JP6698022B2 - ピリジル部分を有する非ステロイド性抗アンドロゲン及び選択的アンドロゲン受容体モジュレーター - Google Patents

ピリジル部分を有する非ステロイド性抗アンドロゲン及び選択的アンドロゲン受容体モジュレーター Download PDF

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JP6698022B2
JP6698022B2 JP2016541131A JP2016541131A JP6698022B2 JP 6698022 B2 JP6698022 B2 JP 6698022B2 JP 2016541131 A JP2016541131 A JP 2016541131A JP 2016541131 A JP2016541131 A JP 2016541131A JP 6698022 B2 JP6698022 B2 JP 6698022B2
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group
compound
androgen
pharmaceutical composition
inhibitor
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JP2016540819A (ja
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フェルナンド・ラブリ
シャンカル・モハン・シン
リシャール・ラブレック
リヴィウ・コンスタンタン・チョバヌ
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Endorecherche Inc
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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JP2016541131A 2013-12-19 2014-12-16 ピリジル部分を有する非ステロイド性抗アンドロゲン及び選択的アンドロゲン受容体モジュレーター Active JP6698022B2 (ja)

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US201361918133P 2013-12-19 2013-12-19
US61/918,133 2013-12-19
US14/567,970 US9682960B2 (en) 2013-12-19 2014-12-11 Non-steroidal antiandrogens and selective androgen receptor modulators with a pyridyl moiety
US14/567,970 2014-12-11
PCT/CA2014/000894 WO2015089634A1 (en) 2013-12-19 2014-12-16 Non-steroidal antiandrogens and selective androgen receptor modulators with a pyridyl moiety

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US (1) US9682960B2 (enExample)
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US9682960B2 (en) * 2013-12-19 2017-06-20 Endorecherche, Inc. Non-steroidal antiandrogens and selective androgen receptor modulators with a pyridyl moiety
TW201630899A (zh) 2015-01-09 2016-09-01 必治妥美雅史谷比公司 作為ｒｏｃｋ抑制劑的環狀脲類
TWI726969B (zh) 2016-01-11 2021-05-11 比利時商健生藥品公司 用作雄性激素受體拮抗劑之經取代之硫尿囊素衍生物
WO2018005533A1 (en) 2016-07-01 2018-01-04 G1 Therapeutics, Inc. Antiproliferative pyrimidine-based compounds
WO2019226213A2 (en) 2018-03-08 2019-11-28 Incyte Corporation AMINOPYRAZINE DIOL COMPOUNDS AS PI3K-y INHIBITORS
CN108329236B (zh) * 2018-04-04 2020-12-29 盐城师范学院 一种恩杂鲁胺中间体的制备方法
WO2020010003A1 (en) 2018-07-02 2020-01-09 Incyte Corporation AMINOPYRAZINE DERIVATIVES AS PI3K-γ INHIBITORS
US20220306640A1 (en) * 2019-09-06 2022-09-29 Ono Pharmaceutical Co., Ltd. Hydantoin derivative
WO2025103470A1 (zh) * 2023-11-17 2025-05-22 中国药科大学 作为雄激素受体(ar)拮抗剂的化合物及其应用

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