DK3484467T3 - Kombination af rene 5-ht6-receptorantagonister med acetylcholinesterasehæmmere - Google Patents

Kombination af rene 5-ht6-receptorantagonister med acetylcholinesterasehæmmere Download PDF

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Publication number
DK3484467T3
DK3484467T3 DK16766622.1T DK16766622T DK3484467T3 DK 3484467 T3 DK3484467 T3 DK 3484467T3 DK 16766622 T DK16766622 T DK 16766622T DK 3484467 T3 DK3484467 T3 DK 3484467T3
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DK
Denmark
Prior art keywords
pure
combination
receptor antagonists
acetyl choline
inhibitors
Prior art date
Application number
DK16766622.1T
Other languages
English (en)
Inventor
Ramakrishna Nirogi
Anil Karbhari Shinde
Pradeep Jayarajan
Gopinadh Bhyrapuneni
Ramasastri Kambhampati
Venkateswarlu Jasti
Original Assignee
Suven Life Sciences Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suven Life Sciences Ltd filed Critical Suven Life Sciences Ltd
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Publication of DK3484467T3 publication Critical patent/DK3484467T3/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • A61K31/305Mercury compounds
    • A61K31/31Mercury compounds containing nitrogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Emergency Medicine (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Steroid Compounds (AREA)
DK16766622.1T 2016-05-18 2016-08-03 Kombination af rene 5-ht6-receptorantagonister med acetylcholinesterasehæmmere DK3484467T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN201641017205 2016-05-18
PCT/IB2016/054673 WO2017199071A1 (en) 2016-05-18 2016-08-03 Combination of pure 5-ht6 receptor antagonists with acetylcholinesterase inhibitors

Publications (1)

Publication Number Publication Date
DK3484467T3 true DK3484467T3 (da) 2020-06-08

Family

ID=56940098

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16766622.1T DK3484467T3 (da) 2016-05-18 2016-08-03 Kombination af rene 5-ht6-receptorantagonister med acetylcholinesterasehæmmere

Country Status (28)

Country Link
US (1) US11458135B2 (da)
EP (1) EP3484467B1 (da)
JP (1) JP6606299B2 (da)
KR (1) KR102015484B1 (da)
CN (2) CN114642667A (da)
AU (1) AU2016407427B2 (da)
BR (1) BR112018073419A2 (da)
CA (1) CA3023819C (da)
CY (1) CY1123013T1 (da)
DK (1) DK3484467T3 (da)
EA (1) EA036347B1 (da)
ES (1) ES2796181T3 (da)
HR (1) HRP20200872T1 (da)
HU (1) HUE050819T2 (da)
IL (1) IL262921B (da)
LT (1) LT3484467T (da)
MA (1) MA45639B1 (da)
MD (1) MD3484467T2 (da)
ME (1) ME03731B (da)
MX (1) MX2018014185A (da)
NZ (1) NZ748280A (da)
PL (1) PL3484467T3 (da)
PT (1) PT3484467T (da)
RS (1) RS60422B1 (da)
SG (1) SG11201809856SA (da)
SI (1) SI3484467T1 (da)
WO (1) WO2017199071A1 (da)
ZA (1) ZA201807468B (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111084768A (zh) * 2018-10-24 2020-05-01 中国科学院昆明动物研究所 吉非罗齐及其衍生物用于治疗和/或预防神经退行性疾病的用途
CN111084776A (zh) * 2018-10-24 2020-05-01 中国科学院昆明动物研究所 匹立尼酸及其衍生物用于治疗和/或预防神经退行性疾病的用途
JP7556031B2 (ja) * 2019-12-02 2024-09-25 スヴェン・ライフ・サイエンシーズ・リミテッド 認知症患者の行動心理学的症状の治療
BR112022010540A2 (pt) 2019-12-02 2022-08-16 Suven Life Sciences Ltd Métodos para tratar sintomas comportamentais e psicológicos em pacientes com demência

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1581492T3 (da) * 2002-11-28 2008-11-10 Suven Life Sciences Ltd N-arylsulfonyl-3-substituerede indoler med serotoninreceptoraffinitet, fremgangsmåde til fremstilling heraf og en farmaceutisk sammensætning indeholdende disse
PE20071143A1 (es) * 2006-01-13 2008-01-20 Wyeth Corp Composicion farmaceutica que comprende un inhibidor de acetilcolinesterasa y un antagonista 5-hidroxitriptamina-6
MX2008015996A (es) * 2006-06-23 2009-01-20 Esteve Labor Dr Combinacion de un inhibidor de la colinesterasa y un compuesto con afinidad por el receptor 5-ht6.
AR061637A1 (es) 2006-06-26 2008-09-10 Epix Delaware Inc Composiciones y metodos de tratamiento de trastornos del snc
JO3459B1 (ar) 2012-09-09 2020-07-05 H Lundbeck As تركيبات صيدلانية لعلاج مرض الزهايمر
ME02843B (me) 2013-12-02 2018-01-20 Suven Life Sciences Ltd Proces za masovnu proizvodnju monohidrata 1- [(2-bromofenil)sulfonil]-5-metoksi-3-[( 4- metil- 1-piperazinil)metil]-1h-indol dimezilata

Also Published As

Publication number Publication date
IL262921B (en) 2020-05-31
MX2018014185A (es) 2019-02-25
LT3484467T (lt) 2020-07-10
PT3484467T (pt) 2020-06-16
KR102015484B1 (ko) 2019-08-28
US20190125743A1 (en) 2019-05-02
SI3484467T1 (sl) 2020-10-30
ZA201807468B (en) 2020-02-26
RS60422B1 (sr) 2020-07-31
PL3484467T3 (pl) 2020-08-24
US11458135B2 (en) 2022-10-04
AU2016407427B2 (en) 2019-11-21
CN109069468A (zh) 2018-12-21
BR112018073419A2 (pt) 2019-03-19
ME03731B (me) 2021-01-20
EA201892529A1 (ru) 2019-03-29
CY1123013T1 (el) 2021-10-29
CN114642667A (zh) 2022-06-21
JP6606299B2 (ja) 2019-11-13
CA3023819A1 (en) 2017-11-23
HRP20200872T1 (hr) 2020-11-27
MD3484467T2 (ro) 2020-06-30
HUE050819T2 (hu) 2021-01-28
EA036347B1 (ru) 2020-10-29
IL262921A (en) 2018-12-31
EP3484467B1 (en) 2020-04-29
WO2017199071A1 (en) 2017-11-23
SG11201809856SA (en) 2018-12-28
EP3484467A1 (en) 2019-05-22
CA3023819C (en) 2019-10-22
JP2019516699A (ja) 2019-06-20
MA45639B1 (fr) 2020-06-30
KR20190002700A (ko) 2019-01-08
NZ748280A (en) 2020-07-31
AU2016407427A1 (en) 2018-11-22
ES2796181T3 (es) 2020-11-26

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