ATE537189T1 - Anti-tfr-antikörper - Google Patents
Anti-tfr-antikörperInfo
- Publication number
- ATE537189T1 ATE537189T1 AT04762981T AT04762981T ATE537189T1 AT E537189 T1 ATE537189 T1 AT E537189T1 AT 04762981 T AT04762981 T AT 04762981T AT 04762981 T AT04762981 T AT 04762981T AT E537189 T1 ATE537189 T1 AT E537189T1
- Authority
- AT
- Austria
- Prior art keywords
- tfr antibodies
- antibody
- tfr
- antibodies
- relates
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2881—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD71
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/EP2004/005744 WO2005111082A1 (en) | 2004-04-30 | 2004-04-30 | Anti-tfr antibody. |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE537189T1 true ATE537189T1 (de) | 2011-12-15 |
Family
ID=34958155
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT04762981T ATE537189T1 (de) | 2004-04-30 | 2004-04-30 | Anti-tfr-antikörper |
Country Status (8)
Country | Link |
---|---|
US (1) | US7976841B2 (de) |
EP (1) | EP1740616B1 (de) |
AT (1) | ATE537189T1 (de) |
DK (1) | DK1740616T3 (de) |
ES (1) | ES2379526T3 (de) |
PL (1) | PL1740616T3 (de) |
PT (1) | PT1740616E (de) |
WO (1) | WO2005111082A1 (de) |
Families Citing this family (55)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20110014607A (ko) | 2008-04-29 | 2011-02-11 | 아보트 러보러터리즈 | 이원 가변 도메인 면역글로불린 및 이의 용도 |
NZ589434A (en) | 2008-06-03 | 2012-11-30 | Abbott Lab | Dual variable domain immunoglobulins and uses thereof |
EP2403531A4 (de) | 2009-03-05 | 2013-02-27 | Abbott Lab | Il-17-bindende proteine |
WO2011007208A1 (en) * | 2009-07-16 | 2011-01-20 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Compounds and methods for the treatment of cancer |
KR101539684B1 (ko) | 2010-05-14 | 2015-07-27 | 애브비 인코포레이티드 | Il-1 결합 단백질 |
UY33492A (es) | 2010-07-09 | 2012-01-31 | Abbott Lab | Inmunoglobulinas con dominio variable dual y usos de las mismas |
AU2011285852B2 (en) | 2010-08-03 | 2014-12-11 | Abbvie Inc. | Dual variable domain immunoglobulins and uses thereof |
TWI689314B (zh) | 2010-11-30 | 2020-04-01 | 建南德克公司 | 低親和力血腦障壁受體抗體及其用途 |
CA2821976A1 (en) | 2010-12-21 | 2012-09-13 | Abbvie Inc. | Il-1 -alpha and -beta bispecific dual variable domain immunoglobulins and their use |
RU2013150331A (ru) * | 2011-04-20 | 2015-05-27 | Рош Гликарт Аг | СПОСОБ И УСТРОЙСТВА ДЛЯ рН-ЗАВИСИМОГО ПРОХОЖДЕНИЯ ГЕМАТОЭНЦЕФАЛИЧЕСКОГО БАРЬЕРА |
CN103534272B (zh) | 2011-05-09 | 2016-05-11 | 株式会社英仙蛋白质科学 | 能够特异性识别转铁蛋白受体的抗体 |
WO2012162561A2 (en) | 2011-05-24 | 2012-11-29 | Zyngenia, Inc. | Multivalent and monovalent multispecific complexes and their uses |
WO2019071023A1 (en) | 2017-10-04 | 2019-04-11 | Yale University | COMPOSITIONS AND METHODS FOR MAKING POLYPEPTIDES CONTAINING SELENOCYSTEINE |
TWI450727B (zh) | 2011-12-29 | 2014-09-01 | Ind Tech Res Inst | 抗人類輸鐵蛋白受體的單域抗體與其應用 |
EP3505534A1 (de) | 2012-06-08 | 2019-07-03 | Sutro Biopharma, Inc. | Antikörper mit nichtnatürlichen stellenspezifischen aminosäureresten, verfahren zu deren herstellung und verfahren zu deren verwendung |
AR091755A1 (es) | 2012-07-12 | 2015-02-25 | Abbvie Inc | Proteinas de union a il-1 |
EP2880059A1 (de) | 2012-08-02 | 2015-06-10 | Institut National de la Santé et de la Recherche Médicale (INSERM) | Verwendung eines transferrin-rezeptorantagonisten zur behandlung von thalassämie |
BR112015004022B1 (pt) | 2012-08-31 | 2023-04-25 | Sutro Biopharma, Inc | Aminoácidos modificados compreendendo um grupo azido |
ES2689782T3 (es) | 2012-11-08 | 2018-11-15 | University Of Miyazaki | Anticuerpo capaz de reconocer específicamente un receptor de transferrina |
WO2014144600A2 (en) | 2013-03-15 | 2014-09-18 | Viktor Roschke | Multivalent and monovalent multispecific complexes and their uses |
EP2971047A4 (de) * | 2013-03-15 | 2016-11-30 | Alper Biotech Llc | Monoklonale antikörper gegen transferrin und transferrin-rezeptorantigene sowie verwendungen davon |
TWI573805B (zh) | 2013-05-20 | 2017-03-11 | 建南德克公司 | 抗轉鐵蛋白受體抗體及其使用方法 |
US9499628B2 (en) * | 2013-06-14 | 2016-11-22 | Children's Hospital Medical Center | Method of boosting the immune response in neonates |
US9764039B2 (en) | 2013-07-10 | 2017-09-19 | Sutro Biopharma, Inc. | Antibodies comprising multiple site-specific non-natural amino acid residues, methods of their preparation and methods of their use |
WO2015054658A1 (en) | 2013-10-11 | 2015-04-16 | Sutro Biopharma, Inc. | Modified amino acids comprising tetrazine functional groups, methods of preparation, and methods of their use |
JP6951973B2 (ja) | 2014-11-12 | 2021-10-20 | シージェン インコーポレイテッド | グリカン相互作用化合物及び使用方法 |
CN107250158B (zh) | 2014-11-19 | 2022-03-25 | 基因泰克公司 | 抗转铁蛋白受体/抗bace1多特异性抗体和使用方法 |
EP3221362B1 (de) | 2014-11-19 | 2019-07-24 | F.Hoffmann-La Roche Ag | Anti-transferrin-rezeptor-antikörper und verfahren zur verwendung |
PL3292149T3 (pl) | 2015-05-04 | 2022-03-21 | Cytomx Therapeutics, Inc. | Aktywowalne przeciwciała anty-cd71 i sposoby ich stosowania |
JP6858185B2 (ja) * | 2015-07-22 | 2021-04-14 | イナサリス | 増殖性および炎症性疾患の処置における抗TfR抗体およびその使用 |
WO2017083582A1 (en) | 2015-11-12 | 2017-05-18 | Siamab Therapeutics, Inc. | Glycan-interacting compounds and methods of use |
WO2017218698A1 (en) | 2016-06-15 | 2017-12-21 | Sutro Biopharma, Inc. | Antibodies with engineered ch2 domains, compositions thereof and methods of using the same |
WO2018094143A1 (en) | 2016-11-17 | 2018-05-24 | Siamab Therapeutics, Inc. | Glycan-interacting compounds and methods of use |
AU2018226824A1 (en) | 2017-03-03 | 2019-09-19 | Seagen Inc. | Glycan-interacting compounds and methods of use |
WO2018165619A1 (en) | 2017-03-09 | 2018-09-13 | Cytomx Therapeutics, Inc. | Cd147 antibodies, activatable cd147 antibodies, and methods of making and use thereof |
WO2019173771A1 (en) | 2018-03-09 | 2019-09-12 | Cytomx Therapeutics, Inc. | Activatable cd147 antibodies and methods of making and use thereof |
EP3552631A1 (de) | 2018-04-10 | 2019-10-16 | Inatherys | Antikörper-arzneimittel-konjugate und deren verwendungen zur behandlung von krebs |
US20210186880A1 (en) | 2018-08-03 | 2021-06-24 | Brown University | Oral formulations with increased uptake |
CN113164594A (zh) | 2018-11-20 | 2021-07-23 | 株式会社英仙蛋白质科学 | 向细胞内摄入铁的抑制剂 |
CN114269749A (zh) | 2019-06-10 | 2022-04-01 | 苏特罗生物制药公司 | 5H-吡咯并[3,2-d]嘧啶-2,4-二氨基化合物及其抗体偶联物 |
US20220259202A1 (en) | 2019-06-17 | 2022-08-18 | Sutro Biopharma, Inc. | 1-(4-(aminomethyl)benzyl)-2-butyl-2h-pyrazolo[3,4-c]quinolin-4-amine derivatives and related compounds as toll-like receptor (tlr) 7/8 agonists, as well as antibody drug conjugates thereof for use in cancer therapy and diagnosis |
WO2021045184A1 (ja) | 2019-09-04 | 2021-03-11 | 株式会社ペルセウスプロテオミクス | 多血症治療薬 |
CN114650844A (zh) | 2019-09-23 | 2022-06-21 | 西托姆克斯治疗公司 | 抗cd47抗体、可活化抗cd47抗体及其使用方法 |
WO2021107082A1 (ja) | 2019-11-27 | 2021-06-03 | 株式会社ペルセウスプロテオミクス | 癌性腹膜炎の治療薬 |
WO2021178597A1 (en) | 2020-03-03 | 2021-09-10 | Sutro Biopharma, Inc. | Antibodies comprising site-specific glutamine tags, methods of their preparation and methods of their use |
EP4143234A1 (de) | 2020-04-26 | 2023-03-08 | Biocytogen Pharmaceuticals (Beijing) Co., Ltd. | Modifizierte immunglobuline |
WO2022000167A1 (zh) * | 2020-06-29 | 2022-01-06 | 中国科学院昆明动物研究所 | 转铁蛋白、转铁蛋白受体及其抗体在制备抗SARS-CoV-2病毒的药物中的应用 |
EP4227686A1 (de) | 2020-10-08 | 2023-08-16 | National University Corporation Tokai National Higher Education and Research System | Verfahren zur bestimmung der empfindlichkeit oder der medizinischen wirkung eines anti-transferrin-rezeptorantikörpers |
WO2022103983A2 (en) | 2020-11-11 | 2022-05-19 | Sutro Biopharma, Inc. | Fluorenylmethyloxycarbonyl and fluorenylmethylaminocarbonyl compounds, protein conjugates thereof, and methods for their use |
WO2023010060A2 (en) | 2021-07-27 | 2023-02-02 | Novab, Inc. | Engineered vlrb antibodies with immune effector functions |
CN117836003A (zh) | 2021-08-26 | 2024-04-05 | 株式会社英仙蛋白质科学 | Ros(活性氧类)产生增强剂 |
TW202328187A (zh) | 2021-09-01 | 2023-07-16 | 美商百健Ma公司 | 抗運鐵蛋白受體抗體及其用途 |
WO2023164487A1 (en) | 2022-02-22 | 2023-08-31 | Brown University | Compositions and methods to achieve systemic uptake of particles following oral or mucosal administration |
US20240091365A1 (en) | 2022-06-27 | 2024-03-21 | Sutro Biopharma, Inc. | Beta-glucuronide linker-payloads, protein conjugates thereof, and methods thereof |
WO2024015229A1 (en) | 2022-07-15 | 2024-01-18 | Sutro Biopharma, Inc. | Protease/enzyme cleavable linker-payloads and protein conjugates |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5530101A (en) * | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
ATE154245T1 (de) | 1990-03-27 | 1997-06-15 | Salk Inst For Biological Studi | Verfahren zur zellwachstumshinderung und dazu nützliche verbindungen |
CN1119726C (zh) * | 1997-12-19 | 2003-08-27 | 阿苏拉布股份有限公司 | 包括两个叠置显示装置的显示组件及含该显示组件的时计 |
US6542146B1 (en) * | 1999-05-27 | 2003-04-01 | Lear Corporation | Transparent electroluminescent display with mechanical gauge |
-
2004
- 2004-04-30 WO PCT/EP2004/005744 patent/WO2005111082A1/en active Application Filing
- 2004-04-30 PT PT04762981T patent/PT1740616E/pt unknown
- 2004-04-30 ES ES04762981T patent/ES2379526T3/es not_active Expired - Lifetime
- 2004-04-30 US US11/579,088 patent/US7976841B2/en active Active
- 2004-04-30 PL PL04762981T patent/PL1740616T3/pl unknown
- 2004-04-30 EP EP04762981A patent/EP1740616B1/de not_active Expired - Lifetime
- 2004-04-30 DK DK04762981.1T patent/DK1740616T3/da active
- 2004-04-30 AT AT04762981T patent/ATE537189T1/de active
Also Published As
Publication number | Publication date |
---|---|
ES2379526T3 (es) | 2012-04-27 |
DK1740616T3 (da) | 2012-03-26 |
WO2005111082A1 (en) | 2005-11-24 |
PT1740616E (pt) | 2012-03-23 |
EP1740616A1 (de) | 2007-01-10 |
US7976841B2 (en) | 2011-07-12 |
US20080193453A1 (en) | 2008-08-14 |
PL1740616T3 (pl) | 2012-06-29 |
EP1740616B1 (de) | 2011-12-14 |
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