DK28787A - Thieno-1,4-diazepinforbindelser samt farmaceutiske praeparater med indhold af saadanne forbindelser - Google Patents

Thieno-1,4-diazepinforbindelser samt farmaceutiske praeparater med indhold af saadanne forbindelser

Info

Publication number
DK28787A
DK28787A DK028787A DK28787A DK28787A DK 28787 A DK28787 A DK 28787A DK 028787 A DK028787 A DK 028787A DK 28787 A DK28787 A DK 28787A DK 28787 A DK28787 A DK 28787A
Authority
DK
Denmark
Prior art keywords
compounds
thieno
pharmaceutical preparations
preparations containing
diazepine
Prior art date
Application number
DK028787A
Other languages
Danish (da)
English (en)
Other versions
DK28787D0 (da
Inventor
Dr Werner Stransky
Dr Karl-Heinz Weber
Dr Gerhard Walther
Dr Albrecht Harreus
Dr Jorge Casals Stenzel
Dr Gojko Muacevic
Dr Wolf-Dietrich Bechtel
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of DK28787D0 publication Critical patent/DK28787D0/da
Publication of DK28787A publication Critical patent/DK28787A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DK028787A 1986-01-21 1987-01-20 Thieno-1,4-diazepinforbindelser samt farmaceutiske praeparater med indhold af saadanne forbindelser DK28787A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3601557 1986-01-21
DE3624646 1986-07-22

Publications (2)

Publication Number Publication Date
DK28787D0 DK28787D0 (da) 1987-01-20
DK28787A true DK28787A (da) 1987-07-22

Family

ID=25840265

Family Applications (1)

Application Number Title Priority Date Filing Date
DK028787A DK28787A (da) 1986-01-21 1987-01-20 Thieno-1,4-diazepinforbindelser samt farmaceutiske praeparater med indhold af saadanne forbindelser

Country Status (18)

Country Link
US (1) US4900729A (fr)
EP (1) EP0230942B1 (fr)
KR (1) KR870007180A (fr)
AU (1) AU594739B2 (fr)
CA (1) CA1314880C (fr)
DE (1) DE3778559D1 (fr)
DK (1) DK28787A (fr)
ES (1) ES2037013T3 (fr)
FI (1) FI870192A (fr)
GR (1) GR3004475T3 (fr)
HU (1) HUT45258A (fr)
IL (1) IL81322A0 (fr)
NO (1) NO166367C (fr)
NZ (1) NZ219015A (fr)
PH (1) PH27029A (fr)
PL (1) PL263736A1 (fr)
PT (1) PT84149B (fr)
YU (1) YU6687A (fr)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3502392A1 (de) * 1985-01-25 1986-07-31 Boehringer Ingelheim KG, 6507 Ingelheim Neue thieno-triazolo-1,4-diazepino-2- carbonsaeureamide, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen
DE3610848A1 (de) * 1986-04-01 1987-10-15 Boehringer Ingelheim Kg Neue 1,4-diazepine
PH30676A (en) * 1986-07-22 1997-09-16 Boehringer Ingelhein Kg Hetrazepine compounds which have useful pharmaceutical utility
DE3878833T2 (de) * 1987-05-28 1993-06-09 Yoshitomi Pharmaceutical Thieno(triazolo)diazepinverbindungen, und medizinische verwendung derselben.
EP0316456A4 (fr) * 1987-06-08 1990-05-14 Yoshitomi Pharmaceutical Composes de thienotriazolodiazepine a substitution ether et leur utilisation en medecine.
US5480881A (en) * 1990-06-01 1996-01-02 Korth; Ruth Treatment of disease with paf-acether antagonists and procedure determining their efficacy
EP0540767B9 (fr) * 1991-11-04 2004-12-22 Korth, Ruth-Maria, Dr. med Traitement et prévention de maladies mentales, induites par des taux de lyso-PAF élevés, avec des antagonistes du PAF
US5530023A (en) * 1987-10-20 1996-06-25 Korth; Ruth Production of binding sites for PAF, PAF analogues and PAF antagonists in endothelial cells
US5895785A (en) * 1987-10-20 1999-04-20 Ruth Korth Treatment and prevention of disorders mediated by LA-paf or endothelial cells
EP0540766A1 (fr) * 1991-11-04 1993-05-12 Korth, Ruth-Maria, Dr. med Traitement des maladies induites par les éosinophiles avec des antagonistes du PAF, et procédé pour en déterminer l'efficacité
MC1999A1 (fr) * 1987-12-18 1990-01-26 Hoffmann La Roche Composes tricycliques
CA1324863C (fr) * 1988-01-30 1993-11-30 Minoru Moriwaki Composes thienotriazolodiazepine et leurs utilisations pharmaceutiques
EP0338993A1 (fr) * 1988-04-21 1989-10-25 Sandoz Ag 4H-thiéno[2,3-e][1,2,4]triazolo[3,4-c][1,4]diazépines substituées par aryle sur la position 6
CA1322367C (fr) * 1988-05-17 1993-09-21 Yoshitomi Pharmaceutical Industries Ltd. Composes thienotrizolodiazepine et leurs utilisations pharmaceutiques
IL91386A0 (en) * 1988-08-24 1990-04-29 Boehringer Ingelheim Kg Method for treating autoimmune diseases by using a paf antagonist and pharmaceutical compositions comprising it
RU2117670C1 (ru) * 1988-10-31 1998-08-20 Эйсай Ко., Лтд. Производные триазоло[1,4]диазепина и способы их получения
FI95708C (fi) 1988-10-31 1996-03-11 Eisai Co Ltd Analogiamenetelmä 1,4-diatsepiinijohdannaisen ja sen farmaseuttisesti sopivan suolan valmistamiseksi
EP0387613A1 (fr) * 1989-03-03 1990-09-19 Boehringer Ingelheim Kg Thiénodiazépines
DK0389189T3 (da) * 1989-03-23 1994-06-20 Pfizer Diazepin antiallergimidler
EP0407955A1 (fr) * 1989-07-12 1991-01-16 Boehringer Ingelheim Kg Hétrazépines à activité PAF antagonistique, procédé pour leur préparation et leur utilisation comme médicaments
FR2659332B1 (fr) * 1990-03-08 1994-04-29 Adit Et Cie Nouvelles pyrrolo [1,2-a] thieno [3,2-f] diazepines [1,4], leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
DE4010528A1 (de) * 1990-04-02 1991-10-17 Boehringer Ingelheim Kg Praeparativ chromatographisches trennverfahren zur herstellung enantiomerenreiner hetrazepine
DE4027470A1 (de) * 1990-08-30 1992-03-05 Boehringer Ingelheim Kg Neue hetrazepinoide amide
DE4107521A1 (de) * 1991-03-08 1992-09-10 Boehringer Ingelheim Kg Neue acylaminosubstituierte hetrazepine
AU2003230754B2 (en) * 2002-03-28 2007-10-25 Wisys Technology Foundation, Inc. Anxiolytic agents with reduced sedative and ataxic effects
US20100261711A1 (en) * 2009-03-20 2010-10-14 Wisys Technology Foundation Selective anticonvulsant agents and their uses
JP2017504651A (ja) 2014-01-31 2017-02-09 ダナ−ファーバー キャンサー インスティテュート, インコーポレイテッド ジアゼパン誘導体の使用
KR101675984B1 (ko) * 2015-02-23 2016-11-14 한양대학교 에리카산학협력단 티에노디아제핀 유도체 또는 이의 약학적으로 허용가능한 염, 및 이를 유효성분으로 포함하는 약학적 조성물
CA2996974A1 (fr) * 2015-09-11 2017-03-16 Dana-Farber Cancer Institute, Inc. Cyano-thienotriazoloazepines et leurs utilisations
EP3380100A4 (fr) 2015-11-25 2019-10-02 Dana-Farber Cancer Institute, Inc. Inhibiteurs de bromodomaines bivalents et leurs utilisations

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4969667A (fr) * 1972-11-06 1974-07-05
PH12303A (en) * 1973-02-08 1979-01-16 Hoffmann La Roche Thienotriazolodiazepine derivatives
CH612972A5 (en) * 1974-01-16 1979-08-31 Hoffmann La Roche Process for the preparation of thieno-triazolo-diazepine derivatives
US4307237A (en) * 1974-09-11 1981-12-22 Hoffmann-La Roche Inc. Imidazoles
FI63033C (fi) * 1977-07-21 1983-04-11 Boehringer Sohn Ingelheim Foerfarande foer framstaellning av anxiolytiska tranquilliserande sedativa och/eller neuroleptiska substituerade 1-piperazinyl-4h-s-triazolo(3,4-c)tieno(2,3-e)-1,4-diazepiner
DE3435973A1 (de) * 1984-10-01 1986-04-10 Boehringer Ingelheim KG, 6507 Ingelheim Diazepine enthaltende pharmazeutische zusammensetzungen mit paf-antagonistischer wirkung
DE3502392A1 (de) * 1985-01-25 1986-07-31 Boehringer Ingelheim KG, 6507 Ingelheim Neue thieno-triazolo-1,4-diazepino-2- carbonsaeureamide, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen
DE3610848A1 (de) * 1986-04-01 1987-10-15 Boehringer Ingelheim Kg Neue 1,4-diazepine
PH30676A (en) * 1986-07-22 1997-09-16 Boehringer Ingelhein Kg Hetrazepine compounds which have useful pharmaceutical utility

Also Published As

Publication number Publication date
NO166367B (no) 1991-04-02
FI870192A0 (fi) 1987-01-19
EP0230942A3 (en) 1989-03-08
AU594739B2 (en) 1990-03-15
GR3004475T3 (fr) 1993-03-31
FI870192A (fi) 1987-07-22
DK28787D0 (da) 1987-01-20
NO870240D0 (no) 1987-01-20
ES2037013T3 (es) 1993-06-16
NO166367C (no) 1991-07-10
YU6687A (en) 1990-12-31
PT84149A (de) 1987-02-01
EP0230942A2 (fr) 1987-08-05
DE3778559D1 (de) 1992-06-04
PH27029A (en) 1993-02-01
PT84149B (pt) 1989-07-31
EP0230942B1 (fr) 1992-04-29
PL263736A1 (en) 1988-07-21
CA1314880C (fr) 1993-03-23
US4900729A (en) 1990-02-13
AU6784587A (en) 1987-07-23
IL81322A0 (en) 1987-08-31
NZ219015A (en) 1990-01-29
KR870007180A (ko) 1987-08-17
NO870240L (no) 1987-07-22
HUT45258A (en) 1988-06-28

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Legal Events

Date Code Title Description
A0 Application filed
AHB Application shelved due to non-payment