DK3568396T3 - Hidtil ukendte amino-imidazopyridinderivater som janus kinase-inhibitorer og farmaceutisk anvendelse deraf - Google Patents
Hidtil ukendte amino-imidazopyridinderivater som janus kinase-inhibitorer og farmaceutisk anvendelse deraf Download PDFInfo
- Publication number
- DK3568396T3 DK3568396T3 DK18702412.0T DK18702412T DK3568396T3 DK 3568396 T3 DK3568396 T3 DK 3568396T3 DK 18702412 T DK18702412 T DK 18702412T DK 3568396 T3 DK3568396 T3 DK 3568396T3
- Authority
- DK
- Denmark
- Prior art keywords
- unpermanent
- janus
- inhibitors
- chinese
- amino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17151020 | 2017-01-11 | ||
| PCT/EP2018/050548 WO2018130563A1 (en) | 2017-01-11 | 2018-01-10 | Novel amino-imidazopyridine derivatives as janus kinase inhibitors and pharmaceutical use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3568396T3 true DK3568396T3 (da) | 2021-01-18 |
Family
ID=57777557
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK18702412.0T DK3568396T3 (da) | 2017-01-11 | 2018-01-10 | Hidtil ukendte amino-imidazopyridinderivater som janus kinase-inhibitorer og farmaceutisk anvendelse deraf |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US10703751B2 (da) |
| EP (1) | EP3568396B1 (da) |
| JP (1) | JP7009504B2 (da) |
| KR (1) | KR102548543B1 (da) |
| CN (1) | CN110167938A (da) |
| AU (1) | AU2018208516B2 (da) |
| BR (1) | BR112019014191A2 (da) |
| CA (1) | CA3045567A1 (da) |
| CY (1) | CY1123864T1 (da) |
| DK (1) | DK3568396T3 (da) |
| ES (1) | ES2846741T3 (da) |
| HR (1) | HRP20210095T1 (da) |
| HU (1) | HUE052720T2 (da) |
| IL (1) | IL267829B (da) |
| LT (1) | LT3568396T (da) |
| MX (1) | MX2019008331A (da) |
| MY (1) | MY195576A (da) |
| PL (1) | PL3568396T3 (da) |
| PT (1) | PT3568396T (da) |
| RS (1) | RS61317B1 (da) |
| RU (1) | RU2019125177A (da) |
| SI (1) | SI3568396T1 (da) |
| TW (1) | TWI760419B (da) |
| UA (1) | UA123972C2 (da) |
| WO (1) | WO2018130563A1 (da) |
| ZA (1) | ZA201904190B (da) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JOP20190144A1 (ar) | 2016-12-16 | 2019-06-16 | Janssen Pharmaceutica Nv | إيميدازو بيرولو بيريدين كمثبطات لعائلة jak الخاصة بإنزيمات الكيناز |
| TW202016110A (zh) | 2018-06-15 | 2020-05-01 | 比利時商健生藥品公司 | Ｊａｋ激酶家族之小分子抑制劑 |
| EP3818060B1 (en) * | 2018-07-06 | 2023-02-22 | LEO Pharma A/S | Novel amino-imidazopyrimidine derivatives as janus kinase inhibitors and pharmaceutical use thereof |
| JP7345220B2 (ja) * | 2019-08-30 | 2023-09-15 | ティーエスディー ライフ サイエンス カンパニー リミテッド | イミダゾピリジン誘導体及びこれを有効成分として含有する薬学的組成物 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2240488B1 (en) * | 2008-02-06 | 2016-11-02 | Bristol-Myers Squibb Company | Substituted imidazopyridazines useful as kinase inhibitors |
| KR20140015162A (ko) * | 2010-01-12 | 2014-02-06 | 에프. 호프만-라 로슈 아게 | 트라이사이클릭 헤테로사이클릭 화합물, 조성물 및 이의 사용 방법 |
| RU2013109143A (ru) * | 2010-08-05 | 2014-09-10 | Амджен Инк. | Бензимидазол- и азабензимидазолсодержащие соединения, которые ингибируют киназу анапластической лимфомы |
| EP2518071A1 (en) * | 2011-04-29 | 2012-10-31 | Almirall, S.A. | Imidazopyridine derivatives as PI3K inhibitors |
| EP2527344A1 (en) | 2011-05-25 | 2012-11-28 | Almirall, S.A. | Pyridin-2(1H)-one derivatives useful as medicaments for the treatment of myeloproliferative disorders, transplant rejection, immune-mediated and inflammatory diseases |
| WO2013007765A1 (en) | 2011-07-13 | 2013-01-17 | F. Hoffmann-La Roche Ag | Fused tricyclic compounds for use as inhibitors of janus kinases |
| WO2013007768A1 (en) | 2011-07-13 | 2013-01-17 | F. Hoffmann-La Roche Ag | Tricyclic heterocyclic compounds, compositions and methods of use thereof as jak inhibitors |
| UY34616A (es) | 2012-02-10 | 2013-09-30 | Galapagos Nv | Nuevo compuesto útil para el tratamiento de enfermedades degenerativas e inflamatorias. |
| NZ707495A (en) | 2012-11-01 | 2019-01-25 | Incyte Holdings Corp | Tricyclic fused thiophene derivatives as jak inhibitors |
| EP3181564B1 (en) * | 2012-11-20 | 2019-09-18 | H. Hoffnabb-La Roche Ag | Aminopyrimidine compounds as inhibitors of t790m containing egfr mutants |
| CN104098563A (zh) | 2013-04-02 | 2014-10-15 | 山东亨利医药科技有限责任公司 | Jnk抑制剂化合物 |
| TW201625643A (zh) | 2014-04-30 | 2016-07-16 | 英塞特公司 | 製備ｊａｋ１抑制劑之方法及其新形式 |
| NZ751284A (en) | 2016-10-03 | 2022-09-30 | Hangzhou Highlightll Pharmaceutical Co Ltd | Novel jak1 selective inhibitors and uses thereof |
| JOP20190144A1 (ar) | 2016-12-16 | 2019-06-16 | Janssen Pharmaceutica Nv | إيميدازو بيرولو بيريدين كمثبطات لعائلة jak الخاصة بإنزيمات الكيناز |
-
2018
- 2018-01-10 EP EP18702412.0A patent/EP3568396B1/en active Active
- 2018-01-10 CN CN201880006261.0A patent/CN110167938A/zh active Pending
- 2018-01-10 MX MX2019008331A patent/MX2019008331A/es unknown
- 2018-01-10 LT LTEP18702412.0T patent/LT3568396T/lt unknown
- 2018-01-10 UA UAA201908568A patent/UA123972C2/uk unknown
- 2018-01-10 ES ES18702412T patent/ES2846741T3/es active Active
- 2018-01-10 PL PL18702412T patent/PL3568396T3/pl unknown
- 2018-01-10 AU AU2018208516A patent/AU2018208516B2/en active Active
- 2018-01-10 RU RU2019125177A patent/RU2019125177A/ru unknown
- 2018-01-10 HU HUE18702412A patent/HUE052720T2/hu unknown
- 2018-01-10 US US16/477,249 patent/US10703751B2/en active Active
- 2018-01-10 WO PCT/EP2018/050548 patent/WO2018130563A1/en unknown
- 2018-01-10 BR BR112019014191-0A patent/BR112019014191A2/pt active Search and Examination
- 2018-01-10 KR KR1020197021697A patent/KR102548543B1/ko active IP Right Grant
- 2018-01-10 JP JP2019557681A patent/JP7009504B2/ja active Active
- 2018-01-10 PT PT187024120T patent/PT3568396T/pt unknown
- 2018-01-10 DK DK18702412.0T patent/DK3568396T3/da active
- 2018-01-10 SI SI201830191T patent/SI3568396T1/sl unknown
- 2018-01-10 RS RS20210044A patent/RS61317B1/sr unknown
- 2018-01-10 CA CA3045567A patent/CA3045567A1/en active Pending
- 2018-01-10 MY MYPI2019003964A patent/MY195576A/en unknown
- 2018-01-11 TW TW107101035A patent/TWI760419B/zh active
-
2019
- 2019-06-26 ZA ZA2019/04190A patent/ZA201904190B/en unknown
- 2019-07-03 IL IL267829A patent/IL267829B/en unknown
-
2021
- 2021-01-19 HR HRP20210095TT patent/HRP20210095T1/hr unknown
- 2021-02-01 CY CY20211100085T patent/CY1123864T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA201904190B (en) | 2020-10-28 |
| HUE052720T2 (hu) | 2021-05-28 |
| IL267829A (en) | 2019-09-26 |
| JP2020504186A (ja) | 2020-02-06 |
| AU2018208516B2 (en) | 2021-07-08 |
| PT3568396T (pt) | 2021-02-09 |
| PL3568396T3 (pl) | 2021-05-31 |
| LT3568396T (lt) | 2021-02-10 |
| UA123972C2 (uk) | 2021-06-30 |
| EP3568396A1 (en) | 2019-11-20 |
| BR112019014191A2 (pt) | 2020-02-11 |
| AU2018208516A1 (en) | 2019-07-11 |
| ES2846741T3 (es) | 2021-07-29 |
| RU2019125177A (ru) | 2021-02-15 |
| IL267829B (en) | 2022-02-01 |
| MY195576A (en) | 2023-02-02 |
| TW201829407A (zh) | 2018-08-16 |
| CA3045567A1 (en) | 2018-07-19 |
| US20190367512A1 (en) | 2019-12-05 |
| SI3568396T1 (sl) | 2021-04-30 |
| CY1123864T1 (el) | 2022-05-27 |
| RS61317B1 (sr) | 2021-02-26 |
| US10703751B2 (en) | 2020-07-07 |
| HRP20210095T1 (hr) | 2021-03-05 |
| RU2019125177A3 (da) | 2021-05-11 |
| MX2019008331A (es) | 2020-01-14 |
| WO2018130563A1 (en) | 2018-07-19 |
| KR102548543B1 (ko) | 2023-06-29 |
| JP7009504B2 (ja) | 2022-01-25 |
| EP3568396B1 (en) | 2020-11-11 |
| TWI760419B (zh) | 2022-04-11 |
| KR20190103231A (ko) | 2019-09-04 |
| CN110167938A (zh) | 2019-08-23 |
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