DK3947708T3 - Fremgangsmåde og system til forbedret kalibrering af kreatinin/kreatin-sensorer - Google Patents

Fremgangsmåde og system til forbedret kalibrering af kreatinin/kreatin-sensorer Download PDF

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Publication number
DK3947708T3
DK3947708T3 DK19734962.4T DK19734962T DK3947708T3 DK 3947708 T3 DK3947708 T3 DK 3947708T3 DK 19734962 T DK19734962 T DK 19734962T DK 3947708 T3 DK3947708 T3 DK 3947708T3
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Prior art keywords
creatinine
improved calibration
creatine sensors
creatine
sensors
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DK19734962.4T
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Danish (da)
English (en)
Inventor
Xiaoxian Xu
Prasad Pamidi
David Raimondi
Miklos Erdosy
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Instr Laboratory Co
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    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
    • B01D71/06—Organic material
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    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3275—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
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    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
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DK19734962.4T 2019-04-05 2019-06-03 Fremgangsmåde og system til forbedret kalibrering af kreatinin/kreatin-sensorer DK3947708T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962830191P 2019-04-05 2019-04-05
PCT/US2019/035152 WO2020204972A1 (en) 2019-04-05 2019-06-03 Improved calibration accuracy method for creatinine/creatine sensors

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DK3947708T3 true DK3947708T3 (da) 2024-03-11

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DK19734962.4T DK3947708T3 (da) 2019-04-05 2019-06-03 Fremgangsmåde og system til forbedret kalibrering af kreatinin/kreatin-sensorer
DK19739734.2T DK3947711T3 (da) 2019-04-05 2019-06-03 Urinstofbiosensorer, der er stabiliseret ved rumtemperatur

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DK19739734.2T DK3947711T3 (da) 2019-04-05 2019-06-03 Urinstofbiosensorer, der er stabiliseret ved rumtemperatur

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US (6) US11327042B2 (https=)
EP (5) EP3947710A1 (https=)
JP (6) JP7135121B2 (https=)
KR (5) KR102480669B1 (https=)
CN (6) CN112513285B (https=)
AU (3) AU2019440163B2 (https=)
CA (3) CA3105013C (https=)
DK (2) DK3947708T3 (https=)
ES (1) ES3038379T3 (https=)
WO (5) WO2020204975A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11327042B2 (en) 2019-04-05 2022-05-10 Instrumentation Laboratory Company Compositions and methods for improved creatinine measurement accuracy and uses thereof
US12139741B2 (en) 2019-10-25 2024-11-12 Instrumentation Laboratory Company Biocide compositions compatible with enzyme biosensors and methods of use thereof
US12298268B2 (en) * 2020-05-21 2025-05-13 Nova Biomedical Corporation Single-use disposable reference sensor
US20230041320A1 (en) * 2021-08-03 2023-02-09 Polymer Technology Systems, Inc. Systems and Methods for Quantifying The Specific Activity of Creatininase
ES3054584T3 (en) 2022-02-09 2026-02-04 Instr Laboratory Co Sensor for measuring ionized magnesium
CN114705674B (zh) * 2022-05-10 2025-07-22 光景生物科技(苏州)有限公司 一种全血中肌酸和肌酐的定量检测方法
WO2025029820A1 (en) * 2023-07-31 2025-02-06 Abbott Diabetes Care Inc. Background interference mitigation for high sensitivity creatinine sensing
KR102800865B1 (ko) 2024-07-31 2025-05-07 전남대학교 산학협력단 신규한 크레아티닌 정량 장치

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5861459A (ja) * 1981-10-07 1983-04-12 Hitachi Ltd クレアチンとクレアチニンの分析装置
JPS6475000A (en) * 1987-09-14 1989-03-20 Shimadzu Corp Method and equipment for analyzing creatinine
US5464747A (en) * 1993-10-29 1995-11-07 Boehringer Mannheim Corporation Oxidation-resistant muteins of β-galactosidase fragments
EP0944731B1 (en) * 1996-11-14 2006-01-18 Radiometer Medical ApS Enzyme sensor
DE69810194T2 (de) 1997-06-03 2003-11-20 Matsushita Electric Industrial Co. Ltd., Osaka Cholesterinsensor
JP3635263B2 (ja) 2000-03-01 2005-04-06 ラジオメーター・メディカル・アクティーゼルスカブ 固体状態参照系を持つ電極デバイス
AT408662B (de) * 2000-05-16 2002-02-25 Hoffmann La Roche Creatinin-sensor
AT409040B (de) 2000-08-11 2002-05-27 Roche Diagnostics Gmbh Creatininsensor-kalibration
US6872297B2 (en) 2001-05-31 2005-03-29 Instrumentation Laboratory Company Analytical instruments, biosensors and methods thereof
US6960466B2 (en) 2001-05-31 2005-11-01 Instrumentation Laboratory Company Composite membrane containing a cross-linked enzyme matrix for a biosensor
US6767441B1 (en) 2001-07-31 2004-07-27 Nova Biomedical Corporation Biosensor with peroxidase enzyme
ES2633729T3 (es) * 2001-08-22 2017-09-25 Instrumentation Laboratory Company Método para calibrar sensores electroquímicos
JP4567333B2 (ja) 2001-08-24 2010-10-20 センサーテック・リミテッド 高感度電位差測定センサを製造する方法
US7285198B2 (en) 2004-02-23 2007-10-23 Mysticmd, Inc. Strip electrode with conductive nano tube printing
GB0227424D0 (en) 2002-11-25 2002-12-31 Univ Warwick Coatings
US20040256227A1 (en) 2003-02-11 2004-12-23 Jungwon Shin Electrochemical urea sensors and methods of making the same
JP4088312B2 (ja) 2003-10-30 2008-05-21 アークレイ株式会社 バイオセンサおよびその製造方法
DK1692522T3 (da) 2003-11-28 2012-04-02 Radiometer Medical Aps Referencevæske
US7699964B2 (en) * 2004-02-09 2010-04-20 Abbott Diabetes Care Inc. Membrane suitable for use in an analyte sensor, analyte sensor, and associated method
US8989833B2 (en) * 2004-07-13 2015-03-24 Dexcom, Inc. Transcutaneous analyte sensor
US7959791B2 (en) 2005-05-17 2011-06-14 Radiometer Medical Aps Enzyme sensor with a cover membrane layer covered by a hydrophilic polymer
WO2006122553A1 (en) * 2005-05-17 2006-11-23 Radiometer Medical Aps Enzyme sensor including a water-containing spacer layer
WO2006122552A1 (en) * 2005-05-17 2006-11-23 Radiometer Medical Aps Method of stabilising or reactivating a creatinine sensor with a solution of a divalent manganese ion
DK1889075T3 (da) 2005-05-17 2013-09-02 Radiometer Medical Aps Fremgangsmåde til stabilisering eller reaktivering af en kreatininsensor med en opløsning af en divalent manganion
KR100726963B1 (ko) * 2005-06-15 2007-06-14 김경훈 바이오센서용 우레아제 고정화막의 제조 방법
US7799195B2 (en) * 2005-09-02 2010-09-21 Vladislav Dolnik Neutral polysaccharide wall coating for electrophoretic separations in capillaries and microchannels
US8617366B2 (en) * 2005-12-12 2013-12-31 Nova Biomedical Corporation Disposable urea sensor and system for determining creatinine and urea nitrogen-to-creatinine ratio in a single device
US9556471B2 (en) * 2006-08-09 2017-01-31 Flir Detection, Inc. Enzyme containing liquid and delivery system for detection of analytes on surfaces
US7687103B2 (en) * 2006-08-31 2010-03-30 Gamida For Life B.V. Compositions and methods for preserving permeation layers for use on active electronic matrix devices
IES20070774A2 (en) 2007-10-24 2008-12-24 Nat Univ Ireland Maynooth Monitoring target endogenous species in the brain
US8268604B2 (en) 2007-12-20 2012-09-18 Abbott Point Of Care Inc. Compositions for forming immobilized biological layers for sensing
US20120181189A1 (en) 2009-09-24 2012-07-19 Fresenius Medical Care Holdings, Inc. Amperometric Creatinine Biosensor With Immobilized Enzyme-Polymer Composition And Systems Using Same, And Methods
US9233788B2 (en) * 2010-01-22 2016-01-12 Bayer Healthcare Llc Biosensor desiccant system having enhanced measurement performance
JP2014153243A (ja) 2013-02-12 2014-08-25 Tanita Corp バイオセンサおよびこれを用いた測定方法
WO2014159193A1 (en) * 2013-03-14 2014-10-02 Instrumentation Laboratory Company Whole blood hemolysis sensor
WO2014150876A2 (en) 2013-03-15 2014-09-25 Abbott Point Of Care Inc Biosensor structures for improved point of care testing and methods of manufacture thereof
EP4530635A3 (en) 2014-12-18 2025-06-25 Radiometer Medical ApS Method for calibrating a device for measuring the concentration of creatinine
DK3234562T3 (da) 2014-12-18 2020-02-03 Radiometer Medical Aps Kalibreringskoncept til amperometrisk creatininsensor med korrigering for endogene modulatorer
DK3234563T3 (da) 2014-12-18 2025-02-10 Radiometer Medical Aps Fremgangsmåde til kalibrering af en indretning til måling af koncentrationen af kreatinin
EP3380833B1 (en) * 2015-11-27 2019-12-25 Radiometer Medical ApS An outer layer for enzyme sensors
JP7011906B2 (ja) * 2017-08-25 2022-01-27 国立大学法人 筑波大学 クレアチニンセンサ
KR102573459B1 (ko) * 2017-08-28 2023-09-04 디에스엠 아이피 어셋츠 비.브이. 폴리우레탄 블렌드를 포함하는 합성 멤브레인 조성물
US11327042B2 (en) 2019-04-05 2022-05-10 Instrumentation Laboratory Company Compositions and methods for improved creatinine measurement accuracy and uses thereof

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