SG10201600234PA - Pluripotent Stem Cells Obtained By Non-Viral Reprogramming - Google Patents
Pluripotent Stem Cells Obtained By Non-Viral ReprogrammingInfo
- Publication number
- SG10201600234PA SG10201600234PA SG10201600234PA SG10201600234PA SG10201600234PA SG 10201600234P A SG10201600234P A SG 10201600234PA SG 10201600234P A SG10201600234P A SG 10201600234PA SG 10201600234P A SG10201600234P A SG 10201600234PA SG 10201600234P A SG10201600234P A SG 10201600234PA
- Authority
- SG
- Singapore
- Prior art keywords
- stem cells
- pluripotent stem
- cells obtained
- viral reprogramming
- reprogramming
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/602—Sox-2
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/603—Oct-3/4
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/604—Klf-4
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/605—Nanog
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/606—Transcription factors c-Myc
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/608—Lin28
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10836208P | 2008-10-24 | 2008-10-24 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG10201600234PA true SG10201600234PA (en) | 2016-02-26 |
Family
ID=41698343
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201600234PA SG10201600234PA (en) | 2008-10-24 | 2009-10-23 | Pluripotent Stem Cells Obtained By Non-Viral Reprogramming |
Country Status (10)
Country | Link |
---|---|
US (4) | US8268620B2 (en) |
EP (2) | EP2356221B1 (en) |
JP (5) | JP2012506702A (en) |
CN (2) | CN102239249A (en) |
CA (1) | CA2741090C (en) |
DK (2) | DK2356221T3 (en) |
ES (1) | ES2959327T3 (en) |
IL (1) | IL212433B (en) |
SG (1) | SG10201600234PA (en) |
WO (1) | WO2010048567A1 (en) |
Families Citing this family (77)
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EA018039B1 (en) * | 2005-12-13 | 2013-05-30 | Киото Юниверсити | Nuclear reprogramming factor |
US8129187B2 (en) | 2005-12-13 | 2012-03-06 | Kyoto University | Somatic cell reprogramming by retroviral vectors encoding Oct3/4. Klf4, c-Myc and Sox2 |
US20090227032A1 (en) * | 2005-12-13 | 2009-09-10 | Kyoto University | Nuclear reprogramming factor and induced pluripotent stem cells |
US8278104B2 (en) * | 2005-12-13 | 2012-10-02 | Kyoto University | Induced pluripotent stem cells produced with Oct3/4, Klf4 and Sox2 |
US8440461B2 (en) | 2007-03-23 | 2013-05-14 | Wisconsin Alumni Research Foundation | Reprogramming somatic cells using retroviral vectors comprising Oct-4 and Sox2 genes |
JP2008307007A (en) * | 2007-06-15 | 2008-12-25 | Bayer Schering Pharma Ag | Human pluripotent stem cell induced from human tissue-originated undifferentiated stem cell after birth |
US9213999B2 (en) * | 2007-06-15 | 2015-12-15 | Kyoto University | Providing iPSCs to a customer |
WO2009133971A1 (en) * | 2008-05-02 | 2009-11-05 | Kyoto University | Method of nuclear reprogramming |
ES2587395T3 (en) | 2008-06-04 | 2016-10-24 | Cellular Dynamics International, Inc. | Procedures for the production of IPS cells using a non-viral approach |
EP3330371A1 (en) * | 2008-08-12 | 2018-06-06 | Cellular Dynamics International, Inc. | Methods for the production of ips cells |
WO2010048567A1 (en) * | 2008-10-24 | 2010-04-29 | Wisconsin Alumni Research Foundation | Pluripotent stem cells obtained by non-viral reprogramming |
CN105925535A (en) | 2009-06-05 | 2016-09-07 | 细胞动力国际有限公司 | Method Of Reprogramming T Cells And Hematopoietic Cells |
US8048675B1 (en) * | 2010-05-12 | 2011-11-01 | Ipierian, Inc. | Integration-free human induced pluripotent stem cells from blood |
EP3382008A1 (en) | 2010-06-15 | 2018-10-03 | FUJIFILM Cellular Dynamics, Inc. | Generation of induced pluripotent stem cells from small volumes of peripheral blood |
BR112013002811A8 (en) * | 2010-08-05 | 2020-01-28 | Wisconsin Alumni Res Found | simplified basic means for human pluripotent cell culture |
US9279107B2 (en) | 2010-08-05 | 2016-03-08 | Wisconsin Alumni Research Foundation | Simplified basic media for human pluripotent cell culture |
EP2616554A1 (en) | 2010-09-17 | 2013-07-24 | President and Fellows of Harvard College | Functional genomics assay for characterizing pluripotent stem cell utility and safety |
US9133266B2 (en) | 2011-05-06 | 2015-09-15 | Wisconsin Alumni Research Foundation | Vitronectin-derived cell culture substrate and uses thereof |
EP2732029B1 (en) * | 2011-07-11 | 2019-01-16 | FUJIFILM Cellular Dynamics, Inc. | Methods for cell reprogramming and genome engineering |
US10391126B2 (en) | 2011-11-18 | 2019-08-27 | Board Of Regents, The University Of Texas System | CAR+ T cells genetically modified to eliminate expression of T-cell receptor and/or HLA |
US8497124B2 (en) | 2011-12-05 | 2013-07-30 | Factor Bioscience Inc. | Methods and products for reprogramming cells to a less differentiated state |
EP2788033B1 (en) | 2011-12-05 | 2017-05-31 | Factor Bioscience Inc. | Methods and products for transfecting cells |
WO2013090919A1 (en) | 2011-12-16 | 2013-06-20 | Wisconsin Alumni Research Foundation | Fgf-2 having enhanced stability |
US20130266541A1 (en) * | 2012-04-06 | 2013-10-10 | The Johns Hopkins University | Human induced pluripotent stem cells |
CN104769112A (en) | 2012-11-01 | 2015-07-08 | 菲克特生物科学股份有限公司 | Methods and products for expressing proteins in cells |
EP3323884A1 (en) | 2013-02-01 | 2018-05-23 | The United States Of America as Represented by the Secretary, Department of Health an Human Service | Method for generating retinal pigment epithelium (rpe) cells from induced pluripotent stem cells (ipscs) |
EP3008229B1 (en) | 2013-06-10 | 2020-05-27 | President and Fellows of Harvard College | Early developmental genomic assay for characterizing pluripotent stem cell utility and safety |
WO2015006725A2 (en) | 2013-07-12 | 2015-01-15 | Cedars-Sinai Medical Center | Generation of induced pluripotent stem cells from normal human mammary epithelial cells |
KR101551926B1 (en) | 2013-09-06 | 2015-09-10 | 가톨릭대학교 산학협력단 | Human induced pluripotent stem cells and method for producing animal expressed human immune system using the same |
US11377639B2 (en) | 2013-11-15 | 2022-07-05 | Wisconsin Alumni Research Foundation | Lineage reprogramming to induced cardiac progenitor cells (iCPC) by defined factors |
MX2016009771A (en) | 2014-01-31 | 2016-11-14 | Factor Bioscience Inc | Methods and products for nucleic acid production and delivery. |
US20170044500A1 (en) | 2014-04-24 | 2017-02-16 | Board Of Regents, The University Of Texas System | Application of induced pluripotent stem cells to generate adoptive cell therapy products |
EP3215168B1 (en) * | 2014-10-31 | 2023-08-02 | The Trustees of the University of Pennsylvania | Altering gene expression in modified t cells and uses thereof |
WO2016131052A1 (en) | 2015-02-13 | 2016-08-18 | Factor Bioscience Inc. | Nucleic acid products and methods of administration thereof |
JP6873898B2 (en) * | 2015-04-14 | 2021-05-19 | 国立大学法人京都大学 | A method for producing a stem cell clone suitable for inducing differentiation into somatic cells |
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US20190169569A1 (en) | 2015-09-08 | 2019-06-06 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Serv | Method for reproducible differentiation of clinical-grade retinal pigment epithelium cells |
ES2903442T3 (en) | 2015-09-08 | 2022-04-01 | Fujifilm Cellular Dynamics Inc | MACS-based purification of stem cell-derived retinal pigment epithelium |
CN105219729B (en) * | 2015-09-28 | 2018-09-25 | 首都医科大学宣武医院 | A kind of method and application thereof using nonconformity plasmid vector induced nerve stem cells |
WO2017070337A1 (en) | 2015-10-20 | 2017-04-27 | Cellular Dynamics International, Inc. | Methods for directed differentiation of pluripotent stem cells to immune cells |
WO2017196175A1 (en) | 2016-05-12 | 2017-11-16 | Erasmus University Medical Center Rotterdam | A method for culturing myogenic cells, cultures obtained therefrom, screening methods, and cell culture medium. |
CN105861447B (en) * | 2016-06-13 | 2017-12-19 | 广州市搏克生物技术有限公司 | A kind of non-viral iPSCs inducing compositions and its kit |
US11572545B2 (en) | 2016-06-16 | 2023-02-07 | Cedars-Sinai Medical Center | Efficient method for reprogramming blood to induced pluripotent stem cells |
US10221395B2 (en) | 2016-06-16 | 2019-03-05 | Cedars-Sinai Medical Center | Efficient method for reprogramming blood to induced pluripotent stem cells |
CA3029582A1 (en) | 2016-07-01 | 2018-01-04 | Research Development Foundation | Elimination of proliferating cells from stem cell-derived grafts |
WO2018026723A1 (en) | 2016-08-01 | 2018-02-08 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Human induced pluripotent stem cells for high efficiency genetic engineering |
WO2018035377A1 (en) | 2016-08-17 | 2018-02-22 | Factor Bioscience Inc. | Nucleic acid products and methods of administration thereof |
CN110050061A (en) | 2016-10-05 | 2019-07-23 | 富士胶片细胞动力公司 | The mature pedigree of generation is induced multi-potent stem cell from what is destroyed with MeCP2 |
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US11530388B2 (en) | 2017-02-14 | 2022-12-20 | University of Pittsburgh—of the Commonwealth System of Higher Education | Methods of engineering human induced pluripotent stem cells to produce liver tissue |
MX2019011897A (en) | 2017-04-18 | 2019-11-28 | Fujifilm Cellular Dynamics Inc | Antigen-specific immune effector cells. |
US11572544B2 (en) | 2017-06-14 | 2023-02-07 | The Children's Medical Center Corporation | Hematopoietic stem and progenitor cells derived from hemogenic endothelial cells by episomal plasmid gene transfer |
US10760057B2 (en) | 2017-07-06 | 2020-09-01 | Wisconsin Alumni Research Foundation | Human pluripotent stem cell-based screening for smooth muscle cell differentiation and disease |
NL2019517B1 (en) | 2017-09-08 | 2019-03-19 | Univ Erasmus Med Ct Rotterdam | New therapy for Pompe disease |
US20190100730A1 (en) | 2017-10-03 | 2019-04-04 | Wallkill BioPharma, Inc. | Treating diabetes with genetically modified beta cells |
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AU2019336221A1 (en) | 2018-09-07 | 2021-03-04 | Wisconsin Alumni Research Foundation | Generation of hematopoietic progenitor cells from human pluripotent stem cells |
JP2022513073A (en) | 2018-11-19 | 2022-02-07 | ザ ユナイテッド ステイツ オブ アメリカ アズ リプリゼンテッド バイ ザ セクレタリー、デパートメント オブ ヘルス アンド ヒューマン サービシーズ | Biodegradable tissue replacement implants and their use |
CA3121027A1 (en) | 2018-11-28 | 2020-06-04 | Board Of Regents, The University Of Texas System | Multiplex genome editing of immune cells to enhance functionality and resistance to suppressive environment |
EP3886874A1 (en) | 2018-11-29 | 2021-10-06 | Board of Regents, The University of Texas System | Methods for ex vivo expansion of natural killer cells and use thereof |
US10501404B1 (en) | 2019-07-30 | 2019-12-10 | Factor Bioscience Inc. | Cationic lipids and transfection methods |
EP4118234A1 (en) | 2020-03-09 | 2023-01-18 | FUJIFILM Corporation | Markers specific for pluripotent stem cells, and methods of using the same |
IL298085A (en) | 2020-05-29 | 2023-01-01 | Fujifilm Cellular Dynamics Inc | Retinal pigmented epithelium and photoreceptor dual cell aggregates and methods of use thereof |
US20230212509A1 (en) | 2020-05-29 | 2023-07-06 | FUJIFILM Cellular Dynamics, Inc. | Bilayer of retinal pigmented epithelium and photoreceptors and use thereof |
EP3922431A1 (en) | 2020-06-08 | 2021-12-15 | Erasmus University Medical Center Rotterdam | Method of manufacturing microdevices for lab-on-chip applications |
CA3201499A1 (en) | 2020-11-13 | 2022-05-19 | Catamaran Bio, Inc. | Genetically modified natural killer cells and methods of use thereof |
WO2022115611A1 (en) | 2020-11-25 | 2022-06-02 | Catamaran Bio, Inc. | Cellular therapeutics engineered with signal modulators and methods of use thereof |
BR112023018844A2 (en) | 2021-04-07 | 2023-10-10 | Century Therapeutics Inc | COMPOSITIONS AND METHODS FOR GENERATION OF GAMMA-DELTA T CELLS FROM INDUCED PLURIPOTENT STEM CELLS |
CA3214473A1 (en) | 2021-04-07 | 2022-10-13 | Century Therapeutics, Inc. | Compositions and methods for generating alpha-beta t cells from induced pluripotent stem cells |
EP4347796A1 (en) | 2021-05-26 | 2024-04-10 | Fujifilm Cellular Dynamics, Inc. | Methods to prevent rapid silencing of genes in pluripotent stem cells |
CA3220433A1 (en) | 2021-05-28 | 2022-12-01 | Arvydas Maminishkis | Biodegradable tissue scaffold with secondary matrix to host weakly adherent cells |
EP4347795A1 (en) | 2021-05-28 | 2024-04-10 | The United States of America, as represented by The Secretary, Department of Health and Human Services | Methods to generate macular, central and peripheral retinal pigment epithelial cells |
CA3231501A1 (en) | 2021-09-13 | 2023-03-16 | Steven Kattman | Methods for the production of committed cardiac progenitor cells |
WO2023172514A1 (en) | 2022-03-07 | 2023-09-14 | Catamaran Bio, Inc. | Engineered immune cell therapeutics targeted to her2 and methods of use thereof |
WO2023240147A1 (en) | 2022-06-08 | 2023-12-14 | Century Therapeutics, Inc. | Genetically engineered cells expressing cd16 variants and nkg2d and uses thereof |
US20240003871A1 (en) | 2022-06-29 | 2024-01-04 | FUJIFILM Cellular Dynamics, Inc. | Ipsc-derived astrocytes and methods of use thereof |
WO2024073776A1 (en) | 2022-09-30 | 2024-04-04 | FUJIFILM Cellular Dynamics, Inc. | Methods for the production of cardiac fibroblasts |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9223084D0 (en) | 1992-11-04 | 1992-12-16 | Imp Cancer Res Tech | Compounds to target cells |
US5925333A (en) * | 1995-11-15 | 1999-07-20 | Massachusetts Institute Of Technology | Methods for modulation of lipid uptake |
IL147990A0 (en) * | 1999-08-05 | 2002-09-12 | Mcl Llc | Multipotent adult stem cells and methods for isolation |
AU2004211654B2 (en) | 2003-02-07 | 2009-03-05 | Wisconsin Alumni Research Foundation | Directed genetic modifications of human stem cells |
US8278104B2 (en) * | 2005-12-13 | 2012-10-02 | Kyoto University | Induced pluripotent stem cells produced with Oct3/4, Klf4 and Sox2 |
US8440461B2 (en) * | 2007-03-23 | 2013-05-14 | Wisconsin Alumni Research Foundation | Reprogramming somatic cells using retroviral vectors comprising Oct-4 and Sox2 genes |
JP2008307007A (en) * | 2007-06-15 | 2008-12-25 | Bayer Schering Pharma Ag | Human pluripotent stem cell induced from human tissue-originated undifferentiated stem cell after birth |
EP2072618A1 (en) | 2007-12-14 | 2009-06-24 | Johannes Gutenberg-Universität Mainz | Use of RNA for reprogramming somatic cells |
CN101250502A (en) * | 2008-04-01 | 2008-08-27 | 中国科学院上海生命科学研究院 | Method for preparing evoked pluripotent stem cell |
WO2009133971A1 (en) | 2008-05-02 | 2009-11-05 | Kyoto University | Method of nuclear reprogramming |
ES2587395T3 (en) * | 2008-06-04 | 2016-10-24 | Cellular Dynamics International, Inc. | Procedures for the production of IPS cells using a non-viral approach |
WO2009157201A1 (en) * | 2008-06-26 | 2009-12-30 | Osaka University | Method and kit for preparing ips cells |
WO2010012077A1 (en) * | 2008-07-28 | 2010-02-04 | Mount Sinai Hospital | Compositions, methods and kits for reprogramming somatic cells |
WO2010048567A1 (en) * | 2008-10-24 | 2010-04-29 | Wisconsin Alumni Research Foundation | Pluripotent stem cells obtained by non-viral reprogramming |
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2009
- 2009-10-23 WO PCT/US2009/061935 patent/WO2010048567A1/en active Application Filing
- 2009-10-23 CA CA2741090A patent/CA2741090C/en active Active
- 2009-10-23 ES ES18200217T patent/ES2959327T3/en active Active
- 2009-10-23 US US12/605,220 patent/US8268620B2/en active Active
- 2009-10-23 DK DK09744285.9T patent/DK2356221T3/en active
- 2009-10-23 SG SG10201600234PA patent/SG10201600234PA/en unknown
- 2009-10-23 EP EP09744285.9A patent/EP2356221B1/en active Active
- 2009-10-23 CN CN2009801480130A patent/CN102239249A/en active Pending
- 2009-10-23 EP EP18200217.0A patent/EP3450545B1/en active Active
- 2009-10-23 JP JP2011533384A patent/JP2012506702A/en not_active Withdrawn
- 2009-10-23 DK DK18200217.0T patent/DK3450545T3/en active
- 2009-10-23 CN CN201610213440.4A patent/CN105802917A/en active Pending
-
2011
- 2011-04-17 IL IL212433A patent/IL212433B/en active IP Right Grant
-
2012
- 2012-09-07 US US13/607,072 patent/US20130217117A1/en not_active Abandoned
-
2015
- 2015-08-24 JP JP2015165051A patent/JP6312638B2/en active Active
-
2016
- 2016-08-26 JP JP2016165793A patent/JP2016220686A/en active Pending
-
2018
- 2018-08-23 JP JP2018155983A patent/JP6861189B2/en active Active
- 2018-12-04 US US16/209,722 patent/US20190330654A1/en not_active Abandoned
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2021
- 2021-03-29 JP JP2021055183A patent/JP7165228B2/en active Active
- 2021-06-21 US US17/352,873 patent/US20220010331A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
ES2959327T3 (en) | 2024-02-23 |
JP2018174945A (en) | 2018-11-15 |
CA2741090A1 (en) | 2010-04-29 |
WO2010048567A1 (en) | 2010-04-29 |
JP6861189B2 (en) | 2021-04-21 |
DK3450545T3 (en) | 2023-10-02 |
EP2356221B1 (en) | 2018-11-21 |
US20130217117A1 (en) | 2013-08-22 |
EP3450545B1 (en) | 2023-08-23 |
DK2356221T3 (en) | 2019-02-18 |
JP7165228B2 (en) | 2022-11-02 |
US8268620B2 (en) | 2012-09-18 |
US20190330654A1 (en) | 2019-10-31 |
IL212433B (en) | 2019-08-29 |
EP3450545A1 (en) | 2019-03-06 |
CA2741090C (en) | 2018-10-16 |
US20100184227A1 (en) | 2010-07-22 |
US20220010331A1 (en) | 2022-01-13 |
IL212433A0 (en) | 2011-06-30 |
JP6312638B2 (en) | 2018-04-18 |
JP2012506702A (en) | 2012-03-22 |
CN102239249A (en) | 2011-11-09 |
JP2015213522A (en) | 2015-12-03 |
EP2356221A1 (en) | 2011-08-17 |
CN105802917A (en) | 2016-07-27 |
JP2021094040A (en) | 2021-06-24 |
JP2016220686A (en) | 2016-12-28 |
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