DK3480213T3 - Syntac-polypeptider og anvendelser deraf - Google Patents
Syntac-polypeptider og anvendelser deraf Download PDFInfo
- Publication number
- DK3480213T3 DK3480213T3 DK18212801.7T DK18212801T DK3480213T3 DK 3480213 T3 DK3480213 T3 DK 3480213T3 DK 18212801 T DK18212801 T DK 18212801T DK 3480213 T3 DK3480213 T3 DK 3480213T3
- Authority
- DK
- Denmark
- Prior art keywords
- applications
- syntac polypeptides
- syntac
- polypeptides
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70539—MHC-molecules, e.g. HLA-molecules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Transplantation (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462013715P | 2014-06-18 | 2014-06-18 | |
| EP15809277.5A EP3157552B1 (en) | 2014-06-18 | 2015-06-15 | Syntac polypeptides and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3480213T3 true DK3480213T3 (da) | 2020-02-17 |
Family
ID=54936224
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK18212801.7T DK3480213T3 (da) | 2014-06-18 | 2015-06-15 | Syntac-polypeptider og anvendelser deraf |
| DK15809277.5T DK3157552T3 (da) | 2014-06-18 | 2015-06-15 | Syntac-polypeptider og anvendelser deraf |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK15809277.5T DK3157552T3 (da) | 2014-06-18 | 2015-06-15 | Syntac-polypeptider og anvendelser deraf |
Country Status (15)
| Country | Link |
|---|---|
| US (5) | US20170058015A1 (cg-RX-API-DMAC7.html) |
| EP (3) | EP3157552B1 (cg-RX-API-DMAC7.html) |
| JP (4) | JP6652932B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR102252119B1 (cg-RX-API-DMAC7.html) |
| CN (3) | CN106456733B (cg-RX-API-DMAC7.html) |
| AU (3) | AU2015277460B2 (cg-RX-API-DMAC7.html) |
| DK (2) | DK3480213T3 (cg-RX-API-DMAC7.html) |
| ES (2) | ES2767259T3 (cg-RX-API-DMAC7.html) |
| HU (2) | HUE047255T2 (cg-RX-API-DMAC7.html) |
| IL (3) | IL248979B (cg-RX-API-DMAC7.html) |
| PL (2) | PL3157552T3 (cg-RX-API-DMAC7.html) |
| PT (2) | PT3157552T (cg-RX-API-DMAC7.html) |
| SG (2) | SG10202006338UA (cg-RX-API-DMAC7.html) |
| TW (3) | TWI696633B (cg-RX-API-DMAC7.html) |
| WO (1) | WO2015195531A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016500255A (ja) | 2012-12-11 | 2016-01-12 | アルバート アインシュタイン カレッジ オブ メディシン オブ イエシバ ユニバーシティ | ハイスループットなレセプター:リガンド同定の方法 |
| JP2019516665A (ja) * | 2016-03-02 | 2019-06-20 | キュー バイオファーマ, インコーポレイテッド | T細胞調節多量体ポリペプチド及びその使用方法 |
| US20190046648A1 (en) * | 2016-03-03 | 2019-02-14 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides and methods of use thereof |
| US11505591B2 (en) | 2016-05-18 | 2022-11-22 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides and methods of use thereof |
| KR20190044029A (ko) * | 2016-05-18 | 2019-04-29 | 알버트 아인슈타인 컬리지 오브 메디슨, 인크. | 변이체 pd-l1 폴리펩타이드, t-세포 조절 다량체 폴리펩타이드 및 이들의 사용 방법 |
| WO2018027252A1 (en) * | 2016-08-11 | 2018-02-15 | The Council Of The Queensland Institute Of Medical Research | Immune-modulating compounds |
| DK3558339T5 (da) | 2016-12-22 | 2024-09-02 | Cue Biopharma Inc | T-celle-modulerende multimere polypeptider og fremgangsmåder til anvendelse deraf |
| EP3565829A4 (en) * | 2017-01-09 | 2021-01-27 | Cue Biopharma, Inc. | T-CELL-MODULATING MULTIMERIC POLYPEPTIDES AND METHOD OF USING THEREOF |
| US20200010528A1 (en) * | 2017-03-15 | 2020-01-09 | Cue Biopharma, Inc. | Methods for modulating an immune response |
| US11407806B2 (en) * | 2017-04-06 | 2022-08-09 | Albert Einstein College Of Medicine | Precision activation of HIV-specific CTLS to eliminate reactivated latent T cells |
| EP3638258A4 (en) * | 2017-06-12 | 2021-09-08 | Sinai Health System | ALLOGRAFT TOLERANCE WITHOUT REQUIRING SYSTEMIC IMMUNE SUPPRESSION |
| CN107266581B (zh) * | 2017-06-13 | 2021-07-09 | 四川大学 | 藏猪il-12重组质粒增强pcv2疫苗免疫佐剂的制备方法及应用 |
| WO2019030581A1 (en) * | 2017-08-10 | 2019-02-14 | Grifols Diagnostic Solutions Inc. | COMPOSITIONS, METHODS AND / OR KITS COMPRISING AN EXTRACELLULAR DOMAIN OF RECOMBINANT HUMAN CD38 |
| KR20200064083A (ko) * | 2017-09-07 | 2020-06-05 | 큐 바이오파마, 인크. | 항원-제시 폴리펩티드 및 이의 사용 방법 |
| IL272085B2 (en) * | 2017-09-07 | 2023-03-01 | Cue Biopharma Inc | Multimeric t-cell modulatory polypeptides and methods of use thereof |
| CN111315768A (zh) * | 2017-09-07 | 2020-06-19 | 库尔生物制药有限公司 | 具有缀合位点的t细胞调节性多聚体多肽及其使用方法 |
| TW201925235A (zh) * | 2017-09-07 | 2019-07-01 | 美商信號生物製藥公司 | 具有化學結合位點之抗原呈現多肽及其使用方法 |
| CN110167959A (zh) * | 2017-11-30 | 2019-08-23 | 盖立复诊断解决方案公司 | 用于监测对免疫检查点抑制剂pd1和pd-l1的抗体治疗的免疫测定和工程化蛋白 |
| CN111886241A (zh) | 2018-01-09 | 2020-11-03 | 库尔生物制药有限公司 | 多聚体t细胞调节多肽及其使用方法 |
| HUE070158T2 (hu) | 2018-03-24 | 2025-05-28 | Regeneron Pharma | Genetikailag módosított egerek vagy patkányok peptid-mhc komplexek elleni terápiás antitestek létrehozásra, ezek elõállítására szolgáló módszerek, valamint alkalmazásuk |
| US20220047710A1 (en) * | 2018-09-12 | 2022-02-17 | Washington University | Single chain constructs |
| US20220016181A1 (en) * | 2018-12-13 | 2022-01-20 | Sinai Health System | Immunomodulatory cells and uses thereof |
| TWI856047B (zh) * | 2018-12-19 | 2024-09-21 | 美商信號生物製藥公司 | 多聚體t細胞調節多肽及其使用方法 |
| AU2019401183A1 (en) * | 2018-12-19 | 2021-08-12 | Cue Biopharma, Inc. | Multimeric T-cell modulatory polypeptides and methods of use thereof |
| EP3897690A4 (en) * | 2018-12-19 | 2022-09-28 | Cue Biopharma, Inc. | T LYMPHOCYTE MODULATOR MULTIMERIC POLYPEPTIDES HAVING CONJUGATION SITES AND METHODS OF USE THEREOF |
| EP3935080A4 (en) * | 2019-03-06 | 2023-04-05 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides and methods of use thereof |
| WO2020180501A1 (en) * | 2019-03-06 | 2020-09-10 | Cue Biopharma, Inc. | T-cell modulatory antigen-presenting polypeptides and methods of use thereof |
| EP3976084A4 (en) * | 2019-05-29 | 2023-06-21 | Cue Biopharma, Inc. | MULTIMERIC T LYMPHOCYTE MODULATING POLYPEPTIDES AND METHODS OF USE THEREOF |
| EP3986448A4 (en) * | 2019-06-19 | 2023-07-12 | Cue Biopharma, Inc. | MULTIMERIC T-CELL-MODULATING POLYPEPTIDES AND METHODS OF USE THEREOF |
| CA3146591A1 (en) * | 2019-09-20 | 2021-03-25 | Ronald D. Seidel Iii | T-cell modulatory polypeptides and methods of use thereof |
| JP2023500574A (ja) * | 2019-10-23 | 2023-01-10 | キュー バイオファーマ, インコーポレイテッド | T細胞調節性キメラ分子及びその使用方法 |
| WO2021127495A1 (en) | 2019-12-20 | 2021-06-24 | Regeneron Pharmaceuticals, Inc. | Novel il2 agonists and methods of use thereof |
| US20230076204A1 (en) * | 2020-02-18 | 2023-03-09 | Institute For Systems Biology | Single chain trimer mhc class ii nucleic acids and proteins and methods of use |
| EP4106790A4 (en) * | 2020-02-21 | 2024-02-21 | 3T Biosciences, Inc. | YEAST DISPLAY LIBRARIES, RELATED COMPOSITIONS AND RELATED METHODS OF USE |
| US20230126784A1 (en) * | 2020-03-06 | 2023-04-27 | Albert Einstein College Of Medicine | A method to generate chimeric antigen receptor (car) t-cells (car-t cells) from pathogen-specific cytotoxic lymphocytes to enable the subsequent in vivo modulation of their functional activity |
| IL296209A (en) | 2020-05-12 | 2022-11-01 | Cue Biopharma Inc | Multimeric t-cell modulatory polypeptides and methods of using them |
| CA3178427A1 (en) * | 2020-05-12 | 2021-11-18 | Lg Chem, Ltd. | Multimeric t-cell modulatory polypeptides and methods of use thereof |
| WO2022056015A1 (en) * | 2020-09-09 | 2022-03-17 | Cue Biopharma, Inc. | Mhc class ii t-cell modulatory multimeric polypeptides and methods of use thereof |
| EP4211149A4 (en) | 2020-09-09 | 2024-10-09 | Cue Biopharma, Inc. | MULTIMERIC POLYPEPTIDES MODULATING MHC CLASS II T CELLS FOR THE TREATMENT OF TYPE 1 DIABETES MELLITUS (T1D) AND METHODS OF USE THEREOF |
| CN112779224A (zh) * | 2021-01-27 | 2021-05-11 | 河南省华隆生物技术有限公司 | 一种表达细胞因子组合物的nk滋养层细胞及其制备方法和应用 |
| CN112725284A (zh) * | 2021-01-27 | 2021-04-30 | 河南省华隆生物技术有限公司 | 一种nk滋养层细胞及其应用 |
| CN112725273A (zh) * | 2021-01-27 | 2021-04-30 | 河南省华隆生物技术有限公司 | 一种nk细胞及其制备方法和应用 |
| CN112852744A (zh) * | 2021-01-27 | 2021-05-28 | 河南省华隆生物技术有限公司 | 一种nk滋养层细胞及其制备方法和应用 |
| CA3209361A1 (en) * | 2021-03-19 | 2022-09-22 | Ronald D. Seidel Iii | T-cell modulatory polypeptides and methods of use thereof |
| WO2022216974A1 (en) * | 2021-04-07 | 2022-10-13 | Repertoire Immune Medicines, Inc. | Peptide-mhc-immunoglobulin multimers and methods of use thereof |
| CN117730151A (zh) * | 2021-05-07 | 2024-03-19 | 系统生物学研究所 | 单链三聚体mhcⅰ类核酸和蛋白质以及使用方法 |
| AU2022331241A1 (en) | 2021-08-16 | 2024-03-28 | Regeneron Pharmaceuticals, Inc. | Novel il27 receptor agonists and methods of use thereof |
| US20240376464A1 (en) * | 2021-08-20 | 2024-11-14 | 3T Biosciences, Inc. | PEPTIDE-HLA-B*35 Libraries, Associated Compositions, and Associated Methods of Use |
| US20250059254A1 (en) * | 2022-01-03 | 2025-02-20 | Aarhus Universitet | Proteinaceous compound for generating specific cytotoxic t-cell effect |
| US20250271443A1 (en) * | 2022-04-21 | 2025-08-28 | Institute For Systems Biology | Soluble single-chain dimers from cleavable single chain trimers |
| KR20250035053A (ko) | 2022-06-07 | 2025-03-11 | 리제너론 파아마슈티컬스, 인크. | T 세포 활성을 조절하기 위한 다중특이적 분자 및 이의 용도 |
| EP4536836A1 (en) | 2022-06-07 | 2025-04-16 | Regeneron Pharmaceuticals, Inc. | Pseudotyped viral particles for targeting tcr-expressing cells |
| WO2024059740A1 (en) * | 2022-09-14 | 2024-03-21 | Synthego Corporation | Genetically modified polynucleotides and cells expressing modified mhc proteins and uses thereof |
| WO2024159071A1 (en) | 2023-01-27 | 2024-08-02 | Regeneron Pharmaceuticals, Inc. | Modified rhabdovirus glycoproteins and uses thereof |
| US20240287186A1 (en) | 2023-02-28 | 2024-08-29 | Regeneron Pharmaceuticals, Inc. | T cell activators and methods of use thereof |
| WO2025081106A2 (en) * | 2023-10-12 | 2025-04-17 | Vanderbilt University | Nanobody vaccine compositions |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4235871A (en) | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
| US4501728A (en) | 1983-01-06 | 1985-02-26 | Technology Unlimited, Inc. | Masking of liposomes from RES recognition |
| US4837028A (en) | 1986-12-24 | 1989-06-06 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| US5585362A (en) | 1989-08-22 | 1996-12-17 | The Regents Of The University Of Michigan | Adenovirus vectors for gene therapy |
| ATE237694T1 (de) | 1991-08-20 | 2003-05-15 | Us Gov Health & Human Serv | Adenovirus vermittelter gentransfer in den gastrointestinaltrakt |
| US5252479A (en) | 1991-11-08 | 1993-10-12 | Research Corporation Technologies, Inc. | Safe vector for gene therapy |
| FR2688514A1 (fr) | 1992-03-16 | 1993-09-17 | Centre Nat Rech Scient | Adenovirus recombinants defectifs exprimant des cytokines et medicaments antitumoraux les contenant. |
| AU680459B2 (en) | 1992-12-03 | 1997-07-31 | Genzyme Corporation | Gene therapy for cystic fibrosis |
| DE69434486T2 (de) | 1993-06-24 | 2006-07-06 | Advec Inc. | Adenovirus vektoren für gentherapie |
| BR9407956A (pt) | 1993-10-25 | 1996-11-26 | Canji Inc | Composiçao farmacêutica vetor de express o de adenovirus recombinante e kit par reduzir a proliferaçao de células tumorais |
| US5869270A (en) * | 1996-01-31 | 1999-02-09 | Sunol Molecular Corporation | Single chain MHC complexes and uses thereof |
| US6211342B1 (en) * | 1996-07-18 | 2001-04-03 | Children's Hospital Medical Center | Multivalent MHC complex peptide fusion protein complex for stimulating specific T cell function |
| US20050003431A1 (en) * | 1996-08-16 | 2005-01-06 | Wucherpfennig Kai W. | Monovalent, multivalent, and multimeric MHC binding domain fusion proteins and conjugates, and uses therefor |
| US7078387B1 (en) | 1998-12-28 | 2006-07-18 | Arch Development Corp. | Efficient and stable in vivo gene transfer to cardiomyocytes using recombinant adeno-associated virus vectors |
| US6287860B1 (en) | 2000-01-20 | 2001-09-11 | Isis Pharmaceuticals, Inc. | Antisense inhibition of MEKK2 expression |
| WO2002072631A2 (en) * | 2001-03-14 | 2002-09-19 | Dakocytomation Denmark A/S | Mhc molecule constructs and their usesfor diagnosis and therapy |
| DE102004014983A1 (de) * | 2004-03-26 | 2005-10-20 | Univ Stuttgart | Rekombinante Polypeptide der Mitglieder der TNF Ligandenfamilie und deren Verwendung |
| US7670595B2 (en) * | 2004-06-28 | 2010-03-02 | Merck Patent Gmbh | Fc-interferon-beta fusion proteins |
| US7855279B2 (en) | 2005-09-27 | 2010-12-21 | Amunix Operating, Inc. | Unstructured recombinant polymers and uses thereof |
| AU2007223888A1 (en) | 2006-03-06 | 2007-09-13 | Amunix, Inc. | Genetic packages and uses thereof |
| US8518697B2 (en) * | 2006-04-04 | 2013-08-27 | Washington University | Single chain trimers and uses therefor |
| EP2155782A2 (en) * | 2007-03-26 | 2010-02-24 | Dako Denmark A/S | Mhc peptide complexes and uses thereof in infectious diseases |
| EP2185701A4 (en) | 2007-08-15 | 2011-03-02 | Amunix Operating Inc | COMPOSITIONS AND METHODS FOR ENHANCING THE PRODUCTION OF RECOMBINANT POLYPEPTIDES |
| EP2337795A2 (en) * | 2008-10-01 | 2011-06-29 | Dako Denmark A/S | Mhc multimers in cancer vaccines and immune monitoring |
| DK3178835T3 (da) * | 2009-02-03 | 2019-06-24 | Amunix Pharmaceuticals Inc | Forlængede rekombinante polypeptider og sammensætninger omfattende samme |
| US8956619B2 (en) * | 2011-10-25 | 2015-02-17 | University Of Maryland, Baltimore County | Soluble CD80 as a therapeutic to reverse immune supression in cancer patients |
| BR112015011111A2 (pt) * | 2012-11-30 | 2017-11-14 | Roche Glycart Ag | proteína multifuncional e formulação farmacêutica |
| CN111315768A (zh) * | 2017-09-07 | 2020-06-19 | 库尔生物制药有限公司 | 具有缀合位点的t细胞调节性多聚体多肽及其使用方法 |
| CN111886241A (zh) * | 2018-01-09 | 2020-11-03 | 库尔生物制药有限公司 | 多聚体t细胞调节多肽及其使用方法 |
-
2015
- 2015-06-15 SG SG10202006338UA patent/SG10202006338UA/en unknown
- 2015-06-15 CN CN201580027510.0A patent/CN106456733B/zh active Active
- 2015-06-15 JP JP2016565693A patent/JP6652932B2/ja active Active
- 2015-06-15 KR KR1020167034341A patent/KR102252119B1/ko active Active
- 2015-06-15 ES ES15809277T patent/ES2767259T3/es active Active
- 2015-06-15 PT PT158092775T patent/PT3157552T/pt unknown
- 2015-06-15 DK DK18212801.7T patent/DK3480213T3/da active
- 2015-06-15 WO PCT/US2015/035777 patent/WO2015195531A2/en not_active Ceased
- 2015-06-15 CN CN202110210453.7A patent/CN113248623A/zh active Pending
- 2015-06-15 HU HUE15809277A patent/HUE047255T2/hu unknown
- 2015-06-15 EP EP15809277.5A patent/EP3157552B1/en active Active
- 2015-06-15 PL PL15809277T patent/PL3157552T3/pl unknown
- 2015-06-15 US US15/306,678 patent/US20170058015A1/en not_active Abandoned
- 2015-06-15 ES ES18212801T patent/ES2770330T3/es active Active
- 2015-06-15 EP EP18212801.7A patent/EP3480213B1/en active Active
- 2015-06-15 CN CN202110210461.1A patent/CN113248624B/zh active Active
- 2015-06-15 SG SG11201609876TA patent/SG11201609876TA/en unknown
- 2015-06-15 AU AU2015277460A patent/AU2015277460B2/en active Active
- 2015-06-15 PT PT182128017T patent/PT3480213T/pt unknown
- 2015-06-15 EP EP18212805.8A patent/EP3483179B1/en active Active
- 2015-06-15 DK DK15809277.5T patent/DK3157552T3/da active
- 2015-06-15 HU HUE18212801A patent/HUE048076T2/hu unknown
- 2015-06-15 PL PL18212801T patent/PL3480213T3/pl unknown
- 2015-06-17 TW TW104119612A patent/TWI696633B/zh active
- 2015-06-17 TW TW110108178A patent/TWI795740B/zh active
- 2015-06-17 TW TW108133859A patent/TWI722576B/zh active
-
2016
- 2016-11-15 IL IL248979A patent/IL248979B/en active IP Right Grant
-
2018
- 2018-06-06 US US16/001,153 patent/US20180282392A1/en not_active Abandoned
-
2019
- 2019-05-12 IL IL266570A patent/IL266570B/en active IP Right Grant
- 2019-05-16 AU AU2019203442A patent/AU2019203442B2/en active Active
- 2019-10-23 JP JP2019192453A patent/JP6652680B2/ja active Active
-
2020
- 2020-01-13 US US16/740,752 patent/US20200377569A1/en not_active Abandoned
- 2020-01-24 JP JP2020009921A patent/JP6995151B2/ja active Active
- 2020-06-11 IL IL275307A patent/IL275307B/en unknown
- 2020-08-25 US US17/001,847 patent/US20210238254A1/en not_active Abandoned
- 2020-09-09 US US17/015,282 patent/US20210047384A1/en active Pending
-
2021
- 2021-07-01 AU AU2021204594A patent/AU2021204594B2/en active Active
- 2021-12-14 JP JP2021202405A patent/JP7331075B2/ja active Active
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK3157552T3 (da) | Syntac-polypeptider og anvendelser deraf | |
| DK3412302T3 (da) | Modificerede fgf-21-polypeptider og anvendelser deraf | |
| DK3268470T3 (da) | Transposasepolypeptider og anvendelser deraf | |
| DK3448386T3 (da) | Isoquinolin-3-ylcarboxamider og fremstilling og anvendelse deraf | |
| DK3333191T3 (da) | Anti-C10ORF54-antistoffer og anvendelser deraf | |
| DK3303379T3 (da) | Tigit-bindende midler og anvendelser deraf | |
| DK3174906T3 (da) | Modificerede alginater til anti-fibrotiske materialer og anvendelser | |
| DK3126388T3 (da) | Anti-EGFRvIII-antistoffer og anvendelser deraf | |
| DK3189081T3 (da) | Cd123-bindende midler og anvendelser deraf | |
| DK3218358T3 (da) | Ifluorometyl-aminopyridiner og difluorometyl-aminopyrimidiner | |
| DK3212255T3 (da) | Selvorienterende sprøjte og sprøjtegrænseflade | |
| DK3302431T3 (da) | Taxanpartikler og anvendelse deraf | |
| IL246921B (en) | Binding proteins and methods of use thereof | |
| EP3205103C0 (en) | INTER AND INTRA UNIFICATION BLOCK COPY | |
| DK3210977T3 (da) | Hidtil ukendt aminoalkylbenzothiazepinderivat og anvendelse deraf | |
| DK3224603T3 (da) | Nordning og fremgangsmåde til materialekarakteristik | |
| DK4089113T3 (da) | Polypeptider | |
| DK3209773T3 (da) | Prolintolerante tripeptidylpeptidaser og anvendelser deraf | |
| DK3018183T3 (da) | Halogenolefinbaseret sammensætning og anvendelse deraf | |
| DK3161139T3 (da) | Tlr-4-specifikke aptamerer og anvendelser heraf | |
| DK3236991T3 (da) | Fgf21-derivater og anvendelser deraf | |
| DK3128005T3 (da) | Sirp-alfa-variantkonstruktioner og anvendelser deraf | |
| IL254591A0 (en) | Polypeptides | |
| DK3100050T3 (da) | Immobiliserede proteiner og anvendelse deraf | |
| DK3321279T3 (da) | Exenatidmodificeringsmiddel og anvendelse deraf |