DK2716684T3 - Forbindelser til forebyggelsen og behandlingen af adhæsionsprocessen - Google Patents

Forbindelser til forebyggelsen og behandlingen af adhæsionsprocessen Download PDF

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Publication number
DK2716684T3
DK2716684T3 DK12785811.6T DK12785811T DK2716684T3 DK 2716684 T3 DK2716684 T3 DK 2716684T3 DK 12785811 T DK12785811 T DK 12785811T DK 2716684 T3 DK2716684 T3 DK 2716684T3
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DK
Denmark
Prior art keywords
relationships
prevention
treatment
adhesion process
adhesion
Prior art date
Application number
DK12785811.6T
Other languages
English (en)
Inventor
Mikhail Gennadievich Shurygin
Irina Aleksandrovna Shurygina
Original Assignee
Pharmasyntez
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from RU2011119848/15A external-priority patent/RU2011119848A/ru
Application filed by Pharmasyntez filed Critical Pharmasyntez
Application granted granted Critical
Publication of DK2716684T3 publication Critical patent/DK2716684T3/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/06Polycondensates having nitrogen-containing heterocyclic rings in the main chain of the macromolecule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02Polyamines
    • C08G73/0206Polyalkylene(poly)amines
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/06Polycondensates having nitrogen-containing heterocyclic rings in the main chain of the macromolecule
    • C08G73/0605Polycondensates containing five-membered rings, not condensed with other rings, with nitrogen atoms as the only ring hetero atoms
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L79/00Compositions of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing nitrogen with or without oxygen or carbon only, not provided for in groups C08L61/00 - C08L77/00
    • C08L79/04Polycondensates having nitrogen-containing heterocyclic rings in the main chain; Polyhydrazides; Polyamide acids or similar polyimide precursors
    • C08L79/06Polyhydrazides; Polytriazoles; Polyamino-triazoles; Polyoxadiazoles

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Surgery (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Materials For Medical Uses (AREA)
DK12785811.6T 2011-05-17 2012-05-17 Forbindelser til forebyggelsen og behandlingen af adhæsionsprocessen DK2716684T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
RU2011119848/15A RU2011119848A (ru) 2011-05-17 2011-05-17 Способ профилактики спайкообразования
RU2011153043 2011-12-26
PCT/IB2012/052483 WO2012156938A1 (ru) 2011-05-17 2012-05-17 Соединения, фармацевтические композиции и способ профилактики и лечения спаечного процесса

Publications (1)

Publication Number Publication Date
DK2716684T3 true DK2716684T3 (da) 2019-09-30

Family

ID=47176372

Family Applications (1)

Application Number Title Priority Date Filing Date
DK12785811.6T DK2716684T3 (da) 2011-05-17 2012-05-17 Forbindelser til forebyggelsen og behandlingen af adhæsionsprocessen

Country Status (31)

Country Link
US (2) US10172952B2 (da)
EP (2) EP2716684B1 (da)
JP (2) JP5936683B2 (da)
KR (2) KR20170034950A (da)
CN (1) CN103534293B (da)
AP (1) AP3694A (da)
AU (3) AU2012257347A1 (da)
BR (1) BR112013029616B1 (da)
CA (1) CA2836268C (da)
CL (1) CL2013003305A1 (da)
CO (1) CO6801779A2 (da)
CR (1) CR20130600A (da)
CY (1) CY1122190T1 (da)
DK (1) DK2716684T3 (da)
DO (1) DOP2013000266A (da)
EA (1) EA025493B1 (da)
GE (1) GEP201706614B (da)
HK (1) HK1189012A1 (da)
IL (1) IL229423B (da)
LT (1) LT2716684T (da)
MA (1) MA35189B1 (da)
MX (2) MX369019B (da)
NI (1) NI201300124A (da)
PE (1) PE20141161A1 (da)
PL (1) PL2716684T3 (da)
RS (1) RS59382B1 (da)
RU (1) RU2582975C2 (da)
SI (1) SI2716684T1 (da)
SV (1) SV2013004582A (da)
WO (1) WO2012156938A1 (da)
ZA (1) ZA201308542B (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103534293B (zh) * 2011-05-17 2015-10-21 法玛西泰股份公司 用于粘连治疗和预防的化合物、化合物相关的药物组合物及用于预防和治疗粘连的方法
RU2745965C1 (ru) * 2020-11-23 2021-04-05 Галина Анатольевна Пучкина Способ профилактики послеоперационного спаечного процесса органов малого таза
RU2749435C1 (ru) * 2020-11-27 2021-06-10 Федеральное государственное бюджетное научное учреждение "Иркутский научный центр хирургии и травматологии" Способ лечения энтеральной недостаточности при воспалительных и травматических повреждениях брюшины

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA945363B (en) * 1993-07-21 1995-03-14 Smithkline Beecham Corp Novel compounds
US20020028798A1 (en) * 1995-12-12 2002-03-07 Omeros Medical Systems Irrigation solution and method for inhibition of pain and inflammation
WO1997005878A1 (en) * 1995-08-10 1997-02-20 Merck & Co., Inc. 2,5-substituted aryl pyrroles, compositions containing such compounds and methods of use
US5837719A (en) * 1995-08-10 1998-11-17 Merck & Co., Inc. 2,5-substituted aryl pyrroles, compositions containing such compounds and methods of use
US5894971A (en) 1998-02-02 1999-04-20 Huang; Te Chien Tool holder for attaching tools to user's hand
US6521223B1 (en) 2000-02-14 2003-02-18 Genzyme Corporation Single phase gels for the prevention of adhesions
WO2002014285A1 (en) * 2000-08-17 2002-02-21 Pfizer Limited Substituted imidazoles as tafia inhibitors
AU2003249977A1 (en) * 2002-07-05 2004-01-23 Axxima Pharmaceuticals Ag Imidazole compounds for the treatment of hepatitis c virus infections
WO2004060405A2 (en) * 2002-12-30 2004-07-22 Angiotech International Ag Tissue reactive compounds and compositions and uses thereof
CN101443044A (zh) * 2005-09-22 2009-05-27 哈达斯特医学研究服务与开发有限公司 治疗活性化合物的葡聚糖和阿拉伯半乳聚糖结合物
WO2008099829A1 (ja) * 2007-02-14 2008-08-21 Japan Science And Technology Agency 実験動物の腸管癒着を形成する方法、腸管癒着実験動物の製造方法、腸管癒着抑制剤のスクリーニング方法及び腸管癒着抑制剤
CN101848739A (zh) * 2007-08-28 2010-09-29 T·阿萨纳夏季斯 手术用水凝胶
RU2363476C1 (ru) 2007-12-20 2009-08-10 Марина Сергеевна Гомон Способ профилактики образования послеоперационных спаек
WO2009103821A2 (de) * 2008-02-23 2009-08-27 Virologik Gmbh Mittel zur behandlung von virusinfektionen
US8205286B1 (en) 2008-10-21 2012-06-26 Milagros Diaz Pillow for female breasts
CN103534293B (zh) * 2011-05-17 2015-10-21 法玛西泰股份公司 用于粘连治疗和预防的化合物、化合物相关的药物组合物及用于预防和治疗粘连的方法
CA2846143A1 (en) 2013-03-13 2014-09-13 Evan J. Falck Helmet pillow

Also Published As

Publication number Publication date
RU2582975C2 (ru) 2016-04-27
CL2013003305A1 (es) 2014-07-18
IL229423A0 (en) 2014-01-30
EA201301275A1 (ru) 2014-03-31
PL2716684T3 (pl) 2020-01-31
MX2013013409A (es) 2014-07-11
CY1122190T1 (el) 2020-11-25
US10493164B2 (en) 2019-12-03
CA2836268A1 (en) 2012-11-22
MX2019011386A (es) 2019-10-30
ZA201308542B (en) 2014-07-30
EP2716684B1 (en) 2019-06-26
AP3694A (en) 2016-04-30
MA35189B1 (fr) 2014-06-02
AU2017221883B2 (en) 2019-06-20
BR112013029616A2 (pt) 2020-08-25
HK1189012A1 (en) 2014-05-23
JP5936683B2 (ja) 2016-06-22
CN103534293B (zh) 2015-10-21
CA2836268C (en) 2018-07-03
AP2013007258A0 (en) 2013-11-30
BR112013029616B1 (pt) 2022-09-20
CN103534293A (zh) 2014-01-22
CO6801779A2 (es) 2013-11-29
EA025493B1 (ru) 2016-12-30
NZ618882A (en) 2016-03-31
NI201300124A (es) 2014-02-25
US20140079663A1 (en) 2014-03-20
SV2013004582A (es) 2018-11-12
AU2015213303A1 (en) 2015-09-03
WO2012156938A1 (ru) 2012-11-22
MX369019B (es) 2019-10-24
EP2716684A4 (en) 2015-07-15
RS59382B1 (sr) 2019-11-29
US10172952B2 (en) 2019-01-08
SI2716684T1 (sl) 2019-11-29
JP2016175931A (ja) 2016-10-06
AU2017221883A1 (en) 2017-09-28
KR20170034950A (ko) 2017-03-29
PE20141161A1 (es) 2014-10-01
US20190125886A1 (en) 2019-05-02
JP2014515057A (ja) 2014-06-26
CR20130600A (es) 2014-04-29
EP2716684A1 (en) 2014-04-09
LT2716684T (lt) 2019-09-25
IL229423B (en) 2018-04-30
EP3569636A1 (en) 2019-11-20
AU2012257347A1 (en) 2014-01-09
KR20140074259A (ko) 2014-06-17
DOP2013000266A (es) 2014-06-01
RU2013155582A (ru) 2015-06-27
GEP201706614B (en) 2017-02-10

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