US5807A
(en)
|
|
1848-09-26 |
|
Brake fob cabs |
US715A
(en)
|
|
1838-04-28 |
|
Improvement in water-wheels |
US823244A
(en)
|
1906-01-18 |
1906-06-12 |
Emerson Mfg Co |
Wheeled plow.
|
US4179337A
(en)
|
1973-07-20 |
1979-12-18 |
Davis Frank F |
Non-immunogenic polypeptides
|
JPS6023084B2
(ja)
|
1979-07-11 |
1985-06-05 |
味の素株式会社 |
代用血液
|
US4444887A
(en)
|
1979-12-10 |
1984-04-24 |
Sloan-Kettering Institute |
Process for making human antibody producing B-lymphocytes
|
US6872868B1
(en)
|
1981-06-12 |
2005-03-29 |
Ohio University |
Transgenic mammals
|
US4474893A
(en)
|
1981-07-01 |
1984-10-02 |
The University of Texas System Cancer Center |
Recombinant monoclonal antibodies
|
US4714681A
(en)
|
1981-07-01 |
1987-12-22 |
The Board Of Reagents, The University Of Texas System Cancer Center |
Quadroma cells and trioma cells and methods for the production of same
|
US4485045A
(en)
|
1981-07-06 |
1984-11-27 |
Research Corporation |
Synthetic phosphatidyl cholines useful in forming liposomes
|
US4640835A
(en)
|
1981-10-30 |
1987-02-03 |
Nippon Chemiphar Company, Ltd. |
Plasminogen activator derivatives
|
US4716111A
(en)
|
1982-08-11 |
1987-12-29 |
Trustees Of Boston University |
Process for producing human antibodies
|
GB8308235D0
(en)
|
1983-03-25 |
1983-05-05 |
Celltech Ltd |
Polypeptides
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
US4544545A
(en)
|
1983-06-20 |
1985-10-01 |
Trustees University Of Massachusetts |
Liposomes containing modified cholesterol for organ targeting
|
US4496689A
(en)
|
1983-12-27 |
1985-01-29 |
Miles Laboratories, Inc. |
Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer
|
US5807715A
(en)
|
1984-08-27 |
1998-09-15 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin
|
EP0206448B1
(en)
|
1985-06-19 |
1990-11-14 |
Ajinomoto Co., Inc. |
Hemoglobin combined with a poly(alkylene oxide)
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
GB8607679D0
(en)
|
1986-03-27 |
1986-04-30 |
Winter G P |
Recombinant dna product
|
IN164232B
(da)
|
1986-04-11 |
1989-02-04 |
Hoechst India |
|
US4695198A
(en)
|
1986-05-23 |
1987-09-22 |
Chevron Research Company |
Lip-type sealing system for a removable bottom founded structure
|
US4791192A
(en)
|
1986-06-26 |
1988-12-13 |
Takeda Chemical Industries, Ltd. |
Chemically modified protein with polyethyleneglycol
|
DE3751908T2
(de)
*
|
1986-07-07 |
1997-02-06 |
Centocor Inc |
Chimärisches Murine-Mensch-Immunoglobulin, spezifisch für tumorassoziertes 17-1A Antigen
|
US4946778A
(en)
|
1987-09-21 |
1990-08-07 |
Genex Corporation |
Single polypeptide chain binding molecules
|
US5059680A
(en)
|
1986-11-24 |
1991-10-22 |
Centocor, Inc. |
Method of isolating ca 125 antigen
|
US5258498A
(en)
|
1987-05-21 |
1993-11-02 |
Creative Biomolecules, Inc. |
Polypeptide linkers for production of biosynthetic proteins
|
US5091513A
(en)
|
1987-05-21 |
1992-02-25 |
Creative Biomolecules, Inc. |
Biosynthetic antibody binding sites
|
CA1340927C
(en)
|
1987-10-09 |
2000-03-14 |
Peter S. Linsley |
Method for increasing the sensitivity of assays for target ligand
|
IT1212041B
(it)
|
1987-11-02 |
1989-11-08 |
Fidia Farmaceutici |
Gangliosidi esteri interni come agenti terapeutici capaci di eliminare il dolore nelle neuropatie periferiche
|
JPH02486A
(ja)
|
1987-11-13 |
1990-01-05 |
Mect Corp |
遊離n−アセチルノイラミン酸を認識するモノクローナル抗体
|
US4978745A
(en)
|
1987-11-23 |
1990-12-18 |
Centocor, Inc. |
Immunoreactive heterochain antibodies
|
US4975369A
(en)
|
1988-04-21 |
1990-12-04 |
Eli Lilly And Company |
Recombinant and chimeric KS1/4 antibodies directed against a human adenocarcinoma antigen
|
US4925648A
(en)
|
1988-07-29 |
1990-05-15 |
Immunomedics, Inc. |
Detection and treatment of infectious and inflammatory lesions
|
US5601819A
(en)
|
1988-08-11 |
1997-02-11 |
The General Hospital Corporation |
Bispecific antibodies for selective immune regulation and for selective immune cell binding
|
US5223409A
(en)
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
EP1026240A3
(en)
|
1988-09-02 |
2004-04-07 |
Dyax Corp. |
Generation and selection of recombinant varied binding proteins
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
DE3920358A1
(de)
|
1989-06-22 |
1991-01-17 |
Behringwerke Ag |
Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
|
ES2096590T3
(es)
|
1989-06-29 |
1997-03-16 |
Medarex Inc |
Reactivos biespecificos para la terapia del sida.
|
US5413923A
(en)
|
1989-07-25 |
1995-05-09 |
Cell Genesys, Inc. |
Homologous recombination for universal donor cells and chimeric mammalian hosts
|
US5013556A
(en)
|
1989-10-20 |
1991-05-07 |
Liposome Technology, Inc. |
Liposomes with enhanced circulation time
|
US5208020A
(en)
|
1989-10-25 |
1993-05-04 |
Immunogen Inc. |
Cytotoxic agents comprising maytansinoids and their therapeutic use
|
GB8928874D0
(en)
|
1989-12-21 |
1990-02-28 |
Celltech Ltd |
Humanised antibodies
|
US5780225A
(en)
|
1990-01-12 |
1998-07-14 |
Stratagene |
Method for generating libaries of antibody genes comprising amplification of diverse antibody DNAs and methods for using these libraries for the production of diverse antigen combining molecules
|
WO1991010737A1
(en)
|
1990-01-11 |
1991-07-25 |
Molecular Affinities Corporation |
Production of antibodies using gene libraries
|
SG48759A1
(en)
|
1990-01-12 |
2002-07-23 |
Abgenix Inc |
Generation of xenogenic antibodies
|
US6075181A
(en)
|
1990-01-12 |
2000-06-13 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
GB9012995D0
(en)
*
|
1990-06-11 |
1990-08-01 |
Celltech Ltd |
Multivalent antigen-binding proteins
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
US5814318A
(en)
|
1990-08-29 |
1998-09-29 |
Genpharm International Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
US5633425A
(en)
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
ES2108048T3
(es)
|
1990-08-29 |
1997-12-16 |
Genpharm Int |
Produccion y utilizacion de animales inferiores transgenicos capaces de producir anticuerpos heterologos.
|
US5661016A
(en)
|
1990-08-29 |
1997-08-26 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
US5625126A
(en)
|
1990-08-29 |
1997-04-29 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
US6300129B1
(en)
|
1990-08-29 |
2001-10-09 |
Genpharm International |
Transgenic non-human animals for producing heterologous antibodies
|
US5698426A
(en)
|
1990-09-28 |
1997-12-16 |
Ixsys, Incorporated |
Surface expression libraries of heteromeric receptors
|
DE69130709T3
(de)
|
1990-10-05 |
2005-12-22 |
Celldex Therapeutics, Inc. |
Gezielte immunostimulierung mit bispezifischen stoffen
|
AU8727291A
(en)
|
1990-10-29 |
1992-06-11 |
Cetus Oncology Corporation |
Bispecific antibodies, method of production, and uses thereof
|
ES2113940T3
(es)
|
1990-12-03 |
1998-05-16 |
Genentech Inc |
Metodo de enriquecimiento para variantes de proteinas con propiedades de union alteradas.
|
EP0580737B1
(en)
|
1991-04-10 |
2004-06-16 |
The Scripps Research Institute |
Heterodimeric receptor libraries using phagemids
|
IE921342A1
(en)
|
1991-04-26 |
1992-11-04 |
Surface Active Ltd |
Novel antibodies, and methods for their use
|
EP0519596B1
(en)
|
1991-05-17 |
2005-02-23 |
Merck & Co. Inc. |
A method for reducing the immunogenicity of antibody variable domains
|
ES2136092T3
(es)
|
1991-09-23 |
1999-11-16 |
Medical Res Council |
Procedimientos para la produccion de anticuerpos humanizados.
|
EP0617706B1
(en)
|
1991-11-25 |
2001-10-17 |
Enzon, Inc. |
Multivalent antigen-binding proteins
|
US5932448A
(en)
|
1991-11-29 |
1999-08-03 |
Protein Design Labs., Inc. |
Bispecific antibody heterodimers
|
DE69233745D1
(de)
|
1991-12-02 |
2008-10-23 |
Cambridge Antibody Tech |
Herstellung von Autoantikörpern auf Phagenoberflächen ausgehend von Antikörpersegmentbibliotheken
|
DE69332948T2
(de)
|
1992-03-05 |
2003-11-27 |
Univ Texas |
Verwendung von Immunokonjugate zur Diagnose und/oder Therapie der vaskularisierten Tumoren
|
US5733743A
(en)
|
1992-03-24 |
1998-03-31 |
Cambridge Antibody Technology Limited |
Methods for producing members of specific binding pairs
|
CA2076465C
(en)
|
1992-03-25 |
2002-11-26 |
Ravi V. J. Chari |
Cell binding agent conjugates of analogues and derivatives of cc-1065
|
US5639641A
(en)
|
1992-09-09 |
1997-06-17 |
Immunogen Inc. |
Resurfacing of rodent antibodies
|
US5951983A
(en)
|
1993-03-05 |
1999-09-14 |
Universite Catholique De Louvain |
Methods of inhibiting T cell mediated immune responses with humanized LO-CD2A-specific antibodies
|
US20030108548A1
(en)
|
1993-06-01 |
2003-06-12 |
Bluestone Jeffrey A. |
Methods and materials for modulation of the immunosuppressive activity and toxicity of monoclonal antibodies
|
AU696293B2
(en)
|
1993-12-08 |
1998-09-03 |
Genzyme Corporation |
Process for generating specific antibodies
|
EP1231268B1
(en)
|
1994-01-31 |
2005-07-27 |
Trustees Of Boston University |
Polyclonal antibody libraries
|
US5516637A
(en)
|
1994-06-10 |
1996-05-14 |
Dade International Inc. |
Method involving display of protein binding pairs on the surface of bacterial pili and bacteriophage
|
US5786464C1
(en)
|
1994-09-19 |
2012-04-24 |
Gen Hospital Corp |
Overexpression of mammalian and viral proteins
|
US5919652A
(en)
|
1994-11-09 |
1999-07-06 |
The Regents Of The University Of California |
Nucleic acid molecules comprising the prostate specific antigen (PSA) promoter and uses thereof
|
US5710038A
(en)
|
1994-11-25 |
1998-01-20 |
Universite De Montreal |
Primary cultures of normal and tumoral human ovarian epithelium
|
US5811510A
(en)
|
1995-04-14 |
1998-09-22 |
General Hospital Corporation |
Biodegradable polyacetal polymers and methods for their formation and use
|
CA2219361C
(en)
|
1995-04-27 |
2012-02-28 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
AU2466895A
(en)
|
1995-04-28 |
1996-11-18 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
US5733920A
(en)
|
1995-10-31 |
1998-03-31 |
Mitotix, Inc. |
Inhibitors of cyclin dependent kinases
|
JP2978435B2
(ja)
|
1996-01-24 |
1999-11-15 |
チッソ株式会社 |
アクリロキシプロピルシランの製造方法
|
US5849733A
(en)
|
1996-05-10 |
1998-12-15 |
Bristol-Myers Squibb Co. |
2-thio or 2-oxo flavopiridol analogs
|
AU720802B2
(en)
|
1996-07-03 |
2000-06-15 |
Millenium Pharmaceuticals, Inc. |
Detection of cancer by assaying for cancer-specific antigens having linked oligosaccharides which are at least triantennary
|
US6114148C1
(en)
|
1996-09-20 |
2012-05-01 |
Gen Hospital Corp |
High level expression of proteins
|
US5916771A
(en)
|
1996-10-11 |
1999-06-29 |
Abgenix, Inc. |
Production of a multimeric protein by cell fusion method
|
US6348584B1
(en)
|
1996-10-17 |
2002-02-19 |
John Edward Hodgson |
Fibronectin binding protein compounds
|
EP2305027B1
(en)
|
1996-12-03 |
2014-07-02 |
Amgen Fremont Inc. |
Transgenic mammals having human Ig loci including plural VH and Vkappa regions and antibodies produced therefrom
|
ATE200679T1
(de)
|
1997-04-14 |
2001-05-15 |
Micromet Ag |
Neues verfahren zur herstellung von anti-humanen antigenrezeptoren und deren verwendungen
|
US6235883B1
(en)
|
1997-05-05 |
2001-05-22 |
Abgenix, Inc. |
Human monoclonal antibodies to epidermal growth factor receptor
|
EP1958962A3
(en)
|
1997-06-12 |
2013-05-01 |
Novartis International Pharmaceutical Ltd. |
Artificial antibody polypeptides
|
WO1999014353A2
(en)
|
1997-09-19 |
1999-03-25 |
Dana-Farber Cancer Institute, Inc. |
Intrabody-mediated control of immune reactions
|
WO1999037751A1
(en)
|
1998-01-23 |
1999-07-29 |
Imclone Systems Incorporated |
Purified populations of stem cells
|
AU2472400A
(en)
|
1998-10-20 |
2000-05-08 |
City Of Hope |
CD20-specific redirected T cells and their use in cellular immunotherapy of CD20+ malignancies
|
US20030170249A1
(en)
|
1999-02-19 |
2003-09-11 |
Hakomori Sen-Itiroh |
Vaccines directed to cancer-associated carbohydrate antigens
|
US20020012660A1
(en)
|
1999-03-04 |
2002-01-31 |
Alan Colman |
Method of preparing a somatic cells for nuclear transfer
|
GB2344886B
(en)
|
1999-03-10 |
2000-11-01 |
Medical Res Council |
Selection of intracellular immunoglobulins
|
EP1196031A1
(en)
|
1999-06-16 |
2002-04-17 |
Biocrystal Limited |
Vaccine formulations and methods for immunizing an individual against shed antigen-specific b cells
|
EP1642909A3
(en)
|
1999-12-06 |
2006-04-12 |
Agensys, Inc. |
Serpentine transmembrane antigens expressed in human prostate cancers and uses thereof
|
JP2003531820A
(ja)
|
1999-12-17 |
2003-10-28 |
ジーン セラピー システムズ インコーポレーテッド |
細胞内タンパク質送達のためのカチオン性脂質の使用
|
US20030008813A1
(en)
|
1999-12-17 |
2003-01-09 |
Felgner Philip L. |
Intracellular protein delivery compositions and methods of use
|
AU2001253140A1
(en)
|
2000-04-03 |
2001-10-15 |
The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services |
Tumor markers in ovarian cancer
|
IT1317922B1
(it)
|
2000-10-24 |
2003-07-15 |
S I S S A Scuola Internaz Supe |
Metodo per identificare in vivo epitopi intracellulari.
|
US7446179B2
(en)
|
2000-11-07 |
2008-11-04 |
City Of Hope |
CD19-specific chimeric T cell receptor
|
WO2002086096A2
(en)
|
2001-01-23 |
2002-10-31 |
University Of Rochester Medical Center |
Methods of producing or identifying intrabodies in eukaryotic cells
|
US20040047891A1
(en)
|
2001-02-26 |
2004-03-11 |
Sabina Glozman |
Systems devices and methods for intrabody targeted delivery and reloading of therapeutic agents
|
GB0108165D0
(en)
|
2001-03-31 |
2001-05-23 |
Univ Manchester |
Intracellular analysis
|
US20090257994A1
(en)
|
2001-04-30 |
2009-10-15 |
City Of Hope |
Chimeric immunoreceptor useful in treating human cancers
|
US7514537B2
(en)
|
2001-04-30 |
2009-04-07 |
City Of Hope |
Chimeric immunoreceptor useful in treating human gliomas
|
EP1383889B1
(en)
|
2001-04-30 |
2014-11-19 |
RBC Biotechnology, Inc. |
Modified organs and cells for xenotransplantation
|
WO2002088334A1
(en)
|
2001-04-30 |
2002-11-07 |
City Of Hope |
Chimeric immunoreceptor useful in treating human cancers
|
KR100486784B1
(ko)
|
2001-05-22 |
2005-04-29 |
김하형 |
솔비나무로 부터 추출된 렉틴 단백질, 그의 제조방법 및용도
|
WO2002094199A2
(en)
|
2001-05-24 |
2002-11-28 |
Immucom Inc. |
METHOD OF INCREASING ANTI-NeuGc ANTIBODY LEVELS IN BLOOD
|
US6814734B2
(en)
|
2001-06-18 |
2004-11-09 |
Sdgi Holdings, Inc, |
Surgical instrumentation and method for forming a passage in bone having an enlarged cross-sectional portion
|
US20060127893A1
(en)
|
2001-07-19 |
2006-06-15 |
Stefan Ewert |
Modification of human variable domains
|
EP1425694A2
(en)
|
2001-08-03 |
2004-06-09 |
Medical Research Council |
Method of identifying a consensus sequence for intracellular antibodies
|
EP1419176A2
(en)
|
2001-08-17 |
2004-05-19 |
Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts |
Glycoconjugates of sialic acid derivates, methods for their production and use thereof
|
WO2003040185A2
(de)
|
2001-11-09 |
2003-05-15 |
Hexal Biotech Forschungsgmbh |
Anti-n-glykolyl-neuraminsäure-antikörper und ihre verwendung zur bestimmung von glykoproteinen
|
WO2003060071A2
(en)
|
2001-12-21 |
2003-07-24 |
Human Genome Sciences, Inc. |
Albumin fusion proteins
|
IL162721A0
(en)
|
2002-01-22 |
2005-11-20 |
Warner Lambert Co |
2-(Pyridin-2-ylamino)-pyridoÄ2,3-dÜpyrimidin-7-ones
|
GB0201611D0
(en)
|
2002-01-24 |
2002-03-13 |
Grosveld Frank |
Transgenic animal
|
GB0226727D0
(en)
|
2002-11-15 |
2002-12-24 |
Medical Res Council |
Intrabodies
|
GB0226723D0
(en)
|
2002-11-15 |
2002-12-24 |
Medical Res Council |
Antibodies for in vitro use
|
WO2003077945A1
(en)
|
2002-03-14 |
2003-09-25 |
Medical Research Council |
Intracellular antibodies
|
WO2003086276A2
(en)
|
2002-04-05 |
2003-10-23 |
Selective Genetics, Inc. |
Compositions and methods for portal specific gene delivery and treatment of infection
|
EP1506236B1
(en)
|
2002-05-22 |
2013-01-23 |
ESBATech - a Novartis Company LLC |
Immunoglobulin frameworks which demonstrate enhanced stability in the intracellular environment and methods of identifying same
|
US7119200B2
(en)
|
2002-09-04 |
2006-10-10 |
Schering Corporation |
Pyrazolopyrimidines as cyclin dependent kinase inhibitors
|
GB0226729D0
(en)
|
2002-11-15 |
2002-12-24 |
Medical Res Council |
Intracellular antibodies
|
WO2004046188A2
(en)
|
2002-11-15 |
2004-06-03 |
Medical Research Council |
Anti-activated ras antibodies
|
GB0226731D0
(en)
|
2002-11-15 |
2002-12-24 |
Medical Res Council |
Method for generating immunoglobulin genes
|
ITRM20020588A1
(it)
|
2002-11-21 |
2004-05-22 |
Lay Line Genomics Spa |
Metodo per isolare anticorpi intracellulari neutralizzanti di interazioni proteiche.
|
EP1482309A1
(en)
|
2003-05-07 |
2004-12-01 |
Institut Curie |
Means for detecting protein conformation and applications thereof
|
AU2004255934B2
(en)
|
2003-07-11 |
2010-02-25 |
Warner-Lambert Company Llc |
Isethionate salt of a selective CDK4 inhibitor
|
EP2302390B1
(en)
|
2003-07-15 |
2013-06-05 |
The Regents of The University of California |
Methods for detecting and analyzing n-glycolylneuraminic acid (Neu5Gc) specific antibodies in biological materials
|
ITMI20031909A1
(it)
|
2003-10-03 |
2005-04-04 |
Keryos Spa |
Linee cellulari di mammifero modificate per la produzione di glicoproteine ricombinanti.
|
US7884054B2
(en)
|
2003-12-22 |
2011-02-08 |
Amgen Inc. |
Methods for identifying functional antibodies
|
JP2007527539A
(ja)
|
2004-03-05 |
2007-09-27 |
ザ スクリプス リサーチ インスティテュート |
ハイスループットグリカンマイクロアレイ
|
WO2005111082A1
(en)
|
2004-04-30 |
2005-11-24 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Anti-tfr antibody.
|
KR100620554B1
(ko)
|
2004-06-05 |
2006-09-06 |
한국생명공학연구원 |
Tag-72에 대한 인간화 항체
|
CA2571431A1
(en)
|
2004-06-24 |
2006-01-05 |
The Scripps Research Institute |
Arrays with cleavable linkers
|
US7638467B2
(en)
|
2004-08-03 |
2009-12-29 |
Intevep, S.A. |
Reversible gelling system and method using same during well treatments
|
US20060121042A1
(en)
|
2004-10-27 |
2006-06-08 |
Medimmune, Inc. |
Modulation of antibody specificity by tailoring the affinity to cognate antigens
|
WO2006068758A2
(en)
|
2004-11-19 |
2006-06-29 |
The Scripps Research Institute |
Detection, prevention and treatment of breast cancer
|
WO2006116260A2
(en)
|
2005-04-26 |
2006-11-02 |
Medimmune, Inc. |
Modulation of antibody effector function by hinge domain engineering
|
WO2006117910A1
(ja)
|
2005-04-28 |
2006-11-09 |
Mochida Pharmaceutical Co., Ltd. |
抗血小板膜糖蛋白質ⅵモノクローナル抗体
|
US8232448B2
(en)
|
2005-06-08 |
2012-07-31 |
The Regents Of The University Of California |
Transgenic mouse with a homozygous mutation in the CMAH gene
|
ES2390826T3
(es)
|
2005-08-24 |
2012-11-16 |
Immunogen Inc |
Procedimiento para preparar conjugados de fármaco purificados
|
CA2994756C
(en)
|
2005-12-20 |
2020-10-27 |
Sbi Biotech Co., Ltd. |
Anti-ilt7 antibody
|
WO2007079448A2
(en)
|
2006-01-03 |
2007-07-12 |
University Of Georgia Research Foundation, Inc. |
Three component carbohydrate vaccine
|
EP1808442B1
(en)
|
2006-01-13 |
2011-05-11 |
Institut Pasteur |
Enzymatic large-scale synthesis of mucin glyconjugates, and immunogenic applications thereof
|
EP2389948A1
(en)
|
2006-03-23 |
2011-11-30 |
Novartis AG |
Anti-tumor cell antigen antibody therapeutics
|
CA2646807A1
(en)
|
2006-03-31 |
2007-10-18 |
Mochida Pharmaceutical Co., Ltd. |
Novel platelet activation marker and method for determination thereof
|
US20070265170A1
(en)
|
2006-05-15 |
2007-11-15 |
Ola Blixt |
Detection, prevention and treatment of ovarian cancer
|
GB0613209D0
(en)
|
2006-07-03 |
2006-08-09 |
Ucb Sa |
Methods
|
US8440798B2
(en)
|
2006-10-04 |
2013-05-14 |
Københavns Universitet |
Generation of a cancer-specific immune response toward MUC1 and cancer specific MUC1 antibodies
|
US20100143371A1
(en)
|
2006-10-31 |
2010-06-10 |
Zhenping Zhu |
Intrabodies
|
WO2008053486A1
(en)
|
2006-11-02 |
2008-05-08 |
Sylvie Luria |
Methods for screening for therapeutic molecules and use of the molecules therefrom
|
WO2009018438A1
(en)
|
2007-07-31 |
2009-02-05 |
Cornell Research Foundation, Inc. |
Protein discovery using intracellular ribosome display
|
EP2014302A1
(en)
|
2007-07-12 |
2009-01-14 |
Institut Curie |
An antibody specific for the Tn antigen for the treatment of cancer
|
WO2009035494A2
(en)
|
2007-07-30 |
2009-03-19 |
The Scripps Research Institute |
Methods for producing anti-glycan antibodies, vaccines and methods for treating cancer or infectious disease
|
FI20070853A0
(fi)
|
2007-11-09 |
2007-11-09 |
Glykos Finland Oy |
Glykaania sitovat monoklonaaliset vasta-aineet
|
BRPI0819205A2
(pt)
|
2007-11-13 |
2015-06-23 |
Teva Biopharmaceuticals Usa Inc |
Anticorpos humanizados contra tl1a
|
WO2009091826A2
(en)
|
2008-01-14 |
2009-07-23 |
The Board Of Regents Of The University Of Texas System |
Compositions and methods related to a human cd19-specific chimeric antigen receptor (h-car)
|
US8506966B2
(en)
|
2008-02-22 |
2013-08-13 |
Novartis Ag |
Adjuvanted influenza vaccines for pediatric use
|
US20120027813A1
(en)
|
2008-02-22 |
2012-02-02 |
Novartis Vaccines And Diagnostics Srl |
Adjuvanted influenza vaccines for pediatric use
|
US8298773B2
(en)
|
2008-05-02 |
2012-10-30 |
Marko Vuskovic |
Methods, assays and kits for cancer diagnosis and screening utilizing glycan-binding and glycan epitopes
|
US9226934B2
(en)
|
2008-06-02 |
2016-01-05 |
The University Of Tokyo |
Anti-cancer drug
|
US20120039984A1
(en)
|
2008-07-03 |
2012-02-16 |
University Of Georgia Research Foundation, Inc. |
Glycopeptide and uses thereof
|
EP2143735A1
(en)
|
2008-07-10 |
2010-01-13 |
Institut Pasteur |
Variable domains of camelid heavy-chain antibodies directed against glial fibrillary acidic proteins
|
US20100009424A1
(en)
|
2008-07-14 |
2010-01-14 |
Natasha Forde |
Sonoporation systems and methods
|
FI20095418A0
(fi)
|
2009-04-16 |
2009-04-16 |
Suomen Punainen Risti Veripalv |
Kryptinen subpopulaatio
|
PL2331547T3
(pl)
|
2008-08-22 |
2015-01-30 |
Novartis Ag |
Związki pirolopirymidynowe jako inhibitory CDK
|
JP2012501661A
(ja)
|
2008-09-09 |
2012-01-26 |
ザ レジェンツ オブ ザ ユニヴァースティ オブ カリフォルニア |
代謝競合による汚染非ヒトシアル酸の除去
|
US20120045816A1
(en)
|
2008-09-09 |
2012-02-23 |
Sialix, Inc. |
Novel Glycosylated Polypeptides
|
WO2012118928A2
(en)
|
2011-03-01 |
2012-09-07 |
University Of Georgia Research Foundation, Inc. |
Glycoprofiling with multiplexed suspension arrays
|
PA8852901A1
(es)
|
2008-12-22 |
2010-07-27 |
Lilly Co Eli |
Inhibidores de proteina cinasa
|
US20100178292A1
(en)
|
2009-01-12 |
2010-07-15 |
The Board Of Trustees Of The Leland Stanford Junior University |
Cryptic glycan markers and applications thereof
|
US8669085B2
(en)
|
2009-02-05 |
2014-03-11 |
Ut-Battelle, Llc |
Transformation of gram positive bacteria by sonoporation
|
JP2012528240A
(ja)
|
2009-05-28 |
2012-11-12 |
メルサナ セラピューティックス, インコーポレイテッド |
可変速度放出リンカーを含むポリアル−薬物コンジュゲート
|
US8399624B1
(en)
|
2009-06-25 |
2013-03-19 |
Esbatech, An Alcon Biomedical Research Unit Llc |
Acceptor framework for CDR grafting
|
AU2010268690B2
(en)
|
2009-07-03 |
2011-11-10 |
Avipep Pty Ltd |
Immuno-conjugates and methods for producing them
|
EP2275442A1
(en)
|
2009-07-06 |
2011-01-19 |
Ludwig-Maximilians-Universität München |
Detection and vizualization of the cell cycle in living cells
|
WO2011016238A1
(en)
|
2009-08-06 |
2011-02-10 |
Immunas Pharma, Inc. |
Antibodies that specifically bind to a beta oligomers and use thereof
|
EP2287202A1
(en)
*
|
2009-08-07 |
2011-02-23 |
Dublin City University |
Anti-sialic acid antibody molecules
|
AU2010301042B2
(en)
|
2009-10-01 |
2014-03-20 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anti-vascular endothelial growth factor receptor-2 chimeric antigen receptors and use of same for the treatment of cancer
|
BR112012012983A2
(pt)
|
2009-12-04 |
2020-09-15 |
Genentech Inc |
método para sintetizar um anticorpo multiespecífico, método para sintetizar um painel de anticorpos multiespecíficos, método para sintetizar um análogo de anticorpo, método para sintetizar um painel de análogos de anticorpo e composições
|
EP2524233A4
(en)
|
2010-01-15 |
2013-07-31 |
Univ California |
COMPOSITIONS AND METHODS FOR DETECTION OF CANCER
|
EP2347769A1
(en)
|
2010-01-20 |
2011-07-27 |
Glycotope GmbH |
Cancer stem cell markers and uses thereof
|
EP2565268A4
(en)
|
2010-04-28 |
2013-10-09 |
Shionogi & Co |
NEW MUC1 ANTIBODY
|
WO2011139973A2
(en)
|
2010-05-03 |
2011-11-10 |
Abbott Laboratories |
Methods of inhibiting fibrosis using anti-pai-1 antibodies
|
CA2800911A1
(en)
|
2010-06-11 |
2011-12-15 |
University Of Georgia Research Foundation, Inc. |
Immunogenic vaccine
|
CA2805222A1
(en)
|
2010-07-13 |
2012-01-19 |
Ultragenyx Pharmaceutical Inc. |
Methods and formulations for treating sialic acid deficiencies
|
EP2407487A1
(en)
|
2010-07-14 |
2012-01-18 |
F-Star Biotechnologische Forschungs - und Entwicklungsges. M.B.H. |
Multispecific modular antibody
|
JP6157352B2
(ja)
|
2010-10-08 |
2017-07-05 |
シティ・オブ・ホープCity of Hope |
メディトープ(Meditope)のためのモノクローナル抗体フレームワーク結合インターフェース、メディトープ送達系、およびその使用法
|
AR083797A1
(es)
|
2010-11-10 |
2013-03-20 |
Novartis Ag |
Succinato de dimetil-amida del acido 7-ciclopentil-2-(5-piperazin-1-il-piridin-2-il-amino)-7h-pirrolo-[2,3-d]pirimidin-6-carboxilico, proceso para prepararla, intermediarios de dicha sintesis y proceso de preparacion de los mismos
|
SG10201510092QA
(en)
*
|
2010-12-09 |
2016-01-28 |
Univ Pennsylvania |
Use of chimeric antigen receptor-modified t cells to treat cancer
|
EP2661492B1
(en)
|
2011-01-06 |
2017-10-04 |
The Johns Hopkins University |
Method of production of recombinant glycoproteins with increased circulatory half-life in mammalian cells
|
WO2012106465A2
(en)
|
2011-02-01 |
2012-08-09 |
Hibm Research Group, Inc. |
Methods and compositions for increasing sialic acid production and treating sialic related disease conditions
|
US9487583B2
(en)
|
2011-03-30 |
2016-11-08 |
National University Corporation University Of Toyama |
Method for selecting plasma cells or plasmablasts, method for producing target antigen specific antibodies, and novel monoclonal antibodies
|
AU2012267447B2
(en)
|
2011-06-10 |
2016-10-20 |
Mersana Therapeutics, Inc. |
Protein-polymer-drug conjugates
|
JP6244301B2
(ja)
|
2011-08-18 |
2017-12-06 |
アフィニティ バイオサイエンス ピーティーワイ リミテッド |
可溶性ポリペプチド
|
WO2013033420A1
(en)
|
2011-08-30 |
2013-03-07 |
Whitehead Institute For Biomedical Research |
Methods of downregulating translocated oncogene expression using bromodomain inhibitors
|
SG11201400527XA
(en)
|
2011-09-16 |
2014-04-28 |
Univ Pennsylvania |
Rna engineered t cells for the treatment of cancer
|
SG11201401411TA
(en)
|
2011-10-10 |
2014-08-28 |
Hope City |
Meditopes and meditope-binding antibodies and uses thereof
|
US10391126B2
(en)
|
2011-11-18 |
2019-08-27 |
Board Of Regents, The University Of Texas System |
CAR+ T cells genetically modified to eliminate expression of T-cell receptor and/or HLA
|
EA201400709A1
(ru)
|
2011-12-19 |
2016-08-31 |
Синиммун Гмбх |
Молекула биспецифического антитела
|
AU2013203422A1
(en)
|
2012-01-06 |
2013-07-18 |
Bioalliance C.V. |
Anti-transferrin receptor antibodies and methods using same
|
EP2817318A4
(en)
|
2012-02-22 |
2016-04-27 |
Univ Pennsylvania |
COMPOSITIONS AND METHOD FOR GENERATING A PERSISTENT POPULATION OF T CELLS FOR CANCER TREATMENT
|
JP2015512246A
(ja)
|
2012-03-15 |
2015-04-27 |
パーミオン バイオロジクス, インコーポレイテッド |
細胞内抗体および抗体様モイエティの送達のための細胞透過組成物ならびに使用方法
|
WO2013151649A1
(en)
*
|
2012-04-04 |
2013-10-10 |
Sialix Inc |
Glycan-interacting compounds
|
PT2850106T
(pt)
|
2012-05-18 |
2022-07-18 |
Aptevo Res & Development Llc |
Imunofusão biespecífica (bif) de scfv de ligação a cd123 e cd3
|
AU2013302696B9
(en)
|
2012-08-14 |
2018-08-09 |
Ibc Pharmaceuticals, Inc. |
T-cell redirecting bispecific antibodies for treatment of disease
|
CN104769113B
(zh)
|
2012-08-22 |
2017-10-31 |
牧岩生命科学研究所 |
超稳定免疫球蛋白可变结构域的筛选和改造方法及其应用
|
WO2014039513A2
(en)
|
2012-09-04 |
2014-03-13 |
The Trustees Of The University Of Pennsylvania |
Inhibition of diacylglycerol kinase to augment adoptive t cell transfer
|
WO2014055771A1
(en)
|
2012-10-05 |
2014-04-10 |
The Trustees Of The University Of Pennsylvania |
Human alpha-folate receptor chimeric antigen receptor
|
AU2013341353B2
(en)
|
2012-11-06 |
2017-03-16 |
Children's Medical Center Corporation |
Compositions and methods for modulating cell signaling
|
EP2928503B1
(en)
|
2012-12-10 |
2019-02-20 |
Mersana Therapeutics, Inc. |
Conjugates of auristatin compounds
|
CN105102480B
(zh)
|
2012-12-24 |
2019-04-16 |
艾伯维公司 |
催乳素受体结合蛋白及其用途
|
EP2752487A1
(en)
|
2013-01-03 |
2014-07-09 |
Sanofi |
Intracellular phenotypic screening
|
US20160022829A1
(en)
|
2013-03-14 |
2016-01-28 |
Mersana Therapeutics, Inc. |
Tubulysin compounds and conjugates thereof
|
KR20150130349A
(ko)
|
2013-03-15 |
2015-11-23 |
메르크 파텐트 게엠베하 |
4가 이중특이적 항체
|
RU2714733C2
(ru)
|
2013-03-15 |
2020-02-19 |
Мемориал Слоан-Кеттеринг Кэнсер Сентер |
Технологии мультимеризации
|
ES2800602T3
(es)
|
2013-07-23 |
2021-01-04 |
Ohio State Innovation Foundation |
Procedimientos y composiciones relacionados con los fragmentos de anticuerpos monocatenarios que se unen a la glucoproteína 72 asociada a tumor (TAG-72)
|
WO2015048748A1
(en)
|
2013-09-30 |
2015-04-02 |
Board Of Regents, The University Of Texas System |
Myeloid-derived suppressor cell-specific peptides for diagnostic and therapeutic use
|
EP3054974A4
(en)
|
2013-10-10 |
2017-06-14 |
Siamab Therapeutics, Inc. |
Glycan-interacting compounds and methods of use
|
ES2797050T3
(es)
|
2014-03-04 |
2020-12-01 |
Sigma Aldrich Co Llc |
Células virales resistentes y sus usos
|
GB201406767D0
(en)
|
2014-04-15 |
2014-05-28 |
Cancer Rec Tech Ltd |
Humanized anti-Tn-MUC1 antibodies anf their conjugates
|
IL249092B
(en)
|
2014-05-28 |
2022-07-01 |
Agenus Inc |
Anti-gitr antibodies and methods of using them
|
TWI695011B
(zh)
|
2014-06-18 |
2020-06-01 |
美商梅爾莎納醫療公司 |
抗her2表位之單株抗體及其使用之方法
|
EP3185884A4
(en)
|
2014-08-27 |
2018-04-11 |
Oncomed Pharmaceuticals, Inc. |
Combination therapy for treatment of cancer
|
US20170305950A1
(en)
|
2014-10-10 |
2017-10-26 |
Siamab Therapeutics, Inc. |
Glycan analysis and profiling
|
US20180280504A1
(en)
|
2014-10-10 |
2018-10-04 |
Siamab Therapeutics, Inc. |
Glycan-interacting compounds and methods of use
|
CA2967595A1
(en)
|
2014-11-12 |
2016-05-19 |
Siamab Therapeutics, Inc. |
Glycan-interacting compounds and methods of use
|
US9879087B2
(en)
*
|
2014-11-12 |
2018-01-30 |
Siamab Therapeutics, Inc. |
Glycan-interacting compounds and methods of use
|
WO2016090034A2
(en)
|
2014-12-03 |
2016-06-09 |
Novartis Ag |
Methods for b cell preconditioning in car therapy
|
JP6968698B2
(ja)
|
2015-03-17 |
2021-11-24 |
メモリアル スローン ケタリング キャンサー センター |
抗muc16抗体及びその使用
|
EP3091032A1
(en)
|
2015-05-08 |
2016-11-09 |
Miltenyi Biotec GmbH |
Humanized antibody or fragment thereof specific for cd3
|
US20200041517A1
(en)
|
2015-06-12 |
2020-02-06 |
Seattle Genetics, Inc. |
Compositions and methods for targeting cancer stem cells
|
CA3002097A1
(en)
|
2015-11-12 |
2017-05-18 |
Siamab Therapeutics, Inc. |
Glycan-interacting compounds and methods of use
|
US20190031780A1
(en)
|
2016-01-27 |
2019-01-31 |
Siamab Therapeutics, Inc. |
Compositions and methods for targeting cancer stem cells
|
US11401330B2
(en)
|
2016-11-17 |
2022-08-02 |
Seagen Inc. |
Glycan-interacting compounds and methods of use
|
WO2018094144A1
(en)
|
2016-11-17 |
2018-05-24 |
Siamab Therapeutics, Inc. |
Compositions and methods for treating cancer
|
BR112019018043A2
(pt)
|
2017-03-03 |
2020-04-07 |
Seattle Genetics Inc |
método de tratamento de câncer, e, conjugado de anticorpo-fármaco
|