DK2571887T3 - Fremgangsmåde til fremstilling af dithiin-tetracarboxy-diimider - Google Patents
Fremgangsmåde til fremstilling af dithiin-tetracarboxy-diimider Download PDFInfo
- Publication number
- DK2571887T3 DK2571887T3 DK11719280.7T DK11719280T DK2571887T3 DK 2571887 T3 DK2571887 T3 DK 2571887T3 DK 11719280 T DK11719280 T DK 11719280T DK 2571887 T3 DK2571887 T3 DK 2571887T3
- Authority
- DK
- Denmark
- Prior art keywords
- sulphide
- alkyl
- hydrogen
- halogen
- formula
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims description 21
- 238000002360 preparation method Methods 0.000 title claims description 7
- 150000001875 compounds Chemical class 0.000 claims description 21
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 21
- 239000000203 mixture Substances 0.000 claims description 18
- RWSOTUBLDIXVET-UHFFFAOYSA-N Dihydrogen sulfide Chemical compound S RWSOTUBLDIXVET-UHFFFAOYSA-N 0.000 claims description 17
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 claims description 15
- UCKMPCXJQFINFW-UHFFFAOYSA-N Sulphide Chemical compound [S-2] UCKMPCXJQFINFW-UHFFFAOYSA-N 0.000 claims description 13
- 229910052739 hydrogen Inorganic materials 0.000 claims description 13
- 239000001257 hydrogen Substances 0.000 claims description 13
- 150000002431 hydrogen Chemical class 0.000 claims description 13
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims description 12
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 claims description 12
- 229910052736 halogen Inorganic materials 0.000 claims description 12
- 150000002367 halogens Chemical class 0.000 claims description 12
- 239000003085 diluting agent Substances 0.000 claims description 11
- -1 dichloromaleic acid imides Chemical class 0.000 claims description 10
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 claims description 9
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 claims description 8
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 claims description 7
- 125000003118 aryl group Chemical group 0.000 claims description 7
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 7
- 229920000642 polymer Polymers 0.000 claims description 7
- ZHNUHDYFZUAESO-UHFFFAOYSA-N Formamide Chemical compound NC=O ZHNUHDYFZUAESO-UHFFFAOYSA-N 0.000 claims description 6
- ZGSDJMADBJCNPN-UHFFFAOYSA-N [S-][NH3+] Chemical compound [S-][NH3+] ZGSDJMADBJCNPN-UHFFFAOYSA-N 0.000 claims description 6
- KXKVLQRXCPHEJC-UHFFFAOYSA-N methyl acetate Chemical compound COC(C)=O KXKVLQRXCPHEJC-UHFFFAOYSA-N 0.000 claims description 6
- 239000002904 solvent Substances 0.000 claims description 6
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 claims description 5
- GRVFOGOEDUUMBP-UHFFFAOYSA-N sodium sulfide (anhydrous) Chemical compound [Na+].[Na+].[S-2] GRVFOGOEDUUMBP-UHFFFAOYSA-N 0.000 claims description 5
- NTIZESTWPVYFNL-UHFFFAOYSA-N Methyl isobutyl ketone Chemical compound CC(C)CC(C)=O NTIZESTWPVYFNL-UHFFFAOYSA-N 0.000 claims description 4
- UIHCLUNTQKBZGK-UHFFFAOYSA-N Methyl isobutyl ketone Natural products CCC(C)C(C)=O UIHCLUNTQKBZGK-UHFFFAOYSA-N 0.000 claims description 4
- FXHOOIRPVKKKFG-UHFFFAOYSA-N N,N-Dimethylacetamide Chemical compound CN(C)C(C)=O FXHOOIRPVKKKFG-UHFFFAOYSA-N 0.000 claims description 4
- AMQJEAYHLZJPGS-UHFFFAOYSA-N N-Pentanol Chemical compound CCCCCO AMQJEAYHLZJPGS-UHFFFAOYSA-N 0.000 claims description 4
- KVNRLNFWIYMESJ-UHFFFAOYSA-N butyronitrile Chemical compound CCCC#N KVNRLNFWIYMESJ-UHFFFAOYSA-N 0.000 claims description 4
- ZXEKIIBDNHEJCQ-UHFFFAOYSA-N isobutanol Chemical compound CC(C)CO ZXEKIIBDNHEJCQ-UHFFFAOYSA-N 0.000 claims description 4
- SECXISVLQFMRJM-UHFFFAOYSA-N N-Methylpyrrolidone Chemical compound CN1CCCC1=O SECXISVLQFMRJM-UHFFFAOYSA-N 0.000 claims description 3
- 150000001298 alcohols Chemical class 0.000 claims description 3
- 150000001408 amides Chemical class 0.000 claims description 3
- 239000007795 chemical reaction product Substances 0.000 claims description 3
- 150000002148 esters Chemical class 0.000 claims description 3
- 150000002576 ketones Chemical class 0.000 claims description 3
- 150000002825 nitriles Chemical class 0.000 claims description 3
- PJGSXYOJTGTZAV-UHFFFAOYSA-N pinacolone Chemical compound CC(=O)C(C)(C)C PJGSXYOJTGTZAV-UHFFFAOYSA-N 0.000 claims description 3
- DPLVEEXVKBWGHE-UHFFFAOYSA-N potassium sulfide Chemical compound [S-2].[K+].[K+] DPLVEEXVKBWGHE-UHFFFAOYSA-N 0.000 claims description 3
- 239000011877 solvent mixture Substances 0.000 claims description 3
- HXJUTPCZVOIRIF-UHFFFAOYSA-N sulfolane Chemical compound O=S1(=O)CCCC1 HXJUTPCZVOIRIF-UHFFFAOYSA-N 0.000 claims description 3
- DKPFZGUDAPQIHT-UHFFFAOYSA-N Butyl acetate Natural products CCCCOC(C)=O DKPFZGUDAPQIHT-UHFFFAOYSA-N 0.000 claims description 2
- AGVJBLHVMNHENQ-UHFFFAOYSA-N Calcium sulfide Chemical compound [S-2].[Ca+2] AGVJBLHVMNHENQ-UHFFFAOYSA-N 0.000 claims description 2
- LBVNUQQORDPZCR-UHFFFAOYSA-N calcium;sulfane Chemical compound S.[Ca] LBVNUQQORDPZCR-UHFFFAOYSA-N 0.000 claims description 2
- 238000010438 heat treatment Methods 0.000 claims description 2
- GLNWILHOFOBOFD-UHFFFAOYSA-N lithium sulfide Chemical compound [Li+].[Li+].[S-2] GLNWILHOFOBOFD-UHFFFAOYSA-N 0.000 claims description 2
- UNHKSXOTUHOTAB-UHFFFAOYSA-N sodium;sulfane Chemical compound [Na].S UNHKSXOTUHOTAB-UHFFFAOYSA-N 0.000 claims description 2
- SMDQFHZIWNYSMR-UHFFFAOYSA-N sulfanylidenemagnesium Chemical compound S=[Mg] SMDQFHZIWNYSMR-UHFFFAOYSA-N 0.000 claims description 2
- 125000004765 (C1-C4) haloalkyl group Chemical group 0.000 claims 5
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 claims 2
- 229910000037 hydrogen sulfide Inorganic materials 0.000 claims 2
- 125000006296 sulfonyl amino group Chemical group [H]N(*)S(*)(=O)=O 0.000 claims 2
- 125000004448 alkyl carbonyl group Chemical group 0.000 claims 1
- 125000000753 cycloalkyl group Chemical group 0.000 claims 1
- FUZZWVXGSFPDMH-UHFFFAOYSA-M hexanoate Chemical compound CCCCCC([O-])=O FUZZWVXGSFPDMH-UHFFFAOYSA-M 0.000 claims 1
- 229910052945 inorganic sulfide Inorganic materials 0.000 claims 1
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 63
- 239000007787 solid Substances 0.000 description 20
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 16
- 239000000460 chlorine Substances 0.000 description 12
- 229910052801 chlorine Inorganic materials 0.000 description 12
- KVBAKSQRUXXHCK-UHFFFAOYSA-N 3,4-Dichloro-5-hydroxy-2H-pyrrol-2-one Chemical class ClC1=C(Cl)C(=O)NC1=O KVBAKSQRUXXHCK-UHFFFAOYSA-N 0.000 description 11
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 11
- 239000000047 product Substances 0.000 description 9
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 8
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 8
- 238000004128 high performance liquid chromatography Methods 0.000 description 8
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 description 8
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 description 7
- 229910052731 fluorine Inorganic materials 0.000 description 7
- 239000011737 fluorine Substances 0.000 description 7
- ZWEHNKRNPOVVGH-UHFFFAOYSA-N 2-Butanone Chemical compound CCC(C)=O ZWEHNKRNPOVVGH-UHFFFAOYSA-N 0.000 description 6
- PYOLPWAVSYVLMM-UHFFFAOYSA-N 3,4-dichloro-1-methylpyrrole-2,5-dione Chemical compound CN1C(=O)C(Cl)=C(Cl)C1=O PYOLPWAVSYVLMM-UHFFFAOYSA-N 0.000 description 6
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 6
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 description 6
- 238000006243 chemical reaction Methods 0.000 description 6
- 229960001760 dimethyl sulfoxide Drugs 0.000 description 5
- TWKKUWBBCHHMLT-UHFFFAOYSA-N disodium;sulfide;trihydrate Chemical compound O.O.O.[Na+].[Na+].[S-2] TWKKUWBBCHHMLT-UHFFFAOYSA-N 0.000 description 5
- 239000011541 reaction mixture Substances 0.000 description 5
- RYHBNJHYFVUHQT-UHFFFAOYSA-N 1,4-Dioxane Chemical compound C1COCCO1 RYHBNJHYFVUHQT-UHFFFAOYSA-N 0.000 description 4
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 description 4
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 description 4
- XBDQKXXYIPTUBI-UHFFFAOYSA-M Propionate Chemical compound CCC([O-])=O XBDQKXXYIPTUBI-UHFFFAOYSA-M 0.000 description 4
- DKGAVHZHDRPRBM-UHFFFAOYSA-N Tert-Butanol Chemical compound CC(C)(C)O DKGAVHZHDRPRBM-UHFFFAOYSA-N 0.000 description 4
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 description 4
- 229910052794 bromium Inorganic materials 0.000 description 4
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 4
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 4
- 239000012925 reference material Substances 0.000 description 4
- FYSNRJHAOHDILO-UHFFFAOYSA-N thionyl chloride Chemical compound ClS(Cl)=O FYSNRJHAOHDILO-UHFFFAOYSA-N 0.000 description 4
- UMGDCJDMYOKAJW-UHFFFAOYSA-N thiourea Chemical compound NC(N)=S UMGDCJDMYOKAJW-UHFFFAOYSA-N 0.000 description 4
- JFDZBHWFFUWGJE-UHFFFAOYSA-N benzonitrile Chemical compound N#CC1=CC=CC=C1 JFDZBHWFFUWGJE-UHFFFAOYSA-N 0.000 description 3
- 238000001914 filtration Methods 0.000 description 3
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 description 3
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 3
- 239000004133 Sodium thiosulphate Substances 0.000 description 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Natural products NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 2
- 150000001412 amines Chemical class 0.000 description 2
- 230000000052 comparative effect Effects 0.000 description 2
- HPXRVTGHNJAIIH-UHFFFAOYSA-N cyclohexanol Chemical compound OC1CCCCC1 HPXRVTGHNJAIIH-UHFFFAOYSA-N 0.000 description 2
- 125000001301 ethoxy group Chemical group [H]C([H])([H])C([H])([H])O* 0.000 description 2
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 2
- 238000001819 mass spectrum Methods 0.000 description 2
- 125000004674 methylcarbonyl group Chemical group CC(=O)* 0.000 description 2
- 125000004123 n-propyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])* 0.000 description 2
- 230000035484 reaction time Effects 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- AKHNMLFCWUSKQB-UHFFFAOYSA-L sodium thiosulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=S AKHNMLFCWUSKQB-UHFFFAOYSA-L 0.000 description 2
- 235000019345 sodium thiosulphate Nutrition 0.000 description 2
- 239000007858 starting material Substances 0.000 description 2
- 125000004206 2,2,2-trifluoroethyl group Chemical group [H]C([H])(*)C(F)(F)F 0.000 description 1
- 125000004778 2,2-difluoroethyl group Chemical group [H]C([H])(*)C([H])(F)F 0.000 description 1
- FALRKNHUBBKYCC-UHFFFAOYSA-N 2-(chloromethyl)pyridine-3-carbonitrile Chemical compound ClCC1=NC=CC=C1C#N FALRKNHUBBKYCC-UHFFFAOYSA-N 0.000 description 1
- XNWFRZJHXBZDAG-UHFFFAOYSA-N 2-METHOXYETHANOL Chemical compound COCCO XNWFRZJHXBZDAG-UHFFFAOYSA-N 0.000 description 1
- AGULWIQIYWWFBJ-UHFFFAOYSA-N 3,4-dichlorofuran-2,5-dione Chemical compound ClC1=C(Cl)C(=O)OC1=O AGULWIQIYWWFBJ-UHFFFAOYSA-N 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 208000031888 Mycoses Diseases 0.000 description 1
- 241000244206 Nematoda Species 0.000 description 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 1
- 239000005864 Sulphur Substances 0.000 description 1
- 230000000507 anthelmentic effect Effects 0.000 description 1
- 229940124339 anthelmintic agent Drugs 0.000 description 1
- 239000000921 anthelmintic agent Substances 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 description 1
- 239000006227 byproduct Substances 0.000 description 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 1
- 125000001309 chloro group Chemical group Cl* 0.000 description 1
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 description 1
- XCIXKGXIYUWCLL-UHFFFAOYSA-N cyclopentanol Chemical compound OC1CCCC1 XCIXKGXIYUWCLL-UHFFFAOYSA-N 0.000 description 1
- 125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 description 1
- 230000006735 deficit Effects 0.000 description 1
- 239000000975 dye Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 150000002170 ethers Chemical class 0.000 description 1
- 125000004672 ethylcarbonyl group Chemical group [H]C([H])([H])C([H])([H])C(*)=O 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 239000000417 fungicide Substances 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- FUZZWVXGSFPDMH-UHFFFAOYSA-N hexanoic acid Chemical compound CCCCCC(O)=O FUZZWVXGSFPDMH-UHFFFAOYSA-N 0.000 description 1
- 150000004677 hydrates Chemical class 0.000 description 1
- 230000000749 insecticidal effect Effects 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000003973 paint Substances 0.000 description 1
- 244000045947 parasite Species 0.000 description 1
- 108091008695 photoreceptors Proteins 0.000 description 1
- 230000003032 phytopathogenic effect Effects 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 239000002798 polar solvent Substances 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 238000002953 preparative HPLC Methods 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- FVSKHRXBFJPNKK-UHFFFAOYSA-N propionitrile Chemical compound CCC#N FVSKHRXBFJPNKK-UHFFFAOYSA-N 0.000 description 1
- 150000003254 radicals Chemical class 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
- JDVPQXZIJDEHAN-UHFFFAOYSA-N succinamic acid Chemical class NC(=O)CCC(O)=O JDVPQXZIJDEHAN-UHFFFAOYSA-N 0.000 description 1
- 229940014800 succinic anhydride Drugs 0.000 description 1
- 150000004763 sulfides Chemical class 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 238000010626 work up procedure Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/44—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members
- C07D207/444—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5
- C07D207/456—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5 with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
- A01N43/24—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with two or more hetero atoms
- A01N43/32—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with two or more hetero atoms six-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Environmental Sciences (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Zoology (AREA)
- Pest Control & Pesticides (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrrole Compounds (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Indole Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Claims (4)
1. Fremgangsmåde til fremstilling af dithiin-tetracarboxy- diimider med den almene formel (I)
<D hvor R1 og R2 er ens eller forskellige og står for hydrogen, for Ci-Cs-alkyl, i givet fald substitueret en eller flere gange med halogen, -OR3, -COR4, for C3-C7-cycloalkyl, i givet fald substitueret en eller flere gange med halogen, Ci-C4_alkyl eller Ci-C4-halogenalkyl, for aryl eller aryl- (Ci-C4-alkyl) , hver især i givet fald substitueret en eller flere gange med halogen, Ci-C4-alkyl, Ci-C^-halogenalkyl, -COR4 eller sulfony1amino, R3 står for hydrogen, Ci-C4-alkyl, Ci-C4-alkylcarbonyl eller for aryl, i givet fald substitueret en eller flere gange med halogen, Ci-C4-akyl eller Ci-C4-halogenalkyl, R4 står for hydroxy, Ci-C4-alkyl eller Ci-C4~alkoxy, kendetegnet ved, at man omsætter (A) dichlormaleinsyreimider med formel (VI)
(VI) hvor R står for R1 eller R2, med et uorganisk sulfid eller hydrogensulfid i et opløsningsmiddel eller en opløsningsmiddelblanding i et molforhold mellem 0,2 og 0,95 mol af sulfid eller hydrogensulfid pr. mol dichlormaleinsyreimid med formel (VI) og opvarmer (B) reaktionsproduktet, som består af en blanding af forbindelser med formel (I) og polymere forbindelser med den almene formel (VII),
<VIT) hvor R uafhængigt af hinanden står for R1 eller R2, n står for et helt tal mellem 1 og 50, i et fortyndingsmiddel.
2. Fremgangsmåde ifølge krav 1, kendetegnet ved, at sulfidet eller hydrogensulfidet er udvalgt af gruppen bestående af lithiumsulfid, natriumsulfid, natriumhydrogensulfid, kaliumsulfid, calciumsulfid, calciumhydrogensulfid, magnesiumsulfid eller ammoniumsulfid eller blandinger af disse eller hydrater af disse.
3. Fremgangsmåde ifølge krav 1, kendetegnet ved, at opløsningsmidlet anvendes fra gruppen af amider, såsom formamid, N,N-dimethyl-formamid, N,N-dimethyl-acetamid, N-methyl-pyrrolidon; alkoholer såsom propanol, isobutanol, pentanol, ethylenglykol; estere såsom eddikesyremethylester, eddikesyreethylester, butylacetat; nitriler såsom acetonitril, butyronitril; ketoner såsom pinakolon, methyl-isobutylketon; dimethylsulfoxid eller sulfolan eller vand eller blandinger af disse.
4. Polymere forbindelser med formel (VII)
(Vil) hvor R uafhængigt af hinanden står for R1 eller R2, R1 og R2 er ens eller forskellige og står for hydrogen, for Ci-Cs-alkyl, i givet fald substitueret en eller flere gange med halogen, -OR3, -COR4, for C3-C7-cycloalkyl, i givet fald substitueret en eller flere gange med halogen, Ci-C4-akyl eller Ci-C4~halogenalkyl, for aryl eller aryl-(Ci-C4-alkyl), hver især i givet fald substitueret en eller flere gange med halogen, Ci-C^-alkyl, Ci-C^-halogenalkyl, -COR4 eller sulfonylamino, R3 står for hydrogen, Ci-C4-alkyl, Ci-C4-alkylcarbonyl eller for aryl, i givet fald substitueret en eller flere gange med halogen, Ci-C4-alkyl eller Ci-C4-halogenalkyl, R4 står for hydroxy, Ci-C4-alkyl eller Ci-C4-alkoxy, n står for et helt tal mellem 1 og 50.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10163519 | 2010-05-21 | ||
| US34835510P | 2010-05-26 | 2010-05-26 | |
| PCT/EP2011/057829 WO2011144550A1 (de) | 2010-05-21 | 2011-05-16 | Verfahren zur herstellung von dithiin-tetracarboxy-diimiden |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2571887T3 true DK2571887T3 (da) | 2014-11-24 |
Family
ID=42634835
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK11719280.7T DK2571887T3 (da) | 2010-05-21 | 2011-05-16 | Fremgangsmåde til fremstilling af dithiin-tetracarboxy-diimider |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8729275B2 (da) |
| EP (1) | EP2571887B1 (da) |
| JP (1) | JP5816268B2 (da) |
| KR (1) | KR20130112719A (da) |
| CN (1) | CN102939294B (da) |
| BR (1) | BR112012029626A2 (da) |
| DK (1) | DK2571887T3 (da) |
| ES (1) | ES2518118T3 (da) |
| IL (1) | IL223145A (da) |
| MX (1) | MX2012013539A (da) |
| PL (1) | PL2571887T3 (da) |
| RU (1) | RU2574393C9 (da) |
| WO (1) | WO2011144550A1 (da) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2559626C9 (ru) | 2010-04-14 | 2016-05-27 | Байер Интеллектуэль Проперти Гмбх | Способ получения дитиин-тетракарбоксимидов |
| ES2516141T3 (es) * | 2010-04-14 | 2014-10-30 | Bayer Cropscience Ag | Procedimiento para la preparación de ditiina-tetracarboxi-diimidas |
| WO2012028588A1 (de) | 2010-09-03 | 2012-03-08 | Bayer Cropscience Ag | Verfahren zur herstellung von dithiin-tetracarboximiden |
| EP2641908A1 (de) * | 2012-03-23 | 2013-09-25 | Bayer CropScience AG | Verfahren zur Herstellung von Dithiin-tetracarboximiden |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3364229A (en) * | 1964-01-30 | 1968-01-16 | Shell Oil Co | 1, 4 dithiin-2, 3, 5, 6-tetracarboximides and process for their preparation |
| SU649292A3 (ru) * | 1974-05-22 | 1979-02-25 | Юниройял Инк | Состав дл регулировани роста растений |
| US4067879A (en) * | 1975-10-23 | 1978-01-10 | E. I. Du Pont De Nemours And Company | 1,4-Dithiino[2,3-c; 6,5-c']diisothiazole and related compounds |
| CA1150284A (en) * | 1980-12-02 | 1983-07-19 | Allan K.S. Tsai | Method of making certain 2,3-dihydro-1,4-dithiins |
| PL143804B2 (en) | 1985-10-15 | 1988-03-31 | Univ Lodzki | Process for preparing novel derivatives of 2,6-diphenyl-2,3,6,7-tetrahydro-1h,5h-1,4-dithiin-/2,3-c:5,6-c/-diprolo-1,3,5,7-tetraon substituted in phenyl ring |
| JP3530702B2 (ja) | 1997-03-06 | 2004-05-24 | 京セラミタ株式会社 | ジチオマレイン酸イミド誘導体を用いた電子写真感光体 |
| CN100554251C (zh) * | 2005-07-12 | 2009-10-28 | 中国科学院化学研究所 | 一种马来酰亚胺衍生物及其制备方法 |
| NZ592226A (en) | 2008-10-15 | 2012-12-21 | Bayer Cropscience Ag | Use of dithiin tetracarboximides for treating phytopathogenic fungi for protecting plants |
-
2011
- 2011-05-16 PL PL11719280T patent/PL2571887T3/pl unknown
- 2011-05-16 KR KR1020127033251A patent/KR20130112719A/ko not_active Application Discontinuation
- 2011-05-16 BR BR112012029626A patent/BR112012029626A2/pt not_active Application Discontinuation
- 2011-05-16 MX MX2012013539A patent/MX2012013539A/es active IP Right Grant
- 2011-05-16 RU RU2012155464/04A patent/RU2574393C9/ru not_active IP Right Cessation
- 2011-05-16 EP EP11719280.7A patent/EP2571887B1/de not_active Not-in-force
- 2011-05-16 DK DK11719280.7T patent/DK2571887T3/da active
- 2011-05-16 CN CN201180030514.6A patent/CN102939294B/zh not_active Expired - Fee Related
- 2011-05-16 ES ES11719280.7T patent/ES2518118T3/es active Active
- 2011-05-16 WO PCT/EP2011/057829 patent/WO2011144550A1/de active Application Filing
- 2011-05-16 JP JP2013510576A patent/JP5816268B2/ja not_active Expired - Fee Related
- 2011-05-20 US US13/112,680 patent/US8729275B2/en not_active Expired - Fee Related
-
2012
- 2012-11-20 IL IL223145A patent/IL223145A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| BR112012029626A2 (pt) | 2015-10-13 |
| KR20130112719A (ko) | 2013-10-14 |
| PL2571887T3 (pl) | 2015-01-30 |
| IL223145A0 (en) | 2013-02-03 |
| WO2011144550A1 (de) | 2011-11-24 |
| JP5816268B2 (ja) | 2015-11-18 |
| ES2518118T3 (es) | 2014-11-04 |
| IL223145A (en) | 2016-05-31 |
| JP2013527180A (ja) | 2013-06-27 |
| CN102939294A (zh) | 2013-02-20 |
| CN102939294B (zh) | 2015-09-02 |
| EP2571887B1 (de) | 2014-08-20 |
| US20120022270A1 (en) | 2012-01-26 |
| MX2012013539A (es) | 2013-01-24 |
| RU2012155464A (ru) | 2014-06-27 |
| US8729275B2 (en) | 2014-05-20 |
| EP2571887A1 (de) | 2013-03-27 |
| RU2574393C9 (ru) | 2016-10-10 |
| RU2574393C2 (ru) | 2016-02-10 |
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