DK3327113T3 - Forbedret svampeselektion - Google Patents

Forbedret svampeselektion Download PDF

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Publication number
DK3327113T3
DK3327113T3 DK17200169.5T DK17200169T DK3327113T3 DK 3327113 T3 DK3327113 T3 DK 3327113T3 DK 17200169 T DK17200169 T DK 17200169T DK 3327113 T3 DK3327113 T3 DK 3327113T3
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DK
Denmark
Prior art keywords
improved mushroom
selection
mushroom selection
improved
mushroom
Prior art date
Application number
DK17200169.5T
Other languages
Danish (da)
English (en)
Inventor
Carsten Lillelund Olsen
Original Assignee
Novozymes As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Novozymes As filed Critical Novozymes As
Application granted granted Critical
Publication of DK3327113T3 publication Critical patent/DK3327113T3/da

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0044—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on other nitrogen compounds as donors (1.7)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C12N9/20—Triglyceride splitting, e.g. by means of lipase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y107/00—Oxidoreductases acting on other nitrogenous compounds as donors (1.7)
    • C12Y107/01—Oxidoreductases acting on other nitrogenous compounds as donors (1.7) with NAD+ or NADP+ as acceptor (1.7.1)
    • C12Y107/01003—Nitrate reductase (NADPH) (1.7.1.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y107/00—Oxidoreductases acting on other nitrogenous compounds as donors (1.7)
    • C12Y107/01—Oxidoreductases acting on other nitrogenous compounds as donors (1.7) with NAD+ or NADP+ as acceptor (1.7.1)
    • C12Y107/01004—Nitrite reductase [NAD(P)H] (1.7.1.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/01—Hydro-lyases (4.2.1)
    • C12Y402/01011—Phosphopyruvate hydratase (4.2.1.11), i.e. enolase

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK17200169.5T 2012-05-31 2013-05-29 Forbedret svampeselektion DK3327113T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12170260 2012-05-31
EP13726188.9A EP2855659A1 (en) 2012-05-31 2013-05-29 Improved selection in fungi

Publications (1)

Publication Number Publication Date
DK3327113T3 true DK3327113T3 (da) 2021-09-13

Family

ID=48539153

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17200169.5T DK3327113T3 (da) 2012-05-31 2013-05-29 Forbedret svampeselektion

Country Status (7)

Country Link
US (3) US9487767B2 (enExample)
EP (2) EP2855659A1 (enExample)
JP (1) JP6449763B2 (enExample)
CN (1) CN104395454B (enExample)
BR (1) BR112014029252B8 (enExample)
DK (1) DK3327113T3 (enExample)
WO (1) WO2013178674A1 (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160348035A1 (en) 2014-03-05 2016-12-01 Novozymes A/S Compositions and Methods for Improving Properties of Non-Cellulosic Textile Materials with Xyloglucan Endotransglycosylase
EP3113609B1 (en) 2014-03-05 2019-07-31 Novozymes A/S Methods for improving post-harvest properties of agricultural crops
CN106062271A (zh) 2014-03-05 2016-10-26 诺维信公司 用于改进具有木葡聚糖内糖基转移酶的纤维素纺织材料的性质的组合物和方法
US20170073890A1 (en) 2014-03-05 2017-03-16 Novozymes A/S Compositions and Methods for Functionalizing and Linking Materials
EP3113611A1 (en) 2014-03-05 2017-01-11 Novozymes A/S Formulations comprising polymeric xyloglucan as a carrier for agriculturally beneficial agents
EP3183339A1 (en) 2014-08-20 2017-06-28 Novozymes A/S Xyloglucan endotransglycosylase variants and polynucleotides encoding same
EP3227438B1 (en) 2014-12-02 2024-03-27 Novozymes A/S Laccase variants and polynucleotides encoding same
RS61924B1 (sr) 2015-02-02 2021-06-30 Meiragtx Uk Ii Ltd Regulacija genske ekspresije putem aptamerom posredovane modulacije alternativnog splajsovanja
EP3274461A1 (en) * 2015-03-27 2018-01-31 Cargill, Incorporated Glucoamylase-modified yeast strains and methods for bioproduct production
WO2016174258A1 (en) 2015-04-29 2016-11-03 Boehringer Ingelheim Rcv Gmbh & Co Kg Means and methods for protein production
CA3007420A1 (en) 2015-12-17 2017-06-22 Cargill, Incorporated Sugar transporter-modified yeast strains and methods for bioproduct production
AU2017306657B2 (en) * 2016-08-03 2022-12-08 MeiraGTx Gene Regulation Limited High throughput cell-based screening for aptamers
CN109661403A (zh) 2016-08-05 2019-04-19 嘉吉公司 前导序列修饰的葡糖淀粉酶多肽和具有增强的生物产物产生的工程化的酵母菌株
CN108949579B (zh) * 2018-04-19 2021-10-01 中国科学技术大学 嗜热子囊菌基因表达系统
US12398411B2 (en) 2018-06-15 2025-08-26 Kikkoman Corporation Method for producing selenoneine
CN112585267B (zh) 2018-08-02 2024-07-12 诺维信公司 使用内含子制备dna构建体的组合文库
FI3898985T3 (fi) 2018-12-21 2023-05-05 Novozymes As Proteiinien tandemekspressio
CN110592149B (zh) * 2019-07-16 2020-07-14 甘肃省科学院生物研究所 一种梨囊鞭菌发酵秸秆生产乳酸的新方法和应用
US20220267783A1 (en) 2019-07-25 2022-08-25 Novozymes A/S Filamentous fungal expression system
US11479779B2 (en) * 2020-07-31 2022-10-25 Zymergen Inc. Systems and methods for high-throughput automated strain generation for non-sporulating fungi
CN114292761B (zh) * 2021-12-02 2023-11-03 南京工业大学 一株黑曲霉基因工程菌及构建方法与应用
WO2025133003A2 (en) 2023-12-19 2025-06-26 21St.Bio A/S Non-animal bovine beta lactoglobulin
WO2025140482A1 (zh) * 2023-12-28 2025-07-03 南京百斯杰生物工程有限公司 可改善目标多肽表达效果的多核苷酸构建体及其应用
WO2025226596A1 (en) 2024-04-24 2025-10-30 Novozymes A/S Methods for producing secreted polypeptides

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK122686D0 (da) 1986-03-17 1986-03-17 Novo Industri As Fremstilling af proteiner
FR2704860B1 (fr) 1993-05-05 1995-07-13 Pasteur Institut Sequences de nucleotides du locus cryiiia pour le controle de l'expression de sequences d'adn dans un hote cellulaire.
CN1192108C (zh) 1994-06-03 2005-03-09 诺沃奇梅兹生物技术有限公司 纯化的毁丝霉属漆酶及编码该酶的核酸
WO1996000787A1 (en) 1994-06-30 1996-01-11 Novo Nordisk Biotech, Inc. Non-toxic, non-toxigenic, non-pathogenic fusarium expression system and promoters and terminators for use therein
EP0966521A1 (en) 1996-09-13 1999-12-29 Novo Nordisk Biotech, Inc. Cells having dna insertion mutations which produce altered amounts of a polypeptide
CN1197965C (zh) 1998-10-26 2005-04-20 诺维信公司 在丝状真菌细胞内构建和筛选目的dna文库
AU4025700A (en) 1999-03-22 2000-10-09 Novo Nordisk Biotech, Inc. Promoters for expressing genes in a fungal cell
US6762040B2 (en) 2000-05-24 2004-07-13 Novozymes A/S Method for increasing gene copy number in a host cell and resulting host cell
JP2007259787A (ja) * 2006-03-29 2007-10-11 Hakutsuru Shuzo Kk 遺伝子発現制御ポリヌクレオチド
GB201107768D0 (en) 2011-05-10 2011-06-22 Univ Manchester Riboswitches

Also Published As

Publication number Publication date
WO2013178674A1 (en) 2013-12-05
US9487767B2 (en) 2016-11-08
BR112014029252A2 (pt) 2017-07-18
EP3327113A3 (en) 2018-08-08
EP2855659A1 (en) 2015-04-08
EP3327113B1 (en) 2021-08-18
US10351861B2 (en) 2019-07-16
US20180298394A1 (en) 2018-10-18
CN104395454B (zh) 2021-11-30
CN104395454A (zh) 2015-03-04
EP3327113A2 (en) 2018-05-30
US20170029830A1 (en) 2017-02-02
US20150175981A1 (en) 2015-06-25
US10351863B2 (en) 2019-07-16
BR112014029252B1 (pt) 2021-10-19
JP6449763B2 (ja) 2019-01-09
BR112014029252B8 (pt) 2022-01-25
JP2015517816A (ja) 2015-06-25

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