DK3464637T3 - Detektering af hæmatologiske forstyrrelser ved hjælp af cellefrit DNA i blod - Google Patents
Detektering af hæmatologiske forstyrrelser ved hjælp af cellefrit DNA i blod Download PDFInfo
- Publication number
- DK3464637T3 DK3464637T3 DK17805833.5T DK17805833T DK3464637T3 DK 3464637 T3 DK3464637 T3 DK 3464637T3 DK 17805833 T DK17805833 T DK 17805833T DK 3464637 T3 DK3464637 T3 DK 3464637T3
- Authority
- DK
- Denmark
- Prior art keywords
- blood
- cell
- detection
- free dna
- haematological disorders
- Prior art date
Links
- 208000023661 Haematological disease Diseases 0.000 title 1
- 239000008280 blood Substances 0.000 title 1
- 210000004369 blood Anatomy 0.000 title 1
- 238000001514 detection method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/154—Methylation markers
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662343050P | 2016-05-30 | 2016-05-30 | |
| PCT/CN2017/086509 WO2017206888A1 (en) | 2016-05-30 | 2017-05-30 | Detecting hematological disorders using cell-free dna in blood |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3464637T3 true DK3464637T3 (da) | 2021-07-26 |
Family
ID=60479040
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK21163406.8T DK3885447T3 (da) | 2016-05-30 | 2017-05-30 | Påvisning af hæmatologiske lidelser ved hjælp af cellefrit DNA i blod |
| DK17805833.5T DK3464637T3 (da) | 2016-05-30 | 2017-05-30 | Detektering af hæmatologiske forstyrrelser ved hjælp af cellefrit DNA i blod |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK21163406.8T DK3885447T3 (da) | 2016-05-30 | 2017-05-30 | Påvisning af hæmatologiske lidelser ved hjælp af cellefrit DNA i blod |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US10781490B2 (da) |
| EP (3) | EP3885447B1 (da) |
| JP (3) | JP6987393B2 (da) |
| KR (3) | KR102482616B1 (da) |
| CN (2) | CN109196120B (da) |
| AU (2) | AU2017274038B2 (da) |
| CA (1) | CA3025708A1 (da) |
| DK (2) | DK3885447T3 (da) |
| IL (2) | IL262953B2 (da) |
| SG (1) | SG11201810544WA (da) |
| WO (1) | WO2017206888A1 (da) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3889272A1 (en) | 2014-07-18 | 2021-10-06 | The Chinese University of Hong Kong | Methylation pattern analysis of tissues in dna mixture |
| CA3025708A1 (en) | 2016-05-30 | 2017-12-07 | The Chinese University Of Hong Kong | Detecting hematological disorders using cell-free dna in blood |
| EP3548632A4 (en) | 2016-11-30 | 2020-06-24 | The Chinese University Of Hong Kong | ANALYSIS OF CELLULAR DNA IN URINE AND OTHER SAMPLES |
| TW202348802A (zh) | 2017-01-25 | 2023-12-16 | 香港中文大學 | 使用核酸片段之診斷應用 |
| EP3658684B1 (en) | 2017-07-26 | 2023-08-30 | The Chinese University Of Hong Kong | Enhancement of cancer screening using cell-free viral nucleic acids |
| EP3947717A4 (en) | 2019-03-25 | 2022-12-28 | The Chinese University Of Hong Kong | DETERMINATION OF LINEAR AND ROUND SHAPES OF CIRCULATION NUCLEIC ACIDS |
| CN110361531B (zh) * | 2019-08-02 | 2023-04-11 | 天津医科大学总医院 | 一种检测微粒促凝活性的实验方法 |
| CN111518876B (zh) * | 2020-05-11 | 2023-01-13 | 润方（北京）生物医药研究院有限公司 | 一种牛血红蛋白制品中牛源基因组dna定量检测方法及其应用 |
| KR102517894B1 (ko) * | 2021-02-23 | 2023-04-04 | 연세대학교 산학협력단 | 당뇨발에 의한 하지 절단 수술의 치료 반응성을 예측하는 방법 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2253461T3 (es) | 2002-03-05 | 2006-06-01 | Epigenomics Ag | Procedimiento y dispositivo para la determinacion de la especificidad del tejido y del adn que flota libre en tejidos corporales. |
| US20090176655A1 (en) * | 2007-11-16 | 2009-07-09 | Oncomethylome Sciences Sa | Methylation detection |
| US20110028333A1 (en) * | 2009-05-01 | 2011-02-03 | Brown University | Diagnosing, prognosing, and early detection of cancers by dna methylation profiling |
| WO2011092592A2 (en) | 2010-01-26 | 2011-08-04 | Nipd Genetics Ltd | Methods and compositions for noninvasive prenatal diagnosis of fetal aneuploidies |
| US10047397B2 (en) | 2010-04-16 | 2018-08-14 | Chronix Biomedical | Breast cancer associated circulating nucleic acid biomarkers |
| TWI719339B (zh) | 2010-11-30 | 2021-02-21 | 香港中文大學 | 與癌症有關之基因或分子變異之檢測 |
| US20120190021A1 (en) | 2011-01-25 | 2012-07-26 | Aria Diagnostics, Inc. | Detection of genetic abnormalities |
| US20140178348A1 (en) | 2011-05-25 | 2014-06-26 | The Regents Of The University Of California | Methods using DNA methylation for identifying a cell or a mixture of cells for prognosis and diagnosis of diseases, and for cell remediation therapies |
| WO2013045432A1 (en) | 2011-09-26 | 2013-04-04 | Qiagen Gmbh | Rapid method for isolating extracellular nucleic acids |
| ES2729554T3 (es) | 2011-10-21 | 2019-11-04 | Chronix Biomedical | Biomarcadores de ácidos nucleicos en circulación asociados al cáncer colorrectal |
| EP3839065A1 (en) | 2012-09-20 | 2021-06-23 | The Chinese University Of Hong Kong | Non-invasive determination of methylome of tumor from plasma |
| US9732390B2 (en) * | 2012-09-20 | 2017-08-15 | The Chinese University Of Hong Kong | Non-invasive determination of methylome of fetus or tumor from plasma |
| EP3099822A4 (en) | 2014-01-30 | 2017-08-30 | The Regents of the University of California | Methylation haplotyping for non-invasive diagnosis (monod) |
| FI4026917T3 (fi) | 2014-04-14 | 2024-02-14 | Yissum Research And Development Company Of The Hebrew Univ Of Jerusalem Ltd | Menetelmä ja välineistö solujen tai kudoksen kuoleman tai DNA:n kudos- tai solualkuperäin määrittämiseksi DNA-metylaatioanalyysin avulla |
| JP6681841B2 (ja) | 2014-05-09 | 2020-04-15 | ライフコーデックス アーゲー | 特別な細胞タイプに由来するｄｎａの検出とそれに関連する方法 |
| EP3889272A1 (en) | 2014-07-18 | 2021-10-06 | The Chinese University of Hong Kong | Methylation pattern analysis of tissues in dna mixture |
| US10364467B2 (en) | 2015-01-13 | 2019-07-30 | The Chinese University Of Hong Kong | Using size and number aberrations in plasma DNA for detecting cancer |
| CA3025708A1 (en) | 2016-05-30 | 2017-12-07 | The Chinese University Of Hong Kong | Detecting hematological disorders using cell-free dna in blood |
-
2017
- 2017-05-30 CA CA3025708A patent/CA3025708A1/en active Pending
- 2017-05-30 CN CN201780033380.0A patent/CN109196120B/zh active Active
- 2017-05-30 IL IL262953A patent/IL262953B2/en unknown
- 2017-05-30 DK DK21163406.8T patent/DK3885447T3/da active
- 2017-05-30 KR KR1020187037241A patent/KR102482616B1/ko active IP Right Grant
- 2017-05-30 AU AU2017274038A patent/AU2017274038B2/en active Active
- 2017-05-30 IL IL303115A patent/IL303115A/en unknown
- 2017-05-30 DK DK17805833.5T patent/DK3464637T3/da active
- 2017-05-30 CN CN202210823171.9A patent/CN115161390A/zh active Pending
- 2017-05-30 EP EP21163406.8A patent/EP3885447B1/en active Active
- 2017-05-30 US US15/608,863 patent/US10781490B2/en active Active
- 2017-05-30 EP EP17805833.5A patent/EP3464637B1/en active Active
- 2017-05-30 KR KR1020227044979A patent/KR102605504B1/ko active IP Right Grant
- 2017-05-30 KR KR1020237039843A patent/KR20230164209A/ko active Application Filing
- 2017-05-30 SG SG11201810544WA patent/SG11201810544WA/en unknown
- 2017-05-30 EP EP23214529.2A patent/EP4324937A3/en active Pending
- 2017-05-30 JP JP2018562945A patent/JP6987393B2/ja active Active
- 2017-05-30 WO PCT/CN2017/086509 patent/WO2017206888A1/en unknown
-
2020
- 2020-08-19 US US16/997,435 patent/US11873527B2/en active Active
-
2021
- 2021-11-24 JP JP2021189986A patent/JP2022024127A/ja active Pending
-
2023
- 2023-05-26 AU AU2023203305A patent/AU2023203305A1/en active Pending
-
2024
- 2024-02-13 JP JP2024019464A patent/JP2024054311A/ja active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK3464637T3 (da) | Detektering af hæmatologiske forstyrrelser ved hjælp af cellefrit DNA i blod | |
| DK3250703T3 (da) | Ligeringsanalyser i væskefase | |
| DK3055803T3 (da) | Sporing og analyse af kliniske resultater | |
| DK3408407T3 (da) | Fremgangsmåder til påvisning af cpg-methylering af tumorafledt dna i blodprøver | |
| DK3643795T3 (da) | Fremganffremgangsmåde til bestemmelse af celle- eller vævsdød ved analyse af dna-methylering | |
| DK3954288T3 (da) | Medicinsk anordning til påvisning af mindst én analyt i en kropsvæske | |
| DK3351645T3 (da) | Pyrofosforolytisk sekventering ved anvendelse af nanoporer | |
| BR112017002232A2 (pt) | combinações de inibidor de tirosina quinase de bruton e usos das mesmas | |
| DK3082831T3 (da) | Sammensætning på basis af methyl-cyclodextriner til behandling og/eller forebyggelse af sygdomme ved forøgelse af koncentrationen af hdl-kolesterol | |
| DK3138489T3 (da) | Sæt til bestemmelse af en analytkoncentration | |
| DK3191489T3 (da) | Pyrrolopyrimidiner til anvendelse ved influenzavirusinfektion | |
| DK3519558T3 (da) | Anvendelse af modificeret nyrevæv i assays | |
| DK3481846T3 (da) | 11-substituerede 24-hydroxysteroler til anvendelse til behandling af nmda-relaterede tilstande | |
| BR112016020889A2 (pt) | variantes de hppd e métodos de uso | |
| DK3508209T3 (da) | Sammensætninger med et svækket newcastle sygdoms-virus og fremgangsmåder til anvendelse til behandling af neoplasi | |
| DK3302519T3 (da) | Ornithodoros-moubata-komplement-inhibitor til anvendelse i behandlingen af akut graft-versus-host-sygdom | |
| DK3909506T3 (da) | Medicinsk anordning til påvisning af mindst én analyt i en kropsvæske | |
| DK3169232T3 (da) | Intermitterende måling af partialtrykket af en analyt i hudvæv | |
| DK3391902T3 (da) | Plasminogen til anvendelse i behandlingen af diabetisk angiokardiopati | |
| DK3556383T3 (da) | Plasminogen til anvendelse ved behandling af diabetes | |
| BR112016004236A2 (pt) | Método para determinar a presença ou ausência de um medicamento de abuso ou metabólito em amostras de cabelo | |
| DK3271864T3 (da) | Vævsprøveanalyseteknik | |
| DK3419435T3 (da) | Frysekoncentration af rod- eller knoldsaft | |
| DK3174631T3 (da) | Adsorptionsmiddel på basis af natriumholdigt aluminiumoxid doteret med et alkalisk grundstof til indfangning af sure molekyler | |
| DK3093022T3 (da) | Gata-3-inhibitorer til anvendelse i behandlingen af th2-drevet astma |