GB760114A - Improvements in and relating to compositions for lowering the cholesterol level in the blood serum - Google Patents
Improvements in and relating to compositions for lowering the cholesterol level in the blood serumInfo
- Publication number
- GB760114A GB760114A GB1707753A GB1707753A GB760114A GB 760114 A GB760114 A GB 760114A GB 1707753 A GB1707753 A GB 1707753A GB 1707753 A GB1707753 A GB 1707753A GB 760114 A GB760114 A GB 760114A
- Authority
- GB
- United Kingdom
- Prior art keywords
- group
- alkyl
- lowering
- sodium
- blood serum
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
- C07C53/126—Acids containing more than four carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
- C07C53/126—Acids containing more than four carbon atoms
- C07C53/128—Acids containing more than four carbon atoms the carboxylic group being bound to a carbon atom bound to at least two other carbon atoms, e.g. neo-acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
A composition for lowering the cholesterol level in the blood serum comprises a compound of formula <FORM:0760114/VI/1> where R represents an alkyl or aryl radical, R1 represents hydrogen or an alkyl radical. R2 represents an alkyl or alkylene radical, m is 0 or 1 and X is an OH group, a group OMn where M is an alkali metal, an alkaline earth metal, aluminium or magnesium and n such that nx (valency of M) = 1, and OB group, B being the cation of an organic base, or an NH2 group, together with a therapeutically inactive and non-toxic solid or semi-solid vehicle, an isotonic solution or a fatty oil. Specified compounds include sodium phenylethyl acetate, phenylethylacetamide, sodium phenyl methylacetate, and sodium phenylethyl propionate. The active compound may be mixed with starch, magnesium stearate or talc to form tablets, with cocoa butter to form suppositories or isotonic solutions or fatty oils for parenteral injection. In an example tablets are prepared from a composition comprising phenylethylacetamide, starch, magnesium stearate and talc.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1707753A GB760114A (en) | 1953-06-19 | 1953-06-19 | Improvements in and relating to compositions for lowering the cholesterol level in the blood serum |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1707753A GB760114A (en) | 1953-06-19 | 1953-06-19 | Improvements in and relating to compositions for lowering the cholesterol level in the blood serum |
Publications (1)
Publication Number | Publication Date |
---|---|
GB760114A true GB760114A (en) | 1956-10-31 |
Family
ID=10088836
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1707753A Expired GB760114A (en) | 1953-06-19 | 1953-06-19 | Improvements in and relating to compositions for lowering the cholesterol level in the blood serum |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB760114A (en) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3061634A (en) * | 1959-02-17 | 1962-10-30 | Francesco Angelini | Halo and phenyl substituted phenyl lower alkyl carbinol mono esters of succinic, glutaric, and maleic acids |
FR2209555A1 (en) * | 1972-12-11 | 1974-07-05 | Labaz | |
US3969508A (en) * | 1974-11-27 | 1976-07-13 | Smithkline Corporation | Lowering the concentration of plasma triglycerides |
EP0005422A2 (en) * | 1978-05-03 | 1979-11-14 | Sanofi S.A. | Derivatives of omega-dialkylalkanoic acids, processes for their preparation and their therapeutical use |
US4246282A (en) | 1979-06-07 | 1981-01-20 | Labaz | ω-Dialkylalkanoic acid derivatives used to induce antianoxic activity |
US5017613A (en) * | 1983-07-20 | 1991-05-21 | Sanofi, S. A. | Valproic acid preparations |
-
1953
- 1953-06-19 GB GB1707753A patent/GB760114A/en not_active Expired
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3061634A (en) * | 1959-02-17 | 1962-10-30 | Francesco Angelini | Halo and phenyl substituted phenyl lower alkyl carbinol mono esters of succinic, glutaric, and maleic acids |
FR2209555A1 (en) * | 1972-12-11 | 1974-07-05 | Labaz | |
US3969508A (en) * | 1974-11-27 | 1976-07-13 | Smithkline Corporation | Lowering the concentration of plasma triglycerides |
EP0005422A2 (en) * | 1978-05-03 | 1979-11-14 | Sanofi S.A. | Derivatives of omega-dialkylalkanoic acids, processes for their preparation and their therapeutical use |
EP0005422A3 (en) * | 1978-05-03 | 1979-12-12 | Sanofi, Societe Anonyme | Derivatives of omega-dialkylalkanoic acids, processes for their preparation and their therapeutical use |
US4246282A (en) | 1979-06-07 | 1981-01-20 | Labaz | ω-Dialkylalkanoic acid derivatives used to induce antianoxic activity |
US5017613A (en) * | 1983-07-20 | 1991-05-21 | Sanofi, S. A. | Valproic acid preparations |
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