DK291890A - Pyrimidinnucleosider, fremgangsmaade til fremstilling deraf og pyrimidinderivater til anvendelse som mellemprodukter ved fremgangsmaaden samt farmaceutiske praeparater indeholdende pyrimidinnucleosiderne og anvendelse af disse til fremstilling af laegemidler til behandling af aids og infektioner af retrovirus - Google Patents

Pyrimidinnucleosider, fremgangsmaade til fremstilling deraf og pyrimidinderivater til anvendelse som mellemprodukter ved fremgangsmaaden samt farmaceutiske praeparater indeholdende pyrimidinnucleosiderne og anvendelse af disse til fremstilling af laegemidler til behandling af aids og infektioner af retrovirus Download PDF

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DK291890A
DK291890A DK291890A DK291890A DK291890A DK 291890 A DK291890 A DK 291890A DK 291890 A DK291890 A DK 291890A DK 291890 A DK291890 A DK 291890A DK 291890 A DK291890 A DK 291890A
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compounds
piratures
pyrimin
substate
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DK291890D0 (da
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Karl Nils Gunnar Johansson
Hans C G Malmberg
Rolf Noreen
S Christer Sahlberg
Daniel D Sohn
Salo Gronowitz
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Medivir Ab
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/34One oxygen atom
    • C07D239/36One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06Pyrimidine radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06Pyrimidine radicals
    • C07H19/10Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK291890A 1988-06-10 1990-12-07 Pyrimidinnucleosider, fremgangsmaade til fremstilling deraf og pyrimidinderivater til anvendelse som mellemprodukter ved fremgangsmaaden samt farmaceutiske praeparater indeholdende pyrimidinnucleosiderne og anvendelse af disse til fremstilling af laegemidler til behandling af aids og infektioner af retrovirus DK291890A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE8802173A SE8802173D0 (sv) 1988-06-10 1988-06-10 Pyrimidine derivatives
PCT/SE1989/000322 WO1989012061A1 (en) 1988-06-10 1989-06-07 Pyrimidine nucleosides and intermediates

Publications (2)

Publication Number Publication Date
DK291890D0 DK291890D0 (da) 1990-12-07
DK291890A true DK291890A (da) 1991-02-07

Family

ID=20372582

Family Applications (1)

Application Number Title Priority Date Filing Date
DK291890A DK291890A (da) 1988-06-10 1990-12-07 Pyrimidinnucleosider, fremgangsmaade til fremstilling deraf og pyrimidinderivater til anvendelse som mellemprodukter ved fremgangsmaaden samt farmaceutiske praeparater indeholdende pyrimidinnucleosiderne og anvendelse af disse til fremstilling af laegemidler til behandling af aids og infektioner af retrovirus

Country Status (20)

Country Link
US (2) US5440040A (no)
EP (2) EP0357571B1 (no)
JP (1) JP2851094B2 (no)
KR (1) KR900701815A (no)
AT (1) ATE136308T1 (no)
AU (1) AU637574B2 (no)
CA (1) CA1339313C (no)
DE (1) DE68926137T2 (no)
DK (1) DK291890A (no)
ES (1) ES2087090T3 (no)
FI (1) FI94643C (no)
GR (1) GR3020212T3 (no)
HU (1) HU211736B (no)
IE (1) IE62914B1 (no)
MY (1) MY109743A (no)
NO (1) NO175981C (no)
PH (1) PH27219A (no)
PT (1) PT90803B (no)
SE (1) SE8802173D0 (no)
WO (1) WO1989012061A1 (no)

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Also Published As

Publication number Publication date
SE8802173D0 (sv) 1988-06-10
US5440040A (en) 1995-08-08
JPH03504969A (ja) 1991-10-31
NO905300D0 (no) 1990-12-07
JP2851094B2 (ja) 1999-01-27
PT90803B (pt) 1994-10-31
AU637574B2 (en) 1993-06-03
FI94643C (fi) 1995-10-10
PT90803A (pt) 1989-12-29
EP0357571A2 (en) 1990-03-07
HUT57230A (en) 1991-11-28
EP0691333A2 (en) 1996-01-10
WO1989012061A1 (en) 1989-12-14
DK291890D0 (da) 1990-12-07
FI94643B (fi) 1995-06-30
EP0357571B1 (en) 1996-04-03
ATE136308T1 (de) 1996-04-15
KR900701815A (ko) 1990-12-04
ES2087090T3 (es) 1996-07-16
IE62914B1 (en) 1995-03-08
FI906053A0 (fi) 1990-12-07
NO175981B (no) 1994-10-03
NO905300L (no) 1991-02-06
DE68926137T2 (de) 1996-11-14
HU894340D0 (en) 1991-08-28
EP0691333A3 (no) 1996-02-14
DE68926137D1 (de) 1996-05-09
US5576429A (en) 1996-11-19
AU3750489A (en) 1990-01-05
EP0357571A3 (en) 1990-06-13
NO175981C (no) 1995-01-11
GR3020212T3 (en) 1996-09-30
CA1339313C (en) 1997-08-19
IE891816L (en) 1989-12-10
MY109743A (en) 1997-05-31
HU211736B (en) 1995-12-28
PH27219A (en) 1993-05-04

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