DK351984A - Farmaceutisk middel baseret paa valproinsyre og fremgangsmaade til fremstilling deraf - Google Patents

Farmaceutisk middel baseret paa valproinsyre og fremgangsmaade til fremstilling deraf Download PDF

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Publication number
DK351984A
DK351984A DK351984A DK351984A DK351984A DK 351984 A DK351984 A DK 351984A DK 351984 A DK351984 A DK 351984A DK 351984 A DK351984 A DK 351984A DK 351984 A DK351984 A DK 351984A
Authority
DK
Denmark
Prior art keywords
procedures
preparing
pharmaceutical agents
valproic acid
agents based
Prior art date
Application number
DK351984A
Other languages
English (en)
Other versions
DK351984D0 (da
DK161185B (da
DK161185C (da
Inventor
Daniel Aubert
Francis Blanc
Henri Desmolin
Michel Morre
Lucette Sindely
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8312376A external-priority patent/FR2549374B1/fr
Priority claimed from FR8312375A external-priority patent/FR2549370B1/fr
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of DK351984D0 publication Critical patent/DK351984D0/da
Publication of DK351984A publication Critical patent/DK351984A/da
Publication of DK161185B publication Critical patent/DK161185B/da
Application granted granted Critical
Publication of DK161185C publication Critical patent/DK161185C/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK351984A 1983-07-20 1984-07-18 Farmaceutisk middel baseret paa valproinsyre DK161185C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR8312376A FR2549374B1 (fr) 1983-07-20 1983-07-20 Compositions medicamenteuses a base d'acide valproique modifiant favorablement leur cinetique et leur procede de fabrication galenique
FR8312376 1983-07-20
FR8312375A FR2549370B1 (fr) 1983-07-20 1983-07-20 Nouvelle composition pharmaceutique a base d'acide valproique et son procede de fabrication
FR8312375 1983-07-20

Publications (4)

Publication Number Publication Date
DK351984D0 DK351984D0 (da) 1984-07-18
DK351984A true DK351984A (da) 1985-01-21
DK161185B DK161185B (da) 1991-06-10
DK161185C DK161185C (da) 1991-11-25

Family

ID=26223536

Family Applications (1)

Application Number Title Priority Date Filing Date
DK351984A DK161185C (da) 1983-07-20 1984-07-18 Farmaceutisk middel baseret paa valproinsyre

Country Status (13)

Country Link
US (1) US5017613A (da)
EP (1) EP0133110B1 (da)
JP (1) JPH0696524B2 (da)
KR (1) KR850000975A (da)
AU (1) AU563383B2 (da)
CA (1) CA1220718A (da)
DE (1) DE3469342D1 (da)
DK (1) DK161185C (da)
GR (1) GR79979B (da)
IL (1) IL72381A (da)
NZ (1) NZ208950A (da)
PH (1) PH21506A (da)
SG (1) SG52088G (da)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4913906B1 (en) * 1985-02-28 2000-06-06 Yissum Res Dev Co Controlled release dosage form of valproic acid
JPH0667828B2 (ja) * 1985-10-09 1994-08-31 日研化学株式会社 バルプロ酸ナトリウムの持続性顆粒製剤
SE8505569D0 (sv) * 1985-11-25 1985-11-25 Aco Laekemedel Ab Enteralt preparat
IT1213508B (it) * 1986-10-22 1989-12-20 Foscama Biomed Chim Farma Preparato farmaceutico a base di buflomedil cloridrato, sotto formadi compresse a rilascio controllato e relativo procedimento di preparazione.
US5169642A (en) * 1988-06-24 1992-12-08 Abbott Laboratories Sustained-release drug dosage units
US5268182A (en) * 1988-06-24 1993-12-07 Abbott Laboratories Sustained-release drug dosage units of terazosin
FR2643556B1 (fr) * 1989-02-27 1993-03-05 Sanofi Sa Composition pharmaceutique a liberation prolongee d'acide valproique
DE69327745T2 (de) * 1992-05-29 2000-09-21 Nikken Chemicals Co., Ltd. Tablette zur langsamen Freisetzung von Natriumvalproat
US6287598B1 (en) * 1993-05-28 2001-09-11 Alza Corporation Method for providing sustained antiepileptic therapy
NZ270438A (en) * 1995-02-02 1996-03-26 Bernard Charles Sherman Solid (granular) mixture of valproic acid (di-n-propyl acetic acid) and its sodium salt; pharmaceutical compositions
EP0818990A1 (en) * 1995-04-03 1998-01-21 Abbott Laboratories Homogeneous mixtures of low temperature-melting drugs and additives for controlled release
JPH09323926A (ja) * 1996-03-15 1997-12-16 Nikken Chem Co Ltd バルプロ酸ナトリウムの徐放性錠剤
FR2754177B1 (fr) * 1996-10-07 1999-08-06 Sanofi Sa Microspheres pharmaceutiques d'acide valproique pour administration orale
DE19840152A1 (de) * 1998-09-03 2000-03-09 Dresden Arzneimittel Calciumvalproat enthaltende pharmazeutische Zusammensetzungen mit retardierter Wirkstoff-Freisetzung, Verfahren zu deren Herstellung und deren Verwendung
AR020343A1 (es) * 1998-11-24 2002-05-08 Steigerwald Arzlneimittelwerk Metodo para producir farmacos que contienen extractos de plantas en una forma solida de aplicacion.
US20020031549A1 (en) * 1998-12-18 2002-03-14 Yihong Qiu Controlled release formulation of divalproex sodium
US6528090B2 (en) 1998-12-18 2003-03-04 Abbott Laboratories Controlled release formulation of divalproex sodium
US6419953B1 (en) * 1998-12-18 2002-07-16 Abbott Laboratories Controlled release formulation of divalproex sodium
US6713086B2 (en) 1998-12-18 2004-03-30 Abbott Laboratories Controlled release formulation of divalproex sodium
US6511678B2 (en) 1998-12-18 2003-01-28 Abbott Laboratories Controlled release formulation of divalproex sodium
JP5420126B2 (ja) * 1999-02-04 2014-02-19 アボット・ラボラトリーズ ｐＨ非依存延長放出性医薬組成物
US6150410A (en) * 1999-02-04 2000-11-21 Abbott Laboratories pH independent extended release pharmaceutical formulation
DE50008920D1 (de) 1999-11-02 2005-01-13 Cilag Ag Schaffhausen Verfahren zur herstellung von verbindungen der valproinsäure
US20020132010A1 (en) * 2000-12-22 2002-09-19 Yihong Qui Divalproex sodium dosage forms and a process for their production
US20020143058A1 (en) 2001-01-24 2002-10-03 Taro Pharmaceutical Inductries Ltd. Process for preparing non-hygroscopic sodium valproate composition
US20040105886A1 (en) * 2001-02-16 2004-06-03 Chih-Ming Chen Divalproex sodium tablets
US6610326B2 (en) 2001-02-16 2003-08-26 Andrx Corporation Divalproex sodium tablets
US20040037880A1 (en) * 2002-06-07 2004-02-26 Pratik Kumar Extended release formulation of divalproex sodium
CN1829804A (zh) 2002-11-22 2006-09-06 约翰斯·霍普金斯大学 治疗认知功能障碍的靶位
US7713550B2 (en) * 2004-06-15 2010-05-11 Andrx Corporation Controlled release sodium valproate formulation
US20050276848A1 (en) * 2004-06-15 2005-12-15 Nilobon Podhipleux Sustained release neutralized divalproex sodium
US20050276849A1 (en) * 2004-06-15 2005-12-15 Nilobon Podhipleux Sustained release dosage forms
US20060160852A1 (en) * 2004-12-27 2006-07-20 Eisai Co. Ltd. Composition containing anti-dementia drug
US20060280789A1 (en) * 2004-12-27 2006-12-14 Eisai Research Institute Sustained release formulations
US20060246003A1 (en) * 2004-12-27 2006-11-02 Eisai Co. Ltd. Composition containing anti-dementia drug
US20090208579A1 (en) * 2004-12-27 2009-08-20 Eisai R & D Management Co., Ltd. Matrix Type Sustained-Release Preparation Containing Basic Drug or Salt Thereof, and Method for Manufacturing the Same
US20060159753A1 (en) * 2004-12-27 2006-07-20 Eisai Co. Ltd. Matrix type sustained-release preparation containing basic drug or salt thereof
US20070129402A1 (en) * 2004-12-27 2007-06-07 Eisai Research Institute Sustained release formulations
JP2008525313A (ja) * 2004-12-27 2008-07-17 エーザイ・アール・アンド・ディー・マネジメント株式会社 抗痴呆薬の安定化方法
HK1081802A2 (en) * 2005-09-09 2006-05-19 Jacky Lam Chi Sum Intelligent crossroad
US20070082046A1 (en) * 2005-10-11 2007-04-12 Banner Pharmacaps, Inc. Enteric valproic acid
EA033130B1 (ru) 2008-10-16 2019-08-30 Дзе Джонс Хопкинс Юниверсити Способы и композиции для улучшения когнитивной функции
US20110212928A1 (en) * 2010-02-09 2011-09-01 The Johns Hopkins University Methods and compositions for improving cognitive function
KR101733189B1 (ko) 2010-10-06 2017-05-08 (주)아모레퍼시픽 손톱 또는 발톱 성장 촉진용 조성물
GB201020133D0 (en) * 2010-11-26 2011-01-12 Royal Holloway & Bedford New College Therapeutic use of compounds
EP2919788A4 (en) 2012-11-14 2016-05-25 Univ Johns Hopkins METHODS AND COMPOSITIONS FOR THE TREATMENT OF SCHIZOPHRENIA
US10806717B2 (en) 2013-03-15 2020-10-20 The Johns Hopkins University Methods and compositions for improving cognitive function
ES2881081T3 (es) 2013-03-15 2021-11-26 Agenebio Inc Procedimientos y composiciones para mejorar la función cognitiva
KR20170015315A (ko) * 2014-06-10 2017-02-08 라이온 가부시키가이샤 청주 효모를 함유하는 정제
JP6899043B2 (ja) 2015-05-22 2021-07-07 エージンバイオ， インコーポレイテッド レベチラセタムの持続放出性医薬組成物
CN108578678A (zh) * 2018-03-13 2018-09-28 孟斯琴 一种抗癫痫药物组合物及其制备方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB760114A (en) * 1953-06-19 1956-10-31 Chimie Atomistique Improvements in and relating to compositions for lowering the cholesterol level in the blood serum
FR2442M (fr) * 1962-10-17 1964-04-06 Henry Eugene L'acide dipropylacétique et ses dérivés en tant que nouveuax médicaments dépresseurs du systeme nerveux central.
FR2077918B1 (da) * 1970-02-24 1973-04-06 Berthier Laboratoires
NL7115745A (en) * 1971-11-16 1973-05-18 Dipropylacetic acid derivs - as anticonvulsants, tranquillizers muscle relaxants, antipyretics and diuretics
FR2383907A1 (fr) * 1977-03-15 1978-10-13 Labaz Procede de preparation de derives de l'acide acetique et derives obtenus par ce procede
IL59407A (en) * 1979-03-06 1983-12-30 Sanofi Sa Di-n-propylacetic acid diesters of glycerol,their preparation and pharmaceutical compositions containing them
US4654370A (en) * 1979-03-12 1987-03-31 Abbott Laboratories Glyceryl valproates
IT1121282B (it) * 1979-06-08 1986-04-02 Medea Res Srl Composto ad attivita'antiepilettica e anticonvulsivante,processo per la sua preparazione e composizioni farmaceutiche relative
WO1981000562A1 (en) * 1979-08-20 1981-03-05 Abbott Lab Mixed salt of valproic acid
US4301176A (en) * 1980-08-18 1981-11-17 Warner-Lambert Company Method of administering calcium valproate
LU83729A1 (fr) * 1981-11-04 1983-09-01 Galephar Sels d'acide valproique,leur preparation et leur utilisation
US4369172A (en) * 1981-12-18 1983-01-18 Forest Laboratories Inc. Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose
FR2547499A1 (fr) * 1983-06-15 1984-12-21 Opochimiotherapie Lab Medicaments contenant du dipropylacetate de calcium
FR2549371B1 (fr) * 1983-07-20 1985-09-13 Sanofi Sa Nouvelle composition pharmaceutique contenant de l'acide valproique ou un de ses sels
US4558070A (en) * 1983-10-26 1985-12-10 Abbott Laboratories Acid salts of valproic acid
IE58110B1 (en) * 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation
US4913906B1 (en) * 1985-02-28 2000-06-06 Yissum Res Dev Co Controlled release dosage form of valproic acid
DE3709230A1 (de) * 1987-03-20 1988-10-06 Desitin Arzneimittel Gmbh Neues calciumsalz der valproinsaeure

Also Published As

Publication number Publication date
IL72381A (en) 1988-03-31
PH21506A (en) 1987-11-10
US5017613A (en) 1991-05-21
EP0133110B1 (fr) 1988-02-17
DK351984D0 (da) 1984-07-18
SG52088G (en) 1989-01-27
DK161185B (da) 1991-06-10
GR79979B (da) 1984-10-31
AU563383B2 (en) 1987-07-09
IL72381A0 (en) 1984-11-30
CA1220718A (fr) 1987-04-21
AU3075584A (en) 1985-01-24
KR850000975A (ko) 1985-03-14
JPH0696524B2 (ja) 1994-11-30
NZ208950A (en) 1987-09-30
JPS6041610A (ja) 1985-03-05
DK161185C (da) 1991-11-25
EP0133110A1 (fr) 1985-02-13
DE3469342D1 (en) 1988-03-24

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