DK2598479T3 - Fremgangsmåde til fremstilling af Ramipril - Google Patents
Fremgangsmåde til fremstilling af Ramipril Download PDFInfo
- Publication number
- DK2598479T3 DK2598479T3 DK11840625T DK11840625T DK2598479T3 DK 2598479 T3 DK2598479 T3 DK 2598479T3 DK 11840625 T DK11840625 T DK 11840625T DK 11840625 T DK11840625 T DK 11840625T DK 2598479 T3 DK2598479 T3 DK 2598479T3
- Authority
- DK
- Denmark
- Prior art keywords
- ramipril
- preparing
- preparing ramipril
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/16—Preparation of optical isomers
- C07C231/18—Preparation of optical isomers by stereospecific synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/16—Preparation of optical isomers
- C07C231/20—Preparation of optical isomers by separation of optical isomers
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN3094MU2010 | 2010-11-11 | ||
| PCT/IN2011/000207 WO2012063252A2 (en) | 2010-11-11 | 2011-04-05 | A method for preparing ramipril |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2598479T3 true DK2598479T3 (da) | 2015-05-04 |
Family
ID=46051350
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK11840625T DK2598479T3 (da) | 2010-11-11 | 2011-04-05 | Fremgangsmåde til fremstilling af Ramipril |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP2598479B1 (da) |
| CN (1) | CN103282350B (da) |
| CA (1) | CA2810475C (da) |
| DE (1) | DE11840625T1 (da) |
| DK (1) | DK2598479T3 (da) |
| ES (1) | ES2428439T1 (da) |
| HK (1) | HK1183024A1 (da) |
| HU (1) | HUE026124T2 (da) |
| SI (1) | SI2598479T1 (da) |
| WO (1) | WO2012063252A2 (da) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2013328352A1 (en) | 2012-10-10 | 2015-05-14 | Piramal Enterprises Limited | An improved process for preparation of Perindopril intermediate |
| CN104513292A (zh) * | 2013-09-29 | 2015-04-15 | 山东新时代药业有限公司 | 一种雷米普利的制备方法 |
| US10112973B2 (en) * | 2014-06-11 | 2018-10-30 | Sanofi-Aventis Deutschland Gmbh | Process for the preparation of ramipril |
| WO2016102967A1 (en) | 2014-12-23 | 2016-06-30 | Convergence Pharmaceuticals Limited | Process for preparing alpha-carboxamide pyrrolidine derivatives |
| CN104817486B (zh) * | 2015-03-31 | 2018-05-22 | 浙江工业大学 | 一种雷米普利中间体的合成方法 |
| WO2017155025A1 (ja) * | 2016-03-10 | 2017-09-14 | 第一三共株式会社 | 酵素による光学分割を用いた光学活性吉草酸誘導体の製造方法 |
| CN105777611A (zh) * | 2016-03-17 | 2016-07-20 | 浙江工业大学 | 一种丝氨酸制备雷米普利关键中间体的合成方法 |
| KR20200061381A (ko) * | 2017-10-05 | 2020-06-02 | 바이오젠 인크. | 알파-카르복스아미드 피롤리딘 유도체를 제조하기 위한 공정 |
| CN109721524A (zh) * | 2017-10-31 | 2019-05-07 | 鲁南制药集团股份有限公司 | 一种雷米普利的精制方法 |
| CN109836475B (zh) * | 2017-11-24 | 2021-09-14 | 鲁南制药集团股份有限公司 | 一种雷米普利杂质d转化为雷米普利的方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102005061756B4 (de) * | 2005-12-21 | 2008-01-03 | Sanofi-Aventis Deutschland Gmbh | Verbessertes Verfahren zur Herstellung von Ramipril |
| EP2200981B1 (en) * | 2007-10-17 | 2011-12-07 | DSM IP Assets B.V. | Novel carbamoylglycine derivatives |
| EP2344455A1 (en) * | 2008-10-30 | 2011-07-20 | DSM IP Assets B.V. | Method for the synthesis of a ramipril intermediate |
-
2011
- 2011-04-05 ES ES11840625T patent/ES2428439T1/es active Pending
- 2011-04-05 WO PCT/IN2011/000207 patent/WO2012063252A2/en active Application Filing
- 2011-04-05 HU HUE11840625A patent/HUE026124T2/en unknown
- 2011-04-05 CN CN201180064168.3A patent/CN103282350B/zh active Active
- 2011-04-05 DE DE11840625T patent/DE11840625T1/de active Pending
- 2011-04-05 CA CA2810475A patent/CA2810475C/en active Active
- 2011-04-05 DK DK11840625T patent/DK2598479T3/da active
- 2011-04-05 SI SI201130503T patent/SI2598479T1/sl unknown
- 2011-04-05 EP EP11840625.5A patent/EP2598479B1/en active Active
-
2013
- 2013-09-06 HK HK13110376.8A patent/HK1183024A1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2428439T1 (es) | 2013-11-07 |
| DE11840625T1 (de) | 2013-11-28 |
| HK1183024A1 (en) | 2013-12-13 |
| CN103282350B (zh) | 2015-02-04 |
| CA2810475A1 (en) | 2012-05-18 |
| CA2810475C (en) | 2016-09-13 |
| SI2598479T1 (sl) | 2015-06-30 |
| WO2012063252A3 (en) | 2012-10-04 |
| WO2012063252A2 (en) | 2012-05-18 |
| HUE026124T2 (en) | 2016-05-30 |
| EP2598479B1 (en) | 2015-04-01 |
| EP2598479A2 (en) | 2013-06-05 |
| CN103282350A (zh) | 2013-09-04 |
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