DK3321355T3 - Fremgangsmåder og sammensætninger til klinisk afledning af en allogen celle og terapeutiske anvendelser - Google Patents

Fremgangsmåder og sammensætninger til klinisk afledning af en allogen celle og terapeutiske anvendelser Download PDF

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DK3321355T3
DK3321355T3 DK17191442.7T DK17191442T DK3321355T3 DK 3321355 T3 DK3321355 T3 DK 3321355T3 DK 17191442 T DK17191442 T DK 17191442T DK 3321355 T3 DK3321355 T3 DK 3321355T3
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procedures
compositions
therapeutic applications
clinical determination
allogenic cell
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Amit Patel
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Amit Patel
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    • C12N5/0681Cells of the genital tract; Non-germinal cells from gonads
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DK17191442.7T 2011-12-30 2012-12-31 Fremgangsmåder og sammensætninger til klinisk afledning af en allogen celle og terapeutiske anvendelser DK3321355T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161582070P 2011-12-30 2011-12-30
US201261591211P 2012-01-26 2012-01-26
EP12862921.9A EP2798058B1 (en) 2011-12-30 2012-12-31 Methods and compositions for the clinical derivation of an allogenic cell and therapeutic uses

Publications (1)

Publication Number Publication Date
DK3321355T3 true DK3321355T3 (da) 2021-11-08

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ID=48698707

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DK17191442.7T DK3321355T3 (da) 2011-12-30 2012-12-31 Fremgangsmåder og sammensætninger til klinisk afledning af en allogen celle og terapeutiske anvendelser

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Country Link
US (8) US9803176B2 (enExample)
EP (2) EP2798058B1 (enExample)
JP (1) JP6548897B2 (enExample)
CA (2) CA2862661C (enExample)
DK (1) DK3321355T3 (enExample)
ES (2) ES2890126T3 (enExample)
HR (1) HRP20211373T1 (enExample)
HU (1) HUE056817T2 (enExample)
PL (1) PL3321355T3 (enExample)
PT (1) PT3321355T (enExample)
SI (1) SI3321355T1 (enExample)
WO (1) WO2013102219A1 (enExample)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101316602B (zh) 2005-09-27 2015-06-03 组织技术公司 羊膜制品和纯化的组合物及其使用方法
US9526770B2 (en) 2011-04-28 2016-12-27 Tissuetech, Inc. Methods of modulating bone remodeling
EP2717888B1 (en) 2011-06-10 2020-09-09 Tissuetech, Inc. Methods of processing fetal support tissues
US10167448B2 (en) 2013-12-12 2019-01-01 Samsung Life Public Welfare Foundation Pharmaceutical composition for treating cerebrovascular diseases, containing stem cell-derived exosome as active ingredient
EP3120857B1 (en) 2014-03-18 2021-02-17 Samsung Life Public Welfare Foundation Compositions for use in treating inflammatory brain disease comprising stem-cell-derived exosomes as an active ingredient
AU2015264025A1 (en) * 2014-05-21 2016-12-01 Mimedx Group, Inc. Micronized Wharton's jelly
TW201603818A (zh) 2014-06-03 2016-02-01 組織科技股份有限公司 組成物及方法
US20160008410A1 (en) 2014-07-08 2016-01-14 Mimedx Group, Inc. Micronized wharton's jelly
US20160243288A1 (en) 2015-02-23 2016-08-25 Tissuetech, Inc. Apparatuses and methods for treating ophthalmic diseases and disorders
TWI720984B (zh) 2015-05-20 2021-03-11 美商帝聖工業公司 用於防止上皮細胞增生及上皮-間質轉移之組合物及方法
ES2914692T3 (es) 2015-08-12 2022-06-15 Cha Biotech Co Ltd Células madre adhesivas derivadas de cordón umbilical mejoradas, método de preparación para las mismas, y uso de las mismas
US12551509B2 (en) 2015-11-18 2026-02-17 Lucina Patent Holdco, Llc Acellular regenerative products and methods of their manufacture
TW201733600A (zh) 2016-01-29 2017-10-01 帝聖工業公司 胎兒扶持組織物及使用方法
CA3029233A1 (en) * 2016-06-24 2017-12-28 Osiris Therapeutics, Inc. Human tissue derived compositions and uses thereof
WO2018101782A1 (ko) 2016-12-02 2018-06-07 가톨릭대학교 산학협력단 T 세포 자극용 엑소좀 및 이의 약제학적 용도
KR101864234B1 (ko) * 2017-07-04 2018-06-04 인하대학교 산학협력단 음경해면체 유래 엑소좀을 유효성분으로 포함하는, 발기부전 예방, 개선 또는 치료용 조성물
US11285177B2 (en) 2018-01-03 2022-03-29 Globus Medical, Inc. Allografts containing viable cells and methods thereof
CN108239621B (zh) * 2018-01-24 2020-08-18 北京臻溪谷医学研究中心(有限合伙) 一种胎盘亚全能干细胞分离、扩增、冻存、复苏干细胞的方法
EP3911344A4 (en) 2019-01-16 2022-10-19 University of Utah Research Foundation MESENCHYMAL STEM CELL LAYERS FROM HUMAN UMBILICAL CORD AND PROCESS FOR THEIR PRODUCTION
US20210386790A1 (en) * 2019-01-16 2021-12-16 University Of Utah Research Foundation Use of mesenchymal stem cell sheets for preventing uterine scar formation
US20230338428A1 (en) * 2020-09-08 2023-10-26 Amit Patel Allogenic umbilical cord stem cells for treating severe respiratory conditions
US20230057957A1 (en) * 2021-08-23 2023-02-23 Therapeutic Solutions International, Inc. Umbilical cord mesenchymal stem cells for treatment of chronic obstructive pulmonary disease and lung degeneration
US20230295569A1 (en) * 2022-03-15 2023-09-21 Creative Medical Technologies, Inc. Therapeutic regenerative cells
US20230293598A1 (en) * 2022-03-15 2023-09-21 Narkeshyo LLC Prevention of radiation exposure associated pathology by treatment with umbilical cord derived regenerative cells
US20230364148A1 (en) * 2022-05-12 2023-11-16 Therapeutic Solutions International, Inc. Inhibition and reversion of chronic obstructive pulmonary disease (copd) by endothelial cell regeneration
WO2024006911A1 (en) * 2022-06-29 2024-01-04 FUJIFILM Holdings America Corporation Ipsc-derived astrocytes and methods of use thereof

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5486359A (en) 1990-11-16 1996-01-23 Osiris Therapeutics, Inc. Human mesenchymal stem cells
CA2328524A1 (en) 1998-05-29 1999-12-02 Osiris Therapeutics, Inc. Human cd45+ and/or fibroblast + mesenchymal stem cells
US20030161818A1 (en) 2002-02-25 2003-08-28 Kansas State University Research Foundation Cultures, products and methods using stem cells
WO2004072273A1 (en) 2003-02-11 2004-08-26 Davies John E Progenitor cells from wharton's jelly of human umbilical cord
ES2564044T3 (es) 2003-06-27 2016-03-17 DePuy Synthes Products, Inc. Células posparto derivadas de tejido del cordón umbilical y métodos de preparación y uso de las mismas
EP2597149A1 (en) * 2004-08-16 2013-05-29 CellResearch Corporation Pte Ltd Isolation, cultivation and uses of stem/progenitor cells
WO2007106089A1 (en) 2006-03-14 2007-09-20 Spherical Dynamics, Inc. System for and method for psychological assessment
KR101569168B1 (ko) * 2007-02-12 2015-11-13 안트로제네시스 코포레이션 태반 줄기세포를 이용한 염증 질환의 치료
PT103843B (pt) * 2007-10-04 2008-08-12 Medinfar Produtos Farmaceutico Método de isolamento de células precursoras a partir do cordão umbilical humano
MX2011005230A (es) * 2008-11-21 2011-06-16 Anthrogenesis Corp Tratamiento de enfermedades, desordenes o condiciones del pulmon usando celulas de placenta.
CN101748096B (zh) 2008-12-17 2013-03-13 北京汉氏联合生物技术有限公司 亚全能干细胞、其制备方法及其用途
US20120114618A1 (en) 2009-03-26 2012-05-10 The Regents Of The University Of California Mesenchymal Stem Cells Producing Inhibitory RNA for Disease Modification
CN102686722B (zh) * 2009-09-23 2014-11-05 达芬奇生物科技有限责任公司 脐带衬干细胞及其分离和培养方法和材料
CN101890050B (zh) 2010-07-14 2012-07-04 江苏大学 脐带间质干细胞来源膜性囊泡及其应用
EP2540819A1 (en) 2011-06-27 2013-01-02 Rheinisch-Westfälische Technische Hochschule Aachen (RWTH) Method for cultivating cells in platelet-lysate-containing medium
US20210355437A1 (en) 2015-09-02 2021-11-18 Restem Llc Factor rich product from umbilical cord mesenchymal stem cells

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Publication number Publication date
EP3321355A1 (en) 2018-05-16
EP2798058A4 (en) 2015-05-20
US20250346865A1 (en) 2025-11-13
US12441986B2 (en) 2025-10-14
US20220251514A1 (en) 2022-08-11
CA2862661C (en) 2021-05-25
JP6548897B2 (ja) 2019-07-24
US20220251513A1 (en) 2022-08-11
HUE056817T2 (hu) 2022-03-28
EP2798058B1 (en) 2017-10-18
US20220041992A1 (en) 2022-02-10
HRP20211373T1 (hr) 2021-11-26
US20130216505A1 (en) 2013-08-22
CA3113484A1 (en) 2013-07-04
ES2656614T3 (es) 2018-02-27
PL3321355T3 (pl) 2021-12-27
US20190218519A1 (en) 2019-07-18
US20220251515A1 (en) 2022-08-11
ES2890126T3 (es) 2022-01-17
US20260078347A1 (en) 2026-03-19
JP2015503918A (ja) 2015-02-05
US9803176B2 (en) 2017-10-31
SI3321355T1 (sl) 2021-11-30
CA2862661A1 (en) 2013-07-04
EP2798058A1 (en) 2014-11-05
WO2013102219A1 (en) 2013-07-04
PT3321355T (pt) 2021-09-28
EP3321355B1 (en) 2021-08-25

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