DK3569690T3 - Human-afledte bakterier som inducerer proliferation eller akkumulation af regulatoriske t-celler - Google Patents

Human-afledte bakterier som inducerer proliferation eller akkumulation af regulatoriske t-celler Download PDF

Info

Publication number
DK3569690T3
DK3569690T3 DK19178787.8T DK19178787T DK3569690T3 DK 3569690 T3 DK3569690 T3 DK 3569690T3 DK 19178787 T DK19178787 T DK 19178787T DK 3569690 T3 DK3569690 T3 DK 3569690T3
Authority
DK
Denmark
Prior art keywords
regulatory
accumulation
cells
human
induce proliferation
Prior art date
Application number
DK19178787.8T
Other languages
Danish (da)
English (en)
Inventor
Kenya Honda
Koji Atarashi
Takeshi Tanoue
Masahira Hattori
Hidetoshi Morita
Original Assignee
Univ Tokyo
School Corporation Azabu Veterinary Medicine Educational Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48535050&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK3569690(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Tokyo, School Corporation Azabu Veterinary Medicine Educational Inst filed Critical Univ Tokyo
Application granted granted Critical
Publication of DK3569690T3 publication Critical patent/DK3569690T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/742—Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/745—Bifidobacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K2035/11—Medicinal preparations comprising living procariotic cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/145—Clostridium
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Mycology (AREA)
  • Wood Science & Technology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Toxicology (AREA)
  • Transplantation (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
DK19178787.8T 2011-12-01 2012-11-29 Human-afledte bakterier som inducerer proliferation eller akkumulation af regulatoriske t-celler DK3569690T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161565976P 2011-12-01 2011-12-01
US201261607360P 2012-03-06 2012-03-06
EP12854485.5A EP2785828B1 (en) 2011-12-01 2012-11-29 Human-derived bacteria that induce proliferation or accumulation of regulatory t cells

Publications (1)

Publication Number Publication Date
DK3569690T3 true DK3569690T3 (da) 2024-11-11

Family

ID=48535050

Family Applications (2)

Application Number Title Priority Date Filing Date
DK21198256.6T DK3978598T3 (da) 2011-12-01 2012-11-29 Human-afledte bakterier som inducerer proliferation eller akkumulation af regulatoriske t-celler
DK19178787.8T DK3569690T3 (da) 2011-12-01 2012-11-29 Human-afledte bakterier som inducerer proliferation eller akkumulation af regulatoriske t-celler

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK21198256.6T DK3978598T3 (da) 2011-12-01 2012-11-29 Human-afledte bakterier som inducerer proliferation eller akkumulation af regulatoriske t-celler

Country Status (10)

Country Link
US (11) US10238694B2 (enExample)
EP (4) EP4477750A3 (enExample)
JP (6) JP6306507B2 (enExample)
CN (3) CN116942833A (enExample)
CA (1) CA2892588A1 (enExample)
DK (2) DK3978598T3 (enExample)
ES (2) ES2994320T3 (enExample)
FI (2) FI3978598T3 (enExample)
HK (1) HK1204008A1 (enExample)
WO (1) WO2013080561A1 (enExample)

Families Citing this family (131)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPQ899700A0 (en) 2000-07-25 2000-08-17 Borody, Thomas Julius Probiotic recolonisation therapy
WO2011151941A1 (ja) 2010-06-04 2011-12-08 国立大学法人東京大学 制御性ｔ細胞の増殖または集積を誘導する作用を有する組成物
CA2807242C (en) 2010-08-04 2017-05-02 Thomas Julius Borody Compositions for fecal floral transplantation and methods for making and using them and devices for delivering them
WO2012048152A2 (en) 2010-10-07 2012-04-12 Mazmanian Sarkis K Probiotic therapies for autism
AU2012225305B2 (en) 2011-03-09 2017-06-08 Regents Of The University Of Minnesota Compositions and methods for transplantation of colon microbiota
GB201112091D0 (en) 2011-07-14 2011-08-31 Gt Biolog Ltd Bacterial strains isolated from pigs
GB201117313D0 (en) 2011-10-07 2011-11-16 Gt Biolog Ltd Bacterium for use in medicine
JP6306507B2 (ja) * 2011-12-01 2018-04-18 国立大学法人 東京大学 制御性ｔ細胞の増殖または集積を誘導するヒト由来細菌
WO2013130773A2 (en) 2012-02-29 2013-09-06 Ethicon Endo-Surgery, Inc. Compositions of microbiota and methods related thereto
BR112014024159A2 (pt) 2012-03-29 2017-06-20 Therabiome Llc Formulações de vacina oral específicas do local gastrintestinal , ativas no íleo e apêndice.
US9719144B2 (en) 2012-05-25 2017-08-01 Arizona Board Of Regents Microbiome markers and therapies for autism spectrum disorders
CN104768560A (zh) 2012-08-29 2015-07-08 加州理工学院 孤独症谱系障碍的诊断和治疗
EP4233545A3 (en) 2012-11-23 2023-10-18 Seres Therapeutics, Inc. Synergistic bacterial compositions and methods of production and use thereof
US8906668B2 (en) 2012-11-23 2014-12-09 Seres Health, Inc. Synergistic bacterial compositions and methods of production and use thereof
HK1218559A1 (zh) 2013-02-04 2017-02-24 Seres Therapeutics, Inc. 抑制致病细菌生长的配方和方法
HK1218560A1 (zh) 2013-02-04 2017-02-24 Seres Therapeutics, Inc. 组成与方法
CA2904389C (en) 2013-03-14 2018-09-18 Jerome J. Schentag Targeted gastrointestinal tract delivery of probiotic organisms and/or therapeutic agents
HK1220326A1 (zh) 2013-03-15 2017-05-05 Seres Therapeutics, Inc. 基於网络微生物组成和方法
GB201306536D0 (en) 2013-04-10 2013-05-22 Gt Biolog Ltd Polypeptide and immune modulation
PT3074027T (pt) 2013-11-25 2025-03-20 Nestle Sa Composições bacterianas sinérgicas e métodos de produção e utilização das mesmas
EP3082431A4 (en) * 2013-12-16 2017-11-15 Seres Therapeutics, Inc. Bacterial compositions and methods of use thereof for treatment of immune system disorders
EP3129035B1 (en) * 2014-04-10 2024-09-18 Riken Compositions and methods for induction of th17 cells
US20150322176A1 (en) * 2014-04-16 2015-11-12 University Of Guelph Novel polysaccharide immunogens from clostridium bolteae isolated from autistic subjects and methods and uses thereof
US20170087196A1 (en) 2014-05-19 2017-03-30 Memorial Sloan-Kettering Cancer Center Methods and compositions for reducing clostridium difficile infection
EP3212207A4 (en) 2014-10-30 2018-06-13 California Institute of Technology Compositions and methods comprising bacteria for improving behavior in neurodevelopmental disorders
AU2015339290B8 (en) 2014-10-30 2021-08-26 California Institute Of Technology Compositions and methods comprising bacteria for improving behavior in neurodevelopmental disorders
EP4529950A3 (en) 2014-10-31 2025-08-20 Pendulum Therapeutics, Inc. Methods and compositions relating to microbial treatment
DK3223835T3 (en) * 2014-11-25 2025-02-17 Memorial Sloan Kettering Cancer Center Intestinal microbiota and gvhd
MA41020A (fr) 2014-11-25 2017-10-03 Evelo Biosciences Inc Compositions probiotiques et prébiotiques, et leurs procédés d'utilisation pour la modulation du microbiome
EA202090948A1 (ru) 2014-12-23 2020-11-30 4Д Фарма Рисерч Лимитед Иммуномодуляция
CA2970234A1 (en) 2014-12-23 2016-06-30 4D Pharma Research Limited Pirin polypeptide and immune modulation
EP3242673A1 (en) * 2015-01-07 2017-11-15 Ecole Polytechnique Fédérale de Lausanne (EPFL) Gastro-intestinal biomarkers for diagnosis and therapies of proteinopathies
CN114159476A (zh) 2015-05-14 2022-03-11 克雷斯顿沃控股公司 用于粪便菌群移植的组合物以及用于制备和使用它们的方法和用于递送它们的装置
US20160339065A1 (en) 2015-05-22 2016-11-24 Arizona Board Of Regents On Behalf Of Arizona State University Methods for Treating Autism Spectrum Disorder and Associated Symptoms
MA41060B1 (fr) 2015-06-15 2019-11-29 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
PT3307288T (pt) 2015-06-15 2019-10-17 4D Pharma Res Ltd Composições compreendendo estirpes bacterianas
MA55434B1 (fr) 2015-06-15 2022-02-28 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
PT3240554T (pt) * 2015-06-15 2019-11-04 4D Pharma Res Ltd Blautia stercosis e wexlerae para uso no tratamento de doenças inflamatórias e autoimunes
MA41010B1 (fr) 2015-06-15 2020-01-31 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
EP3310367A4 (en) * 2015-06-22 2019-02-20 President and Fellows of Harvard College INDUCTION OF LAMINA-PROPRIA-REGULATORY T-CELLS
TW201713775A (zh) 2015-06-25 2017-04-16 亞斯科生物科學公司 用於自複雜的異源群集中分析微生物品系、預測及識別其機能性關係及交互作用，且依據前述選擇並合成微生物系集之方法、裝置及系統
US9938558B2 (en) 2015-06-25 2018-04-10 Ascus Biosciences, Inc. Methods, apparatuses, and systems for analyzing microorganism strains from complex heterogeneous communities, predicting and identifying functional relationships and interactions thereof, and selecting and synthesizing microbial ensembles based thereon
US10851399B2 (en) 2015-06-25 2020-12-01 Native Microbials, Inc. Methods, apparatuses, and systems for microorganism strain analysis of complex heterogeneous communities, predicting and identifying functional relationships and interactions thereof, and selecting and synthesizing microbial ensembles based thereon
AU2016321348A1 (en) * 2015-09-09 2018-04-26 Psomagen, Inc. Method and system for microbiome-derived diagnostics and therapeutics for conditions associated with thyroid health issues
EP4066846A1 (en) 2015-11-03 2022-10-05 The Brigham & Women's Hospital, Inc. Therapeutic microbiota for the treatment and/or prevention of food allergy
GB201520497D0 (en) 2015-11-20 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
BR112018010089A2 (pt) 2015-11-20 2018-11-13 4D Pharma Res Ltd composições compreendendo cepas bacterianas
GB201520631D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201520638D0 (en) * 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
PL3380108T3 (pl) * 2015-11-24 2023-03-27 Seres Therapeutics, Inc. Zaprojektowane kompozycje bakteryjne
EP3400285B1 (en) 2016-01-07 2025-10-29 Native Microbials, Inc. Methods for improving milk production by administration of microbial consortia
JP6675752B2 (ja) * 2016-02-23 2020-04-01 国立大学法人佐賀大学 腸内Ｂｌａｕｔｉａ ｃｏｃｃｏｉｄｅｓ増殖刺激剤
AU2017226831B2 (en) 2016-03-04 2018-10-04 4D Pharma Plc Compositions comprising bacterial Blautia strains for treating visceral hypersensitivity
GB201612191D0 (en) 2016-07-13 2016-08-24 4D Pharma Plc Compositions comprising bacterial strains
EP3429604A1 (en) 2016-03-14 2019-01-23 Holobiome, Inc. Modulation of the gut microbiome to treat mental disorders or diseases of the central nervous system
US11260083B2 (en) 2016-03-15 2022-03-01 The Regents Of The University Of Michigan Compositions and methods for treating and preventing graft versus host disease
US11064722B2 (en) * 2016-06-10 2021-07-20 N.V. Nutricia Risk of allergy and nutrition to reduce that risk
CA3226196A1 (en) * 2016-06-14 2017-12-21 Vedanta Biosciences, Inc. Treatment of clostridium difficile infection
US9999641B2 (en) 2016-06-14 2018-06-19 Vedanta Biosciences, Inc. Treatment of clostridium difficile infection
US20170360848A1 (en) 2016-06-15 2017-12-21 Arizona Board Of Regents On Behalf Of Arizona State University Methods for treating autism spectrum disorder and associated symptoms
US10722600B2 (en) 2016-06-17 2020-07-28 New York University Methods and compositions for treating cancer
US10849936B2 (en) 2016-07-01 2020-12-01 Regents Of The University Of Minnesota Compositions and methods for C. difficile treatment
TW201821093A (zh) 2016-07-13 2018-06-16 英商４Ｄ製藥有限公司 包含細菌菌株之組合物
US20180036352A1 (en) 2016-08-03 2018-02-08 Crestovo Holdings Llc Methods for treating ulcerative colitis
US20180185421A1 (en) * 2016-08-29 2018-07-05 Tokyo Metropolitan Government Composition comprising fecal microbiota
MX2019003447A (es) 2016-09-27 2019-08-29 Univ Texas Metodos para mejorar la terapia de bloqueo del punto de control inmune mediante la modulacion del microbioma.
WO2018071536A1 (en) 2016-10-11 2018-04-19 Crestovo Holdings Llc Compositions and methods for treating primary sclerosing cholangitis and related disorders
US11026978B2 (en) 2016-10-11 2021-06-08 Finch Therapeutics Holdings Llc Compositions and methods for treating multiple sclerosis and related disorders
US10092601B2 (en) 2016-10-11 2018-10-09 Crestovo Holdings Llc Compositions and methods for treating multiple sclerosis and related disorders
US11447738B2 (en) * 2016-10-28 2022-09-20 Vedanta Biosciences, Inc. Methods and compositions for preserving bacteria
CA3041277A1 (en) * 2016-11-01 2018-05-11 Keio University Bacterium capable of inducing th1 cells
EP3541400B1 (en) * 2016-11-18 2025-05-14 Sanford Burnham Prebys Medical Discovery Institute Gut microbiota and treatment of cancer
GB201621123D0 (en) 2016-12-12 2017-01-25 4D Pharma Plc Compositions comprising bacterial strains
WO2018107365A1 (zh) * 2016-12-13 2018-06-21 深圳华大基因研究院 粪厌氧棒杆菌(Anaerostipes caccae)及其应用
CA3122548A1 (en) 2016-12-23 2018-06-28 Keio University Compositions and methods for the induction of cd8+ t-cells
AU2017386658A1 (en) 2016-12-28 2019-07-25 Native Microbials, Inc. Methods, apparatuses, and systems for analyzing complete microorganism strains in complex heterogeneous communities, determining functional relationships and interactions thereof, and identifying and synthesizing bioreactive modificators based thereon
CA3048248A1 (en) 2016-12-28 2018-07-05 Ascus Biosciences, Inc. Methods, apparatuses, and systems for microorganism strain analysis of complex heterogeneous communities with tracer analytics, determination of functional relationships and interactions thereof, and synthesis of microbial ensembles including dosed microbial ensembles and inoculative microbial ensembles
AU2018218256A1 (en) * 2017-02-07 2019-09-26 California Institute Of Technology Modulation of gut microbiota in Huntington's disease and Rett syndrome
US10596206B1 (en) 2017-03-14 2020-03-24 Cornell University Probiotic compositions and methods of use
CA3058943C (en) 2017-04-03 2023-10-17 Gusto Global, Llc Rational design of microbial-based biotherapeutics
AU2018250206A1 (en) 2017-04-05 2019-10-31 Crestovo Holdings Llc Compositions and methods for treating parkinson's disease (PD) and related disorders
WO2018187464A1 (en) 2017-04-05 2018-10-11 Crestovo Holdings Llc Compositions and methods for treating diverticulitis and related disorders
EP3614847A4 (en) 2017-04-28 2021-09-01 Native Microbials, Inc. PROCESSES PROMOTING ENERGY AND / OR CEREAL RICH DIETS BY MEANS OF A SYNTHETIC BIO-SET OF MICROBES
WO2018213262A1 (en) * 2017-05-19 2018-11-22 Memorial Sloan-Kettering Cancer Center Methods and compositions for reducing listeria monocytogenes infection or colonization
HUE054164T2 (hu) 2017-05-22 2021-08-30 4D Pharma Res Ltd Baktériumtörzseket tartalmazó készítmények
WO2018215782A1 (en) 2017-05-24 2018-11-29 4D Pharma Research Limited Compositions comprising bacterial strain
EP3630190B1 (en) 2017-05-26 2024-02-21 Finch Therapeutics Holdings LLC Lyophilized compositions comprising fecal microbe-based therapeutic agents and methods for making and using same
JP6884889B2 (ja) 2017-06-14 2021-06-09 フォーディー ファーマ リサーチ リミテッド４Ｄ Ｐｈａｒｍａ Ｒｅｓｅａｒｃｈ Ｌｉｍｉｔｅｄ 細菌株を含む組成物
PL3600363T3 (pl) 2017-06-14 2021-06-14 4D Pharma Research Limited Kompozycje zawierające szczepy bakteryjne
SMT202000555T1 (it) 2017-06-14 2020-11-10 4D Pharma Res Limited Composizioni comprendenti un ceppo batterico del genere megaspaera e loro usi
GB201709763D0 (en) * 2017-06-19 2017-08-02 Probi Ab Biological materials and methods
JP2020529478A (ja) * 2017-08-04 2020-10-08 セカンド ゲノム インコーポレイテッド バイオ治療薬としてのロゼブリア・ホミニス（ｒｏｓｅｂｕｒｉａ ｈｏｍｉｎｉｓ）、ユーバクテリウム・エリゲンス（ｅｕｂａｃｔｅｒｉｕｍ ｅｌｉｇｅｎｓ）、およびこれらの組み合わせ
WO2019032573A1 (en) 2017-08-07 2019-02-14 Finch Therapeutics, Inc. COMPOSITIONS AND METHODS FOR MAINTAINING AND RESTORING A HEALTHY INTESTINAL BARRIER
CA3072029A1 (en) * 2017-08-07 2019-02-14 Finch Therapeutics, Inc. Compositions and methods for decolonizing antibotic-resistant bacteria in the gut
US11701394B2 (en) 2017-08-14 2023-07-18 Seres Therapeutics, Inc. Compositions and methods for treating cholestatic disease
TWI793151B (zh) 2017-08-23 2023-02-21 瑞士商諾華公司 3-(1-氧異吲哚啉-2-基)之氫吡啶-2,6-二酮衍生物及其用途
AU2018326705A1 (en) 2017-08-30 2020-03-05 Pendulum Therapeutics, Inc. Methods and compositions for treatment of microbiome-associated disorders
KR20200079292A (ko) 2017-10-30 2020-07-02 세레스 테라퓨틱스, 인코포레이티드 항생제 내성을 치료하기 위한 조성물 및 방법
EP3476396A1 (en) * 2017-10-31 2019-05-01 Institut Gustave Roussy Bacterial and cell compositions for the treatment of colorectal cancer and methods for assessing a prognosis for patients having the same
US10507221B2 (en) 2017-11-09 2019-12-17 Vedanta Biosciences, Inc. Compositions and methods for the treatment of allergy
CN111526882A (zh) * 2017-11-09 2020-08-11 韦丹塔生物科学股份有限公司 用于治疗变态反应的组合物和方法
US12053495B2 (en) 2017-12-11 2024-08-06 Vedanta Biosciences, Inc. Compositions and methods for suppressing pathogenic organisms
WO2019143883A2 (en) * 2018-01-18 2019-07-25 Vedanta Biosciences, Inc. Compositions and methods for the treatment of cancer
EP3749751A4 (en) 2018-02-09 2022-02-23 Keio University COMPOSITIONS AND METHODS FOR INDUCING CD8+ T LYMPHOCYTES
AR116109A1 (es) 2018-07-10 2021-03-31 Novartis Ag Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
EP3594321A1 (en) 2018-07-10 2020-01-15 Université catholique de Louvain Dusodibacter, a novel bacterial genus of the gastroinstestinal microbiota and uses thereof
EP3820573B1 (en) 2018-07-10 2023-08-09 Novartis AG 3-(5-hydroxy-1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and their use in the treatment of ikaros family zinc finger 2 (ikzf2)-dependent diseases
US11166990B2 (en) 2018-07-13 2021-11-09 Finch Therapeutics Holdings Llc Methods and compositions for treating ulcerative colitis
EP3823651A4 (en) 2018-07-19 2022-04-27 Pendulum Therapeutics, Inc. METHODS AND COMPOSITIONS FOR MICROBIAL TRANSPLANTATION
DE102018213030A1 (de) * 2018-08-03 2020-02-06 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Behandlung von Immunerkrankungen durch die antikörpervermittelte Neutralisierung spezifischer Darmbakterien
EP3836946A4 (en) 2018-08-17 2022-05-04 Vedanta Biosciences, Inc. METHOD OF REDUCING DYSBIosis AND RECOVERING A MICROBIOME
JP2022514145A (ja) 2018-09-27 2022-02-10 フィンチ セラピューティクス ホールディングス エルエルシー てんかんおよび関連する障害を治療するための組成物および方法
JP7444459B2 (ja) * 2018-10-04 2024-03-06 国立研究開発法人理化学研究所 ＩＬＣ２を標的としたＩｇＡ産生誘導方法
JP7737098B2 (ja) * 2018-11-05 2025-09-10 ザ・ユニバーシティ・オブ・シカゴ 感染性疾患、自己免疫疾患、およびアレルギー性疾患を治療するための方法および組成物
WO2020234746A1 (en) 2019-05-18 2020-11-26 Janssen Biotech, Inc. Materials and methods for microbiome modulation
EP3999029A4 (en) * 2019-07-17 2023-07-26 University of Utah Research Foundation CLOSTRIDIA CONSORTIA COMPOSITIONS AND METHODS OF TREATMENT OF OBESITY, METABOLIC SYNDROME AND IRRITABLE BOWEL
BR112022000875A2 (pt) 2019-07-19 2022-03-29 Finch Therapeutics Holdings Llc Métodos e produtos para tratamento de distúrbios gastrointestinais
JP2022544369A (ja) * 2019-08-14 2022-10-18 ヴァーヘニンゲン・ウニヴェルシテイト ミオ－イノシトール－プロピオネート経路を含む細菌
JP2022544616A (ja) 2019-08-16 2022-10-19 ヤンセン バイオテツク，インコーポレーテツド クロストリジウム属細菌の最適化された培養培地
EP4013852A1 (en) * 2019-08-16 2022-06-22 Janssen Biotech, Inc. Optimized culture media for clostridia bacteria
WO2021033044A1 (en) 2019-08-16 2021-02-25 Janssen Biotech, Inc. Optimized culture media for clostridia bacteria
JP2021045097A (ja) * 2019-09-20 2021-03-25 腸内フローラ移植臨床研究株式会社 腸内フローラの健康状態の診断方法及びその利用
CN115243697A (zh) * 2019-11-22 2022-10-25 未知君有限责任公司 包含细菌物种的组合物及其相关方法
US20230131960A1 (en) * 2020-03-25 2023-04-27 INSERM (Institut National de la Santé et de la Recherche Médicale) New strategy to treat and prevent diseases caused by enterobacteriae
EP3895710A1 (en) 2020-04-15 2021-10-20 DSM IP Assets B.V. Food and/or feed compositions to manage immune homeostasis
US10973908B1 (en) 2020-05-14 2021-04-13 David Gordon Bermudes Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine
WO2021234650A1 (en) * 2020-05-21 2021-11-25 Superbrewed Food, Inc. Method of treating or preventing an infection
US12011467B2 (en) 2021-05-18 2024-06-18 J. Craig Venter Institute, Inc. Bacterial formulation
CN116195742B (zh) * 2021-11-30 2024-07-09 内蒙古伊利实业集团股份有限公司 乳双歧杆菌bl-99在保护软骨中的应用
WO2023100977A1 (ja) * 2021-12-02 2023-06-08 地方独立行政法人神奈川県立産業技術総合研究所 免疫グロブリン結合タンパク質制御によるアレルギー疾患治療法および診断法の確立
CN119970806A (zh) * 2025-02-25 2025-05-13 浙江大学 多毛假解黄酮菌在制备预防、治疗和/或改善溃疡性结肠炎的药物中的应用

Family Cites Families (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3069074D1 (en) 1979-11-16 1984-10-04 Sterosynt Ltd 6-alpha-9-alpha-difluoro-16-beta-methyl-prednisolone-17,21 diesters and pharmaceutical compositions containing them
US5443826A (en) 1988-08-02 1995-08-22 Borody; Thomas J. Treatment of gastro-intestinal disorders with a fecal composition or a composition of bacteroides and E. Coli
US5599795A (en) 1994-08-19 1997-02-04 Mccann; Michael Method for treatment of idiopathic inflammatory bowel disease (IIBD)
US5700787A (en) 1994-09-02 1997-12-23 Brigham & Women's Hospital, Inc. Capsular polysaccharide immunomodulator
US6368586B1 (en) 1996-01-26 2002-04-09 Brown University Research Foundation Methods and compositions for enhancing the bioadhesive properties of polymers
JP4282763B2 (ja) 1996-03-20 2009-06-24 ザ、ユニバーシティ、オブ、ニュー、サウス、ウェイルズ 消化管内の微生物個体数の変更
US6551632B2 (en) 1997-04-01 2003-04-22 Thomas Julius Borody Methods and compositions for treating inflammatory bowel disease
ID29150A (id) 1999-01-15 2001-08-02 Entpr Ireland Cs Penggunaan lactobacillus salivarius
JP2001112485A (ja) 1999-10-19 2001-04-24 Yakult Honsha Co Ltd 腸内細菌用プライマー及び該プライマーを用いた検出方法
FR2808689B1 (fr) 2000-05-11 2004-09-03 Agronomique Inst Nat Rech Utilisation de souches acetogenes hydrogenotrophes pour la prevention ou le traitement de troubles digestifs
US20040170617A1 (en) 2000-06-05 2004-09-02 Finegold Sydney M. Method of treating diseases associated with abnormal gastrointestinal flora
AUPQ899700A0 (en) 2000-07-25 2000-08-17 Borody, Thomas Julius Probiotic recolonisation therapy
SV2003000753A (es) 2000-12-05 2003-06-16 Brigham & Womens Hospital Uso de polisacaridos zwitterionicos para la especifica modulacion del progreso inmunologico
CA2440474A1 (en) 2001-04-05 2002-10-17 Virginia Mason Research Center Methods of mhc class ii epitope mapping, detection of autoimmune t cells and antigens, and autoimmune treatment
PE20030283A1 (es) 2001-07-26 2003-05-01 Alimentary Health Ltd Cepas de lactobacillus casei
GB0220809D0 (en) * 2002-09-06 2002-10-16 Univ College Of London Immune modulator
GB0307026D0 (en) 2003-03-27 2003-04-30 Rowett Res Inst Bacterial supplement
EP1638581A2 (en) 2003-03-31 2006-03-29 The Brigham And Women's Hospital, Inc. Zwitterionic immunomodulators for the treatment of asthma and allergy
WO2004104175A2 (en) 2003-05-14 2004-12-02 University Of Georgia Research Foundation, Inc. Probiotic bacteria and methods
JP2005124495A (ja) 2003-10-24 2005-05-19 Yakult Honsha Co Ltd ヒト腸内細菌検出用プライマー
JPWO2005094886A1 (ja) 2004-03-31 2008-02-14 キリンファーマ株式会社 Ｇｐｉアンカー蛋白質アゴニストによる調節性ｔ細胞分化誘導・増殖方法およびそのための医薬組成物
US8092793B2 (en) 2004-12-15 2012-01-10 Qingdao East Sea Pharmaceuticals, Ltd. Treating inflammatory bowel disease with live bacteria
CA2599909C (en) 2005-03-03 2014-12-02 Meiji Dairies Corporation Immune function modulating agents
CU23581A1 (es) * 2005-10-28 2010-10-30 Ct Ingenieria Genetica Biotech Interferon alfa y c-ficocianina para el tratamiento de enfermedades autoinmunes, alérgicas y cáncer
WO2007092451A2 (en) 2006-02-06 2007-08-16 The Brigham And Women's Hospital, Inc. Zwitterionic polysaccharides for promotion of immune system maturation and health
DE102006062250A1 (de) 2006-12-22 2008-06-26 Roland Saur-Brosch Verwendung einer Zusammensetzung aus Mineralstoffen und/oder Vitaminen und gegebenenfalls acetogenen und/oder butyrogenen Bakterien zur oralen oder rektalen Verabreichung für die Behandlung und Vorbeugung von abdominalen Beschwerden
ES2399993T3 (es) 2007-03-02 2013-04-04 Protectimmun Gmbh Composición farmacéutica para la protección frente a alergias y enfermedades inflamatorias
EP1974743A1 (en) 2007-03-28 2008-10-01 Nestec S.A. Probiotics to Improve Gut Microbiota
CN101310730A (zh) 2007-05-27 2008-11-26 青岛东海药业有限公司 酪酸梭菌在制备防治类风湿性关节炎、强直性脊柱炎微生物制剂中的应用
JP2009084215A (ja) 2007-09-28 2009-04-23 Nippon Paper Chemicals Co Ltd 炎症性腸疾患予防・治療剤
WO2009050486A2 (en) 2007-10-19 2009-04-23 The University Of Surrey Peptide manipulators of regulatory t cell activity
US20090124573A1 (en) 2007-11-09 2009-05-14 Sarkis Mazmanian Immunomodulating compounds and related compositions and methods
CN101496819A (zh) 2008-01-31 2009-08-05 青岛东海药业有限公司 真杆菌、梭菌制剂及其应用
KR100913405B1 (ko) 2008-03-25 2009-08-21 광주과학기술원 Ｔｈ２－매개 면역 질환의 예방 또는 치료용 조성물
WO2009149149A1 (en) 2008-06-04 2009-12-10 Trustees Of Dartmouth College Prevention or treatment of immune-relevant disease by modification of microfloral populations
JP2010129134A (ja) 2008-11-28 2010-06-10 Pulstec Industrial Co Ltd ホログラム記録装置及びホログラム再生装置
CA3028277A1 (en) 2009-02-13 2010-08-19 The Regents Of The University Of California System, method and device for tissue-based diagnosis
GB0903016D0 (en) 2009-02-23 2009-04-08 Univ Gent Method for alleviating intestinal problems and novel bacterial strains therefor
EP2422200A4 (en) 2009-04-23 2013-02-27 California Inst Of Techn METHOD AND SYSTEMS FOR IDENTIFYING IMMUNOMODULATIVE SUBSTANCES
US20100311686A1 (en) 2009-06-03 2010-12-09 Kasper Lloyd H Nutraceutical composition and methods for preventing or treating multiple sclerosis
WO2011005756A1 (en) 2009-07-06 2011-01-13 Puretech Ventures, Llc Delivery of agents targeted to microbiota niches
WO2011022542A2 (en) 2009-08-19 2011-02-24 Puretech Ventures, Llc Administration of factors normally present in a microbial niche to improve health
US20120149584A1 (en) 2009-08-21 2012-06-14 Bernat Olle Methods of diagnosing and treating microbiome-associated disease using interaction network parameters
WO2011027956A2 (ko) 2009-09-04 2011-03-10 주식회사이언메딕스 그람 양성 박테리아에서 유래한 세포밖 소포체 및 이를 이용한 질병 모델
US20120276149A1 (en) * 2009-10-15 2012-11-01 Dan Littman Methods for modulating bacterial infection
EP2823822B1 (en) 2009-11-11 2016-10-12 Alimentary Health Limited A Bifidobacterium strain
BR112012020003A2 (pt) * 2010-02-10 2020-08-18 Japan Eco-Science Co., Ltd. mistura, solução de dissolução e agente farmacêutico cada um compreendendo micro-organismo termofílico
WO2011151941A1 (ja) * 2010-06-04 2011-12-08 国立大学法人東京大学 制御性ｔ細胞の増殖または集積を誘導する作用を有する組成物
EP2598155A2 (en) 2010-07-26 2013-06-05 Suomen Punainen Risti Veripalvelu Use of blood group status iii
US20120020941A1 (en) 2010-07-26 2012-01-26 Suomen Punainen Risti Veripalvelu Use of blood group status iii
ES2388662B1 (es) 2010-11-10 2014-04-11 Consejo Superior De Investigaciones Científicas (Csic) Nuevas cepas de duganella aisladas de la rizosfera de olivo silvestre y cultivado y su uso en la producción de violaceína.
US20120279149A1 (en) * 2011-05-04 2012-11-08 Sebastian George Quinn System and device for utilization of energy in buildings
US20140171339A1 (en) * 2011-06-06 2014-06-19 The University Of North Carolina At Chapel Hill Methods and kits for detecting adenomas, colorectal cancer, and uses thereof
ES2662793T3 (es) 2011-09-14 2018-04-09 Nubiyota Llc Complementos de medio y métodos para cultivar microorganismos anaerobios gastrointestinales humanos
GB201117313D0 (en) 2011-10-07 2011-11-16 Gt Biolog Ltd Bacterium for use in medicine
JP6306507B2 (ja) * 2011-12-01 2018-04-18 国立大学法人 東京大学 制御性ｔ細胞の増殖または集積を誘導するヒト由来細菌
US8906668B2 (en) 2012-11-23 2014-12-09 Seres Health, Inc. Synergistic bacterial compositions and methods of production and use thereof
KR20150103012A (ko) 2012-11-26 2015-09-09 토마스 줄리어스 보로디 분변 마이크로바이오타 복원을 위한 조성물 및 이의 제조 및 사용 방법
HK1218559A1 (zh) 2013-02-04 2017-02-24 Seres Therapeutics, Inc. 抑制致病细菌生长的配方和方法
CA2904389C (en) 2013-03-14 2018-09-18 Jerome J. Schentag Targeted gastrointestinal tract delivery of probiotic organisms and/or therapeutic agents
WO2014153194A2 (en) 2013-03-14 2014-09-25 Seres Health, Inc. Methods for pathogen detection and enrichment from materials and compositions
HK1220326A1 (zh) 2013-03-15 2017-05-05 Seres Therapeutics, Inc. 基於网络微生物组成和方法
EP3019181A4 (en) 2013-07-09 2016-09-21 Puretech Ventures Llc COMPOSITIONS WITH COMBINATIONS OF BIOACTIVE MOLECULARS DERIVED FROM MICROBOTS FOR TREATING DISEASES
EP3129035B1 (en) * 2014-04-10 2024-09-18 Riken Compositions and methods for induction of th17 cells
WO2015198105A1 (en) 2014-06-27 2015-12-30 Telefonaktiebolaget L M Ericsson (Publ) System and method for supporting time-sensitive services in a communication network
KR102318025B1 (ko) 2014-06-30 2021-10-27 샐릭스 파마슈티컬스 인코포레이티드 과민성 대장 증후군(ibs)의 재치료 방법
MA41020A (fr) * 2014-11-25 2017-10-03 Evelo Biosciences Inc Compositions probiotiques et prébiotiques, et leurs procédés d'utilisation pour la modulation du microbiome
MX385097B (es) 2015-05-30 2025-03-14 Japan Eco Science Co Ltd Probiótico o prebiótico, método para la producción del mismo, preparación microbiana, alimento saludable y medicina.
GB201520631D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
US9642281B1 (en) * 2015-12-28 2017-05-02 Martas Precision Slide Co., Ltd. Buckle set for sliding rail of industrial rackmount chassis
EP3429604A1 (en) * 2016-03-14 2019-01-23 Holobiome, Inc. Modulation of the gut microbiome to treat mental disorders or diseases of the central nervous system
US20170290889A1 (en) 2016-04-11 2017-10-12 New York University Methods and compositions for treating dysbiosis and gastrointestinal and inflammatory disorders
JP6792103B2 (ja) 2016-06-01 2020-11-25 株式会社テックコーポレーション 微細気泡水供給システム
US9999641B2 (en) 2016-06-14 2018-06-19 Vedanta Biosciences, Inc. Treatment of clostridium difficile infection
CA3041277A1 (en) 2016-11-01 2018-05-11 Keio University Bacterium capable of inducing th1 cells
CA3122548A1 (en) * 2016-12-23 2018-06-28 Keio University Compositions and methods for the induction of cd8+ t-cells
CA3072029A1 (en) 2017-08-07 2019-02-14 Finch Therapeutics, Inc. Compositions and methods for decolonizing antibotic-resistant bacteria in the gut
JP2019046634A (ja) * 2017-08-31 2019-03-22 パナソニックＩｐマネジメント株式会社 照明システム及びコントローラ
US10507221B2 (en) * 2017-11-09 2019-12-17 Vedanta Biosciences, Inc. Compositions and methods for the treatment of allergy

Also Published As

Publication number Publication date
CA2892588A1 (en) 2013-06-06
US10342832B2 (en) 2019-07-09
EP4477750A3 (en) 2025-03-26
ES2993669T3 (en) 2025-01-03
JP2015500792A (ja) 2015-01-08
EP3569690A1 (en) 2019-11-20
US20160193256A1 (en) 2016-07-07
US10238694B2 (en) 2019-03-26
CN116942833A (zh) 2023-10-27
US9642881B2 (en) 2017-05-09
US20160193257A1 (en) 2016-07-07
JP2021078504A (ja) 2021-05-27
HK1204008A1 (en) 2015-11-06
JP6306507B2 (ja) 2018-04-18
US11547732B2 (en) 2023-01-10
US20190030092A1 (en) 2019-01-31
EP4477750A2 (en) 2024-12-18
US10835559B2 (en) 2020-11-17
US20170209502A1 (en) 2017-07-27
US20210137998A1 (en) 2021-05-13
US10624933B2 (en) 2020-04-21
EP2785828A4 (en) 2015-07-29
US20170216378A1 (en) 2017-08-03
ES2994320T3 (en) 2025-01-22
CN108676774A (zh) 2018-10-19
DK3978598T3 (da) 2024-11-11
FI3569690T3 (fi) 2024-11-18
US10058578B2 (en) 2018-08-28
JP2019134703A (ja) 2019-08-15
FI3978598T3 (fi) 2024-11-12
WO2013080561A9 (en) 2013-08-08
CN104160014A (zh) 2014-11-19
EP2785828B1 (en) 2020-04-08
US10183045B2 (en) 2019-01-22
US20240000858A1 (en) 2024-01-04
US10052353B2 (en) 2018-08-21
US9649345B2 (en) 2017-05-16
CN108676774B (zh) 2023-05-09
EP2785828A1 (en) 2014-10-08
EP3569690B1 (en) 2024-08-28
JP7503273B2 (ja) 2024-06-20
US20180243348A1 (en) 2018-08-30
US20140341921A1 (en) 2014-11-20
JP7097838B2 (ja) 2022-07-08
JP6492151B2 (ja) 2019-03-27
WO2013080561A1 (en) 2013-06-06
US20190046591A1 (en) 2019-02-14
EP3978598A1 (en) 2022-04-06
JP2018039833A (ja) 2018-03-15
US20190314426A1 (en) 2019-10-17
EP3978598B1 (en) 2024-08-28
JP7165218B2 (ja) 2022-11-02
JP2023015099A (ja) 2023-01-31
JP2024129016A (ja) 2024-09-26

Similar Documents

Publication Publication Date Title
DK3978598T3 (da) Human-afledte bakterier som inducerer proliferation eller akkumulation af regulatoriske t-celler
EP2681306A4 (en) CELL CULTURE SYSTEM
PL4014982T3 (pl) Kompozycja do indukcji proliferacji lub akumulacji komórek t regulatorowych
EP2748500A4 (en) BRACKET
EP2772298A4 (en) DRY
DK3372280T3 (da) Forbedringer af eller vedrørende synsevnen
BR112013030076A2 (pt) membranas
DK2723947T3 (da) Centreringssystem
EP2789316A4 (en) CARRIER
DK2794735T3 (da) Forbedringer af eller vedrørende fiberforstærkede kompositter
BR102012007602A2 (pt) Apoio fixo
EP2744428A4 (en) TROKARTRÄGER
DE112012004186A5 (de) Glasrolle
DK3581199T3 (da) Fremgangsmåder til behandling eller reduktion af ødematøs fibrosklerotisk pannikulitis
EP2690041A4 (en) LONG MEDIUM
EP2794841A4 (en) BIOREACTOR
DK2692211T3 (da) Lysdæmperstyring af vinkellysfordeling
UA23273S (uk) Келих
EP2710032A4 (en) MODIFIED GLYCOPROTEINS
BR112014001580A2 (pt) recinto de flutuação do vidro
EE05706B1 (et) Taimekasvatuspott ja taimekasvatuspoti kassett
DK2776552T3 (da) Anordning til dyrkning af celler
EP2770577A4 (en) AIR DEPOLARIZATION CELL SYSTEM
HK40102404A (zh) 诱导调节性t细胞的增殖或积累的人源细菌
ES1074054Y (es) Estructura de soporte para paneles solares