DK625087D0 - Heteroaromatiske aminoderivater dsamt laegemidler med indhold af saadanne forbindelser - Google Patents
Heteroaromatiske aminoderivater dsamt laegemidler med indhold af saadanne forbindelserInfo
- Publication number
- DK625087D0 DK625087D0 DK625087A DK625087A DK625087D0 DK 625087 D0 DK625087 D0 DK 625087D0 DK 625087 A DK625087 A DK 625087A DK 625087 A DK625087 A DK 625087A DK 625087 D0 DK625087 D0 DK 625087D0
- Authority
- DK
- Denmark
- Prior art keywords
- compounds
- products containing
- medicinal products
- amino derivatives
- heteroaromatic amino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/46—Iso-indoles; Hydrogenated iso-indoles with an oxygen atom in position 1
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19863640641 DE3640641A1 (de) | 1986-11-28 | 1986-11-28 | Neue heteroaromatische aminderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK625087D0 true DK625087D0 (da) | 1987-11-27 |
| DK625087A DK625087A (da) | 1988-05-29 |
Family
ID=6314973
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK625087A DK625087A (da) | 1986-11-28 | 1987-11-27 | Heteroaromatiske aminoderivater dsamt laegemidler med indhold af saadanne forbindelser |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US4912115A (da) |
| EP (1) | EP0269968A3 (da) |
| JP (1) | JPS63150276A (da) |
| KR (1) | KR880006230A (da) |
| AU (1) | AU600995B2 (da) |
| DD (1) | DD270911A5 (da) |
| DE (1) | DE3640641A1 (da) |
| DK (1) | DK625087A (da) |
| FI (1) | FI875233A (da) |
| HU (1) | HU206208B (da) |
| IL (1) | IL84612A (da) |
| NO (1) | NO874955L (da) |
| NZ (1) | NZ222718A (da) |
| PT (1) | PT86227B (da) |
| ZA (1) | ZA878914B (da) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5250538A (en) * | 1990-02-13 | 1993-10-05 | Novo Nordisk A/S | Indole derivatives and their use |
| DK37790A (da) * | 1990-02-13 | 1991-08-14 | Novo Nordisk As | Indolderivater, deres fremstilling og anvendelse |
| US5273994A (en) * | 1990-04-09 | 1993-12-28 | Adir Et Compagnie | 3-aminochroman compounds |
| FR2660657B1 (fr) * | 1990-04-09 | 1993-05-07 | Adir | Nouveaux derives du 3-aminochromane, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| JP2807577B2 (ja) * | 1990-06-15 | 1998-10-08 | エーザイ株式会社 | 環状アミド誘導体 |
| FR2675802B1 (fr) * | 1991-04-26 | 1993-12-24 | Rhone Poulenc Rorer Sa | Antiserotonines, leur preparation et les medicaments les contenant. |
| US7151102B2 (en) | 2000-10-30 | 2006-12-19 | Kudos Pharmaceuticals Limited | Phthalazinone derivatives |
| ATE355278T1 (de) | 2001-05-08 | 2006-03-15 | Kudos Pharm Ltd | Isochinolinon derivate als parp inhibitoren |
| EP1501822B1 (en) | 2002-04-30 | 2010-12-15 | Kudos Pharmaceuticals Limited | Phthalazinone derivatives |
| GB0305681D0 (en) | 2003-03-12 | 2003-04-16 | Kudos Pharm Ltd | Phthalazinone derivatives |
| US7449464B2 (en) | 2003-03-12 | 2008-11-11 | Kudos Pharmaceuticals Limited | Phthalazinone derivatives |
| FR2853649B1 (fr) * | 2003-04-09 | 2006-07-14 | Servier Lab | Nouveaux derives d'isoquinoleine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| GB0419072D0 (en) | 2004-08-26 | 2004-09-29 | Kudos Pharm Ltd | Phthalazinone derivatives |
| GB0521373D0 (en) | 2005-10-20 | 2005-11-30 | Kudos Pharm Ltd | Pthalazinone derivatives |
| US20090023727A1 (en) * | 2007-07-05 | 2009-01-22 | Muhammad Hashim Javaid | Phthalazinone derivatives |
| RU2010108008A (ru) | 2007-09-14 | 2011-10-20 | Астразенека Аб (Se) | Фталазиноновые производные |
| CA2702429A1 (en) | 2007-10-17 | 2009-04-23 | Kudos Pharmaceuticals Limited | Crystalline form l 4-[3-(4-cyclopropanecarbonyl-piperazine-1-carbonyl)-4-fluoro-benzyl]-2h-phthalazin-1-one |
| UY31603A1 (es) | 2008-01-23 | 2009-08-31 | Derivados de ftalazinona | |
| BRPI0920604B1 (pt) | 2008-10-07 | 2021-11-23 | Kudos Pharmaceuticals Limited | Formulação farmacêutica de liberação imediata na forma de uma dispersão sólida compreendendo como ativo o composto 4-[3-(4-ciclopropanocarbonil-piperazina-1-carbonil)-4-flúor- benzil]-2h-ftalazin-1-ona (olaparibe) |
| FR2941695B1 (fr) * | 2009-02-04 | 2011-02-18 | Servier Lab | Nouveau procede de synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable |
| EP2935243B1 (en) * | 2012-12-21 | 2018-03-14 | Epizyme, Inc. | Prmt5 inhibitors containing a dihydro- or tetrahydroisoquinoline and uses thereof |
| DK2935222T3 (da) | 2012-12-21 | 2019-01-07 | Epizyme Inc | Prmt5-inhibitorer og anvendelser deraf |
| WO2016022605A1 (en) | 2014-08-04 | 2016-02-11 | Epizyme, Inc. | Prmt5 inhibitors and uses thereof |
| EP4370110A1 (en) * | 2021-07-16 | 2024-05-22 | Denali Therapeutics Inc. | Compounds, compositions and methods |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3919202A (en) * | 1971-08-06 | 1975-11-11 | Sterling Drug Inc | 3-(Substituted amino)-1H-isoindoles |
| DE2345423A1 (de) * | 1973-09-08 | 1975-03-20 | Thomae Gmbh Dr K | Neue substituierte phenylaethylaminderivate, deren saeureadditionssalze, diese enthaltende arzneimittel sowie verfahren zu deren herstellung |
| US4118494A (en) * | 1974-08-14 | 1978-10-03 | Hoechst Aktiengesellschaft | Substituted 3,4-dihydro-2H-isoquinolin-1-thiones |
| US4087541A (en) * | 1975-03-06 | 1978-05-02 | Boehringer Ingelheim Gmbh | 2-(Aralkylaminoalkyl)phthalimidines |
| AT352135B (de) * | 1975-07-30 | 1979-09-10 | Thomae Gmbh Dr K | Verfahren zur herstellung neuer homophthalimide und ihrer salze |
| DE2639718A1 (de) * | 1976-09-03 | 1978-03-16 | Thomae Gmbh Dr K | Neue phenylaethylamine |
| CH645628A5 (en) * | 1977-01-01 | 1984-10-15 | Thomae Gmbh Dr K | Phenylethylamines |
| US4375471A (en) * | 1981-02-19 | 1983-03-01 | Hoechst-Roussel Pharmaceuticals Inc. | 4-Aryloxy-1,2,3,4-tetrahydroisoquinolines |
| FR2546886B2 (fr) * | 1983-06-06 | 1986-05-16 | Adir | Derives d'acides isoindoledicarboxyliques, leur preparation et compositions pharmaceutiques les contenant |
| DE3717561A1 (de) * | 1987-05-25 | 1988-12-08 | Thomae Gmbh Dr K | Indol-, isochinolin- und benzazepinderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
-
1986
- 1986-11-28 DE DE19863640641 patent/DE3640641A1/de not_active Withdrawn
-
1987
- 1987-11-21 EP EP19870117201 patent/EP0269968A3/de not_active Withdrawn
- 1987-11-25 US US07/125,626 patent/US4912115A/en not_active Expired - Fee Related
- 1987-11-26 IL IL84612A patent/IL84612A/xx unknown
- 1987-11-26 PT PT86227A patent/PT86227B/pt not_active IP Right Cessation
- 1987-11-26 DD DD87309530A patent/DD270911A5/de not_active IP Right Cessation
- 1987-11-27 NO NO874955A patent/NO874955L/no unknown
- 1987-11-27 JP JP62299612A patent/JPS63150276A/ja active Pending
- 1987-11-27 DK DK625087A patent/DK625087A/da not_active Application Discontinuation
- 1987-11-27 FI FI875233A patent/FI875233A/fi not_active IP Right Cessation
- 1987-11-27 ZA ZA878914A patent/ZA878914B/xx unknown
- 1987-11-27 NZ NZ222718A patent/NZ222718A/xx unknown
- 1987-11-27 AU AU81876/87A patent/AU600995B2/en not_active Ceased
- 1987-11-27 HU HU875359A patent/HU206208B/hu not_active IP Right Cessation
- 1987-11-27 KR KR870013414A patent/KR880006230A/ko not_active Application Discontinuation
-
1991
- 1991-05-07 US US07/696,677 patent/US5116986A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| KR880006230A (ko) | 1988-07-22 |
| FI875233A0 (fi) | 1987-11-27 |
| AU600995B2 (en) | 1990-08-30 |
| DD270911A5 (de) | 1989-08-16 |
| US4912115A (en) | 1990-03-27 |
| US5116986A (en) | 1992-05-26 |
| HUT48619A (en) | 1989-06-28 |
| NZ222718A (en) | 1990-05-28 |
| DE3640641A1 (de) | 1988-07-14 |
| DK625087A (da) | 1988-05-29 |
| EP0269968A3 (de) | 1990-10-17 |
| AU8187687A (en) | 1988-06-02 |
| EP0269968A2 (de) | 1988-06-08 |
| NO874955L (no) | 1988-05-30 |
| NO874955D0 (no) | 1987-11-27 |
| FI875233A (fi) | 1988-05-29 |
| JPS63150276A (ja) | 1988-06-22 |
| ZA878914B (en) | 1989-07-26 |
| PT86227B (pt) | 1990-11-07 |
| IL84612A0 (en) | 1988-04-29 |
| PT86227A (de) | 1987-12-01 |
| HU206208B (en) | 1992-09-28 |
| IL84612A (en) | 1992-03-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment |