DK3347015T3 - Fremgangsmåder til diagnosticering og behandling af adfærdsforstyrrelser - Google Patents

Fremgangsmåder til diagnosticering og behandling af adfærdsforstyrrelser Download PDF

Info

Publication number
DK3347015T3
DK3347015T3 DK16767115.5T DK16767115T DK3347015T3 DK 3347015 T3 DK3347015 T3 DK 3347015T3 DK 16767115 T DK16767115 T DK 16767115T DK 3347015 T3 DK3347015 T3 DK 3347015T3
Authority
DK
Denmark
Prior art keywords
diagnosing
methods
behavioral disorders
treating behavioral
treating
Prior art date
Application number
DK16767115.5T
Other languages
English (en)
Inventor
Hakon Hakonarson
Charlly Kao
Original Assignee
Childrens Hospital Philadelphia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Childrens Hospital Philadelphia filed Critical Childrens Hospital Philadelphia
Application granted granted Critical
Publication of DK3347015T3 publication Critical patent/DK3347015T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
DK16767115.5T 2015-09-08 2016-09-07 Fremgangsmåder til diagnosticering og behandling af adfærdsforstyrrelser DK3347015T3 (da)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562215636P 2015-09-08 2015-09-08
US201562215628P 2015-09-08 2015-09-08
US201562215673P 2015-09-08 2015-09-08
US201562215633P 2015-09-08 2015-09-08
PCT/US2016/050580 WO2017044502A1 (en) 2015-09-08 2016-09-07 Methods of diagnosing and treating conduct disorder

Publications (1)

Publication Number Publication Date
DK3347015T3 true DK3347015T3 (da) 2021-12-06

Family

ID=56943962

Family Applications (4)

Application Number Title Priority Date Filing Date
DK16767115.5T DK3347015T3 (da) 2015-09-08 2016-09-07 Fremgangsmåder til diagnosticering og behandling af adfærdsforstyrrelser
DK16771034.2T DK3347016T3 (da) 2015-09-08 2016-09-07 Diagnosticering og behandling af angstlidelse
DK16767112.2T DK3347013T3 (da) 2015-09-08 2016-09-07 Ikke-selektive metabotropiske glutamatreceptoraktivatorer til behandling af opmærksomhedsforstyrrelse og 22q-syndrom
DK16767114.8T DK3347014T3 (da) 2015-09-08 2016-09-07 Fremgangsmåder til diagnosticering og behandling af Tourettes syndrom

Family Applications After (3)

Application Number Title Priority Date Filing Date
DK16771034.2T DK3347016T3 (da) 2015-09-08 2016-09-07 Diagnosticering og behandling af angstlidelse
DK16767112.2T DK3347013T3 (da) 2015-09-08 2016-09-07 Ikke-selektive metabotropiske glutamatreceptoraktivatorer til behandling af opmærksomhedsforstyrrelse og 22q-syndrom
DK16767114.8T DK3347014T3 (da) 2015-09-08 2016-09-07 Fremgangsmåder til diagnosticering og behandling af Tourettes syndrom

Country Status (12)

Country Link
US (12) US20170087139A1 (da)
EP (9) EP4342493A2 (da)
JP (8) JP7152306B2 (da)
CN (7) CN108348518A (da)
AU (8) AU2016318775B2 (da)
CA (5) CA2997187C (da)
DK (4) DK3347015T3 (da)
ES (4) ES2876898T3 (da)
HK (4) HK1258446A1 (da)
IL (10) IL290993B2 (da)
SG (1) SG10202012842SA (da)
WO (4) WO2017044497A1 (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2686300T3 (es) 2010-08-24 2018-10-17 The Children's Hospital Of Philadelphia Asociación de variaciones genéticas raras recurrentes con el trastorno por déficit de atención e hiperactividad (TDAH) y procedimientos de uso de las mismas para el diagnóstico y tratamiento del mismo
WO2017044497A1 (en) * 2015-09-08 2017-03-16 The Children's Hospital Of Philadelphia Methods of diagnosing and treating tourette syndrome
US20200143922A1 (en) * 2016-06-03 2020-05-07 Yale University Methods and apparatus for predicting depression treatment outcomes
WO2018048868A1 (en) * 2016-09-07 2018-03-15 The Children's Hospital Of Philadelphia Nonselective metabotropic glutamate receptor activators for treatment of anorexia nervosa and binge eating disorder
US11684617B2 (en) 2017-04-19 2023-06-27 The Children's Hospital Of Philadelphia Methods of diagnosing and treating ADHD in biomarker positive subjects
WO2018209328A1 (en) * 2017-05-11 2018-11-15 Miwa Julie M Compositions and methods for treating lynx2 disorders
CN107483425B (zh) * 2017-08-08 2020-12-18 北京盛华安信息技术有限公司 基于攻击链的复合攻击检测方法
SG11202006813TA (en) * 2018-01-18 2020-08-28 Childrens Hospital Philadelphia Fasoracetam crystalline forms
TW201932453A (zh) * 2018-01-18 2019-08-16 美商艾維基因醫學股份有限公司 法索西坦(fasoracetam)之固體型態
KR102250063B1 (ko) * 2019-06-14 2021-05-12 한국생명공학연구원 뚜렛증후군의 원인 유전자를 동정하는 방법
CN110955751A (zh) * 2019-11-13 2020-04-03 广州供电局有限公司 工作票文本去重方法、装置、系统及计算机存储介质
CA3170698A1 (en) * 2020-09-21 2022-03-24 Reveragen Biopharma, Inc. Vamorolone for the treatment of muscular dystrophy
WO2022065518A1 (ja) * 2020-09-23 2022-03-31 国立大学法人京都大学 神経突起伸長促進剤
CN117594119A (zh) * 2024-01-17 2024-02-23 北京大学第六医院 用于预测帕罗西汀或其药用盐对抑郁或焦虑症患者疗效的装置

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002067931A1 (en) * 2001-02-23 2002-09-06 Johns Hopkins University Treatment of tics, tremors and related disorders
CA2471198A1 (en) 2001-12-20 2003-07-03 Merck & Co., Inc. Identification of novel polymorphic sites in the human mglur8 gene and uses thereof
JP2007530591A (ja) 2004-03-25 2007-11-01 スミスクライン・ビーチャム・コーポレイション 双極性障害を治療するための、nk3アンタゴニストの使用
AU2007223036A1 (en) 2006-03-08 2007-09-13 Braincells, Inc. Modulation of neurogenesis by nootropic agents
US20100216734A1 (en) * 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
TW200819458A (en) 2006-06-23 2008-05-01 Merz Pharma Gmbh & Co Kgaa Metabotropic glutamate receptor modulators
EP2118320A4 (en) 2007-02-06 2010-05-19 Genizon Biosciences Inc GENE CARD OF HUMAN GENES ASSOCIATED WITH HYPERACTIVITY ATTENTION DEFICIT DISORDER (ADHD)
WO2008136996A2 (en) 2007-04-30 2008-11-13 The Ohio State University Research Foundation Polymorphisms in genes affecting ace-related disorders and uses thereof
US20090176740A1 (en) 2007-11-30 2009-07-09 Phillips Ii Dauglas James Treatment of neurological conditions by the co-administration of aniracetam and l-alpha glycerylphosphorylcholine
WO2009105718A1 (en) 2008-02-20 2009-08-27 The Children's Hospital Of Philadelphia Genetic alterations associated with autism and the autistic phenotype and methods of use thereof for the diagnosis and treatmemt of autism
WO2010057132A1 (en) 2008-11-14 2010-05-20 The Children's Hospital Of Philadelphia Genetic alterations associated with schizophrenia and methods of use thereof for the diagnosis and treatment of the same
US20110311512A1 (en) 2008-11-14 2011-12-22 Hakon Hakonarson Genetic Variants Underlying Human Cognition and Methods of Use Thereof as Diagnostic and Therapeutic Targets
EP2470527A4 (en) 2009-08-20 2013-02-27 Merck Sharp & Dohme BENZOTRIAZOLE D ETHER DERIVATIVES
US8714471B2 (en) * 2010-07-29 2014-05-06 Brady Worldwide, Inc. Friction core brake
ES2686300T3 (es) 2010-08-24 2018-10-17 The Children's Hospital Of Philadelphia Asociación de variaciones genéticas raras recurrentes con el trastorno por déficit de atención e hiperactividad (TDAH) y procedimientos de uso de las mismas para el diagnóstico y tratamiento del mismo
US20130225623A1 (en) 2010-10-27 2013-08-29 Mount Sinai School Of Medicine Methods of Treating Psychiatric or Neurological Disorders with MGLUR Antagonists
WO2013006857A1 (en) 2011-07-07 2013-01-10 The Children's Hospital Of Philadelphia Genetic alterations associated with autism and the autistic phenotype and methods of use thereof for the diagnosis and treatment of autism
US20130143867A1 (en) * 2011-12-02 2013-06-06 Sychroneuron Inc. Acamprosate formulations, methods of using the same, and combinations comprising the same
AU2013305580A1 (en) * 2012-08-23 2015-04-09 Stuart L. Weg Anxiolytic composition, formulation and method of use
US9346239B2 (en) 2012-09-26 2016-05-24 Eastman Kodak Company Method for providing patterns of functional materials
WO2014152965A2 (en) 2013-03-14 2014-09-25 The Children's Hospital Of Philadelphia Schizophrenia-associated genetic loci identified in genome wide association studies and use thereof as novel therapeutic targets
EP3149211A1 (en) 2014-05-30 2017-04-05 The Children's Hospital of Philadelphia Genetic alterations associated with autism and autistic phenotype and methods of diagnosing and treating autism
US11219617B2 (en) 2014-05-30 2022-01-11 The Children's Hospital Of Philadelphia Methods of diagnosing and treating autism
KR102232583B1 (ko) 2015-01-08 2021-03-26 삼성전자주식회사 전자장치 및 전자장치의 웹 재현 방법
EP3307913A4 (en) 2015-06-15 2019-03-27 The Children's Hospital of Philadelphia METHOD FOR DIAGNOSIS AND TREATMENT OF AUTISM
WO2017044497A1 (en) 2015-09-08 2017-03-16 The Children's Hospital Of Philadelphia Methods of diagnosing and treating tourette syndrome

Also Published As

Publication number Publication date
AU2022205142A1 (en) 2022-07-28
AU2022204324A1 (en) 2022-07-07
AU2016318786B2 (en) 2022-04-07
CN108348518A (zh) 2018-07-31
CN116919961A (zh) 2023-10-24
JP2023051937A (ja) 2023-04-11
CA2997189A1 (en) 2017-03-16
HK1258373A1 (zh) 2019-11-08
ES2876898T3 (es) 2021-11-15
WO2017044503A1 (en) 2017-03-16
IL257785A (en) 2018-06-28
CN115919852A (zh) 2023-04-07
IL300474A (en) 2023-04-01
WO2017044491A1 (en) 2017-03-16
EP3347014B1 (en) 2021-10-20
US20210205288A1 (en) 2021-07-08
EP4342493A2 (en) 2024-03-27
EP3922249A1 (en) 2021-12-15
JP2018526398A (ja) 2018-09-13
JP7281280B2 (ja) 2023-05-25
JP2023011558A (ja) 2023-01-24
AU2016318775A1 (en) 2018-04-12
IL257746A (en) 2018-06-28
IL303605A (en) 2023-08-01
AU2016318780A1 (en) 2018-04-12
AU2016318785A1 (en) 2018-04-12
EP3347016B1 (en) 2021-04-28
CN108495630A (zh) 2018-09-04
JP7027308B2 (ja) 2022-03-01
EP3964213A1 (en) 2022-03-09
CA2997188A1 (en) 2017-03-16
CA2997187A1 (en) 2017-03-16
IL257744B (en) 2022-04-01
DK3347013T3 (da) 2022-04-04
US10869861B2 (en) 2020-12-22
US20180110767A1 (en) 2018-04-26
JP2018526395A (ja) 2018-09-13
US20220117954A1 (en) 2022-04-21
WO2017044502A1 (en) 2017-03-16
US11298347B2 (en) 2022-04-12
US11179378B2 (en) 2021-11-23
AU2016318785B2 (en) 2022-04-14
AU2016318786A1 (en) 2018-04-12
EP3964213B1 (en) 2024-03-13
AU2016318775B2 (en) 2022-02-10
EP3922249B1 (en) 2024-02-28
AU2022204355A1 (en) 2022-07-14
IL290992B2 (en) 2023-07-01
IL257744A (en) 2018-06-28
DK3347016T3 (da) 2021-07-12
WO2017044497A1 (en) 2017-03-16
IL290985A (en) 2022-05-01
US20170087139A1 (en) 2017-03-30
EP3347015A1 (en) 2018-07-18
JP2018526396A (ja) 2018-09-13
JP7152306B2 (ja) 2022-10-12
EP3977996B1 (en) 2024-03-13
US20170087140A1 (en) 2017-03-30
JP7281279B2 (ja) 2023-05-25
JP2018526394A (ja) 2018-09-13
EP4023222A1 (en) 2022-07-06
IL257746B (en) 2022-04-01
US20220296582A1 (en) 2022-09-22
CA3225374A1 (en) 2017-03-16
US11806341B2 (en) 2023-11-07
IL290993A (en) 2022-05-01
IL290992B1 (en) 2023-03-01
AU2022203039A1 (en) 2022-05-26
IL257747A (en) 2018-06-28
US11173153B2 (en) 2021-11-16
DK3347014T3 (da) 2021-12-06
IL290994A (en) 2022-05-01
ES2909329T3 (es) 2022-05-06
US20200306237A1 (en) 2020-10-01
IL290993B1 (en) 2023-07-01
JP2022078104A (ja) 2022-05-24
IL257747B (en) 2022-04-01
CA2997191A1 (en) 2017-03-16
US20240100036A1 (en) 2024-03-28
CN108348517B (zh) 2021-11-05
US20240075022A1 (en) 2024-03-07
EP3977996A1 (en) 2022-04-06
ES2898932T3 (es) 2022-03-09
JP2023036671A (ja) 2023-03-14
HK1258447A1 (zh) 2019-11-15
EP3347013B1 (en) 2022-02-16
EP3347015B1 (en) 2021-10-20
IL290992A (en) 2022-05-01
CN108348517A (zh) 2018-07-31
IL257785B (en) 2022-04-01
IL290993B2 (en) 2023-11-01
AU2016318780B2 (en) 2022-04-07
CA2997187C (en) 2024-02-20
US11806340B2 (en) 2023-11-07
CN108601776A (zh) 2018-09-28
ES2897953T3 (es) 2022-03-03
US20170087141A1 (en) 2017-03-30
SG10202012842SA (en) 2021-01-28
US20220117953A1 (en) 2022-04-21
US20170105985A1 (en) 2017-04-20
EP3347013A1 (en) 2018-07-18
CN116919962A (zh) 2023-10-24
EP3347014A1 (en) 2018-07-18
HK1258448A1 (zh) 2019-11-15
US9884057B2 (en) 2018-02-06
HK1258446A1 (zh) 2019-11-15
EP3347016A1 (en) 2018-07-18

Similar Documents

Publication Publication Date Title
DK3347015T3 (da) Fremgangsmåder til diagnosticering og behandling af adfærdsforstyrrelser
DK3206493T3 (da) Sammensætninger og fremgangsmåder til behandling af cns-forstyrrelser
DK3374163T3 (da) Additivfremstillingsanordning, system og fremgangsmåde
DK3280441T3 (da) Anti-sortilin-antistoffer og fremgangsmåder til anvendelse deraf
DK3227336T3 (da) Anti-CD79b-antistoffer og fremgangsmåder til anvendelse
DK3888658T3 (da) Eif4-a-inhiberende forbindelser og fremgangsmåder relateret dertil
DK3114540T3 (da) Neuralt netværk og fremgangsmåder til træning af neuralt netværk
DK3185876T3 (da) Sammensætninger og fremgangsmåder til behandling af neurologiske lidelser
DK3265947T3 (da) Fremgangsmåde og system til kryptering
DK3201351T3 (da) Kaloriefrie sødestoffer og fremgangsmåder til syntetisering
DK3286311T3 (da) Fremgangsmåde til behandling af maligniteter
DK3250210T3 (da) Sammensætninger og fremgangsmåder til behandling af cns-forstyrrelser
DK3102673T3 (da) Fremgangsmåder og sammensætninger til behandling af beta-talassæmi
DK3319612T3 (da) Oxysteroler og fremgansmåder til anvendelse derfor
DK3215147T3 (da) Neurodæmpende norketamin-forbindelser og fremgangsmåder
BR112016026939A2 (pt) aparelho e método.
DK3339479T3 (da) Elektrolyseindretning og elektrolysefremgangsmåde
DK3285782T3 (da) Fremgangsmåder til vævsreparation og -regenerering
DK3633683T3 (da) Fremgangsmåde til at fusionere og komprimere kompakte tori
DK3539469T3 (da) System og fremgangsmåde til overvågning af bækkenbundsmusklerne
DK3174489T3 (da) Metode og anordning til at læsse
BR112016027102A2 (pt) método e aparelho
DK3265087T3 (da) Fremgangsmåde til behandling med tradipitant
DK3110446T3 (da) Fremgangsmåder og sammensætninger til behandling af Siglec-8-associerede sygdomme
KR20180084959A (ko) 파면 분석을 위한 디바이스 및 방법