PT84149B - Processo para a preparacao de novas tieno-1,4-diazepinas e de composicoes farmaceuticas que as contem - Google Patents
Processo para a preparacao de novas tieno-1,4-diazepinas e de composicoes farmaceuticas que as contemInfo
- Publication number
- PT84149B PT84149B PT84149A PT8414987A PT84149B PT 84149 B PT84149 B PT 84149B PT 84149 A PT84149 A PT 84149A PT 8414987 A PT8414987 A PT 8414987A PT 84149 B PT84149 B PT 84149B
- Authority
- PT
- Portugal
- Prior art keywords
- diazepins
- thien
- pharmaceutical compositions
- compositions containing
- preparing new
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3601557 | 1986-01-21 | ||
| DE3624646 | 1986-07-22 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT84149A PT84149A (de) | 1987-02-01 |
| PT84149B true PT84149B (pt) | 1989-07-31 |
Family
ID=25840265
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT84149A PT84149B (pt) | 1986-01-21 | 1987-01-20 | Processo para a preparacao de novas tieno-1,4-diazepinas e de composicoes farmaceuticas que as contem |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4900729A (pt) |
| EP (1) | EP0230942B1 (pt) |
| KR (1) | KR870007180A (pt) |
| AU (1) | AU594739B2 (pt) |
| CA (1) | CA1314880C (pt) |
| DE (1) | DE3778559D1 (pt) |
| DK (1) | DK28787A (pt) |
| ES (1) | ES2037013T3 (pt) |
| FI (1) | FI870192A (pt) |
| GR (1) | GR3004475T3 (pt) |
| HU (1) | HUT45258A (pt) |
| IL (1) | IL81322A0 (pt) |
| NO (1) | NO166367C (pt) |
| NZ (1) | NZ219015A (pt) |
| PH (1) | PH27029A (pt) |
| PL (1) | PL263736A1 (pt) |
| PT (1) | PT84149B (pt) |
| YU (1) | YU6687A (pt) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3502392A1 (de) * | 1985-01-25 | 1986-07-31 | Boehringer Ingelheim KG, 6507 Ingelheim | Neue thieno-triazolo-1,4-diazepino-2- carbonsaeureamide, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen |
| DE3610848A1 (de) * | 1986-04-01 | 1987-10-15 | Boehringer Ingelheim Kg | Neue 1,4-diazepine |
| PH30676A (en) * | 1986-07-22 | 1997-09-16 | Boehringer Ingelhein Kg | Hetrazepine compounds which have useful pharmaceutical utility |
| US4960770A (en) * | 1987-05-28 | 1990-10-02 | Yoshitomi Pharmaceutical Industries, Ltd. | 2-alkyl thieno(triazolo)diazepine compounds and pharmaceutical uses thereof |
| WO1988009792A1 (en) * | 1987-06-08 | 1988-12-15 | Yoshitomi Pharmaceutical Industries, Ltd. | Ester-substituted thienotriazolodiazepine compounds and their medicinal use |
| US5895785A (en) * | 1987-10-20 | 1999-04-20 | Ruth Korth | Treatment and prevention of disorders mediated by LA-paf or endothelial cells |
| US5480881A (en) * | 1990-06-01 | 1996-01-02 | Korth; Ruth | Treatment of disease with paf-acether antagonists and procedure determining their efficacy |
| US5530023A (en) * | 1987-10-20 | 1996-06-25 | Korth; Ruth | Production of binding sites for PAF, PAF analogues and PAF antagonists in endothelial cells |
| MC1999A1 (fr) * | 1987-12-18 | 1990-01-26 | Hoffmann La Roche | Composes tricycliques |
| CA1324863C (en) * | 1988-01-30 | 1993-11-30 | Minoru Moriwaki | Thienotriazolodiazepine compounds and pharmaceutical uses thereof |
| EP0338993A1 (en) * | 1988-04-21 | 1989-10-25 | Sandoz Ag | 6-Aryl-substituted-4h-thieno[2,3-e][1,2,4]triazolo [3,4-c][1,4]diazepines |
| CA1322367C (en) * | 1988-05-17 | 1993-09-21 | Yoshitomi Pharmaceutical Industries Ltd. | Thienotriazolodiazepine compounds and pharmaceutical uses thereof |
| IL91386A0 (en) * | 1988-08-24 | 1990-04-29 | Boehringer Ingelheim Kg | Method for treating autoimmune diseases by using a paf antagonist and pharmaceutical compositions comprising it |
| FI95708C (fi) | 1988-10-31 | 1996-03-11 | Eisai Co Ltd | Analogiamenetelmä 1,4-diatsepiinijohdannaisen ja sen farmaseuttisesti sopivan suolan valmistamiseksi |
| RU2117670C1 (ru) * | 1988-10-31 | 1998-08-20 | Эйсай Ко., Лтд. | Производные триазоло[1,4]диазепина и способы их получения |
| EP0387613A1 (de) * | 1989-03-03 | 1990-09-19 | Boehringer Ingelheim Kg | Neue Thienodiazepine |
| ES2052172T3 (es) * | 1989-03-23 | 1994-07-01 | Pfizer | Agentes antialergicos basados en diazepina. |
| EP0407955A1 (de) * | 1989-07-12 | 1991-01-16 | Boehringer Ingelheim Kg | Neue Hetrazepine mit PAF-antagonistischer Wirkung, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| FR2659332B1 (fr) * | 1990-03-08 | 1994-04-29 | Adit Et Cie | Nouvelles pyrrolo [1,2-a] thieno [3,2-f] diazepines [1,4], leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| DE4010528A1 (de) * | 1990-04-02 | 1991-10-17 | Boehringer Ingelheim Kg | Praeparativ chromatographisches trennverfahren zur herstellung enantiomerenreiner hetrazepine |
| DE4027470A1 (de) * | 1990-08-30 | 1992-03-05 | Boehringer Ingelheim Kg | Neue hetrazepinoide amide |
| DE4107521A1 (de) * | 1991-03-08 | 1992-09-10 | Boehringer Ingelheim Kg | Neue acylaminosubstituierte hetrazepine |
| DE540766T1 (de) * | 1991-11-04 | 2002-11-28 | Ruth-Maria Korth | Behandlung von Eosinophil-mediierten Erkrankungen mit PAF-Antagonisten, und Verfahren zur Bestimmung deren Effektivität. |
| ES2181665T3 (es) * | 1991-11-04 | 2003-03-01 | Ruth-Maria Korth | Tratamiento y prevencion de enfermedades mentales, acompañadas por unos elevados niveles de liso paf, con los antagonistas de paf. |
| DE60319812T2 (de) * | 2002-03-28 | 2009-04-23 | Wisys Technology Foundation, Inc., Madison | Angstlösende wirkstoffe mit verminderten beruhigenden und ataktischen nebenwirkungen |
| US20100261711A1 (en) * | 2009-03-20 | 2010-10-14 | Wisys Technology Foundation | Selective anticonvulsant agents and their uses |
| JP2017504651A (ja) | 2014-01-31 | 2017-02-09 | ダナ−ファーバー キャンサー インスティテュート， インコーポレイテッド | ジアゼパン誘導体の使用 |
| KR101675984B1 (ko) * | 2015-02-23 | 2016-11-14 | 한양대학교 에리카산학협력단 | 티에노디아제핀 유도체 또는 이의 약학적으로 허용가능한 염, 및 이를 유효성분으로 포함하는 약학적 조성물 |
| RU2750164C2 (ru) | 2015-09-11 | 2021-06-22 | Дана-Фарбер Кэнсер Инститьют, Инк. | Цианотиенотриазолодиазепины и пути их применения |
| CR20180336A (es) | 2015-11-25 | 2018-08-06 | Dana Farber Cancer Inst Inc | Inhibidores de bromodominio bivalentes y usos de los mismos |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4969667A (pt) * | 1972-11-06 | 1974-07-05 | ||
| PH12303A (en) * | 1973-02-08 | 1979-01-16 | Hoffmann La Roche | Thienotriazolodiazepine derivatives |
| CH612972A5 (en) * | 1974-01-16 | 1979-08-31 | Hoffmann La Roche | Process for the preparation of thieno-triazolo-diazepine derivatives |
| US4307237A (en) * | 1974-09-11 | 1981-12-22 | Hoffmann-La Roche Inc. | Imidazoles |
| FI63033C (fi) * | 1977-07-21 | 1983-04-11 | Boehringer Sohn Ingelheim | Foerfarande foer framstaellning av anxiolytiska tranquilliserande sedativa och/eller neuroleptiska substituerade 1-piperazinyl-4h-s-triazolo(3,4-c)tieno(2,3-e)-1,4-diazepiner |
| DE3435973A1 (de) * | 1984-10-01 | 1986-04-10 | Boehringer Ingelheim KG, 6507 Ingelheim | Diazepine enthaltende pharmazeutische zusammensetzungen mit paf-antagonistischer wirkung |
| DE3502392A1 (de) * | 1985-01-25 | 1986-07-31 | Boehringer Ingelheim KG, 6507 Ingelheim | Neue thieno-triazolo-1,4-diazepino-2- carbonsaeureamide, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen |
| DE3610848A1 (de) * | 1986-04-01 | 1987-10-15 | Boehringer Ingelheim Kg | Neue 1,4-diazepine |
| PH30676A (en) * | 1986-07-22 | 1997-09-16 | Boehringer Ingelhein Kg | Hetrazepine compounds which have useful pharmaceutical utility |
-
1987
- 1987-01-17 ES ES198787100593T patent/ES2037013T3/es not_active Expired - Lifetime
- 1987-01-17 EP EP87100593A patent/EP0230942B1/de not_active Expired - Lifetime
- 1987-01-17 DE DE8787100593T patent/DE3778559D1/de not_active Expired - Lifetime
- 1987-01-19 YU YU00066/87A patent/YU6687A/xx unknown
- 1987-01-19 FI FI870192A patent/FI870192A/fi not_active Application Discontinuation
- 1987-01-20 PT PT84149A patent/PT84149B/pt not_active IP Right Cessation
- 1987-01-20 KR KR870000416A patent/KR870007180A/ko not_active Application Discontinuation
- 1987-01-20 DK DK028787A patent/DK28787A/da not_active Application Discontinuation
- 1987-01-20 CA CA000527655A patent/CA1314880C/en not_active Expired - Fee Related
- 1987-01-20 IL IL81322A patent/IL81322A0/xx unknown
- 1987-01-20 PL PL1987263736A patent/PL263736A1/xx unknown
- 1987-01-20 NO NO870240A patent/NO166367C/no unknown
- 1987-01-20 HU HU87153A patent/HUT45258A/hu unknown
- 1987-01-21 PH PH34750A patent/PH27029A/en unknown
- 1987-01-21 NZ NZ219015A patent/NZ219015A/xx unknown
- 1987-01-21 AU AU67845/87A patent/AU594739B2/en not_active Ceased
-
1988
- 1988-10-11 US US07/255,903 patent/US4900729A/en not_active Expired - Fee Related
-
1992
- 1992-04-30 GR GR920400788T patent/GR3004475T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PH27029A (en) | 1993-02-01 |
| EP0230942A3 (en) | 1989-03-08 |
| US4900729A (en) | 1990-02-13 |
| CA1314880C (en) | 1993-03-23 |
| DK28787A (da) | 1987-07-22 |
| NO870240D0 (no) | 1987-01-20 |
| PT84149A (de) | 1987-02-01 |
| NO166367C (no) | 1991-07-10 |
| AU594739B2 (en) | 1990-03-15 |
| AU6784587A (en) | 1987-07-23 |
| EP0230942A2 (de) | 1987-08-05 |
| PL263736A1 (en) | 1988-07-21 |
| NO870240L (no) | 1987-07-22 |
| YU6687A (en) | 1990-12-31 |
| GR3004475T3 (pt) | 1993-03-31 |
| DK28787D0 (da) | 1987-01-20 |
| NO166367B (no) | 1991-04-02 |
| IL81322A0 (en) | 1987-08-31 |
| FI870192A0 (fi) | 1987-01-19 |
| KR870007180A (ko) | 1987-08-17 |
| DE3778559D1 (de) | 1992-06-04 |
| ES2037013T3 (es) | 1993-06-16 |
| EP0230942B1 (de) | 1992-04-29 |
| HUT45258A (en) | 1988-06-28 |
| NZ219015A (en) | 1990-01-29 |
| FI870192A (fi) | 1987-07-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PT84149B (pt) | Processo para a preparacao de novas tieno-1,4-diazepinas e de composicoes farmaceuticas que as contem | |
| PT92368A (pt) | Processo para a preparacao de novas quinuclidinas e de composicoes farmaceuticas que as contem | |
| PT83013B (pt) | Processo para a preparacao de hidroxialquilxantinas terciarias, e de composicoes farmaceuticas que as contem | |
| PT84569B (pt) | Processo para a preparacao de tiazepinas e de composicoes farmaceuticas que os contem | |
| PT81746B (pt) | Processo para a preparacao de peptido-aldeidos e de composicoes farmaceuticas que os contem | |
| PT89009A (pt) | Processo para a preparacao de novos derivados de fluorocitidina e composicoes farmaceuticas que os contem | |
| PT81362B (pt) | Processo para a preparacao de 9-amino-1,2,3,4-tetra-hidroacridin-1-ol e compostos relacionados e de composicoes farmaceuticas que os contem | |
| PT80724B (pt) | Processo para a preparacao de novos derivados de gangliosidos e de composicoes farmaceuticas que os contem | |
| PT81969B (pt) | Processo para preparacao de 11 beta-fenil-esteroides e de composicoes farmaceuticas que os contem | |
| PT87201A (pt) | Processo para a preparacao de novos derivados de cefalosporina 3,7-substituida e de composicoes farmaceuticas que os contem | |
| PT87913A (pt) | Processo para a preparacao de derivados de benzopirano e de composicoes farmaceuticas que os contem | |
| PT81650B (pt) | Processo para a preparacao de novas pteridinas e de composicoes farmaceuticas que as contem | |
| PT88914A (pt) | Processo para a preparacao de polipeptidos e de composicoes farmaceuticas que os contem | |
| PT84828B (pt) | Processo para a preparacao de compostos heterociclicos triciclicos fundidos e de composicoes farmaceuticas que os contem | |
| PT80246B (pt) | Processo para a preparacao de novos derivados de cefalosporina e de composicoes farmaceuticas que os contem | |
| PT84358B (pt) | Processo para a preparacao de naftotiazepinonas e de composicoes farmaceuticas que as contem | |
| PT90142A (pt) | Processo para a preparacao de novos imidazois substituidos em 2,3 e 4 e de 1,2,4-triazois substituido4 em 3,4 e 5 bem como de composicoes farmaceuticas que os contem | |
| PT81659B (pt) | Processo para a preparacao de aminoacil-labdanos e de composicoes farmaceuticas que os contem | |
| PT82984B (pt) | Processo para a preparacao de derivados de poli-4-aminopirrole-2-carboxamido e de composicoes farmaceuticas que os contem | |
| PT80794B (pt) | Processo para a preparacao de novas isoindolinil-alquilpiperazinas e de composicoes farmaceuticas que as contem | |
| PT89234A (pt) | Processo para a preparacao de novos compostos de amonio e de composicoes farmaceuticas que os contem | |
| PT94902A (pt) | Processo para a preparacao de novos derivados de cromano e de composicoes farmaceuticas que os contem | |
| PT93138A (pt) | Processo para a preparacao de novos compostos derivados da acetamina e de composicoes farmaceuticas que os contem | |
| PT87115A (pt) | Processo para a preparacao de derivados da dihidropiridazinona e de composicoes farmaceuticas que os contem | |
| PT87090A (pt) | Processo para a preparacao de derivados de imidazopiridinas e de composicoes farmaceuticas que os contem |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19940731 |