DK3178944T3 - Fremgangsmåde til anvendelse af genekspression til bestemmelse af sandsynligheden for et klinisk resultat for nyrecancer - Google Patents

Fremgangsmåde til anvendelse af genekspression til bestemmelse af sandsynligheden for et klinisk resultat for nyrecancer Download PDF

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DK3178944T3
DK3178944T3 DK17153152.8T DK17153152T DK3178944T3 DK 3178944 T3 DK3178944 T3 DK 3178944T3 DK 17153152 T DK17153152 T DK 17153152T DK 3178944 T3 DK3178944 T3 DK 3178944T3
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likelihood
risk
gene expression
clinical result
applying gene
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DK17153152.8T
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Steven Shak
Audrey Goddard
Dejan Knezevic
Tara Maddala
Frederick L Baehner
Wayne Cowens
Joffre B Baker
Michael C Kiefer
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Genomic Health Inc
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57438—Specifically defined cancers of liver, pancreas or kidney
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N7/00—Computing arrangements based on specific mathematical models
    • G06N7/01—Probabilistic graphical models, e.g. probabilistic networks
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/10—Gene or protein expression profiling; Expression-ratio estimation or normalisation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B99/00—Subject matter not provided for in other groups of this subclass
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • Engineering & Computer Science (AREA)
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  • Chemical & Material Sciences (AREA)
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  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
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  • Genetics & Genomics (AREA)
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  • Urology & Nephrology (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Evolutionary Biology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
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  • General Engineering & Computer Science (AREA)
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  • Gastroenterology & Hepatology (AREA)
  • Food Science & Technology (AREA)
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DK17153152.8T 2010-01-11 2011-01-07 Fremgangsmåde til anvendelse af genekspression til bestemmelse af sandsynligheden for et klinisk resultat for nyrecancer DK3178944T3 (da)

Applications Claiming Priority (3)

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US29403810P 2010-01-11 2010-01-11
US34623010P 2010-05-19 2010-05-19
EP15203193.6A EP3029155A3 (en) 2010-01-11 2011-01-07 Method to use gene expression to determine likelihood of clinical outcome of renal cancer

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DK17153152.8T DK3178944T3 (da) 2010-01-11 2011-01-07 Fremgangsmåde til anvendelse af genekspression til bestemmelse af sandsynligheden for et klinisk resultat for nyrecancer

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US (4) US9551034B2 (enExample)
EP (5) EP3029155A3 (enExample)
JP (5) JP6286124B2 (enExample)
AU (1) AU2011203977B2 (enExample)
CA (3) CA3256492A1 (enExample)
DK (1) DK3178944T3 (enExample)
ES (2) ES2741379T3 (enExample)
IL (6) IL219978A (enExample)
MX (3) MX375138B (enExample)
NZ (4) NZ600268A (enExample)
SG (1) SG181806A1 (enExample)
WO (1) WO2011085263A2 (enExample)

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EP3561078A1 (en) 2019-10-30
EP2524055A4 (en) 2013-06-05
US9551034B2 (en) 2017-01-24
JP6286124B2 (ja) 2018-02-28
EP3831964A2 (en) 2021-06-09
JP2016174600A (ja) 2016-10-06
EP2524055A2 (en) 2012-11-21
IL251635A0 (en) 2017-06-29
JP2019162150A (ja) 2019-09-26
AU2011203977B2 (en) 2015-02-05
JP7307602B2 (ja) 2023-07-12
NZ617003A (en) 2015-04-24
WO2011085263A2 (en) 2011-07-14
EP3029155A3 (en) 2016-08-31
CA2783858C (en) 2021-09-14
US11776664B2 (en) 2023-10-03
CA2783858A1 (en) 2011-07-14
US20170121780A1 (en) 2017-05-04
IL219978A (en) 2017-04-30
IL256335B (en) 2018-12-31
NZ719474A (en) 2018-07-27
EP3029155A2 (en) 2016-06-08
MX2012007882A (es) 2012-08-03
EP3831964A3 (en) 2021-10-20
IL262100A (en) 2018-11-29
IL270151B (en) 2021-03-25
CA3128103A1 (en) 2011-07-14
IL280689B (en) 2022-01-01
WO2011085263A3 (en) 2012-01-12
JP7385630B2 (ja) 2023-11-22
IL219978A0 (en) 2012-07-31
US20110171633A1 (en) 2011-07-14
US20220051755A9 (en) 2022-02-17
JP6546214B2 (ja) 2019-07-17
EP3178944A3 (en) 2017-09-13
JP2017148059A (ja) 2017-08-31
EP3831964B1 (en) 2025-04-16
IL280689A (en) 2021-03-25
ES3027507T3 (en) 2025-06-16
US12412642B2 (en) 2025-09-09
MX2020009704A (es) 2020-10-07
IL262100B (en) 2019-11-28
CA3128103C (en) 2025-11-18
IL251635B (en) 2018-04-30
SG181806A1 (en) 2012-07-30
JP2021177761A (ja) 2021-11-18
ES2741379T3 (es) 2020-02-10
JP2013516195A (ja) 2013-05-13
MX341866B (es) 2016-09-06
NZ600268A (en) 2014-08-29
CA3256492A1 (en) 2025-11-29
NZ705645A (en) 2016-05-27
US10892038B2 (en) 2021-01-12
MX375138B (es) 2025-03-06
AU2011203977A1 (en) 2012-06-21
US20210166790A1 (en) 2021-06-03
US20240096451A1 (en) 2024-03-21
EP3178944A2 (en) 2017-06-14
EP3178944B1 (en) 2019-05-15

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