DK3450545T5 - Pluripotente stamceller opnået ved ikke-viral omprogrammering - Google Patents
Pluripotente stamceller opnået ved ikke-viral omprogrammering Download PDFInfo
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- DK3450545T5 DK3450545T5 DK18200217.0T DK18200217T DK3450545T5 DK 3450545 T5 DK3450545 T5 DK 3450545T5 DK 18200217 T DK18200217 T DK 18200217T DK 3450545 T5 DK3450545 T5 DK 3450545T5
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- stem cells
- pluripotent stem
- cells obtained
- viral reprogramming
- reprogramming
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- 210000001778 pluripotent stem cell Anatomy 0.000 title 1
- 230000008672 reprogramming Effects 0.000 title 1
- 230000003612 virological effect Effects 0.000 title 1
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/602—Sox-2
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/603—Oct-3/4
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/604—Klf-4
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/605—Nanog
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/606—Transcription factors c-Myc
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/608—Lin28
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2510/00—Genetically modified cells
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
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- Biochemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Developmental Biology & Embryology (AREA)
- Transplantation (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10836208P | 2008-10-24 | 2008-10-24 | |
| EP09744285.9A EP2356221B1 (en) | 2008-10-24 | 2009-10-23 | Pluripotent stem cells obtained by non-viral reprogramming |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK3450545T3 DK3450545T3 (da) | 2023-10-02 |
| DK3450545T5 true DK3450545T5 (da) | 2024-09-09 |
Family
ID=41698343
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK18200217.0T DK3450545T5 (da) | 2008-10-24 | 2009-10-23 | Pluripotente stamceller opnået ved ikke-viral omprogrammering |
| DK09744285.9T DK2356221T3 (en) | 2008-10-24 | 2009-10-23 | Pluripotent stem cells obtained by non-viral reprogramming |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK09744285.9T DK2356221T3 (en) | 2008-10-24 | 2009-10-23 | Pluripotent stem cells obtained by non-viral reprogramming |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US8268620B2 (cg-RX-API-DMAC10.html) |
| EP (2) | EP3450545B1 (cg-RX-API-DMAC10.html) |
| JP (5) | JP2012506702A (cg-RX-API-DMAC10.html) |
| CN (2) | CN102239249A (cg-RX-API-DMAC10.html) |
| CA (1) | CA2741090C (cg-RX-API-DMAC10.html) |
| DK (2) | DK3450545T5 (cg-RX-API-DMAC10.html) |
| ES (1) | ES2959327T3 (cg-RX-API-DMAC10.html) |
| IL (1) | IL212433B (cg-RX-API-DMAC10.html) |
| SG (1) | SG10201600234PA (cg-RX-API-DMAC10.html) |
| WO (1) | WO2010048567A1 (cg-RX-API-DMAC10.html) |
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| US8278104B2 (en) | 2005-12-13 | 2012-10-02 | Kyoto University | Induced pluripotent stem cells produced with Oct3/4, Klf4 and Sox2 |
| EP2206724A1 (en) | 2005-12-13 | 2010-07-14 | Kyoto University | Nuclear reprogramming factor |
| DK3399025T3 (da) | 2007-03-23 | 2025-06-16 | Wisconsin Alumni Res Found | Omprogrammering af somatiske celler |
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| WO2026117659A1 (en) | 2024-11-27 | 2026-06-04 | Bluerock Therapeutics Lp | Methods of treating inherited retinal diseases |
| US20260226420A1 (en) | 2025-01-31 | 2026-08-06 | FUJIFILM Holdings America Corporation | Methods for the production of hepatic stellate cells from human pluripotent stem cells |
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| US8278104B2 (en) * | 2005-12-13 | 2012-10-02 | Kyoto University | Induced pluripotent stem cells produced with Oct3/4, Klf4 and Sox2 |
| DK3399025T3 (da) * | 2007-03-23 | 2025-06-16 | Wisconsin Alumni Res Found | Omprogrammering af somatiske celler |
| JP2008307007A (ja) * | 2007-06-15 | 2008-12-25 | Bayer Schering Pharma Ag | 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞 |
| EP2072618A1 (en) | 2007-12-14 | 2009-06-24 | Johannes Gutenberg-Universität Mainz | Use of RNA for reprogramming somatic cells |
| CN101250502A (zh) * | 2008-04-01 | 2008-08-27 | 中国科学院上海生命科学研究院 | 一种诱导的多潜能干细胞的制备方法 |
| JP5346925B2 (ja) | 2008-05-02 | 2013-11-20 | 国立大学法人京都大学 | 核初期化方法 |
| ES2587395T3 (es) * | 2008-06-04 | 2016-10-24 | Cellular Dynamics International, Inc. | Procedimientos para la producción de células IPS usando un enfoque no vírico |
| JP2011525794A (ja) * | 2008-06-26 | 2011-09-29 | 国立大学法人大阪大学 | ｉＰＳ細胞の製造方法および製造キット |
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| EP3450545B1 (en) * | 2008-10-24 | 2023-08-23 | Wisconsin Alumni Research Foundation | Pluripotent stem cells obtained by non-viral reprogramming |
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| JP6861189B2 (ja) | 2021-04-21 |
| CA2741090A1 (en) | 2010-04-29 |
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| US20130217117A1 (en) | 2013-08-22 |
| CN102239249A (zh) | 2011-11-09 |
| JP6312638B2 (ja) | 2018-04-18 |
| US20190330654A1 (en) | 2019-10-31 |
| CN105802917A (zh) | 2016-07-27 |
| US20220010331A1 (en) | 2022-01-13 |
| EP3450545B1 (en) | 2023-08-23 |
| IL212433A0 (en) | 2011-06-30 |
| DK2356221T3 (en) | 2019-02-18 |
| JP2021094040A (ja) | 2021-06-24 |
| DK3450545T3 (da) | 2023-10-02 |
| JP2016220686A (ja) | 2016-12-28 |
| US20100184227A1 (en) | 2010-07-22 |
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