FI870192A - Nya tieno-1,4-diazepiner. - Google Patents

Nya tieno-1,4-diazepiner. Download PDF

Info

Publication number
FI870192A
FI870192A FI870192A FI870192A FI870192A FI 870192 A FI870192 A FI 870192A FI 870192 A FI870192 A FI 870192A FI 870192 A FI870192 A FI 870192A FI 870192 A FI870192 A FI 870192A
Authority
FI
Finland
Prior art keywords
diazepiner
tieno
nya
nya tieno
Prior art date
Application number
FI870192A
Other languages
English (en)
Other versions
FI870192A0 (fi
Inventor
Werner Stransky
Karl-Heinz Weber
Gerhard Walther
Albrecht Harreus
Jorge Casals Stenzel
Gojko Muacevic
Wolf-Dietrich Bechtel
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of FI870192A0 publication Critical patent/FI870192A0/fi
Publication of FI870192A publication Critical patent/FI870192A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
FI870192A 1986-01-21 1987-01-19 Nya tieno-1,4-diazepiner. FI870192A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3601557 1986-01-21
DE3624646 1986-07-22

Publications (2)

Publication Number Publication Date
FI870192A0 FI870192A0 (fi) 1987-01-19
FI870192A true FI870192A (fi) 1987-07-22

Family

ID=25840265

Family Applications (1)

Application Number Title Priority Date Filing Date
FI870192A FI870192A (fi) 1986-01-21 1987-01-19 Nya tieno-1,4-diazepiner.

Country Status (18)

Country Link
US (1) US4900729A (fi)
EP (1) EP0230942B1 (fi)
KR (1) KR870007180A (fi)
AU (1) AU594739B2 (fi)
CA (1) CA1314880C (fi)
DE (1) DE3778559D1 (fi)
DK (1) DK28787A (fi)
ES (1) ES2037013T3 (fi)
FI (1) FI870192A (fi)
GR (1) GR3004475T3 (fi)
HU (1) HUT45258A (fi)
IL (1) IL81322A0 (fi)
NO (1) NO166367C (fi)
NZ (1) NZ219015A (fi)
PH (1) PH27029A (fi)
PL (1) PL263736A1 (fi)
PT (1) PT84149B (fi)
YU (1) YU6687A (fi)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3502392A1 (de) * 1985-01-25 1986-07-31 Boehringer Ingelheim KG, 6507 Ingelheim Neue thieno-triazolo-1,4-diazepino-2- carbonsaeureamide, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen
DE3610848A1 (de) * 1986-04-01 1987-10-15 Boehringer Ingelheim Kg Neue 1,4-diazepine
PH30676A (en) * 1986-07-22 1997-09-16 Boehringer Ingelhein Kg Hetrazepine compounds which have useful pharmaceutical utility
ATE86256T1 (de) * 1987-05-28 1993-03-15 Yoshitomi Pharmaceutical Thieno(triazolo)diazepinverbindungen, und medizinische verwendung derselben.
WO1988009792A1 (en) * 1987-06-08 1988-12-15 Yoshitomi Pharmaceutical Industries, Ltd. Ester-substituted thienotriazolodiazepine compounds and their medicinal use
US5895785A (en) * 1987-10-20 1999-04-20 Ruth Korth Treatment and prevention of disorders mediated by LA-paf or endothelial cells
US5480881A (en) * 1990-06-01 1996-01-02 Korth; Ruth Treatment of disease with paf-acether antagonists and procedure determining their efficacy
US5530023A (en) * 1987-10-20 1996-06-25 Korth; Ruth Production of binding sites for PAF, PAF analogues and PAF antagonists in endothelial cells
MC1999A1 (fr) * 1987-12-18 1990-01-26 Hoffmann La Roche Composes tricycliques
CA1324863C (en) * 1988-01-30 1993-11-30 Minoru Moriwaki Thienotriazolodiazepine compounds and pharmaceutical uses thereof
EP0338993A1 (en) * 1988-04-21 1989-10-25 Sandoz Ag 6-Aryl-substituted-4h-thieno[2,3-e][1,2,4]triazolo [3,4-c][1,4]diazepines
CA1322367C (en) * 1988-05-17 1993-09-21 Yoshitomi Pharmaceutical Industries Ltd. Thienotriazolodiazepine compounds and pharmaceutical uses thereof
IL91386A0 (en) * 1988-08-24 1990-04-29 Boehringer Ingelheim Kg Method for treating autoimmune diseases by using a paf antagonist and pharmaceutical compositions comprising it
RU2117670C1 (ru) * 1988-10-31 1998-08-20 Эйсай Ко., Лтд. Производные триазоло[1,4]диазепина и способы их получения
FI95708C (fi) * 1988-10-31 1996-03-11 Eisai Co Ltd Analogiamenetelmä 1,4-diatsepiinijohdannaisen ja sen farmaseuttisesti sopivan suolan valmistamiseksi
EP0387613A1 (de) * 1989-03-03 1990-09-19 Boehringer Ingelheim Kg Neue Thienodiazepine
DE69008906T2 (de) * 1989-03-23 1994-08-25 Pfizer Antiallergische Mittel auf der Basis von Diazepin.
YU133090A (sh) * 1989-07-12 1993-10-20 Boehringer Ingelheim Kg. Novi heteroazepini s paf-antaganostičnim učinkom in postopek za njihovo pripravo
FR2659332B1 (fr) * 1990-03-08 1994-04-29 Adit Et Cie Nouvelles pyrrolo [1,2-a] thieno [3,2-f] diazepines [1,4], leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
DE4010528A1 (de) * 1990-04-02 1991-10-17 Boehringer Ingelheim Kg Praeparativ chromatographisches trennverfahren zur herstellung enantiomerenreiner hetrazepine
DE4027470A1 (de) * 1990-08-30 1992-03-05 Boehringer Ingelheim Kg Neue hetrazepinoide amide
DE4107521A1 (de) * 1991-03-08 1992-09-10 Boehringer Ingelheim Kg Neue acylaminosubstituierte hetrazepine
DE540766T1 (de) * 1991-11-04 2002-11-28 Ruth-Maria Korth Behandlung von Eosinophil-mediierten Erkrankungen mit PAF-Antagonisten, und Verfahren zur Bestimmung deren Effektivität.
DE69133083C5 (de) * 1991-11-04 2007-05-31 Korth, Ruth-Maria, Dr.med. Behandlung und Vorbeugung von erhöhten Lyso-PAF-Spiegel mediierten mentalen Erkrankungen mit PAF-Antagonisten
JP2005525392A (ja) * 2002-03-28 2005-08-25 ウィシス テクノロジー ファウンデーション，インコーポレイティド 減少された鎮静及び失調効果を有する抗不安薬剤
US20100261711A1 (en) * 2009-03-20 2010-10-14 Wisys Technology Foundation Selective anticonvulsant agents and their uses
US10793571B2 (en) 2014-01-31 2020-10-06 Dana-Farber Cancer Institute, Inc. Uses of diazepane derivatives
KR101675984B1 (ko) * 2015-02-23 2016-11-14 한양대학교 에리카산학협력단 티에노디아제핀 유도체 또는 이의 약학적으로 허용가능한 염, 및 이를 유효성분으로 포함하는 약학적 조성물
PE20181287A1 (es) * 2015-09-11 2018-08-07 Dana Farber Cancer Inst Inc Ciano tienotriazolpirazinas y usos de las mismas
PE20181298A1 (es) 2015-11-25 2018-08-07 Dana Farber Cancer Inst Inc Inhibidores de bromodominio bivalentes y usos de los mismos

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4969667A (fi) * 1972-11-06 1974-07-05
PH12303A (en) * 1973-02-08 1979-01-16 Hoffmann La Roche Thienotriazolodiazepine derivatives
CH612972A5 (en) * 1974-01-16 1979-08-31 Hoffmann La Roche Process for the preparation of thieno-triazolo-diazepine derivatives
US4307237A (en) * 1974-09-11 1981-12-22 Hoffmann-La Roche Inc. Imidazoles
FI63033C (fi) * 1977-07-21 1983-04-11 Boehringer Sohn Ingelheim Foerfarande foer framstaellning av anxiolytiska tranquilliserande sedativa och/eller neuroleptiska substituerade 1-piperazinyl-4h-s-triazolo(3,4-c)tieno(2,3-e)-1,4-diazepiner
DE3435973A1 (de) * 1984-10-01 1986-04-10 Boehringer Ingelheim KG, 6507 Ingelheim Diazepine enthaltende pharmazeutische zusammensetzungen mit paf-antagonistischer wirkung
DE3502392A1 (de) * 1985-01-25 1986-07-31 Boehringer Ingelheim KG, 6507 Ingelheim Neue thieno-triazolo-1,4-diazepino-2- carbonsaeureamide, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen
DE3610848A1 (de) * 1986-04-01 1987-10-15 Boehringer Ingelheim Kg Neue 1,4-diazepine
PH30676A (en) * 1986-07-22 1997-09-16 Boehringer Ingelhein Kg Hetrazepine compounds which have useful pharmaceutical utility

Also Published As

Publication number Publication date
NZ219015A (en) 1990-01-29
GR3004475T3 (fi) 1993-03-31
NO870240D0 (no) 1987-01-20
DK28787A (da) 1987-07-22
DE3778559D1 (de) 1992-06-04
PT84149B (pt) 1989-07-31
PL263736A1 (en) 1988-07-21
PT84149A (de) 1987-02-01
US4900729A (en) 1990-02-13
IL81322A0 (en) 1987-08-31
KR870007180A (ko) 1987-08-17
NO166367B (no) 1991-04-02
FI870192A0 (fi) 1987-01-19
AU594739B2 (en) 1990-03-15
NO870240L (no) 1987-07-22
CA1314880C (en) 1993-03-23
YU6687A (en) 1990-12-31
DK28787D0 (da) 1987-01-20
EP0230942A2 (de) 1987-08-05
EP0230942A3 (en) 1989-03-08
ES2037013T3 (es) 1993-06-16
NO166367C (no) 1991-07-10
PH27029A (en) 1993-02-01
AU6784587A (en) 1987-07-23
EP0230942B1 (de) 1992-04-29
HUT45258A (en) 1988-06-28

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Legal Events

Date Code Title Description
FD Application lapsed
FD Application lapsed

Owner name: BOEHRINGER INGELHEIM KG