DK264181A - Benzopyranforbindelser og syreadditionssalte deraf deres fremstilling og anvendelse - Google Patents
Benzopyranforbindelser og syreadditionssalte deraf deres fremstilling og anvendelseInfo
- Publication number
- DK264181A DK264181A DK264181A DK264181A DK264181A DK 264181 A DK264181 A DK 264181A DK 264181 A DK264181 A DK 264181A DK 264181 A DK264181 A DK 264181A DK 264181 A DK264181 A DK 264181A
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- acid addition
- addition salts
- benzopyrane
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/64—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with oxygen atoms directly attached in position 8
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/66—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8084180 | 1980-06-17 | ||
JP8084180A JPS6054317B2 (ja) | 1980-06-17 | 1980-06-17 | 新規ベンゾピラン誘導体 |
JP55182854A JPS57106619A (en) | 1980-12-25 | 1980-12-25 | Remedy for circulatory disease |
JP18285480 | 1980-12-25 |
Publications (3)
Publication Number | Publication Date |
---|---|
DK264181A true DK264181A (da) | 1981-12-18 |
DK154557B DK154557B (da) | 1988-11-28 |
DK154557C DK154557C (da) | 1989-04-17 |
Family
ID=26421809
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK264181A DK154557C (da) | 1980-06-17 | 1981-06-16 | Analogifremgangsmaade til fremstilling af 3,4-dihydro-8-((2-hydroxy-3-alkylamino)-propoxy)-2h-1-benzopyranderivater eller et farmaceutisk acceptabelt syreadditionssalt deraf |
Country Status (16)
Country | Link |
---|---|
US (1) | US4394382A (da) |
EP (1) | EP0042299B1 (da) |
KR (1) | KR850000193B1 (da) |
AU (1) | AU543347B2 (da) |
CA (1) | CA1178598A (da) |
CS (1) | CS226731B2 (da) |
DD (1) | DD160453A5 (da) |
DE (1) | DE3166300D1 (da) |
DK (1) | DK154557C (da) |
ES (1) | ES503091A0 (da) |
FI (1) | FI79307C (da) |
IE (1) | IE52067B1 (da) |
NO (1) | NO154495C (da) |
PL (1) | PL130537B1 (da) |
SU (1) | SU1212325A3 (da) |
ZA (1) | ZA814042B (da) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5965076A (ja) * | 1982-10-05 | 1984-04-13 | Kowa Co | 新規なキノリン誘導体 |
JPS60181083A (ja) * | 1984-02-29 | 1985-09-14 | Kowa Co | 新規ラセミ体及びその変換方法 |
JPS60208973A (ja) * | 1984-03-31 | 1985-10-21 | Kowa Co | 循環系疾患治療剤 |
GB8730051D0 (en) * | 1987-12-23 | 1988-02-03 | Beecham Group Plc | Novel compounds |
BR9708949A (pt) * | 1996-05-14 | 1999-08-03 | Glaxo Group Ltd | Composto formulação farmacêutica e processos de preparação dos mesmos e de tratamento de um mamífero incluindo o homem |
JP4000505B2 (ja) | 1999-12-01 | 2007-10-31 | 第一三共株式会社 | 緑内障を治療するための併用剤 |
MXPA05001958A (es) | 2002-08-19 | 2005-04-28 | Pfizer Prod Inc | Terapia de combinacion para enfermedades hiperproliferativas. |
JP4675232B2 (ja) * | 2002-10-24 | 2011-04-20 | 興和株式会社 | 神経線維再生促進剤 |
US20050037063A1 (en) * | 2003-07-21 | 2005-02-17 | Bolton Anthony E. | Combined therapies |
GT200600381A (es) | 2005-08-25 | 2007-03-28 | Compuestos organicos | |
US7741317B2 (en) | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
US7888376B2 (en) | 2005-11-23 | 2011-02-15 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
CN101663262B (zh) | 2006-12-01 | 2014-03-26 | 百时美施贵宝公司 | 用于治疗动脉粥样硬化和心血管疾病的作为cetp抑制剂的n-(3-苄基)-2,2-(二苯基)-丙-1胺衍生物 |
TWI646091B (zh) * | 2012-12-28 | 2019-01-01 | 日商衛斯克慧特股份有限公司 | 鹽類及晶形 |
CN105143203A (zh) | 2013-04-17 | 2015-12-09 | 辉瑞大药厂 | 用于治疗心血管疾病的n-哌啶-3-基苯甲酰胺衍生物 |
WO2016055901A1 (en) | 2014-10-08 | 2016-04-14 | Pfizer Inc. | Substituted amide compounds |
CN113574055B (zh) | 2019-01-18 | 2024-07-23 | 阿斯利康(瑞典)有限公司 | Pcsk9抑制剂及其使用方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1493998A (en) * | 1975-06-03 | 1977-12-07 | Beecham Group Ltd | Propanolamine derivatives |
JPS54106476A (en) * | 1978-01-04 | 1979-08-21 | Merck & Co Inc | Multiisubstituted 22*33lower alkylaminoo22 r100propoxy*pyridine |
DE2804625A1 (de) * | 1978-02-03 | 1979-08-09 | Thomae Gmbh Dr K | Neue 4-acylamino-phenyl-aethanolamine |
DE2805404A1 (de) * | 1978-02-09 | 1979-08-16 | Merck Patent Gmbh | 1-aryloxy-3-nitratoalkylamino-2-propanole und verfahren zu ihrer herstellung |
-
1981
- 1981-06-09 US US06/271,927 patent/US4394382A/en not_active Expired - Lifetime
- 1981-06-11 AU AU71652/81A patent/AU543347B2/en not_active Expired
- 1981-06-12 CA CA000379656A patent/CA1178598A/en not_active Expired
- 1981-06-12 IE IE1312/81A patent/IE52067B1/en not_active IP Right Cessation
- 1981-06-15 FI FI811856A patent/FI79307C/fi not_active IP Right Cessation
- 1981-06-16 ZA ZA814042A patent/ZA814042B/xx unknown
- 1981-06-16 ES ES503091A patent/ES503091A0/es active Granted
- 1981-06-16 DK DK264181A patent/DK154557C/da not_active IP Right Cessation
- 1981-06-16 CS CS814509A patent/CS226731B2/cs unknown
- 1981-06-16 NO NO812042A patent/NO154495C/no not_active IP Right Cessation
- 1981-06-16 KR KR1019810002196A patent/KR850000193B1/ko active
- 1981-06-16 EP EP81302700A patent/EP0042299B1/en not_active Expired
- 1981-06-16 DE DE8181302700T patent/DE3166300D1/de not_active Expired
- 1981-06-16 SU SU813300799A patent/SU1212325A3/ru active
- 1981-06-17 DD DD81230894A patent/DD160453A5/de not_active IP Right Cessation
- 1981-06-17 PL PL1981231734A patent/PL130537B1/pl unknown
Also Published As
Publication number | Publication date |
---|---|
AU543347B2 (en) | 1985-04-18 |
CA1178598A (en) | 1984-11-27 |
ES8300104A1 (es) | 1982-10-01 |
DD160453A5 (de) | 1983-08-03 |
IE811312L (en) | 1981-12-17 |
US4394382A (en) | 1983-07-19 |
FI79307C (fi) | 1989-12-11 |
DE3166300D1 (en) | 1984-10-31 |
PL231734A1 (da) | 1982-08-16 |
ES503091A0 (es) | 1982-10-01 |
NO812042L (no) | 1981-12-18 |
KR830006268A (ko) | 1983-09-20 |
DK154557C (da) | 1989-04-17 |
ZA814042B (en) | 1982-06-30 |
SU1212325A3 (ru) | 1986-02-15 |
PL130537B1 (en) | 1984-08-31 |
NO154495C (no) | 1986-10-01 |
CS226731B2 (en) | 1984-04-16 |
FI79307B (fi) | 1989-08-31 |
KR850000193B1 (ko) | 1985-03-05 |
FI811856L (fi) | 1981-12-18 |
EP0042299B1 (en) | 1984-09-26 |
AU7165281A (en) | 1981-12-24 |
DK154557B (da) | 1988-11-28 |
NO154495B (no) | 1986-06-23 |
IE52067B1 (en) | 1987-06-10 |
EP0042299A1 (en) | 1981-12-23 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO814112L (no) | 1-sulfo-2-oksoazetidinderivater og fremgangsmaate for deres fremstilling | |
DK319480A (da) | Muramylpeptidforbindelser samt deres fremstilling og anvendelse | |
DK109584D0 (da) | Acrylsyreamider,deres fremstilling og anvendelse | |
DK264181A (da) | Benzopyranforbindelser og syreadditionssalte deraf deres fremstilling og anvendelse | |
DK155583D0 (da) | Hydantoiner, deres fremstilling og anvendelse | |
DK363080A (da) | Clavulansyresalte og anvendelse deraf | |
DK168579A (da) | Corticoid-21-halogen-17-alkylcarbonater deres fremstilling og anvendelse | |
DK457781A (da) | Bicyclooxyhenylurinstoffer deres fremstilling og anvendelse | |
DK379481A (da) | Phosphotsyremonoestersalte deres fremstilling og anvendelse som fungicider | |
DK395580A (da) | Aminosyrederivater deres fremstilling og anvendelse | |
DK600183A (da) | Krystalliserede cephem-syreadditionssalte, deres fremstilling og anvendelse | |
DK323981A (da) | 4,5-diaryl-alfa-polyfluoralkyl-1h-imidazol-2-methanaminer eller syreadditionssalte deraf deres fremstilling og anvendelse som antiinflammatoriske midler | |
NO832137L (no) | Vinylkarboksylsyrederivater og deres fremstilling | |
DK527784A (da) | Cyanopyrazol-forbindelser, deres fremstilling og anvendelse i herbicider | |
NO813581L (no) | Karboksylatsalter, deres fremstilling og deres bruk i belegg | |
DK30082A (da) | Kemiske forbindelser deres fremstilling og deres anvendelse i laegemidler | |
DK35884A (da) | Lactampeptider samt deres fremstilling og anvendelse | |
DK323680A (da) | Carboxylater deres fremstilling og anvendelse isaer i insekticider | |
DK169481A (da) | Kobberphthalocyaninpigmenter deres fremstilling og deres anvendelse | |
DK294581A (da) | 1-aryl-cyclopropan-1-carboxylsyreestere fremgangsmaade til deres fremstilling og deres anvendelse i skadedyrsbekaempelsesmidler | |
DK291380A (da) | Amino-thiadiazolylforbindelser samt deres fremstilling og anvendelse | |
DK166380A (da) | 0-ethyl-s-alkyl-s-isopropylphosphorditiiolater deres fremstilling og anvendelse i nematodicer | |
DK189584D0 (da) | (5alfa)-20-spirox-1-en-3-oner samt deres fremstilling og anvendelse | |
DK522883D0 (da) | 2-heterocyclythio-alkyl-2-penem-forbindelser samt deres fremstilling og anvendelse | |
DK356481A (da) | Hetero-prostaglandinderivater og deres fremstilling |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUP | Patent expired |