DK2879685T3 - Sammensætninger til et medicinsk udstyr omfattende exopolysaccharide-producerende bakteriestammer i forbindelse med vegetabilske gummier og/eller vegetabilske gelatiner - Google Patents

Sammensætninger til et medicinsk udstyr omfattende exopolysaccharide-producerende bakteriestammer i forbindelse med vegetabilske gummier og/eller vegetabilske gelatiner Download PDF

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DK2879685T3
DK2879685T3 DK13777111.9T DK13777111T DK2879685T3 DK 2879685 T3 DK2879685 T3 DK 2879685T3 DK 13777111 T DK13777111 T DK 13777111T DK 2879685 T3 DK2879685 T3 DK 2879685T3
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streptococcus thermophilus
vegetable
dsm
alternatively
gelatin
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DK13777111.9T
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Giovanni Mogna
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Probiotical Spa
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747Lactobacilli, e.g. L. acidophilus or L. brevis
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/20Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/20Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
    • A23L29/206Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of vegetable origin
    • A23L29/238Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of vegetable origin from seeds, e.g. locust bean gum or guar gum
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/20Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
    • A23L29/206Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of vegetable origin
    • A23L29/256Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of vegetable origin from seaweeds, e.g. alginates, agar or carrageenan
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/20Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
    • A23L29/275Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of animal origin, e.g. chitin
    • A23L29/281Proteins, e.g. gelatin or collagen
    • A23L29/284Gelatin; Collagen
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135Bacteria or derivatives thereof, e.g. probiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7024Esters of saccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02Algae
    • A61K36/03Phaeophycota or phaeophyta (brown algae), e.g. Fucus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/886Aloeaceae (Aloe family), e.g. aloe vera
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K2035/11Medicinal preparations comprising living procariotic cells
    • A61K2035/115Probiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Inorganic Chemistry (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Botany (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Claims (6)

1. Sammensætning til et medicinsk udstyr omfattende et specifikt slimhindeklæbende gelleringskompleks bestående af EPS, exopolysaccharider af bakteriel oprindelse produceret in situ i mavetarmkanalen af specifikt valgte bakteriestammer, i forbindelse med vegetabilske gummier og/eller vegetabilske gelatiner, til anvendelse som et lægemiddel til forebyggelsen og behandlingen af patologier forbundet til en defekt i barriereeffekten i mavetarmområdet på grund af en lav produktion af slim valgt fra infektioner, såsom infektioner af patogene bakterier, inflammationer og lidelser i mavetarmkanalen og candidiasis, hvor: - nævnte defekt i barriereeffekten i mavetarmområdet på grund af en lav produktion af slim sker i tilfældet af tarmpermeabilitet og af en bakteriel translokation, - nævnte exopolysaccharid-producerende bakteriestammer er valgt fra gruppen af bakterier tilhørende arten Streptococcus thermophilus og er i stand til at producere exopolysaccharider in situ i mavetarmkanalen til at beskytte tarmslimhinden mod virkningen af patogene bakterier, hvor nævnte bakterier af Streptococcus thermophilus-arten er valgt fra gruppen omfattende eller, alternativt, bestående af: - Streptococcus thermophilus DSM 16590 (Y02), deponeret hos deponeringsinstitutionen DSMZ i Tyskland den 20.07.2004, - Streptococcus thermophilus DSM 16592 (Y04), deponeret hos deponeringsinstitutionen DSMZ i Tyskland den 20.07.2004, - Streptococcus thermophilus DSM 17843 (Y08), deponeret hos deponeringsinstitutionen DSMZ i Tyskland den 21.12.2005, - Streptococcus thermophilus DSM 25246 (ST10), deponeret hos deponeringsinstitutionen DSMZ i Tyskland den 19.09.2011, - Streptococcus thermophilus DSM 25247 (ST11), deponeret hos deponeringsinstitutionen DSMZ i Tyskland den 19.09.2011, - Streptococcus thermophilus DSM 25282 (ST12), deponeret hos deponeringsinstitutionen DSMZ i Tyskland den 19.09.2011, og - nævnte vegetabilske gummier og/eller vegetabilske gelatiner er valgt fra gruppen bestående af Aloe gelatine, Aloe vera gelatine eller Aloe arborescens gelatine, eller taragummi.
2. Sammensætningen til anvendelse ifølge krav 1, hvor nævnte exopolysaccharide-producerende Streptococcus thermophilus bakteriestammer er i blanding med bakterier valgt fra gruppen af bakterier tilhørende arten Lactobacillus plantarum og/eller Lactobacillus rhamnosus og/eller Streptococcus thermophilus og er i stand til at producere exopolysaccharider in situ i mavetarmkanalen til at beskytte tarmslimhinden mod virkningen af patogene bakterier.
3. Sammensætningen til anvendelse ifølge et af de foregående krav 1-2, hvor nævnte sammensætning omfatter eller, alternativt, består af mindst en bakteriestamme valgt fra gruppen omfattende eller, alternativt, bestående af: Streptococcus thermophilus DSM 16590 (Y02), Streptococcus thermophilus DSM 16592 (Y04), Streptococcus thermophilus DSM 17843 (Y08) og Streptococcus thermophilus DSM 25246 (STIO) i forbindelse med en vegetabilsk gummi og/eller en animalsk og/eller vegetabilsk gelatine valgt fra gruppen omfattende eller, alternativt, bestående af Aloe arborescens gelatine og taragummi.
4. Sammensætningen til anvendelse ifølge krav 3, hvor nævnte sammensætning omfatter eller, alternativt, består af: Streptococcus thermophilus DSM 25246 (STIO) i forbindelse med en vegetabilsk gummi og/eller en animalsk og/eller vegetabilsk gelatine valgt fra gruppen omfattende eller, alternativt, bestående af Aloe arborescens gelatine og taragummi; fortrinsvis taragummi.
5. Sammensætningen til anvendelse ifølge krav 3, hvor nævnte sammensætning omfatter eller, alternativt, består af: Streptococcus thermophilus DSM 25246 (STIO) og mindst en stamme valgt fra blandt Streptococcus thermophilus DSM 16590 (Y02), Streptococcus thermophilus DSM 16592 (Y04) og Streptococcus thermophilus DSM 17843 (Y08) i forbindelse med en vegetabilsk gummi og/eller en animalsk og/eller vegetabilsk gelatine valgt fra gruppen omfattende eller, alternativt, bestående af Aloe arborescens gelatine og taragummi; fortrinsvis taragummi.
6. Sammensætningen til anvendelse ifølge krav 3, hvor nævnte sammensætning omfatter eller, alternativt, består af: Streptococcus thermophilus DSM 25246 (STIO) og Streptococcus thermophilus DSM 16592 (Y04) i forbindelse med en vegetabilsk gummi og/eller en animalsk og/eller vegetabilsk gelatine valgt fra gruppen omfattende eller, alternativt, bestående af Aloe arborescens gelatine og taragummi; fortrinsvis taragummi.
DK13777111.9T 2012-07-30 2013-07-30 Sammensætninger til et medicinsk udstyr omfattende exopolysaccharide-producerende bakteriestammer i forbindelse med vegetabilske gummier og/eller vegetabilske gelatiner DK2879685T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT001328A ITMI20121328A1 (it) 2012-07-30 2012-07-30 Composizione per dispositivo medico comprendente ceppi di batteri produttori di esopolisaccaridi in associazione con gomme e/o gelatine.
PCT/IB2013/001668 WO2014020408A1 (en) 2012-07-30 2013-07-30 Compositions for a medical device comprising exopolysaccharide-producing bacterial strains in association with gums and/or gelatines

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DK2879685T3 true DK2879685T3 (da) 2017-12-11

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US (2) US9889166B2 (da)
EP (1) EP2879685B1 (da)
KR (1) KR20150038435A (da)
CN (1) CN104540512A (da)
BR (1) BR112015002054A2 (da)
CA (1) CA2879014A1 (da)
DK (1) DK2879685T3 (da)
ES (1) ES2650455T3 (da)
IN (1) IN2015MN00094A (da)
IT (1) ITMI20121328A1 (da)
PL (1) PL2879685T3 (da)
PT (1) PT2879685T (da)
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ITMI20121328A1 (it) 2012-07-30 2014-01-31 Probiotical Spa Composizione per dispositivo medico comprendente ceppi di batteri produttori di esopolisaccaridi in associazione con gomme e/o gelatine.
ES2750152T3 (es) * 2014-04-15 2020-03-25 Devintec Sagl Composiciones a base de xiloglucano y proteínas para el tratamiento de trastornos intestinales
KR20160144501A (ko) * 2014-05-05 2016-12-16 지오바니 모그나 L. 류테리 ler03 및/또는 l. 살리바리우스 ls06을 포함하는 항-종양 화학요법, 백혈병 치료 또는 보조 요법을 받는 개체에서 바이러스 또는 박테리아 감염을 치료하거나 예방하는데 사용하기 위한 조성물
RU2730005C2 (ru) * 2014-11-26 2020-08-14 Пробиотикал С.П.А Штаммы Lactobacillus или Bifidobacterium для поддержания гомеостаза
ITUB20155700A1 (it) * 2015-11-18 2017-05-18 Probiotical Spa Composizioni con azione sinergica tra un complesso gelificante muco-aderente contro il passaggio degli antigeni, e batteri immunomodulanti anti-IL17 per uso nel trattamento delle malattie autoimmuni e neurodegenerative IL17 dipendenti.

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ITMI20121328A1 (it) 2012-07-30 2014-01-31 Probiotical Spa Composizione per dispositivo medico comprendente ceppi di batteri produttori di esopolisaccaridi in associazione con gomme e/o gelatine.

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Publication number Publication date
ES2650455T3 (es) 2018-01-18
US9889166B2 (en) 2018-02-13
RU2646486C2 (ru) 2018-03-05
PL2879685T3 (pl) 2018-03-30
EP2879685A1 (en) 2015-06-10
IN2015MN00094A (da) 2015-10-16
EP2879685B1 (en) 2017-09-20
WO2014020408A1 (en) 2014-02-06
PT2879685T (pt) 2017-12-12
ITMI20121328A1 (it) 2014-01-31
BR112015002054A2 (pt) 2017-07-04
CN104540512A (zh) 2015-04-22
RU2015104728A (ru) 2016-09-20
CA2879014A1 (en) 2014-02-06
US20150202239A1 (en) 2015-07-23
KR20150038435A (ko) 2015-04-08
US20180133268A1 (en) 2018-05-17

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