DK3777833T3 - Dopa-decarboxylase-inhibitorsammensætninger - Google Patents
Dopa-decarboxylase-inhibitorsammensætninger Download PDFInfo
- Publication number
- DK3777833T3 DK3777833T3 DK20198371.5T DK20198371T DK3777833T3 DK 3777833 T3 DK3777833 T3 DK 3777833T3 DK 20198371 T DK20198371 T DK 20198371T DK 3777833 T3 DK3777833 T3 DK 3777833T3
- Authority
- DK
- Denmark
- Prior art keywords
- decarboxylase inhibitor
- inhibitor compositions
- dopa decarboxylase
- dopa
- compositions
- Prior art date
Links
- 229940081615 DOPA decarboxylase inhibitor Drugs 0.000 title 1
- 239000000534 dopa decarboxylase inhibitor Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/133—Amines having hydroxy groups, e.g. sphingosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dermatology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Psychology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461952477P | 2014-03-13 | 2014-03-13 | |
| US201461990967P | 2014-05-09 | 2014-05-09 | |
| EP15731727.2A EP3116475B1 (en) | 2014-03-13 | 2015-03-12 | Dopa decarboxylase inhibitor compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3777833T3 true DK3777833T3 (da) | 2023-12-18 |
Family
ID=53488380
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK15731727.2T DK3116475T3 (da) | 2014-03-13 | 2015-03-12 | Dopa-decarboxylasehæmmersammensætninger |
| DK20198371.5T DK3777833T3 (da) | 2014-03-13 | 2015-03-12 | Dopa-decarboxylase-inhibitorsammensætninger |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK15731727.2T DK3116475T3 (da) | 2014-03-13 | 2015-03-12 | Dopa-decarboxylasehæmmersammensætninger |
Country Status (19)
| Country | Link |
|---|---|
| US (4) | US10022320B2 (OSRAM) |
| EP (3) | EP4299128A3 (OSRAM) |
| JP (2) | JP6591995B2 (OSRAM) |
| CN (1) | CN106413754B (OSRAM) |
| AU (1) | AU2015228369B2 (OSRAM) |
| BR (1) | BR112016021034A8 (OSRAM) |
| CA (1) | CA2942244C (OSRAM) |
| DK (2) | DK3116475T3 (OSRAM) |
| ES (2) | ES2967693T3 (OSRAM) |
| FI (1) | FI3777833T3 (OSRAM) |
| HR (2) | HRP20231716T1 (OSRAM) |
| HU (2) | HUE064818T2 (OSRAM) |
| IL (1) | IL247668B (OSRAM) |
| MX (1) | MX2016011837A (OSRAM) |
| PL (2) | PL3116475T3 (OSRAM) |
| PT (2) | PT3116475T (OSRAM) |
| RS (1) | RS65060B1 (OSRAM) |
| RU (1) | RU2684105C2 (OSRAM) |
| WO (1) | WO2015136538A1 (OSRAM) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8193243B2 (en) | 2009-05-19 | 2012-06-05 | Neuroderm, Ltd. | Continuous administration of dopa decarboxylase inhibitors and compositions for same |
| JP5902705B2 (ja) | 2010-11-15 | 2016-04-13 | ニューロダーム リミテッドNeuroderm Ltd | L−ドーパ、ドーパデカルボキシラーゼ阻害剤、カテコール−o−メチルトランスフェラーゼ阻害剤、およびそれらのための組成物の継続的投与 |
| US10258585B2 (en) | 2014-03-13 | 2019-04-16 | Neuroderm, Ltd. | DOPA decarboxylase inhibitor compositions |
| EP4299128A3 (en) | 2014-03-13 | 2024-04-17 | Neuroderm Ltd. | Dopa decarboxylase inhibitor compositions |
| CA2997791A1 (en) | 2015-09-30 | 2017-04-06 | Duke University | Ascorbate formulations and methods of use as contrast agents |
| WO2018154447A1 (en) * | 2017-02-21 | 2018-08-30 | Neuroderm Ltd | Dopa decarboxylase inhibitor compositions |
| SG11202104499RA (en) | 2018-11-15 | 2021-05-28 | Abbvie Inc | Pharmaceutical formulations for subcutaneous administration |
| WO2020178810A1 (en) * | 2019-03-04 | 2020-09-10 | Neuroderm, Ltd. | Pharmaceutical compositions comprising levodopa amide derivatives and uses thereof |
| CN111701024B (zh) * | 2020-05-26 | 2022-05-24 | 上海京新生物医药有限公司 | 一种左旋多巴制剂及其制备方法及其应用 |
| US11213502B1 (en) | 2020-11-17 | 2022-01-04 | Neuroderm, Ltd. | Method for treatment of parkinson's disease |
| US11331293B1 (en) | 2020-11-17 | 2022-05-17 | Neuroderm, Ltd. | Method for treatment of Parkinson's disease |
| US11844754B2 (en) | 2020-11-17 | 2023-12-19 | Neuroderm, Ltd. | Methods for treatment of Parkinson's disease |
| CN113396897B (zh) * | 2021-07-26 | 2022-06-07 | 苏州华测生物技术有限公司 | 一种稳定生物基质中卡比多巴/左旋多巴的方法 |
| US12161612B2 (en) | 2023-04-14 | 2024-12-10 | Neuroderm, Ltd. | Methods and compositions for reducing symptoms of Parkinson's disease |
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| EP4299128A3 (en) | 2014-03-13 | 2024-04-17 | Neuroderm Ltd. | Dopa decarboxylase inhibitor compositions |
| US10258585B2 (en) | 2014-03-13 | 2019-04-16 | Neuroderm, Ltd. | DOPA decarboxylase inhibitor compositions |
| MX381069B (es) | 2014-10-21 | 2025-03-12 | Abbvie Inc | Profármacos de carbidopa y l-dopa y métodos de uso. |
| EP3380076A2 (en) | 2015-11-24 | 2018-10-03 | Neuroderm, Ltd. | Pharmaceutical compositions comprising levodopa amide and uses thereof |
| WO2018154447A1 (en) | 2017-02-21 | 2018-08-30 | Neuroderm Ltd | Dopa decarboxylase inhibitor compositions |
| WO2019038639A1 (en) | 2017-08-21 | 2019-02-28 | Neuroderm Ltd | FREE LEOPODOPA CRYSTALLINE AMIDE BASE AND METHODS OF MAKING AND USING SAME |
| AR112472A1 (es) | 2017-08-21 | 2019-10-30 | Neuroderm Ltd | Forma de sales cristalinas de amida de levodopa y métodos para elaborarlas y usarlas |
| AR112473A1 (es) | 2017-08-21 | 2019-10-30 | Neuroderm Ltd | Proceso para preparar amida de levodopa purificada |
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2015
- 2015-03-12 EP EP23204007.1A patent/EP4299128A3/en not_active Withdrawn
- 2015-03-12 PT PT157317272T patent/PT3116475T/pt unknown
- 2015-03-12 DK DK15731727.2T patent/DK3116475T3/da active
- 2015-03-12 FI FIEP20198371.5T patent/FI3777833T3/fi active
- 2015-03-12 JP JP2016556969A patent/JP6591995B2/ja active Active
- 2015-03-12 US US14/645,848 patent/US10022320B2/en active Active
- 2015-03-12 CN CN201580024073.7A patent/CN106413754B/zh active Active
- 2015-03-12 ES ES20198371T patent/ES2967693T3/es active Active
- 2015-03-12 RU RU2016135952A patent/RU2684105C2/ru active
- 2015-03-12 CA CA2942244A patent/CA2942244C/en active Active
- 2015-03-12 HR HRP20231716TT patent/HRP20231716T1/hr unknown
- 2015-03-12 MX MX2016011837A patent/MX2016011837A/es active IP Right Grant
- 2015-03-12 EP EP15731727.2A patent/EP3116475B1/en active Active
- 2015-03-12 HR HRP20201948TT patent/HRP20201948T1/hr unknown
- 2015-03-12 PT PT201983715T patent/PT3777833T/pt unknown
- 2015-03-12 HU HUE20198371A patent/HUE064818T2/hu unknown
- 2015-03-12 DK DK20198371.5T patent/DK3777833T3/da active
- 2015-03-12 HU HUE15731727A patent/HUE052642T2/hu unknown
- 2015-03-12 PL PL15731727T patent/PL3116475T3/pl unknown
- 2015-03-12 AU AU2015228369A patent/AU2015228369B2/en active Active
- 2015-03-12 ES ES15731727T patent/ES2836325T3/es active Active
- 2015-03-12 RS RS20240006A patent/RS65060B1/sr unknown
- 2015-03-12 BR BR112016021034A patent/BR112016021034A8/pt not_active Application Discontinuation
- 2015-03-12 EP EP20198371.5A patent/EP3777833B1/en active Active
- 2015-03-12 PL PL20198371.5T patent/PL3777833T3/pl unknown
- 2015-03-12 WO PCT/IL2015/050258 patent/WO2015136538A1/en not_active Ceased
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2016
- 2016-09-06 IL IL247668A patent/IL247668B/en active IP Right Grant
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2018
- 2018-06-14 US US16/008,228 patent/US10624839B2/en active Active
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2019
- 2019-09-19 JP JP2019170864A patent/JP6770158B2/ja active Active
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2020
- 2020-03-16 US US16/819,740 patent/US20210038505A1/en not_active Abandoned
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2022
- 2022-09-01 US US17/901,078 patent/US20230240980A1/en not_active Abandoned
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