications (3)

Publication Number Publication Date
DK39888D0 DK39888D0 (da) 1988-01-27
DK39888A true DK39888A (da) 1988-07-29
DK167210B1 DK167210B1 (da) 1993-09-20

Family

ID=21726876

Family Applications (1)

Application Number Title Priority Date Filing Date
DK039888A DK167210B1 (da) 1987-01-28 1988-01-27 Stabilt thrombinpraeparat, fremgangsmaade til dets fremstilling og hemostat indeholdende praeparatet

Country Status (9)

Country Link
EP (1) EP0277096B1 (da)
JP (1) JP2837847B2 (da)
AU (1) AU602047B2 (da)
DE (1) DE3872534D1 (da)
DK (1) DK167210B1 (da)
IE (1) IE880183L (da)
NZ (1) NZ223311A (da)
PH (1) PH25144A (da)
ZA (1) ZA88227B (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL93618A0 (en) * 1989-03-06 1990-12-23 Lilly Co Eli Improved diluent formulation for daptomycin
DK223389D0 (da) * 1989-05-05 1989-05-05 Ferrosan As Saarsvamp
IE73210B1 (en) * 1990-01-24 1997-05-07 Warner Lambert Co Process for the production of thrombin and high purity thrombin preparation thereby obtained
US5925738A (en) * 1995-12-01 1999-07-20 The American National Red Cross Methods of production and use of liquid formulations of plasma proteins
DE69724243T2 (de) * 1996-04-04 2004-06-17 Baxter Ag Blutstillender schwamm auf kollagenbasis
AU2002342672A1 (en) * 2001-09-11 2003-03-24 Nascacell Gmbh Method for screening for inhibitors of protein/protein interaction and corresponding ribozymes
WO2005074977A1 (ja) * 2004-02-04 2005-08-18 Mitsubishi Pharma Corporation パラオキソナーゼ含有製剤
AU2009220808B2 (en) 2008-03-03 2014-01-16 Omrix Biopharmaceuticals Ltd. A gelatin sponge comprising an active ingredient, its preparation and use
KR20100134078A (ko) 2008-04-16 2010-12-22 잇빤 자이단호진 가가쿠오요비겟세이료호겐쿠쇼 트롬빈 고정화 생체 흡수성 시트 제제의 제조방법
US9149529B2 (en) 2012-10-24 2015-10-06 Orthovita, Inc. Stable compositions containing thrombin and methods for preparation and use thereof
IL229134A0 (en) 2013-10-29 2014-03-31 Omrix Biopharmaceuticals Ltd Compounds and methods for stabilizing thrombin activity
IL234246A0 (en) 2014-08-21 2014-11-30 Omrix Biopharmaceuticals Ltd Stabilized thrombin
CN106568765B (zh) * 2015-10-12 2020-08-04 上海长岛生物技术有限公司 用于抗凝血酶iii活性测定的凝血酶发色底物液、凝血酶水溶液、方法以及试剂盒
IL261190A (en) * 2018-08-16 2019-01-31 Omrix Biopharmaceuticals Ltd Stable liquid preparations of thrombin

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2433299A (en) * 1944-01-22 1947-12-23 Parke Davis & Co Blood coagulant and method of preserving same
FR912350A (fr) * 1944-09-27 1946-08-06 Hoffmann La Roche Procédé pour la préparation de solutions stables de thrombine
JPS5639782A (en) * 1979-09-04 1981-04-15 Dai Ichi Pure Chem Co Ltd Stabilization of thrombin
JPS5739849A (en) * 1980-06-30 1982-03-05 Apuraido Medical Debaishizu In Prepared bandage having coagulant composition and method
US4363319A (en) * 1980-06-30 1982-12-14 Applied Medical Devices, Inc. Ready-to-use bandage incorporating a coagulant composition and method of preparing same
JPS61253900A (ja) * 1985-05-07 1986-11-11 株式会社日立製作所 櫛状接続ピンのセパレ−トチヤツク装置
US4696812A (en) * 1985-10-28 1987-09-29 Warner-Lambert Company Thrombin preparations
JPH0764747A (ja) * 1993-08-31 1995-03-10 Toshiba Corp 機器動作の動画表示方法およびその方法を用いた機器動作の動画表示装置

Also Published As

Publication number Publication date
DE3872534D1 (de) 1992-08-13
DE3872534T2 (da) 1993-01-28
EP0277096A2 (en) 1988-08-03
JP2837847B2 (ja) 1998-12-16
EP0277096A3 (en) 1989-04-19
JPS63192723A (ja) 1988-08-10
NZ223311A (en) 1990-10-26
DK167210B1 (da) 1993-09-20
AU1039488A (en) 1988-08-04
ZA88227B (en) 1988-06-30
DK39888D0 (da) 1988-01-27
EP0277096B1 (en) 1992-07-08
IE880183L (en) 1988-07-28
PH25144A (en) 1991-02-19
AU602047B2 (en) 1990-09-27

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed