DK3347061T3 - Injicerbare makroporøse hydrogeler - Google Patents

Injicerbare makroporøse hydrogeler Download PDF

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Publication number
DK3347061T3
DK3347061T3 DK16763035.9T DK16763035T DK3347061T3 DK 3347061 T3 DK3347061 T3 DK 3347061T3 DK 16763035 T DK16763035 T DK 16763035T DK 3347061 T3 DK3347061 T3 DK 3347061T3
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DK
Denmark
Prior art keywords
macroporous hydrogels
injectable
injectable macroporous
hydrogels
macroporous
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Application number
DK16763035.9T
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English (en)
Inventor
Nicolas Broguiere
Marcy Zenobi-Wong
Original Assignee
Eth Zuerich
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Publication of DK3347061T3 publication Critical patent/DK3347061T3/da

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/26—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
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    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • C08G65/331—Polymers modified by chemical after-treatment with organic compounds containing oxygen
    • C08G65/332—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides, or esters thereof
    • C08G65/3322—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides, or esters thereof acyclic
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/02—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
    • C08J3/03—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
    • C08J3/075—Macromolecular gels
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
    • C08J9/28—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof by elimination of a liquid phase from a macromolecular composition or article, e.g. drying of coagulum
    • C08J9/286—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof by elimination of a liquid phase from a macromolecular composition or article, e.g. drying of coagulum the liquid phase being a solvent for the monomers but not for the resulting macromolecular composition, i.e. macroporous or macroreticular polymers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
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    • C08L5/02—Dextran; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L53/00—Compositions of block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
    • C08L71/02—Polyalkylene oxides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
    • C08L71/08—Polyethers derived from hydroxy compounds or from their metallic derivatives
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L79/00—Compositions of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing nitrogen with or without oxygen or carbon only, not provided for in groups C08L61/00 - C08L77/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/06—Flowable or injectable implant compositions
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2371/00—Characterised by the use of polyethers obtained by reactions forming an ether link in the main chain; Derivatives of such polymers
    • C08J2371/02—Polyalkylene oxides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2405/00—Characterised by the use of polysaccharides or of their derivatives not provided for in groups C08J2401/00 or C08J2403/00
    • C08J2405/02—Dextran; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2405/00—Characterised by the use of polysaccharides or of their derivatives not provided for in groups C08J2401/00 or C08J2403/00
    • C08J2405/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2201/00—Properties
    • C08L2201/54—Aqueous solutions or dispersions

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  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Materials Engineering (AREA)
  • Zoology (AREA)
  • Botany (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK16763035.9T 2015-09-09 2016-09-08 Injicerbare makroporøse hydrogeler DK3347061T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15184552 2015-09-09
PCT/EP2016/071238 WO2017042301A1 (en) 2015-09-09 2016-09-08 Injectable macroporous hydrogels

Publications (1)

Publication Number Publication Date
DK3347061T3 true DK3347061T3 (da) 2021-08-23

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DK21168993.0T DK3868416T3 (da) 2015-09-09 2016-09-08 Injicerbare makroporøse hydrogeler
DK16763035.9T DK3347061T3 (da) 2015-09-09 2016-09-08 Injicerbare makroporøse hydrogeler

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Country Status (18)

Country Link
US (1) US20180264176A1 (da)
EP (2) EP3347061B1 (da)
JP (1) JP6829898B2 (da)
CN (2) CN113372579B (da)
AU (1) AU2016320395B2 (da)
CA (1) CA2992692C (da)
CY (1) CY1124571T1 (da)
DK (2) DK3868416T3 (da)
ES (1) ES2883235T3 (da)
HR (1) HRP20211306T1 (da)
HU (1) HUE055937T2 (da)
IL (1) IL257024B (da)
LT (1) LT3347061T (da)
PL (1) PL3347061T3 (da)
PT (1) PT3347061T (da)
RS (1) RS62239B1 (da)
SI (1) SI3347061T1 (da)
WO (1) WO2017042301A1 (da)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012044753A2 (en) 2010-10-01 2012-04-05 Applied Medical Resources Corporation Portable laparoscopic trainer
WO2013059575A1 (en) 2011-10-21 2013-04-25 Applied Medical Resources Corporation Simulated tissue structure for surgical training
CA2859967A1 (en) 2011-12-20 2013-06-27 Applied Medical Resources Corporation Advanced surgical simulation
AU2013323744B2 (en) 2012-09-26 2017-08-17 Applied Medical Resources Corporation Surgical training model for laparoscopic procedures
US10679520B2 (en) 2012-09-27 2020-06-09 Applied Medical Resources Corporation Surgical training model for laparoscopic procedures
ES2719808T3 (es) 2012-09-27 2019-07-16 Applied Med Resources Modelo de entrenamiento quirúrgico para procedimientos laparoscópicos
EP3929895A3 (en) 2013-03-01 2022-01-12 Applied Medical Resources Corporation Advanced surgical simulation constructions and methods
KR102607634B1 (ko) 2013-06-18 2023-11-29 어플라이드 메디컬 리소시스 코포레이션 수술 절차들을 가르치고 실습하기 위한 담낭 모델
US10198966B2 (en) 2013-07-24 2019-02-05 Applied Medical Resources Corporation Advanced first entry model for surgical simulation
AU2014293036B2 (en) 2013-07-24 2017-12-21 Applied Medical Resources Corporation First entry model
WO2015148817A1 (en) 2014-03-26 2015-10-01 Applied Medical Resources Corporation Simulated dissectible tissue
JP6754359B2 (ja) 2014-11-13 2020-09-09 アプライド メディカル リソーシーズ コーポレイション 模擬組織モデルおよび方法
WO2016134269A1 (en) 2015-02-19 2016-08-25 Applied Medical Resources Corporation Simulated tissue structures and methods
WO2016183412A1 (en) 2015-05-14 2016-11-17 Applied Medical Resources Corporation Synthetic tissue structures for electrosurgical training and simulation
JP6820281B2 (ja) 2015-06-09 2021-01-27 アプライド メディカル リソーシーズ コーポレイション 子宮摘出術モデル
ES2824529T3 (es) 2015-07-16 2021-05-12 Applied Med Resources Tejido disecable simulado
US10490105B2 (en) 2015-07-22 2019-11-26 Applied Medical Resources Corporation Appendectomy model
KR102649261B1 (ko) 2015-10-02 2024-03-20 어플라이드 메디컬 리소시스 코포레이션 자궁 절제술 모델
KR20180083919A (ko) 2015-11-20 2018-07-23 어플라이드 메디컬 리소시스 코포레이션 시뮬레이션된 절개가능 조직
JP7094888B2 (ja) 2016-03-24 2022-07-04 武田薬品工業株式会社 アルギネートヒドロゲル組成物
JP6925579B2 (ja) * 2016-03-31 2021-08-25 日油株式会社 環状ベンジリデンアセタール構造を有する生分解性ヒドロゲル
WO2018005301A1 (en) 2016-06-27 2018-01-04 Applied Medical Resources Corporation Simulated abdominal wall
US12097306B2 (en) * 2016-12-13 2024-09-24 Takeda Pharmaceutical Company Limited Conformal coating of biological surfaces
EP3583589A1 (en) 2017-02-14 2019-12-25 Applied Medical Resources Corporation Laparoscopic training system
US10847057B2 (en) 2017-02-23 2020-11-24 Applied Medical Resources Corporation Synthetic tissue structures for electrosurgical training and simulation
WO2019048714A2 (en) * 2017-09-11 2019-03-14 Evorion Biotechnologies Gmbh SYSTEMS, METHODS AND HYDROGELS OF CELL CULTURE AND ANALYSIS
CN108893445A (zh) * 2018-07-26 2018-11-27 南方医科大学 一种引导视网膜神经节细胞及其轴突生长延展的方法
CN109316628B (zh) * 2018-09-21 2021-04-20 广州远想生物科技有限公司 一种凝胶及其制备方法和应用
CN109731133B (zh) * 2019-02-01 2020-09-01 浙江大学 一种抗菌、抗粘附、可注射式温敏壳聚糖凝胶敷料及其制备方法
US11680107B2 (en) * 2019-03-22 2023-06-20 Taipei Medical University Hydrogel composition for drug delivery and uses thereof
CN114222777B (zh) 2019-08-28 2024-05-14 波士顿科学国际有限公司 多臂聚恶唑啉和与其相关的组合物、系统和方法
EP4084802A4 (en) * 2020-01-03 2024-03-13 Repertoire Immune Medicines, Inc. COMPOSITIONS OF HYDROGELS AND METHODS OF USE THEREOF
CN112898600B (zh) * 2021-02-07 2023-05-23 西安工业大学 一种聚多巴胺可逆粘附凝胶的分相制备方法
WO2023135155A1 (en) 2022-01-12 2023-07-20 Eth Zurich Photocurable phase-separating hydrogels
WO2023242189A1 (en) 2022-06-13 2023-12-21 Eth Zurich Collagen visualization on microfluidic device

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0213937A (pt) * 2001-11-07 2004-10-26 Univ Zuerich Matriz sintética para encravamento celular controlado e regeneração de tecido
US20070264227A1 (en) * 2001-11-07 2007-11-15 Eidgenossische Technische Hochschule Zurich Synthetic Matrix for Controlled Cell Ingrowth and Tissue Regeneration
WO2003052091A1 (en) * 2001-12-18 2003-06-26 Eidgenossisch Technische Hochschule Zurich Growth factor modified protein matrices for tissue engineering
ATE531447T1 (de) * 2003-01-17 2011-11-15 Cornell Res Foundation Inc Injizierbare hydrogel-microsphären aus wässrigem zwei-phasen-system
FR2865737B1 (fr) * 2004-02-03 2006-03-31 Anteis Sa Gel reticule biocompatible
KR100699278B1 (ko) * 2005-05-12 2007-03-23 학교법인 포항공과대학교 수화젤레이터로 유용한 바이오틴-아미노산 결합체 및이로부터 제조된 수화젤
US20070212385A1 (en) * 2006-03-13 2007-09-13 David Nathaniel E Fluidic Tissue Augmentation Compositions and Methods
JP5683587B2 (ja) * 2009-07-30 2015-03-11 カービラン バイオサージェリー， インコーポレイテッド 修飾ヒアルロン酸ポリマー組成物および関連する方法
CN106913902A (zh) * 2009-11-09 2017-07-04 聚光灯技术合伙有限责任公司 多糖基水凝胶
AU2011311904B2 (en) * 2010-10-06 2016-02-25 President And Fellows Of Harvard College Injectable, pore-forming hydrogels for materials-based cell therapies
CN104271638B (zh) * 2012-03-16 2016-11-02 本德尔分析控股公司 源于亲核活性聚噁唑啉的交联聚合物和医用品
SI2916881T1 (sl) * 2012-11-07 2020-04-30 Eth Zurich Hidrogeli sulfiranih alginatov za celično kulturo in zdravljenje

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CY1124571T1 (el) 2022-07-22
DK3868416T3 (da) 2022-10-31
EP3347061A1 (en) 2018-07-18
CN108025110A (zh) 2018-05-11
CN113372579B (zh) 2023-07-14
EP3868416A1 (en) 2021-08-25
AU2016320395B2 (en) 2020-09-17
EP3347061B1 (en) 2021-05-19
IL257024A (en) 2018-03-29
JP2018535704A (ja) 2018-12-06
EP3868416B1 (en) 2022-08-10
RS62239B1 (sr) 2021-09-30
LT3347061T (lt) 2021-09-10
CN113372579A (zh) 2021-09-10
WO2017042301A1 (en) 2017-03-16
AU2016320395A1 (en) 2018-02-22
PT3347061T (pt) 2021-08-25
CN108025110B (zh) 2021-08-20
JP6829898B2 (ja) 2021-02-17
SI3347061T1 (sl) 2021-11-30
IL257024B (en) 2022-02-01
HUE055937T2 (hu) 2022-01-28
US20180264176A1 (en) 2018-09-20
PL3347061T3 (pl) 2021-11-22

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