DK2563167T3 - PRACTICES AND lipid TO PROMOTE DEVELOPMENT OF INTESTINAL FLORA - Google Patents
PRACTICES AND lipid TO PROMOTE DEVELOPMENT OF INTESTINAL FLORA Download PDFInfo
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- DK2563167T3 DK2563167T3 DK11721378.5T DK11721378T DK2563167T3 DK 2563167 T3 DK2563167 T3 DK 2563167T3 DK 11721378 T DK11721378 T DK 11721378T DK 2563167 T3 DK2563167 T3 DK 2563167T3
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- fat source
- fat
- infants
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CN103929980A (zh) * | 2011-11-10 | 2014-07-16 | 雀巢产品技术援助有限公司 | 含有高sn-2棕榈酸酯和低聚果糖的婴儿配方乳 |
DK2956010T4 (da) * | 2013-02-12 | 2023-01-09 | Bunge Loders Croklaan B V | Fedtsammensætning |
EP2967060A4 (en) * | 2013-03-15 | 2016-11-23 | Cedars Sinai Medical Center | METHODS OF DIAGNOSING, SELECTING AND TREATING DISEASES AND CONDITIONS CAUSED BY OR ASSOCIATED WITH METHANOGENIC BACTERIA |
WO2015058115A1 (en) * | 2013-10-17 | 2015-04-23 | University Of Georgia Research Foundation, Inc. | Structured triacylglycerols and methods for making the same |
SG10201810362SA (en) * | 2014-05-22 | 2018-12-28 | Meiji Co Ltd | Anti-allergic agent, agent for improving allergic diarrhea and pharmaceutical composition |
CN106998723A (zh) * | 2014-11-21 | 2017-08-01 | 深圳华大基因科技有限公司 | 美藤果油在调节动物肠道菌群中的用途 |
WO2016097220A1 (en) * | 2014-12-19 | 2016-06-23 | Nestec S.A. | Infant nutrition with hydrolysed protein, ionic calcium and palmitic acid |
RU2703172C2 (ru) * | 2014-12-19 | 2019-10-15 | Сосьете Де Продюи Нестле С.А. | Питание для младенцев с гидролизованным белком и пальмитиновой кислотой |
WO2016129100A1 (ja) * | 2015-02-13 | 2016-08-18 | 油化産業株式会社 | 動物腸内有用菌増加剤及びこれを用いた家畜腸内環境改善方法 |
IL237290A0 (en) * | 2015-02-17 | 2015-06-30 | Enzymotec Ltd | Oil mixtures for use in formulas |
US20180139998A1 (en) * | 2015-05-04 | 2018-05-24 | Enzymotec Ltd. | Lipid compositions for improving sleep |
AU2016282647A1 (en) * | 2015-06-23 | 2017-11-09 | Société des Produits Nestlé S.A. | Nutritional compositions and infant formulas containing oligofructose for reducing the load of pathogenic bacteria in the guts of infants and young children |
CN114647779A (zh) * | 2015-08-12 | 2022-06-21 | 爱康迪健康规划服务股份有限公司 | 信息处理装置、信息处理方法和记录介质 |
MX2018001986A (es) * | 2015-08-27 | 2018-06-19 | Nestec Sa | Composiciones nutricionales sinteticas especificas de genero, y sistemas nutricionales que las comprenden. |
WO2017032885A1 (en) * | 2015-08-27 | 2017-03-02 | Nestec S.A. | Synthetic nutritional compositions tailored for infants of specific ages, and nutritional systems comprising them |
WO2017102705A1 (en) * | 2015-12-18 | 2017-06-22 | Nestec S.A. | Nutritional compositions and infant formulas containing relatively high level of oligofructose for inducing gut microbiota patterns close to those of human milk fed infants |
CN106913563A (zh) * | 2016-01-04 | 2017-07-04 | 广东工业大学 | 多烯脂肪酸类化合物在制备抗耐药菌药物中的应用 |
AU2017231043B2 (en) * | 2016-03-10 | 2021-07-29 | Frutarom Limited | Lipid compositions and uses thereof |
CN107518382A (zh) * | 2016-06-21 | 2017-12-29 | 丰益(上海)生物技术研发中心有限公司 | 一种提升肠道的中短链酸丰度的方法 |
ES2949278T3 (es) | 2016-08-17 | 2023-09-27 | Frutarom Ltd | Mezclas de aceites y procedimientos para su preparación |
US11566238B2 (en) | 2016-12-15 | 2023-01-31 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for modulating growth of a genetically modified gut bacterial cell |
NL2019906B1 (en) * | 2017-11-14 | 2019-05-20 | Ausnutria Hyproca B V | Composition comprising a2 b-casein and a vegetable fat mixture |
CN112384212A (zh) * | 2018-05-03 | 2021-02-19 | Scf制药股份有限公司 | 多不饱和脂肪酸单甘油酯、其组合物、方法和用途 |
CN110616234B (zh) * | 2018-06-20 | 2023-12-22 | 花臣有限公司 | 一种用于生产人乳脂替代物的方法 |
TW202100019A (zh) * | 2019-03-01 | 2021-01-01 | 荷蘭商弗里斯蘭康必奶荷蘭有限公司 | 脂肪組成物及基於其之營養組成物 |
MX2023002264A (es) * | 2020-08-31 | 2023-05-23 | Aak Ab Publ | Un proceso para preparar composiciones de grasa vegetal con una cantidad aumentada de acido palmitico en la posicion sn2. |
WO2024056784A1 (en) * | 2022-09-14 | 2024-03-21 | N.V. Nutricia | Nutritional composition |
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GB2178752B (en) | 1985-07-12 | 1989-10-11 | Unilever Plc | Substitute milk fat |
US5021245A (en) | 1990-05-22 | 1991-06-04 | Abbott Laboratories | Infant formula containing a soy polysaccharide fiber source |
IL129086A0 (en) | 1999-03-22 | 2000-02-17 | Enzymotec Ltd | Surfactant-lipase complex immobilized on insoluble matrix |
EP1062873A1 (en) | 1999-12-13 | 2000-12-27 | N.V. Nutricia | Improved infant formula, protein hydrolysate for use in such an infant formula, and method for producing such a hydrolysate |
US6812199B2 (en) | 2000-04-28 | 2004-11-02 | The Procter & Gamble Company | Method for treating stained materials |
CA2530437C (en) | 2003-06-23 | 2011-11-15 | Nestec S.A. | Nutritional formula for optimal gut barrier function |
NZ544726A (en) | 2003-06-23 | 2009-05-31 | Nestec Sa | Infant or follow-on formula |
IL158554A0 (en) | 2003-10-22 | 2004-05-12 | Enzymotec Ltd | Mimetic lipids as dietary supplements |
IL158555A0 (en) * | 2003-10-22 | 2004-05-12 | Enzymotec Ltd | Human breast milk lipid mimetic as dietary supplement |
EP1634599A1 (en) | 2004-08-20 | 2006-03-15 | N.V. Nutricia | Iimmune stimulatory infant nutrition |
KR101150433B1 (ko) * | 2005-04-08 | 2012-06-01 | 주식회사 일신웰스 | 유지조성물의 제조방법 |
WO2006108824A1 (en) | 2005-04-13 | 2006-10-19 | Nestec S.A. | Infant formula with probiotics |
JP2008538915A (ja) * | 2005-04-27 | 2008-11-13 | エンジィモテック リミテッド | ヒト乳脂代用物 |
WO2007108690A1 (en) * | 2006-03-23 | 2007-09-27 | N.V. Nutricia | Preterm formula |
US20080003329A1 (en) | 2006-06-30 | 2008-01-03 | Ricardo Rueda | Enriched infant formulas |
IL184982A0 (en) * | 2007-08-01 | 2008-01-20 | Enzymotec Ltd | Edible fat composition for enhancing bone strength |
CN101896073B (zh) * | 2007-10-09 | 2013-11-20 | 酶学技术有限公司 | 用于治疗胃肠道紊乱和促进肠道发育及成熟的脂质组合物 |
US20090131523A1 (en) | 2007-10-15 | 2009-05-21 | Enzymotec Ltd. | Lipid compositions for the treatment and prevention of proliferative diseases and for the reduction of incidences of mutagenesis and carinogenesis |
EP2143340A1 (en) | 2008-07-07 | 2010-01-13 | Nestec S.A. | A nutritional composition with free amino acids and structured lipids |
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2011
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