DK3532036T3 - Fremgangsmåde til at isolere og lyofilisere ekstracellulære vesikler - Google Patents
Fremgangsmåde til at isolere og lyofilisere ekstracellulære vesikler Download PDFInfo
- Publication number
- DK3532036T3 DK3532036T3 DK17811376.7T DK17811376T DK3532036T3 DK 3532036 T3 DK3532036 T3 DK 3532036T3 DK 17811376 T DK17811376 T DK 17811376T DK 3532036 T3 DK3532036 T3 DK 3532036T3
- Authority
- DK
- Denmark
- Prior art keywords
- lyophilizing
- isolating
- extracellular vesicles
- vesicles
- extracellular
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT102016000109148A IT201600109148A1 (it) | 2016-10-28 | 2016-10-28 | Processo per isolare e liofilizzare vescicole extracellulari |
| PCT/IB2017/056591 WO2018078524A1 (en) | 2016-10-28 | 2017-10-24 | Process for isolating and lyophilizing extracellular vesicles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3532036T3 true DK3532036T3 (da) | 2022-02-21 |
Family
ID=58228381
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK17811376.7T DK3532036T3 (da) | 2016-10-28 | 2017-10-24 | Fremgangsmåde til at isolere og lyofilisere ekstracellulære vesikler |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP3532036B1 (da) |
| DK (1) | DK3532036T3 (da) |
| ES (1) | ES2906849T3 (da) |
| HR (1) | HRP20220336T1 (da) |
| IT (1) | IT201600109148A1 (da) |
| PT (1) | PT3532036T (da) |
| SI (1) | SI3532036T1 (da) |
| WO (1) | WO2018078524A1 (da) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108633877A (zh) * | 2018-05-17 | 2018-10-12 | 广东芙金干细胞再生医学有限公司 | 一种人脐带间充质干细胞外泌体冻干粉及其制备的方法 |
| KR102649069B1 (ko) | 2018-05-31 | 2024-03-19 | 주식회사 엑소코바이오 | 줄기세포 유래의 엑소좀을 유효성분으로 포함하는 안면 홍조 개선용 조성물 |
| JP7079984B2 (ja) | 2018-07-28 | 2022-06-03 | エクソコバイオ インコーポレイテッド | エキソソームの凍結乾燥方法 |
| WO2020027467A1 (ko) * | 2018-07-30 | 2020-02-06 | 주식회사 엑소코바이오 | 줄기세포 유래 엑소좀의 동결건조제제 및 이를 유효성분으로 포함하는 항염조성물 |
| KR102163806B1 (ko) | 2018-07-30 | 2020-10-07 | 주식회사 엑소코바이오 | 줄기세포 유래의 엑소좀을 유효성분으로 포함하는 피지분비 감소용 조성물 |
| KR102161850B1 (ko) * | 2019-08-16 | 2020-10-05 | 주식회사 엑소코바이오 | 히알루론산과 동결건조된 줄기세포 유래 엑소좀의 조합을 유효성분으로 포함하는 창상 치료 또는 창상 치료 촉진용 조성물 |
| WO2021062057A1 (en) * | 2019-09-25 | 2021-04-01 | Codiak Biosciences, Inc. | Exogenous loading of exosomes via lyophilization |
| EP4054605A4 (en) * | 2019-11-04 | 2023-12-06 | Eltookhy, Omar Mohamed Salah Eldin Ahmed | METHOD FOR COATING AND DRYING EXTRACELLULAR VESICLES FROM HETEROGENEOUS STEM CELLS |
| IL272145A (en) | 2020-01-20 | 2021-07-29 | Stem Cell Medicine Ltd | Cosmetic preparations with protein concentrate from a conditioned growth medium of stem cells from adipose tissue |
| KR102215237B1 (ko) * | 2020-06-29 | 2021-02-15 | (주)지에프씨생명과학 | 세포 배양액으로부터 고수율의 엑소좀을 분리하는 방법 |
| CN111803519A (zh) * | 2020-07-13 | 2020-10-23 | 华中科技大学同济医学院附属协和医院 | 一种携载化疗药物的抗肿瘤微泡的制备方法、药剂及应用 |
| IT202100005438A1 (it) | 2021-03-09 | 2022-09-09 | Pharmaexceed S R L | Scaffold per la rigenerazione ossea e relativo metodo di fabbricazione |
| IT202100005441A1 (it) | 2021-03-09 | 2022-09-09 | Pharmaexceed S R L | Scaffold per la rigenerazione tissutale, in particolare per la rigenerazione ossea, e relativo metodo di fabbricazione |
| CN113730361B (zh) * | 2021-10-19 | 2023-06-23 | 陕西科美致尚生物科技有限公司 | 黏膜适用的类无针注射效果的外泌体制剂及制备方法 |
| CN115990261B (zh) * | 2021-10-20 | 2024-01-05 | 光武惠文生物科技(北京)有限公司 | 外泌体冻干粉针剂或外泌体液体制剂的保护剂 |
| CN114540268B (zh) * | 2022-01-05 | 2024-07-23 | 陕西微泌生物科技有限公司 | 一种基于超纯固膜技术的植物外泌体复合物的制备方法 |
| US11833224B1 (en) * | 2023-02-08 | 2023-12-05 | Leuvian Llc | Lyoprotectant compositions and uses thereof |
| CN116904362A (zh) * | 2023-07-19 | 2023-10-20 | 陕西微泌生物科技有限公司 | 一种益生菌外泌体的提取分离方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2687219A1 (en) * | 2012-07-18 | 2014-01-22 | Universität Duisburg-Essen | Use of preparations comprising exosomes derived from mesenchymal stem cells (MSCs) in the prevention and therapy of inflammatory conditions |
| CN104488850B (zh) * | 2014-11-28 | 2016-11-02 | 广州赛莱拉干细胞科技股份有限公司 | 一种制备人羊膜间充质干细胞外泌体冻干粉的方法 |
| WO2016090183A1 (en) * | 2014-12-03 | 2016-06-09 | Capricor Therapeutics, Inc. | Processes for producing stable exosome formulations |
| US20190231694A1 (en) * | 2016-10-12 | 2019-08-01 | Agency For Science, Technology And Research | Method for lyophilising an exosome |
-
2016
- 2016-10-28 IT IT102016000109148A patent/IT201600109148A1/it unknown
-
2017
- 2017-10-24 HR HRP20220336TT patent/HRP20220336T1/hr unknown
- 2017-10-24 EP EP17811376.7A patent/EP3532036B1/en active Active
- 2017-10-24 PT PT178113767T patent/PT3532036T/pt unknown
- 2017-10-24 ES ES17811376T patent/ES2906849T3/es active Active
- 2017-10-24 WO PCT/IB2017/056591 patent/WO2018078524A1/en unknown
- 2017-10-24 SI SI201731098T patent/SI3532036T1/sl unknown
- 2017-10-24 DK DK17811376.7T patent/DK3532036T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| SI3532036T1 (sl) | 2022-04-29 |
| HRP20220336T1 (hr) | 2022-05-13 |
| IT201600109148A1 (it) | 2018-04-28 |
| ES2906849T3 (es) | 2022-04-20 |
| WO2018078524A1 (en) | 2018-05-03 |
| EP3532036B1 (en) | 2021-12-29 |
| PT3532036T (pt) | 2022-03-08 |
| EP3532036A1 (en) | 2019-09-04 |
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