DK3868416T3 - Injicerbare makroporøse hydrogeler - Google Patents

Injicerbare makroporøse hydrogeler Download PDF

Info

Publication number
DK3868416T3
DK3868416T3 DK21168993.0T DK21168993T DK3868416T3 DK 3868416 T3 DK3868416 T3 DK 3868416T3 DK 21168993 T DK21168993 T DK 21168993T DK 3868416 T3 DK3868416 T3 DK 3868416T3
Authority
DK
Denmark
Prior art keywords
macroporous hydrogels
injectable
injectable macroporous
hydrogels
macroporous
Prior art date
Application number
DK21168993.0T
Other languages
English (en)
Inventor
Marcy Zenobi-Wong
Nicolas Broguiere
Original Assignee
Eth Zuerich
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eth Zuerich filed Critical Eth Zuerich
Application granted granted Critical
Publication of DK3868416T3 publication Critical patent/DK3868416T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/26—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • C08G65/331—Polymers modified by chemical after-treatment with organic compounds containing oxygen
    • C08G65/332—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides, or esters thereof
    • C08G65/3322—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides, or esters thereof acyclic
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/02—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
    • C08J3/03—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
    • C08J3/075—Macromolecular gels
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
    • C08J9/28—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof by elimination of a liquid phase from a macromolecular composition or article, e.g. drying of coagulum
    • C08J9/286—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof by elimination of a liquid phase from a macromolecular composition or article, e.g. drying of coagulum the liquid phase being a solvent for the monomers but not for the resulting macromolecular composition, i.e. macroporous or macroreticular polymers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/02—Dextran; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L53/00—Compositions of block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
    • C08L71/02—Polyalkylene oxides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
    • C08L71/08—Polyethers derived from hydroxy compounds or from their metallic derivatives
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L79/00—Compositions of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing nitrogen with or without oxygen or carbon only, not provided for in groups C08L61/00 - C08L77/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/06—Flowable or injectable implant compositions
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2371/00—Characterised by the use of polyethers obtained by reactions forming an ether link in the main chain; Derivatives of such polymers
    • C08J2371/02—Polyalkylene oxides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2405/00—Characterised by the use of polysaccharides or of their derivatives not provided for in groups C08J2401/00 or C08J2403/00
    • C08J2405/02—Dextran; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2405/00—Characterised by the use of polysaccharides or of their derivatives not provided for in groups C08J2401/00 or C08J2403/00
    • C08J2405/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2201/00—Properties
    • C08L2201/54—Aqueous solutions or dispersions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Materials Engineering (AREA)
  • Zoology (AREA)
  • Botany (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
DK21168993.0T 2015-09-09 2016-09-08 Injicerbare makroporøse hydrogeler DK3868416T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15184552 2015-09-09
EP16763035.9A EP3347061B1 (en) 2015-09-09 2016-09-08 Injectable macroporous hydrogels

Publications (1)

Publication Number Publication Date
DK3868416T3 true DK3868416T3 (da) 2022-10-31

Family

ID=54150245

Family Applications (2)

Application Number Title Priority Date Filing Date
DK16763035.9T DK3347061T3 (da) 2015-09-09 2016-09-08 Injicerbare makroporøse hydrogeler
DK21168993.0T DK3868416T3 (da) 2015-09-09 2016-09-08 Injicerbare makroporøse hydrogeler

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK16763035.9T DK3347061T3 (da) 2015-09-09 2016-09-08 Injicerbare makroporøse hydrogeler

Country Status (18)

Country Link
US (1) US20180264176A1 (da)
EP (2) EP3868416B1 (da)
JP (1) JP6829898B2 (da)
CN (2) CN108025110B (da)
AU (1) AU2016320395B2 (da)
CA (1) CA2992692C (da)
CY (1) CY1124571T1 (da)
DK (2) DK3347061T3 (da)
ES (1) ES2883235T3 (da)
HR (1) HRP20211306T1 (da)
HU (1) HUE055937T2 (da)
IL (1) IL257024B (da)
LT (1) LT3347061T (da)
PL (1) PL3347061T3 (da)
PT (1) PT3347061T (da)
RS (1) RS62239B1 (da)
SI (1) SI3347061T1 (da)
WO (1) WO2017042301A1 (da)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3064403C (en) 2010-10-01 2022-06-21 Applied Medical Resources Corporation Portable laparoscopic trainer
US9218753B2 (en) 2011-10-21 2015-12-22 Applied Medical Resources Corporation Simulated tissue structure for surgical training
WO2013096632A1 (en) 2011-12-20 2013-06-27 Applied Medical Resources Corporation Advanced surgical simulation
EP2907125B1 (en) 2012-09-26 2017-08-02 Applied Medical Resources Corporation Surgical training model for laparoscopic procedures
US10679520B2 (en) 2012-09-27 2020-06-09 Applied Medical Resources Corporation Surgical training model for laparoscopic procedures
EP2901437B1 (en) 2012-09-27 2019-02-27 Applied Medical Resources Corporation Surgical training model for laparoscopic procedures
JP6482478B2 (ja) 2013-03-01 2019-03-13 アプライド メディカル リソーシーズ コーポレイション 手術シミュレーションシステム及び方法
CA3232626A1 (en) 2013-06-18 2014-12-24 Applied Medical Resources Corporation Gallbladder model
AU2014293036B2 (en) 2013-07-24 2017-12-21 Applied Medical Resources Corporation First entry model
US10198966B2 (en) 2013-07-24 2019-02-05 Applied Medical Resources Corporation Advanced first entry model for surgical simulation
CA2943197C (en) 2014-03-26 2023-04-11 Applied Medical Resources Corporation Simulated dissectible tissue
KR20240067288A (ko) 2014-11-13 2024-05-16 어플라이드 메디컬 리소시스 코포레이션 시뮬레이션된 조직 모델들 및 방법들
KR102674645B1 (ko) 2015-02-19 2024-06-12 어플라이드 메디컬 리소시스 코포레이션 시뮬레이션된 조직 구조체들 및 방법들
JP2018514805A (ja) 2015-05-14 2018-06-07 アプライド メディカル リソーシーズ コーポレイション 電気手術トレーニングおよびシミュレーション用の合成組織構造
AU2016276771B2 (en) 2015-06-09 2022-02-03 Applied Medical Resources Corporation Hysterectomy model
EP3748610A1 (en) 2015-07-16 2020-12-09 Applied Medical Resources Corporation Simulated dissectable tissue
AU2016297579B2 (en) 2015-07-22 2022-03-17 Applied Medical Resources Corporation Appendectomy model
KR20240037386A (ko) 2015-10-02 2024-03-21 어플라이드 메디컬 리소시스 코포레이션 자궁 절제술 모델
EP4235632A3 (en) 2015-11-20 2024-01-24 Applied Medical Resources Corporation Simulated dissectible tissue
EP3433282B1 (en) 2016-03-24 2022-07-13 Takeda Pharmaceutical Company Limited Alginate hydrogel compositions
JP6925579B2 (ja) * 2016-03-31 2021-08-25 日油株式会社 環状ベンジリデンアセタール構造を有する生分解性ヒドロゲル
WO2018005301A1 (en) 2016-06-27 2018-01-04 Applied Medical Resources Corporation Simulated abdominal wall
EP3554569A1 (en) * 2016-12-13 2019-10-23 Millennium Pharmaceuticals, Inc. Conformal coating of biological surfaces
AU2018220845B2 (en) 2017-02-14 2023-11-23 Applied Medical Resources Corporation Laparoscopic training system
US10847057B2 (en) 2017-02-23 2020-11-24 Applied Medical Resources Corporation Synthetic tissue structures for electrosurgical training and simulation
AU2018330610A1 (en) * 2017-09-11 2020-04-02 Evorion Biotechnologies Gmbh Systems, methods and hydrogels for cell culture and analysis
CN108893445A (zh) * 2018-07-26 2018-11-27 南方医科大学 一种引导视网膜神经节细胞及其轴突生长延展的方法
CN109316628B (zh) * 2018-09-21 2021-04-20 广州远想生物科技有限公司 一种凝胶及其制备方法和应用
CN109731133B (zh) * 2019-02-01 2020-09-01 浙江大学 一种抗菌、抗粘附、可注射式温敏壳聚糖凝胶敷料及其制备方法
US11680107B2 (en) * 2019-03-22 2023-06-20 Taipei Medical University Hydrogel composition for drug delivery and uses thereof
CN114222777B (zh) 2019-08-28 2024-05-14 波士顿科学国际有限公司 多臂聚恶唑啉和与其相关的组合物、系统和方法
EP4084802A4 (en) * 2020-01-03 2024-03-13 Repertoire Immune Medicines, Inc. COMPOSITIONS OF HYDROGELS AND METHODS OF USE THEREOF
CN112898600B (zh) * 2021-02-07 2023-05-23 西安工业大学 一种聚多巴胺可逆粘附凝胶的分相制备方法
WO2023135155A1 (en) 2022-01-12 2023-07-20 Eth Zurich Photocurable phase-separating hydrogels
WO2023242189A1 (en) 2022-06-13 2023-12-21 Eth Zurich Collagen visualization on microfluidic device

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070264227A1 (en) * 2001-11-07 2007-11-15 Eidgenossische Technische Hochschule Zurich Synthetic Matrix for Controlled Cell Ingrowth and Tissue Regeneration
AU2002363343B2 (en) * 2001-11-07 2008-07-24 Eidgenossische Technische Hochschule Zurich Synthetic matrix for controlled cell ingrowth and tissue regeneration
BRPI0215192B8 (pt) * 2001-12-18 2021-07-27 Eidgenoessische Technische Hochschule Zuerich peptídeo de fusão, kit e matriz que compreendem o mesmo, e método para criar uma matriz
CA2513483C (en) * 2003-01-17 2011-11-29 Cornell Research Foundation, Inc. Injectable hydrogel microspheres from aqueous two-phase system
FR2865737B1 (fr) * 2004-02-03 2006-03-31 Anteis Sa Gel reticule biocompatible
KR100699278B1 (ko) * 2005-05-12 2007-03-23 학교법인 포항공과대학교 수화젤레이터로 유용한 바이오틴-아미노산 결합체 및이로부터 제조된 수화젤
US20070212385A1 (en) * 2006-03-13 2007-09-13 David Nathaniel E Fluidic Tissue Augmentation Compositions and Methods
CN102573941B (zh) * 2009-07-30 2014-10-29 卡比兰生物外科公司 改性透明质酸聚合物组合物和相关的方法
NZ599524A (en) * 2009-11-09 2014-04-30 Spotlight Technology Partners Llc Polysaccharide based hydrogels
EP2624873B1 (en) * 2010-10-06 2019-12-04 President and Fellows of Harvard College Injectable, pore-forming hydrogels for materials-based cell therapies
US9416228B2 (en) * 2012-03-16 2016-08-16 Bender Analytical Holding B.V. Cross-linked polymers and medical products derived from nucleophilically activated polyoxazoline
WO2014072035A1 (en) * 2012-11-07 2014-05-15 Eth Zurich Sulfated alginate hydrogels for cell culture and therapy

Also Published As

Publication number Publication date
IL257024B (en) 2022-02-01
US20180264176A1 (en) 2018-09-20
JP6829898B2 (ja) 2021-02-17
EP3868416B1 (en) 2022-08-10
HUE055937T2 (hu) 2022-01-28
DK3347061T3 (da) 2021-08-23
AU2016320395B2 (en) 2020-09-17
WO2017042301A1 (en) 2017-03-16
AU2016320395A1 (en) 2018-02-22
CN108025110A (zh) 2018-05-11
CY1124571T1 (el) 2022-07-22
HRP20211306T1 (hr) 2021-11-26
CN108025110B (zh) 2021-08-20
CN113372579A (zh) 2021-09-10
PL3347061T3 (pl) 2021-11-22
CN113372579B (zh) 2023-07-14
CA2992692C (en) 2021-12-21
CA2992692A1 (en) 2017-03-16
JP2018535704A (ja) 2018-12-06
SI3347061T1 (sl) 2021-11-30
IL257024A (en) 2018-03-29
EP3868416A1 (en) 2021-08-25
EP3347061B1 (en) 2021-05-19
PT3347061T (pt) 2021-08-25
EP3347061A1 (en) 2018-07-18
RS62239B1 (sr) 2021-09-30
LT3347061T (lt) 2021-09-10
ES2883235T3 (es) 2021-12-07

Similar Documents

Publication Publication Date Title
DK3868416T3 (da) Injicerbare makroporøse hydrogeler
NO2023007I1 (no) Vutrisiran
DK3283625T3 (da) Nukleasemedieret genomeditering
DK3331869T3 (da) Muscarinagonister
DK3305788T3 (da) Janus-kinase-hæmmer
DK4032440T3 (da) Låganordning
DK3277719T3 (da) Polypeptider
DK3331528T3 (da) Muskarinagonister
DK3360890T3 (da) Genterapi
CL2015001896S1 (es) Vehiculo
DK3331529T3 (da) Muskarinagonister
DK3310450T3 (da) Olie-vand-separator
DK3270930T3 (da) Præeklampsi
DK3256546T3 (da) Depolymeriseringsfremgangsmåde
DK3394281T3 (da) Gærcelle
DK3292136T3 (da) Penicillin-g-acylaser
DK3274482T3 (da) Stenborsknop
DE112015006486A5 (de) Inkubationsrinne
DK3318308T3 (da) Badmintonketsjer
DE112015005906A5 (de) Gurtschlossbringer
ES1140083Y (es) Descompatactador tetrafunción
DE102015206660A8 (de) Plattenaufteilanlage
BR112018004842A2 (pt) Veículo
DE112016001124A5 (de) Spannschutz
ES1142709Y (es) Vehiculo quitanieves