DK2861568T3 - Tertiære aminer til anvendelse til behandling af hjertesygdomme - Google Patents
Tertiære aminer til anvendelse til behandling af hjertesygdomme Download PDFInfo
- Publication number
- DK2861568T3 DK2861568T3 DK13723783.0T DK13723783T DK2861568T3 DK 2861568 T3 DK2861568 T3 DK 2861568T3 DK 13723783 T DK13723783 T DK 13723783T DK 2861568 T3 DK2861568 T3 DK 2861568T3
- Authority
- DK
- Denmark
- Prior art keywords
- tertiary amines
- disease treatment
- health disease
- health
- treatment
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
- C07C211/27—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring having amino groups linked to the six-membered aromatic ring by saturated carbon chains
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
- C07C211/29—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/43—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/43—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- C07C211/44—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to only one six-membered aromatic ring
- C07C211/49—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to only one six-membered aromatic ring having at least two amino groups bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
- C07C217/58—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms with amino groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/38—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/40—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/28—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1208775.5A GB201208775D0 (en) | 2012-05-18 | 2012-05-18 | Chemical compounds |
PCT/EP2013/060263 WO2013171332A2 (en) | 2012-05-18 | 2013-05-17 | Tertiary amines for use in the treatment of cardiac disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2861568T3 true DK2861568T3 (da) | 2019-06-17 |
Family
ID=46546292
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK13723783.0T DK2861568T3 (da) | 2012-05-18 | 2013-05-17 | Tertiære aminer til anvendelse til behandling af hjertesygdomme |
Country Status (9)
Country | Link |
---|---|
US (2) | US9556111B2 (da) |
EP (1) | EP2861568B1 (da) |
JP (1) | JP6397398B2 (da) |
DK (1) | DK2861568T3 (da) |
ES (1) | ES2731525T3 (da) |
GB (1) | GB201208775D0 (da) |
PL (1) | PL2861568T3 (da) |
TR (1) | TR201908770T4 (da) |
WO (1) | WO2013171332A2 (da) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB201320506D0 (en) | 2013-11-26 | 2014-01-01 | Uni I Oslo | Cyclic amino compounds for the use in the treatment of cardiac disorders |
CN112174829B (zh) * | 2020-10-27 | 2022-11-18 | 山东阳谷华泰化工股份有限公司 | 一种二苄胺的制备方法 |
WO2024119431A1 (en) * | 2022-12-08 | 2024-06-13 | Westlake University | Apoe4 and lilrb3, variants and uses thereof |
Family Cites Families (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3634316A (en) * | 1968-08-23 | 1972-01-11 | Showa Denko Kk | Sulfur-vulcanizable natural and synthetic rubbery polymers containing xylylene diamines as antiozonants |
JPS496302B1 (da) * | 1968-09-30 | 1974-02-13 | ||
GB1263987A (en) * | 1969-05-30 | 1972-02-16 | Allen & Hanburys Ltd | Phenethylamine derivatives |
BE757601A (fr) | 1969-10-17 | 1971-04-16 | Geigy Ag J R | Derives basiques du pyrrole et medicaments renfermant de tels composes |
DE2150293A1 (de) * | 1971-10-08 | 1973-04-12 | Hoechst Ag | Fasern und faeden aus modifizierten synthetischen linearen polyestern mit verbesserter faerbbarkeit |
NL8105170A (nl) * | 1980-12-10 | 1982-07-01 | Thomae Gmbh Dr K | Nieuwe fenylalkylaminen, werkwijze ter bereiding daarvan en de toepassing daarvan als geneesmiddelen. |
JPS62252746A (ja) * | 1986-04-24 | 1987-11-04 | Mitsubishi Chem Ind Ltd | 3級アミンの製造方法 |
JPS63302364A (ja) * | 1987-06-02 | 1988-12-09 | Terumo Corp | ペルオキシドフェニル化合物およびその製造法 |
US5871945A (en) | 1994-11-23 | 1999-02-16 | Icos Corporation | Modulators of anchoring protein function |
JPH08217731A (ja) * | 1995-02-10 | 1996-08-27 | Takeda Chem Ind Ltd | キノン誘導体 |
DE19824922A1 (de) * | 1998-06-04 | 1999-12-09 | Boehringer Ingelheim Pharma | Neue substituierte Indolinone, ihre Herstellung und ihre Verwendung als Arzneimittel |
WO1999065864A2 (de) * | 1998-06-18 | 1999-12-23 | Merck Patent Gmbh | Geminal substituierte amine |
AU1177200A (en) * | 1998-11-10 | 2000-05-29 | Meiji Seika Kaisha Ltd. | Novel imidazo(5,1-B)thiazole derivatives and fungicides containing the same as the active ingredient |
US6723743B1 (en) | 1999-09-28 | 2004-04-20 | Neurogen Corporation | High affinity small molecule C5a receptor modulators |
US6958214B2 (en) | 2000-07-10 | 2005-10-25 | Sequenom, Inc. | Polymorphic kinase anchor proteins and nucleic acids encoding the same |
US20050119246A1 (en) | 2001-12-28 | 2005-06-02 | Bayer Pharmaceuticals Corporation | 1H-pyrazolyl derivative compounds, for use in diseases associated with the 5-ht2c receptor |
CA2484676A1 (en) | 2002-05-03 | 2003-11-13 | Sequenom, Inc. | Kinase anchor protein muteins, peptides thereof, and related methods |
ES2473581T3 (es) | 2002-05-31 | 2014-07-07 | Proteotech Inc. | Compuestos, composiciones y métodos para el tratamiento de amiloidosis y sinucleinopat�as tales como la enfermedad de Alzheimer, la diabetes de tipo 2 y la enfermedad de Parkinson |
EP1537142B1 (de) | 2002-09-06 | 2011-06-29 | Forschungsverbund Berlin e.V. | Akap18 delta, eine neue spleissvariante eines proteinkinase a-ankerproteins und verwendung dieser |
US20050282814A1 (en) | 2002-10-03 | 2005-12-22 | Targegen, Inc. | Vasculostatic agents and methods of use thereof |
ITGE20020104A1 (it) * | 2002-11-22 | 2004-05-23 | Fabrizio Parodi | Composizioni polimeriche rapidamente riscaldabili |
CA2518238A1 (en) | 2003-03-07 | 2004-09-23 | Sequenom, Inc. | Association of polymorphic kinase anchor proteins with cardiac phenotypes and related methods |
US8883160B2 (en) | 2004-02-13 | 2014-11-11 | Ibc Pharmaceuticals, Inc. | Dock-and-lock (DNL) complexes for therapeutic and diagnostic use |
DE102004031579B4 (de) | 2004-06-29 | 2012-12-27 | Forschungsverbund Berlin E.V. | Peptide zur Inhibition der Interaktion von Proteinkinase A und Proteinkinase A-Ankerproteinen, diese umfassendes Nukleinsäuremolekül, Vektor, Wirtszelle, gegen diese gerichtetes Erkennungsmolekül, diese enthaltende pharmazeutische Zusammensetzung, diese enthaltender Kit und deren Verwendung |
BRPI0513444A (pt) | 2004-07-21 | 2008-05-06 | Pfizer Prod Inc | antagonistas do receptor da histamina 3 |
GB0421356D0 (en) | 2004-09-24 | 2004-10-27 | Univ Oslo | Inhibitors |
GB0421355D0 (en) | 2004-09-24 | 2004-10-27 | Univ Oslo | Inhibitors |
US20090176773A1 (en) | 2005-05-18 | 2009-07-09 | Forschungsverbund Berlin E.V. | Non-Peptidic Inhibitors of AKAP/PKA Interaction |
GB0518027D0 (en) | 2005-09-05 | 2005-10-12 | Birkeland Innovasjon As | Compounds |
EP1777230A1 (en) * | 2005-10-19 | 2007-04-25 | LG Chem Ltd. | Multinuclear half metallocene catalyst and method for preparing syndiotactic polystyrene using the same |
JP4216844B2 (ja) * | 2005-10-31 | 2009-01-28 | エルジー・ケム・リミテッド | 新たな多核ハーフメタロセン触媒系及びそれを利用したシンジオタクチックポリスチレンの製造 |
CN100383112C (zh) * | 2006-06-12 | 2008-04-23 | 清华大学 | 一种还原硝基苄胺化合物为氨基苄胺盐酸盐的方法 |
EP2098226A1 (de) | 2008-03-06 | 2009-09-09 | Forschungsverbund Berlin e.V. | AKAP-PKA-Interaktionshemmer zur Anwendung in der Behandlung von Herzkrankheiten |
WO2010010359A2 (en) * | 2008-07-24 | 2010-01-28 | Cilpa Limited | A process for the preparation of cinacalcet and its salts |
FR2940289B1 (fr) | 2008-12-23 | 2014-09-12 | Biopharmed | Derives de la classe des hydroxyquinoleines aminees pour le traitement du cancer du pancreas |
HU1000676D0 (en) * | 2010-12-17 | 2011-02-28 | Pharmahungary 2000 Kft | Inhibitors of matrix metalloproteinase, pharmaceutical compositions thereof and use of them for preventing and treating diseases where the activation of mmp is involved |
-
2012
- 2012-05-18 GB GBGB1208775.5A patent/GB201208775D0/en not_active Ceased
-
2013
- 2013-05-17 EP EP13723783.0A patent/EP2861568B1/en active Active
- 2013-05-17 TR TR2019/08770T patent/TR201908770T4/tr unknown
- 2013-05-17 DK DK13723783.0T patent/DK2861568T3/da active
- 2013-05-17 ES ES13723783T patent/ES2731525T3/es active Active
- 2013-05-17 JP JP2015512079A patent/JP6397398B2/ja active Active
- 2013-05-17 WO PCT/EP2013/060263 patent/WO2013171332A2/en active Application Filing
- 2013-05-17 PL PL13723783T patent/PL2861568T3/pl unknown
- 2013-05-17 US US14/402,037 patent/US9556111B2/en active Active
-
2016
- 2016-12-15 US US15/380,613 patent/US9951033B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
WO2013171332A2 (en) | 2013-11-21 |
EP2861568B1 (en) | 2019-04-17 |
ES2731525T3 (es) | 2019-11-15 |
US9951033B2 (en) | 2018-04-24 |
WO2013171332A3 (en) | 2014-04-17 |
US20150133510A1 (en) | 2015-05-14 |
US20170158657A1 (en) | 2017-06-08 |
TR201908770T4 (tr) | 2019-07-22 |
JP6397398B2 (ja) | 2018-09-26 |
PL2861568T3 (pl) | 2019-11-29 |
GB201208775D0 (en) | 2012-07-04 |
JP2015522537A (ja) | 2015-08-06 |
US9556111B2 (en) | 2017-01-31 |
EP2861568A2 (en) | 2015-04-22 |
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