DK2549994T3 - Anvendelse af D-fagomin som hæmmer af bakteriel vedhæftning til epiteliale celler - Google Patents

Anvendelse af D-fagomin som hæmmer af bakteriel vedhæftning til epiteliale celler Download PDF

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Publication number
DK2549994T3
DK2549994T3 DK11710197.2T DK11710197T DK2549994T3 DK 2549994 T3 DK2549994 T3 DK 2549994T3 DK 11710197 T DK11710197 T DK 11710197T DK 2549994 T3 DK2549994 T3 DK 2549994T3
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Denmark
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compound
veterinary
use according
formula
fagomine
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DK11710197.2T
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English (en)
Inventor
Segura Sergio Pumarola
Simón Josep Lluis Torres
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Bioglane S L N E
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Publication of DK2549994T3 publication Critical patent/DK2549994T3/da

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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/12—Fermented milk preparations; Treatment using microorganisms or enzymes
    • A23C9/13—Fermented milk preparations; Treatment using microorganisms or enzymes using additives
    • A23C9/1322—Inorganic compounds; Minerals, including organic salts thereof, oligo-elements; Amino-acids, peptides, protein-hydrolysates or derivatives; Nucleic acids or derivatives; Yeast extract or autolysate; Vitamins; Antibiotics; Bacteriocins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/116—Heterocyclic compounds
    • A23K20/132—Heterocyclic compounds containing only one nitrogen as hetero atom
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/45—Non condensed piperidines, e.g. piperocaine having oxo groups directly attached to the heterocyclic ring, e.g. cycloheximide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/38—Diluting, dispersing or mixing samples
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Food Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Birds (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pediatric Medicine (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Fodder In General (AREA)
  • Medicines Containing Plant Substances (AREA)

Claims (7)

1. Forbindelse med formlen (I) eller et farmaceutisk acceptabelt salt deraf, eller et veterinært salt deraf eller et egnet spiseligt salt deraf,
hvori R,, R2, R3 og R4 er Fl til anvendelse ved forebyggelse og/eller støttende behandling af en bakterieinfektion eller en mikrofloraubalance forårsaget af en bakterie valgt fra gruppen bestående af Streptococcus mutans, Salmonella typhi-murium og Escherichia coli.
2. Forbindelse til anvendelse ifølge krav 1, hvori forbindelsen anvendes ved forebyggelse af bakterieinfektionen.
3. Forbindelse til anvendelse ifølge krav 2, hvori bakterieinfektionen forårsager en sygdom valgt fra gruppen bestående af tandsygdom, periodontal sygdom, urinvejssygdom og tarmsygdom.
4. Kombination af en forbindelse med formlen (I) eller et egnet farmaceutisk, veterinært eller spiseligt acceptabelt salt deraf, hvori R,, R2, R3 og R4 er H, med et sakkarid, en iminocyclitol, probiotiske midler eller et antibakterielt middel, til anvendelse ifølge krav 1.
5. Kombinationen til anvendelse ifølge krav 4, hvori kombinationen er til sekventiel, samtidig eller særskilt indgivelse.
6. Farmaceutisk eller veterinær sammensætning, omfattende en kombination af en forbindelse med formlen (I) eller et egnet farmaceutisk eller veterinært acceptabelt salt deraf, hvori R,, R2, R3 og R4 er Fl, med et sakkarid, en iminocyclitol, probiotiske midler eller et antibakterielt middel, sammen med farmaceutiske eller veterinære excipienser eller bærere, til anvendelse ifølge krav 1.
7. Fødevare-, kæledyrsfoder- eller fodersammensætning omfattende en kombination af en forbindelse med formlen (I) eller et spiseligt acceptabelt salt deraf, hvori R-,, R2, R3 og R4 er H, med et sakkarid, en iminocyclitol eller probiotiske midler, til anvendelse ifølge krav 2.
DK11710197.2T 2010-03-25 2011-03-24 Anvendelse af D-fagomin som hæmmer af bakteriel vedhæftning til epiteliale celler DK2549994T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP10382068 2010-03-25
PCT/EP2011/054561 WO2011117362A1 (en) 2010-03-25 2011-03-24 Use of iminocyclitols as inhibitors of bacterial adherence to epithelial cells

Publications (1)

Publication Number Publication Date
DK2549994T3 true DK2549994T3 (da) 2015-11-09

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Family Applications (1)

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DK11710197.2T DK2549994T3 (da) 2010-03-25 2011-03-24 Anvendelse af D-fagomin som hæmmer af bakteriel vedhæftning til epiteliale celler

Country Status (8)

Country Link
US (1) US9226517B2 (da)
EP (1) EP2549994B1 (da)
CN (1) CN102811720A (da)
DK (1) DK2549994T3 (da)
ES (1) ES2551408T3 (da)
MX (1) MX2012010988A (da)
PL (1) PL2549994T3 (da)
WO (1) WO2011117362A1 (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9987316B2 (en) 2012-09-14 2018-06-05 Case Western Reserve University Probiotic controlling fungi and uses thereof
EP2767284A1 (en) 2013-02-18 2014-08-20 Bioglane, S.L. D-Fagomine for the control of inflammatory processes related to an overactivation of the humoral immune response
CN103431180A (zh) * 2013-09-03 2013-12-11 湖北省农业科学院经济作物研究所 一种桑叶饲料的制备方法
WO2017131691A1 (en) 2016-01-28 2017-08-03 Kimberly-Clark Worldwide, Inc. Anti-adherent composition against dna viruses and method of inhibiting the adherence of dna viruses to a surface
US11168287B2 (en) 2016-05-26 2021-11-09 Kimberly-Clark Worldwide, Inc. Anti-adherent compositions and methods of inhibiting the adherence of microbes to a surface
CN107382826B (zh) * 2017-08-09 2020-01-14 江苏中兴药业有限公司 一种金荞麦中的荞麦碱及其含量测定方法
JP6808082B1 (ja) * 2019-12-27 2021-01-06 サントリーホールディングス株式会社 苦味が強化された緑茶飲料
WO2021132441A1 (ja) * 2019-12-27 2021-07-01 サントリーホールディングス株式会社 オフフレーバーが低減された緑茶飲料

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3009531B2 (ja) 1992-03-30 2000-02-14 サンスター株式会社 歯周病予防剤
GB9700233D0 (en) 1997-01-08 1997-02-26 Univ London Use of glycosidase inhibitors
DE60232077D1 (de) 2001-06-29 2009-06-04 Glykos Finland Oy Verwendung mindestens einer glycoinhibitor-substanz gegen infektionskrankheiten
JP2007230719A (ja) 2006-02-28 2007-09-13 Mec:Kk テンション付与装置
CN101129476B (zh) 2006-08-21 2013-07-24 中国医学科学院药物研究所 桑枝生物碱有效部位在制备降血糖药物中的应用
JP5327661B2 (ja) 2007-09-05 2013-10-30 国立大学法人岩手大学 免疫賦活剤
CN103083208A (zh) 2007-10-01 2013-05-08 高露洁-棕榄公司 含有植物提取物的口腔组合物
CN101606936B (zh) 2008-06-20 2011-12-28 中南大学 一种治疗糖尿病的药物组合物
WO2010029313A1 (en) 2008-09-11 2010-03-18 Summit Corporation Plc. Antiinfective compounds

Also Published As

Publication number Publication date
EP2549994B1 (en) 2015-08-05
MX2012010988A (es) 2012-10-15
ES2551408T3 (es) 2015-11-18
US20130011344A1 (en) 2013-01-10
WO2011117362A1 (en) 2011-09-29
CN102811720A (zh) 2012-12-05
EP2549994A1 (en) 2013-01-30
PL2549994T3 (pl) 2016-06-30
US9226517B2 (en) 2016-01-05

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