DK3083590T3 - Ikke-steroide antiandrogener og selektive androgenreceptormodulatorer med en pyridyldel - Google Patents

Ikke-steroide antiandrogener og selektive androgenreceptormodulatorer med en pyridyldel Download PDF

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Publication number
DK3083590T3
DK3083590T3 DK14872056.8T DK14872056T DK3083590T3 DK 3083590 T3 DK3083590 T3 DK 3083590T3 DK 14872056 T DK14872056 T DK 14872056T DK 3083590 T3 DK3083590 T3 DK 3083590T3
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androgen receptor
receptor modulators
selective androgen
pyridyl moiety
steroidal antiandrogens
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DK14872056.8T
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Danish (da)
English (en)
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Fernand Labrie
Shankar Mohan Singh
Richard Labrecque
Liviu Constantin Ciobanu
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Endorecherche Inc
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
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    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
    • A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
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DK14872056.8T 2013-12-19 2014-12-16 Ikke-steroide antiandrogener og selektive androgenreceptormodulatorer med en pyridyldel DK3083590T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361918133P 2013-12-19 2013-12-19
US14/567,970 US9682960B2 (en) 2013-12-19 2014-12-11 Non-steroidal antiandrogens and selective androgen receptor modulators with a pyridyl moiety
PCT/CA2014/000894 WO2015089634A1 (en) 2013-12-19 2014-12-16 Non-steroidal antiandrogens and selective androgen receptor modulators with a pyridyl moiety

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DK3083590T3 true DK3083590T3 (da) 2020-03-09

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DK14872056.8T DK3083590T3 (da) 2013-12-19 2014-12-16 Ikke-steroide antiandrogener og selektive androgenreceptormodulatorer med en pyridyldel

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US (1) US9682960B2 (enExample)
EP (1) EP3083590B1 (enExample)
JP (2) JP6698022B2 (enExample)
CN (1) CN105873917B (enExample)
AR (1) AR098887A1 (enExample)
AU (1) AU2014366802B2 (enExample)
BR (1) BR112016014326B1 (enExample)
CA (1) CA2933693C (enExample)
DK (1) DK3083590T3 (enExample)
EA (1) EA032467B1 (enExample)
ES (1) ES2771748T3 (enExample)
HU (1) HUE047975T2 (enExample)
TW (1) TWI639585B (enExample)
WO (1) WO2015089634A1 (enExample)

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US9682960B2 (en) * 2013-12-19 2017-06-20 Endorecherche, Inc. Non-steroidal antiandrogens and selective androgen receptor modulators with a pyridyl moiety
TW201630899A (zh) 2015-01-09 2016-09-01 必治妥美雅史谷比公司 作為ｒｏｃｋ抑制劑的環狀脲類
TWI726969B (zh) 2016-01-11 2021-05-11 比利時商健生藥品公司 用作雄性激素受體拮抗劑之經取代之硫尿囊素衍生物
WO2018005533A1 (en) 2016-07-01 2018-01-04 G1 Therapeutics, Inc. Antiproliferative pyrimidine-based compounds
WO2019226213A2 (en) 2018-03-08 2019-11-28 Incyte Corporation AMINOPYRAZINE DIOL COMPOUNDS AS PI3K-y INHIBITORS
CN108329236B (zh) * 2018-04-04 2020-12-29 盐城师范学院 一种恩杂鲁胺中间体的制备方法
WO2020010003A1 (en) 2018-07-02 2020-01-09 Incyte Corporation AMINOPYRAZINE DERIVATIVES AS PI3K-γ INHIBITORS
US20220306640A1 (en) * 2019-09-06 2022-09-29 Ono Pharmaceutical Co., Ltd. Hydantoin derivative
WO2025103470A1 (zh) * 2023-11-17 2025-05-22 中国药科大学 作为雄激素受体(ar)拮抗剂的化合物及其应用

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US20150175576A1 (en) 2015-06-25
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