DK3338891T3 - En fremgangsmåde til at detektere genetisk materiale i en biologisk prøve og en indretning til implementering deraf - Google Patents
En fremgangsmåde til at detektere genetisk materiale i en biologisk prøve og en indretning til implementering deraf Download PDFInfo
- Publication number
- DK3338891T3 DK3338891T3 DK17002043.2T DK17002043T DK3338891T3 DK 3338891 T3 DK3338891 T3 DK 3338891T3 DK 17002043 T DK17002043 T DK 17002043T DK 3338891 T3 DK3338891 T3 DK 3338891T3
- Authority
- DK
- Denmark
- Prior art keywords
- implementing
- procedure
- biological sample
- genetic material
- detecting genetic
- Prior art date
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
- B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/6895—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/702—Specific hybridization probes for retroviruses
- C12Q1/703—Viruses associated with AIDS
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0605—Metering of fluids
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0663—Whole sensors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0672—Integrated piercing tool
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/16—Surface properties and coatings
- B01L2300/161—Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
- B01L2300/165—Specific details about hydrophobic, oleophobic surfaces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1861—Means for temperature control using radiation
- B01L2300/1872—Infrared light
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
- G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/06—Illumination; Optics
- G01N2201/062—LED's
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Clinical Laboratory Science (AREA)
- Virology (AREA)
- Hematology (AREA)
- Dispersion Chemistry (AREA)
- Botany (AREA)
- Mycology (AREA)
- AIDS & HIV (AREA)
- Optics & Photonics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PL419907A PL235210B1 (pl) | 2016-12-21 | 2016-12-21 | Sposób detekcji materiału genetycznego w próbce biologicznej oraz urządzenie do jego realizacji |
Publications (1)
Publication Number | Publication Date |
---|---|
DK3338891T3 true DK3338891T3 (da) | 2022-04-25 |
Family
ID=60953514
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK17002043.2T DK3338891T3 (da) | 2016-12-21 | 2017-12-20 | En fremgangsmåde til at detektere genetisk materiale i en biologisk prøve og en indretning til implementering deraf |
Country Status (16)
Country | Link |
---|---|
US (2) | US10781479B2 (da) |
EP (2) | EP3338891B8 (da) |
JP (1) | JP6961700B2 (da) |
CN (1) | CN110088266A (da) |
BR (1) | BR112019012501B1 (da) |
CA (1) | CA2989599C (da) |
DK (1) | DK3338891T3 (da) |
ES (1) | ES2913092T3 (da) |
HR (1) | HRP20220582T1 (da) |
HU (1) | HUE058240T2 (da) |
LT (1) | LT3338891T (da) |
PL (1) | PL235210B1 (da) |
PT (1) | PT3338891T (da) |
RS (1) | RS63179B1 (da) |
SI (1) | SI3338891T1 (da) |
WO (1) | WO2018117882A1 (da) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2022034867A1 (ja) * | 2020-08-11 | 2022-02-17 | 杏林製薬株式会社 | 核酸増幅装置、核酸増幅方法及び試料溶液位置制御方法 |
CN115290606A (zh) * | 2022-08-22 | 2022-11-04 | 凤凰医学诊断科技有限公司 | 一种检测装置 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6780617B2 (en) * | 2000-12-29 | 2004-08-24 | Chen & Chen, Llc | Sample processing device and method |
US20030138819A1 (en) * | 2001-10-26 | 2003-07-24 | Haiqing Gong | Method for detecting disease |
US20090061450A1 (en) | 2006-03-14 | 2009-03-05 | Micronics, Inc. | System and method for diagnosis of infectious diseases |
WO2008134462A1 (en) * | 2007-04-25 | 2008-11-06 | 3M Innovative Properties Company | Supported reagents, methods, and devices |
US9447461B2 (en) | 2009-03-24 | 2016-09-20 | California Institute Of Technology | Analysis devices, kits, and related methods for digital quantification of nucleic acids and other analytes |
WO2010110741A1 (en) * | 2009-03-25 | 2010-09-30 | Haiqing Gong | Apparatus and method for detection of organisms |
FR2950358B1 (fr) * | 2009-09-18 | 2015-09-11 | Biomerieux Sa | Dispositif d'amplification d'acides nucleiques simplifie et son procede de mise en oeuvre |
EP2539426B1 (en) | 2010-02-23 | 2016-11-09 | Luminex Corporation | Apparatus for integrated sample preparation, reaction and detection |
US20110312772A1 (en) * | 2010-06-17 | 2011-12-22 | Geneasys Pty Ltd | Loc for detection of hybridization of nucleic acid sequences with pcr amplification using linker primers |
CN104066849B (zh) * | 2011-10-11 | 2017-04-19 | 凯杰有限公司 | 样品处理方法和样品处理盒 |
EP2962092A4 (en) * | 2013-03-01 | 2016-08-24 | Wave 80 Biosciences Inc | METHODS AND SYSTEMS FOR ENHANCED MICRO-FLUIDIC TREATMENT |
US10933417B2 (en) | 2013-03-15 | 2021-03-02 | Nanobiosym, Inc. | Systems and methods for mobile device analysis of nucleic acids and proteins |
EP3154693B1 (en) * | 2014-06-11 | 2021-11-03 | PerkinElmer Health Sciences, Inc. | Method for performing a sample assay with a microfluidic cartridges with integrated assay controls |
CA2991918A1 (en) * | 2014-07-11 | 2016-01-14 | Advanced Theranostics Inc. | Point of care polymerase chain reaction device for disease detection |
WO2016115542A1 (en) * | 2015-01-16 | 2016-07-21 | The Regents Of The University Of California | Led driven plasmonic heating apparatus for nucleic acids amplification |
SG10202005427PA (en) | 2015-04-24 | 2020-07-29 | Mesa Biotech Inc | Fluidic test cassette |
CA3011710A1 (en) * | 2016-01-20 | 2017-07-27 | Triv Tech, Llc | Point-of-care nucleic acid amplification and detection |
JP7453664B2 (ja) * | 2016-10-11 | 2024-03-21 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 統合的分子診断システム(iMDx)およびデング熱のための方法 |
-
2016
- 2016-12-21 PL PL419907A patent/PL235210B1/pl unknown
-
2017
- 2017-12-20 JP JP2019534892A patent/JP6961700B2/ja active Active
- 2017-12-20 RS RS20220414A patent/RS63179B1/sr unknown
- 2017-12-20 WO PCT/PL2017/050065 patent/WO2018117882A1/en active Application Filing
- 2017-12-20 DK DK17002043.2T patent/DK3338891T3/da active
- 2017-12-20 ES ES17002043T patent/ES2913092T3/es active Active
- 2017-12-20 PT PT170020432T patent/PT3338891T/pt unknown
- 2017-12-20 EP EP17002043.2A patent/EP3338891B8/en active Active
- 2017-12-20 CA CA2989599A patent/CA2989599C/en active Active
- 2017-12-20 HU HUE17002043A patent/HUE058240T2/hu unknown
- 2017-12-20 SI SI201731139T patent/SI3338891T1/sl unknown
- 2017-12-20 BR BR112019012501-9A patent/BR112019012501B1/pt active IP Right Grant
- 2017-12-20 LT LTEP17002043.2T patent/LT3338891T/lt unknown
- 2017-12-20 EP EP22155747.3A patent/EP4029607A1/en active Pending
- 2017-12-20 CN CN201780078465.0A patent/CN110088266A/zh active Pending
- 2017-12-20 HR HRP20220582TT patent/HRP20220582T1/hr unknown
- 2017-12-21 US US15/850,733 patent/US10781479B2/en active Active
-
2020
- 2020-08-25 US US17/002,321 patent/US11608521B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
ES2913092T3 (es) | 2022-05-31 |
PL235210B1 (pl) | 2020-06-15 |
EP3338891B1 (en) | 2022-02-09 |
HRP20220582T1 (hr) | 2022-06-10 |
PT3338891T (pt) | 2022-05-16 |
LT3338891T (lt) | 2022-05-10 |
HUE058240T2 (hu) | 2022-07-28 |
SI3338891T1 (sl) | 2022-06-30 |
JP6961700B2 (ja) | 2021-11-05 |
EP4029607A1 (en) | 2022-07-20 |
CA2989599C (en) | 2024-04-02 |
US20180187250A1 (en) | 2018-07-05 |
EP3338891A1 (en) | 2018-06-27 |
US10781479B2 (en) | 2020-09-22 |
BR112019012501A2 (pt) | 2020-04-14 |
BR112019012501B1 (pt) | 2023-01-24 |
WO2018117882A1 (en) | 2018-06-28 |
CA2989599A1 (en) | 2018-06-21 |
JP2020513762A (ja) | 2020-05-21 |
RS63179B1 (sr) | 2022-06-30 |
PL419907A1 (pl) | 2018-07-02 |
US20210040549A1 (en) | 2021-02-11 |
EP3338891B8 (en) | 2022-03-16 |
US11608521B2 (en) | 2023-03-21 |
CN110088266A (zh) | 2019-08-02 |
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