DK2742017T3 - Fremgangsmåde til fremstilling af komplekser af 68ga - Google Patents

Fremgangsmåde til fremstilling af komplekser af 68ga Download PDF

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Publication number
DK2742017T3
DK2742017T3 DK12756391.4T DK12756391T DK2742017T3 DK 2742017 T3 DK2742017 T3 DK 2742017T3 DK 12756391 T DK12756391 T DK 12756391T DK 2742017 T3 DK2742017 T3 DK 2742017T3
Authority
DK
Denmark
Prior art keywords
complexs
preparing
procedure
Prior art date
Application number
DK12756391.4T
Other languages
English (en)
Inventor
Lorenza Fugazza
Maria Azzurra Filannino
Maurizio Franco Mariani
Original Assignee
Advanced Accelerator Applic S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Advanced Accelerator Applic S A filed Critical Advanced Accelerator Applic S A
Application granted granted Critical
Publication of DK2742017T3 publication Critical patent/DK2742017T3/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0474Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0482Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/008Peptides; Proteins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK12756391.4T 2011-08-12 2012-08-10 Fremgangsmåde til fremstilling af komplekser af 68ga DK2742017T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000180A ITFI20110180A1 (it) 2011-08-12 2011-08-12 Processo per la preparazione di complessi di 68ga.
PCT/EP2012/065659 WO2013024013A2 (en) 2011-08-12 2012-08-10 Process for the preparation of complexes of 68ga.

Publications (1)

Publication Number Publication Date
DK2742017T3 true DK2742017T3 (da) 2016-02-08

Family

ID=44898621

Family Applications (1)

Application Number Title Priority Date Filing Date
DK12756391.4T DK2742017T3 (da) 2011-08-12 2012-08-10 Fremgangsmåde til fremstilling af komplekser af 68ga

Country Status (19)

Country Link
US (2) US9375498B2 (da)
EP (3) EP2742017B1 (da)
JP (1) JP6161610B2 (da)
CN (1) CN103889930B (da)
AU (1) AU2012297008B2 (da)
BR (2) BR112014003336B1 (da)
CA (2) CA3045484C (da)
CO (1) CO7020857A2 (da)
DK (1) DK2742017T3 (da)
ES (2) ES2835581T3 (da)
IL (3) IL230904B (da)
IN (1) IN2014CN01897A (da)
IT (1) ITFI20110180A1 (da)
MX (1) MX370081B (da)
PL (1) PL2742017T3 (da)
PT (1) PT2742017E (da)
RU (2) RU2605090C2 (da)
WO (1) WO2013024013A2 (da)
ZA (1) ZA201401789B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11027030B2 (en) 2014-08-29 2021-06-08 Anmi S.A. Kit for radiolabelling
BE1021191B1 (fr) 2014-08-29 2015-10-27 Anmi S.A. Kit pour radiomarquage.
CA2974415C (en) * 2015-01-30 2023-07-04 Lorenza Fugazza Process for the purification of ga-68 from eluate deriving from 68ge/68ga generators and chromatographic columns for use in said process
GB201504064D0 (en) 2015-03-10 2015-04-22 Accretion Biotechnology Ltd Method and kits for preparing radionuclide complexes
AU2021262479A1 (en) * 2020-04-29 2022-11-17 Novartis Ag Methods for radiolabelling PSMA binding ligands and their kits
RU2760273C1 (ru) * 2020-11-02 2021-11-23 Федеральное государственное бюджетное учреждение науки Ордена Трудового Красного Знамени Институт химии силикатов им. И.В. Гребенщикова Российской академии наук (ИХС РАН) Способ получения комплексов на основе изотопа галлий-68
CN117500772A (zh) 2021-05-31 2024-02-02 泰利克斯制药(创新)私人有限公司 改进的前列腺特异性膜抗原靶向放射性药物及其用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6056939A (en) * 1998-08-28 2000-05-02 Desreux; Jean F. Self-assembling heteropolymetallic chelates as imaging agents and radiopharmaceuticals
WO2003048207A2 (en) * 2001-11-28 2003-06-12 Immunomedics, Inc. Anti-dota antibody
GB0308408D0 (en) * 2003-04-11 2003-05-21 Amersham Plc Microwave activation
CA2783275A1 (en) * 2003-07-24 2005-02-03 Bracco Imaging S.P.A. Stable radiopharmaceutical compositions and methods for their preparation
CN1874792A (zh) * 2003-09-03 2006-12-06 布里斯托尔-迈尔斯.斯奎布制药公司 包含基质金属蛋白酶底物的化合物及其使用方法
DE102004057225B4 (de) * 2004-11-26 2006-10-12 Johannes-Gutenberg-Universität Mainz Verfahren und Vorrichtung zur Isolierung eines chemisch und radiochemisch gereinigten 68Ga-Radionuklids und zum Markieren eines Markierungsvorläufers mit dem 68Ga-Radionuklid
EP2056886A2 (en) * 2006-08-28 2009-05-13 GE Healthcare Limited 68ga-labeled peptide-based radiopharmaceuticals
FR2942227B1 (fr) * 2009-02-13 2011-04-15 Guerbet Sa Utilisation de tampons pour la complexation de radionucleides
WO2010141833A2 (en) * 2009-06-05 2010-12-09 The General Hospital Corporation Vital fluorochrome conjugates and methods of use

Also Published As

Publication number Publication date
US20140171637A1 (en) 2014-06-19
RU2605090C2 (ru) 2016-12-20
IL275979A (en) 2020-08-31
IL230904B (en) 2019-01-31
ES2560231T3 (es) 2016-02-18
EP2955168B1 (en) 2020-09-23
US20160263259A1 (en) 2016-09-15
PL2742017T3 (pl) 2016-04-29
IL230904A0 (en) 2014-03-31
EP2955168A1 (en) 2015-12-16
MX2014001691A (es) 2014-11-13
IN2014CN01897A (da) 2015-05-29
RU2014109381A (ru) 2015-09-20
EP2742017B1 (en) 2015-10-28
NZ708281A (en) 2016-01-29
CA2844145A1 (en) 2013-02-21
ES2835581T3 (es) 2021-06-22
IL275979B2 (en) 2023-02-01
US9907868B2 (en) 2018-03-06
CA2844145C (en) 2019-07-30
PT2742017E (pt) 2016-02-26
BR122020011908B1 (pt) 2022-07-05
AU2012297008B2 (en) 2016-12-08
AU2012297008A1 (en) 2014-03-20
EP2742017A2 (en) 2014-06-18
WO2013024013A3 (en) 2013-05-02
IL275979B (en) 2022-10-01
IL245849B (en) 2021-03-25
CN103889930A (zh) 2014-06-25
ITFI20110180A1 (it) 2013-02-13
CN103889930B (zh) 2017-03-29
RU2020120802A (ru) 2021-12-23
IL245849A0 (en) 2016-07-31
EP3718991A1 (en) 2020-10-07
BR112014003336B1 (pt) 2021-03-09
ZA201401789B (en) 2015-01-28
CA3045484C (en) 2022-10-11
JP6161610B2 (ja) 2017-07-12
US9375498B2 (en) 2016-06-28
BR112014003336A2 (pt) 2017-03-14
WO2013024013A2 (en) 2013-02-21
CA3045484A1 (en) 2013-02-21
RU2016144237A3 (da) 2019-10-10
NZ622071A (en) 2015-07-31
RU2016144237A (ru) 2018-12-18
MX370081B (es) 2019-11-29
JP2014524423A (ja) 2014-09-22
CO7020857A2 (es) 2014-08-11

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