YU6687A - New thieno-1,4-diazepines - Google Patents

New thieno-1,4-diazepines

Info

Publication number
YU6687A
YU6687A YU00066/87A YU6687A YU6687A YU 6687 A YU6687 A YU 6687A YU 00066/87 A YU00066/87 A YU 00066/87A YU 6687 A YU6687 A YU 6687A YU 6687 A YU6687 A YU 6687A
Authority
YU
Yugoslavia
Prior art keywords
diazepines
new thieno
thieno
new
Prior art date
Application number
YU00066/87A
Other languages
English (en)
Inventor
W Stransky
K H Weber
G Walter
A Harreus
J C Stenzel
G Maucevic
W D Bechtel
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of YU6687A publication Critical patent/YU6687A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
YU00066/87A 1986-01-21 1987-01-19 New thieno-1,4-diazepines YU6687A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3601557 1986-01-21
DE3624646 1986-07-22

Publications (1)

Publication Number Publication Date
YU6687A true YU6687A (en) 1990-12-31

Family

ID=25840265

Family Applications (1)

Application Number Title Priority Date Filing Date
YU00066/87A YU6687A (en) 1986-01-21 1987-01-19 New thieno-1,4-diazepines

Country Status (18)

Country Link
US (1) US4900729A (fr)
EP (1) EP0230942B1 (fr)
KR (1) KR870007180A (fr)
AU (1) AU594739B2 (fr)
CA (1) CA1314880C (fr)
DE (1) DE3778559D1 (fr)
DK (1) DK28787A (fr)
ES (1) ES2037013T3 (fr)
FI (1) FI870192A (fr)
GR (1) GR3004475T3 (fr)
HU (1) HUT45258A (fr)
IL (1) IL81322A0 (fr)
NO (1) NO166367C (fr)
NZ (1) NZ219015A (fr)
PH (1) PH27029A (fr)
PL (1) PL263736A1 (fr)
PT (1) PT84149B (fr)
YU (1) YU6687A (fr)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3502392A1 (de) * 1985-01-25 1986-07-31 Boehringer Ingelheim KG, 6507 Ingelheim Neue thieno-triazolo-1,4-diazepino-2- carbonsaeureamide, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen
DE3610848A1 (de) * 1986-04-01 1987-10-15 Boehringer Ingelheim Kg Neue 1,4-diazepine
PH30676A (en) * 1986-07-22 1997-09-16 Boehringer Ingelhein Kg Hetrazepine compounds which have useful pharmaceutical utility
ATE86256T1 (de) * 1987-05-28 1993-03-15 Yoshitomi Pharmaceutical Thieno(triazolo)diazepinverbindungen, und medizinische verwendung derselben.
EP0316456A4 (fr) * 1987-06-08 1990-05-14 Yoshitomi Pharmaceutical Composes de thienotriazolodiazepine a substitution ether et leur utilisation en medecine.
US5530023A (en) * 1987-10-20 1996-06-25 Korth; Ruth Production of binding sites for PAF, PAF analogues and PAF antagonists in endothelial cells
US5480881A (en) * 1990-06-01 1996-01-02 Korth; Ruth Treatment of disease with paf-acether antagonists and procedure determining their efficacy
US5895785A (en) * 1987-10-20 1999-04-20 Ruth Korth Treatment and prevention of disorders mediated by LA-paf or endothelial cells
MC1999A1 (fr) * 1987-12-18 1990-01-26 Hoffmann La Roche Composes tricycliques
CA1324863C (fr) * 1988-01-30 1993-11-30 Minoru Moriwaki Composes thienotriazolodiazepine et leurs utilisations pharmaceutiques
EP0338993A1 (fr) * 1988-04-21 1989-10-25 Sandoz Ag 4H-thiéno[2,3-e][1,2,4]triazolo[3,4-c][1,4]diazépines substituées par aryle sur la position 6
CA1322367C (fr) * 1988-05-17 1993-09-21 Yoshitomi Pharmaceutical Industries Ltd. Composes thienotrizolodiazepine et leurs utilisations pharmaceutiques
IL91386A0 (en) * 1988-08-24 1990-04-29 Boehringer Ingelheim Kg Method for treating autoimmune diseases by using a paf antagonist and pharmaceutical compositions comprising it
FI95708C (fi) * 1988-10-31 1996-03-11 Eisai Co Ltd Analogiamenetelmä 1,4-diatsepiinijohdannaisen ja sen farmaseuttisesti sopivan suolan valmistamiseksi
RU2117670C1 (ru) * 1988-10-31 1998-08-20 Эйсай Ко., Лтд. Производные триазоло[1,4]диазепина и способы их получения
EP0387613A1 (fr) * 1989-03-03 1990-09-19 Boehringer Ingelheim Kg Thiénodiazépines
ES2052172T3 (es) * 1989-03-23 1994-07-01 Pfizer Agentes antialergicos basados en diazepina.
YU133090A (sh) * 1989-07-12 1993-10-20 Boehringer Ingelheim Kg. Novi heteroazepini s paf-antaganostičnim učinkom in postopek za njihovo pripravo
FR2659332B1 (fr) * 1990-03-08 1994-04-29 Adit Et Cie Nouvelles pyrrolo [1,2-a] thieno [3,2-f] diazepines [1,4], leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
DE4010528A1 (de) * 1990-04-02 1991-10-17 Boehringer Ingelheim Kg Praeparativ chromatographisches trennverfahren zur herstellung enantiomerenreiner hetrazepine
DE4027470A1 (de) * 1990-08-30 1992-03-05 Boehringer Ingelheim Kg Neue hetrazepinoide amide
DE4107521A1 (de) * 1991-03-08 1992-09-10 Boehringer Ingelheim Kg Neue acylaminosubstituierte hetrazepine
DE540766T1 (de) * 1991-11-04 2002-11-28 Ruth-Maria Korth Behandlung von Eosinophil-mediierten Erkrankungen mit PAF-Antagonisten, und Verfahren zur Bestimmung deren Effektivität.
ATE221779T1 (de) * 1991-11-04 2002-08-15 Ruth-Maria Korth Behandlung und vorbeugung von erhöhten lyso-paf- spiegel mediierten mentalen erkrankungen mit paf- antagonisten
ATE389640T1 (de) * 2002-03-28 2008-04-15 Wisys Technology Found Inc Angstlösende wirkstoffe mit verminderten beruhigenden und ataktischen nebenwirkungen
US20100261711A1 (en) * 2009-03-20 2010-10-14 Wisys Technology Foundation Selective anticonvulsant agents and their uses
EP3099693A4 (fr) 2014-01-31 2017-08-16 Dana-Farber Cancer Institute, Inc. Utilisations des dérivés de diazépane
KR101675984B1 (ko) * 2015-02-23 2016-11-14 한양대학교 에리카산학협력단 티에노디아제핀 유도체 또는 이의 약학적으로 허용가능한 염, 및 이를 유효성분으로 포함하는 약학적 조성물
WO2017044849A1 (fr) 2015-09-11 2017-03-16 Dana-Farber Cancer Institute, Inc. Cyano-thiénotriazoloazépines et leurs utilisations
SG10201913450PA (en) 2015-11-25 2020-03-30 Dana Farber Cancer Inst Inc Bivalent bromodomain inhibitors and uses thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4969667A (fr) * 1972-11-06 1974-07-05
PH12303A (en) * 1973-02-08 1979-01-16 Hoffmann La Roche Thienotriazolodiazepine derivatives
CH612972A5 (en) * 1974-01-16 1979-08-31 Hoffmann La Roche Process for the preparation of thieno-triazolo-diazepine derivatives
US4307237A (en) * 1974-09-11 1981-12-22 Hoffmann-La Roche Inc. Imidazoles
FI63033C (fi) * 1977-07-21 1983-04-11 Boehringer Sohn Ingelheim Foerfarande foer framstaellning av anxiolytiska tranquilliserande sedativa och/eller neuroleptiska substituerade 1-piperazinyl-4h-s-triazolo(3,4-c)tieno(2,3-e)-1,4-diazepiner
DE3435973A1 (de) * 1984-10-01 1986-04-10 Boehringer Ingelheim KG, 6507 Ingelheim Diazepine enthaltende pharmazeutische zusammensetzungen mit paf-antagonistischer wirkung
DE3502392A1 (de) * 1985-01-25 1986-07-31 Boehringer Ingelheim KG, 6507 Ingelheim Neue thieno-triazolo-1,4-diazepino-2- carbonsaeureamide, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen
DE3610848A1 (de) * 1986-04-01 1987-10-15 Boehringer Ingelheim Kg Neue 1,4-diazepine
PH30676A (en) * 1986-07-22 1997-09-16 Boehringer Ingelhein Kg Hetrazepine compounds which have useful pharmaceutical utility

Also Published As

Publication number Publication date
AU594739B2 (en) 1990-03-15
NO870240L (no) 1987-07-22
AU6784587A (en) 1987-07-23
ES2037013T3 (es) 1993-06-16
FI870192A (fi) 1987-07-22
PT84149A (de) 1987-02-01
EP0230942A2 (fr) 1987-08-05
PL263736A1 (en) 1988-07-21
FI870192A0 (fi) 1987-01-19
EP0230942B1 (fr) 1992-04-29
US4900729A (en) 1990-02-13
HUT45258A (en) 1988-06-28
NO166367C (no) 1991-07-10
IL81322A0 (en) 1987-08-31
DE3778559D1 (de) 1992-06-04
EP0230942A3 (en) 1989-03-08
CA1314880C (fr) 1993-03-23
DK28787D0 (da) 1987-01-20
KR870007180A (ko) 1987-08-17
GR3004475T3 (fr) 1993-03-31
PH27029A (en) 1993-02-01
NZ219015A (en) 1990-01-29
PT84149B (pt) 1989-07-31
NO870240D0 (no) 1987-01-20
NO166367B (no) 1991-04-02
DK28787A (da) 1987-07-22

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